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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_8 | Pages 124 - 124
11 Apr 2023
Woodford S Robinson D Lee P Abduo J Dimitroulis G Ackland D
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Total temporomandibular joint (TMJ) replacements reduce pain and improve quality of life in patients suffering from end-stage TMJ disorders, such as osteoarthritis and trauma. Jaw kinematics measurements following TMJ arthroplasty provide a basis for evaluating implant performance and jaw function. The aim of this study is to provide the first measurements of three-dimensional kinematics of the jaw in patients following unilateral and bilateral prosthetic TMJ surgeries. Jaw motion tracking experiments were performed on 7 healthy control participants, 3 unilateral and 1 bilateral TMJ replacement patients. Custom-made mouthpieces were manufactured for each participant's mandibular and maxillary teeth, with each supporting three retroreflective markers anterior to the participant's lip line. Participants performed 15 trials each of maximum jaw opening, lateral and protrusive movements. Marker trajectories were simultaneously measured using an optoelectronic tracking system. Laser scans taken of each dental plate, together with CT scans of each patient, were used to register the plate position to each participant's jaw geometry, allowing 3D condylar motion to be quantified from the marker trajectories. The maximum mouth opening capacity of joint replacement patients was comparable to healthy controls with average incisal inferior translations of 37.5mm, 38.4mm and 33.6mm for the controls, unilateral and bilateral joint replacement patients respectively. During mouth opening the maximum anterior translation of prosthetic condyles was 2.4mm, compared to 10.6mm for controls. Prosthetic condyles had limited anterior motion compared to natural condyles, in unilateral patients this resulted in asymmetric opening and protrusive movements and the capacity to laterally move their jaw towards their pathological side only. For the bilateral patient, protrusive and lateral jaw movement capacity was minimal. Total TMJ replacement surgery facilitates normal mouth opening capacity and lateral and inferior condylar movements but limits anterior condylar motion. This study provides future direction for TMJ implant design


The Bone & Joint Journal
Vol. 106-B, Issue 3 Supple A | Pages 44 - 50
1 Mar 2024
Engh, Jr CA Bhal V Hopper, Jr RH

Aims. The first aim of this study was to evaluate whether preoperative renal function is associated with postoperative changes in whole blood levels of metal ions in patients who have undergone a Birmingham Hip Resurfacing (BHR) arthroplasty with a metal-on-metal bearing. The second aim was to evaluate whether exposure to increased cobalt (Co) and chromium (Cr) levels for ten years adversely affected renal function. Methods. As part of a multicentre, prospective post-approval study, whole blood samples were sent to a single specialized laboratory to determine Co and Cr levels, and the estimated glomerular filtration rate (eGFR). The study included patients with 117 unrevised unilateral BHRs. There were 36 females (31%). The mean age of the patients at the time of surgery of 51.3 years (SD 6.5), and they all had preoperative one-, four-, five-, and ten-year laboratory data. The mean follow-up was 10.1 years (SD 0.2). Results. Median Co levels at one year postoperatively increased significantly compared with the preoperative values, by a factor of 9.7, from 0.13 to 1.26 ppb (p < 0.001), and the median Cr levels increased significantly by a factor of 2.5, from 0.60 to 1.50 ppb (p < 0.001). Lower preoperative eGFRs were associated with significantly larger increases in Co at one year compared with the preoperative levels (ρ = -0.26; p = 0.005), but there was no relationship between preoperative eGFRs and changes in Cr at one year (ρ = -0.13; p = 0.153). Metal levels remained relatively constant with the passage of time, with a median ten-year value of 1.12 ppb for Co and 1.29 ppb for Cr. There was no significant relationship between the Co and Cr levels at ten-year follow-up and the change in eGFR from the preoperative level to that at ten years (ρ = -0.02; p = 0.827 for Co; ρ = -0.008; p = 0.933 for Cr). Conclusion. Although patients with lower preoperative eGFRs tended to have larger increases in Co levels at one year, increased metal levels for patients who underwent unilateral BHR did not adversely affect renal function during the first ten postoperative years. Cite this article: Bone Joint J 2024;106-B(3 Supple A):44–50


The Bone & Joint Journal
Vol. 101-B, Issue 1 | Pages 15 - 21
1 Jan 2019
Kelly MJ Holton AE Cassar-Gheiti AJ Hanna SA Quinlan JF Molony DC

Aims. The glenohumeral joint is the most frequently dislocated articulation, but possibly due to the lower prevalence of posterior shoulder dislocations, approximately 50% to 79% of posterior glenohumeral dislocations are missed at initial presentation. The aim of this study was to systematically evaluate the most recent evidence involving the aetiology of posterior glenohumeral dislocations, as well as the diagnosis and treatment. Materials and Methods. A systematic search was conducted using PubMed (MEDLINE), Web of Science, Embase, and Cochrane (January 1997 to September 2017), with references from articles also evaluated. Studies reporting patients who experienced an acute posterior glenohumeral joint subluxation and/or dislocation, as well as the aetiology of posterior glenohumeral dislocations, were included. Results. A total of 54 studies met the inclusion criteria. In total, 182 patients were included in this analysis; study sizes ranged from one to 66 patients, with a mean age of 44.2 years (. sd. 13.7). There was a higher proportion of male patients. In all, 216 shoulders were included with 148 unilateral injuries and 34 bilateral. Seizures were implicated in 38% of patients (n = 69), with falls, road traffic accidents, electric shock, and iatrogenic reasons also described. Time to diagnosis varied across studies from immediate up to a delay of 25 years. Multiple associated injuries are described. Conclusion. This review provides an up-to-date insight into the aetiology of posterior shoulder dislocations. Our results showed that seizures were most commonly implicated. Overall, reduction was achieved via open means in the majority of shoulders. We also found that delayed diagnosis is common


The Bone & Joint Journal
Vol. 102-B, Issue 10 | Pages 1311 - 1318
3 Oct 2020
Huang Y Gao Y Li Y Ding L Liu J Qi X

Aims. Morphological abnormalities are present in patients with developmental dysplasia of the hip (DDH). We studied and compared the pelvic anatomy and morphology between the affected hemipelvis with the unaffected side in patients with unilateral Crowe type IV DDH using 3D imaging and analysis. Methods. A total of 20 patients with unilateral Crowe-IV DDH were included in the study. The contralateral side was considered normal in all patients. A coordinate system based on the sacral base (SB) in a reconstructed pelvic model was established. The pelvic orientations (tilt, rotation, and obliquity) of the affected side were assessed by establishing a virtual anterior pelvic plane (APP). The bilateral coordinates of the anterior superior iliac spine (ASIS) and the centres of hip rotation were established, and parameters concerning size and volume were compared for both sides of the pelvis. Results. The ASIS on the dislocated side was located inferiorly and anteriorly compared to the healthy side (coordinates on the y-axis and z-axis; p = 0.001; p = 0.031). The centre of hip rotation on the dislocated side was located inferiorly and medially compared to the healthy side (coordinates on the x-axis and the y-axis; p < 0.001; p = 0.003). The affected hemipelvis tilted anteriorly in the sagittal plane (mean 8.05° (SD 3.57°)), anteriorly rotated in the transverse plane (mean 3.31° (SD 1.41°)), and tilted obliquely and caudally in the coronal plane (mean 2.04° (SD 0.81°)) relative to the healthy hemipelvis. The affected hemipelvis was significantly smaller in the length, width, height, and volume than the healthy counterpart. (p = 0.014; p = 0.009; p = 0.035; p = 0.002). Conclusion. Asymmetric abnormalities were identified on the affected hemipelvis in patients with the unilateral Crowe-IV DDH using 3D imaging techniques. Improved understanding of the morphological changes may influence the positioning of the acetabular component at THA. Acetabular component malpositioning errors caused by anterior tilt of the affected hemi pelvis and the abnormal position of the affected side centre of rotation should be considered by orthopaedic surgeons when undertaking THA in patients with Crowe-IV DDH. Cite this article: Bone Joint J 2020;102-B(10):1311–1318


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_9 | Pages 47 - 47
17 Apr 2023
Akhtar R
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To compare the efficacy of intra-articular and intravenous modes of administration of tranexamic acid in primary total knee arthroplasty in terms of blood loss and fall in haemoglobin level. Study Design: Randomized controlled trial. Duration of Study: Six months, from May 2019 to Nov 2019. Seventy-eight patients were included in the study. All patients undergoing unilateral primary total knee replacement were included in the study. Exclusion criteria were patients with hepatitis B and C, history of previous knee replacement, bilateral total knee replacement, allergy to TXA, Hb less than 11g/dl in males and less than 10g/dl in females, renal dysfunction, use of anticoagulants for 7 days prior to surgery and history of thromboembolic diseases. Patients were randomly divided into group A and B. Group A patients undergoing unilateral primary total knee replacement (TKR) were given intravenous tranexamic acid (TXA) while group B were infiltrated with intra-articular TXA. Volume of drain output, fall in haemoglobin (Hb) level and need for blood transfusion were measured immediately after surgery and at 12 and 24 hours post operatively in both groups. The study included 35 (44.87%) male and 43 (55.13%) female patients. Mean age of patients was 61 ± 6.59 years. The mean drain output calculated immediately after surgery in group A was 45.38 ± 20.75 ml compared with 47.95 ± 23.86 ml in group B (p=0.73). At 24 hours post operatively, mean drain output was 263.21 ± 38.50 ml in intravenous group versus 243.59 ± 70.73 ml in intra-articular group (p=0.46). Regarding fall in Hb level, both groups showed no significant difference (p>0.05). About 12.82% (n=5) patients in group A compared to 10.26% (n=4) patients required blood transfusion post operatively (p=0.72). Intra-articular and intravenous TXA are equally effective in patients undergoing primary total knee arthroplasty in reducing post-operative blood loss


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 12 | Pages 1659 - 1663
1 Dec 2010
Barg A Knupp M Hintermann B

The aim of this study was to compare the outcome of bilateral sequential total ankle replacement (TAR) with that of unilateral TAR. We reviewed 23 patients who had undergone sequential bilateral TAR under a single anaesthetic and 46 matched patients with a unilateral TAR. There were no significant pre-operative differences between the two groups in terms of age, gender, body mass index, American Society of Anaesthesiologists classification and aetiology of the osteoarthritis of the ankle. Clinical and radiological follow-up was carried out at four months, one and two years. After four months, patients with simultaneous bilateral TAR reported a significantly higher mean pain score than those with a unilateral TAR. The mean American Orthopaedic Foot and Ankle Society hindfoot score and short-form 36 physical component summary score were better in the unilateral group. However, this difference disappeared at the one-and two-year follow-ups. Bilateral sequential TAR under one anaesthetic can be offered to patients with bilateral severe ankle osteoarthritis. However, they should be informed of the long recovery period


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 1 | Pages 64 - 68
1 Jan 2009
Kim Y Choi Y Kim J

We wished to determine whether simultaneous bilateral sequential total knee replacement (TKR) carried increased rates of mortality and complications compared with unilateral TKR in low- and high-risk patients. Our study included 2385 patients who had undergone bilateral sequential TKR under one anaesthetic and 719 who had unilateral TKR. There were no significant pre-operative differences between the groups in terms of age, gender, height, weight, body mass index, diagnosis, comorbidity and duration of follow-up, which was a mean of 10.2 years (5 to 14) in the bilateral and 10.4 years (5 to 14) in the unilateral group. The peri-operative mortality rate (eight patients, 0.3%) of patients who had bilateral sequential TKR was similar to that (five patients, 0.7%) of those undergoing unilateral TKR. In bilateral cases the peri-operative mortality rate (three patients, 0.4%) of patients at high risk was similar to that (five patients, 0.3%) of patients at low risk as it was also in unilateral cases (two patients, 1.0% vs three patients, 0.6%). There was no significant difference (p = 0.735) in either the overall number of major complications between bilateral and unilateral cases or between low- (p = 0.57) and high-risk (p = 0.61) patients. Also, the overall number of minor complications was not significantly different between the bilateral and unilateral group (p = 0.143). Simultaneous bilateral sequential TKR can be offered to patients at low and high risk and has an expected rate of complications similar to that of unilateral TKR


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 3 | Pages 316 - 320
1 Mar 2009
Kim Y Kwon O Kim J

We investigated whether simultaneous bilateral sequential total hip replacement (THR) would increase the rate of mortality and complications compared with unilateral THR in both low- and high-risk groups of patients. We enrolled 978 patients with bilateral and 1666 with unilateral THR in the study. There were no significant pre-operative differences between the groups in regard to age, gender, body mass index, diagnosis, comorbidity as assessed by the grading of the American Society of Anesthesiologists (ASA), the type of prosthesis and the duration of follow-up. The mean follow-up was for 10.5 years (5 to 13) in the bilateral THR group and 9.8 years (5 to 14) in the unilateral group. The peri-operative mortality rate of patients who had simultaneous bilateral THR (0.31%, three of 978 patients) was similar to that of patients with unilateral THR (0.18%, three of 1666 patients). The peri-operative mortality rate of patients in the bilateral group was similar in high risk and low risk patients (0.70%, two of 285 patients vs 0.14%, one of 693 patients) and this was also true in the unilateral THR group (0.40%, two of 500 patients vs 0.09%, one of 1166 patients). Patients with bilateral THR required more blood transfusions and a longer hospital stay than those in the unilateral THR group. There was no significant difference (p = 0.32) in the overall number of complications between the groups. This was also true for the low-risk (p = 0.81) vs high-risk (p = 0.631) patients. Our findings confirm that simultaneous sequential bilateral THR is a safe option for patients who are considered to be either high or low risk according to the ASA classification


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_4 | Pages 130 - 130
1 Apr 2019
Tamura K Takao M Hamada H Sakai T Sugano N
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Introduction. Most of patients with unilateral hip disease shows muscle volume atrophy of pelvis and thigh in the affected side because of pain and disuse, resulting in reduced muscle weakness and limping. However, it is unclear how the muscle atrophy correlated with muscle strength in the patient with hip disorders. A previous study have demonstrated that the volume of the gluteus medius correlated with the muscle strength by volumetric measurement using 3 dimensional computed tomography (3D-CT) data, however, muscles influence each other during motions and there is no reports focusing on the relationship between some major muscles of pelvis and thigh including gluteus maximus, gluteus medius, iliopsoas and quadriceps and muscle strength in several hip and knee motions. Therefore, the purpose of the present study is to evaluate the relationship between muscle volumetric atrophy of major muscles of pelvis and thigh and muscle strength in flexion, extension and abduction of hip joints and extension of knee joint before surgery in patients with unilateral hip disease. Material and Methods. The subjects were 38 patients with unilateral hip osteoarthritis, who underwent hip joint surgery. They all underwent preoperative computed tomography (CT) for preoperative planning. There were 6 males and 32 females with average age 59.5 years old. Before surgery, isometric muscle strength in hip flexion, hip extension, hip abduction and knee extension were measured using a hand held dynamometer (µTas F-1, ANIMA Japan). Major muscles including gluteus maximus, gluteus medius, iliopsoas and quadriceps were automatically extracted from the preoperative CT using convolutional neural networks (CNN) and were corrected manually by the experienced surgeon. The muscle volumetric atrophy ratio was defined as the ratio of muscle volume of the affected side to that of the unaffected side. The muscle weakness ratio was defined as the ratio of muscle strength of the affected side to that of the unaffected side. The correlation coefficient between the muscle atrophy ratio and the muscle weakness ratio of each muscle were calculated. Results. The average muscle atrophy ratio was 84.5% (63.5%–108.2%) in gluteus maximus, 86.6% (65.5%–112.1%) in gluteus medius, 81.0% (22.1%–130.8%) in psoas major, and 91.0% (63.8%–127.0%) in quadriceps. The average muscle strength ratio was 71.5% (0%–137.5%) in hip flexion, 88.1% (18.8%–169.6%) in hip abduction, 78.6% (21.9%–130.1%) in hip extension and 84.3% (13.1%–122.8%) in knee extension. The correlation coefficient between the muscle atrophy and the ratio of each muscle strength between the affected and unaffected side were shown in Table 1. Conclusion. In conclusion, the muscle atrophy of gluteus medius muscle, psoas major muscle and quadriceps muscle significantly correlated with the muscle weakness in hip flexion. The muscle atrophy of psoas major muscle and quadriceps muscle also significantly correlated with the muscle weakness in knee extension. There were no significant correlation between the muscle atrophy and the muscle weakness in hip extension and abduction


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_II | Pages 62 - 62
1 Feb 2012
Debnath U Freeman B Tokala P Grevitt M Webb J
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We report a prospective case-series study to evaluate the results of non-operative and operative treatment of symptomatic unilateral lumbar spondylolysis. Non-operative treatment results in healing in most patients with symptomatic unilateral spondylolysis. Surgery however is indicated when symptoms persist beyond a reasonable time affecting the quality of life in young patients particularly the athletic population. We treated 41 patients [31 male, 10 female] with suspected unilateral lumbar spondylolysis. Thirty-one patients were actively involved in sports at various levels. Patients with a positive stress reaction on SPECT imaging underwent a strict protocol of activity restriction, bracing and physical therapy for 6 months. At the end of six months, patients who remained symptomatic underwent a Computed Tomography [CT] scan to confirm the persistence of a spondylolysis. Seven patients subsequently underwent a direct repair of the defect using the modified Buck's Technique. Baseline Oswestry disability index [ODI] and Short-Form-36 [SF-36] scores were compared to two year ODI and SF-36 scores for all patients. In the non-operated group, the mean pre-treatment ODI was 36 [SD=10.5], improving to 6.2 [SD=8.2] at two years. In SF-36 scores, the physical component of health [PCS] improved from 30.7 [SD=3.2] to 53.5 [SD =6.5] [p<0.001], and the mean score for the mental component of health [MCS] improved from 39 [SD=4.1] to56.5 [SD=3.9] [p<0.001] at two years. 20/31 patients resumed their sporting career within 6 months of onset of treatment, a further 4/31 patients returned to sports within one year. The seven patients who remained symptomatic at six months underwent a unilateral modified Buck's Repair. The most common level of repair was L5 (n=4). The mean pre-operative ODI was 39.4 (SD=3.6) improving to 4.4 (SD=4) at the latest follow-up. The mean score of PCS [SF-36] improved from 29.6 [SD=4.4] to 51.2 [SD=5.2] (SD=5.2) (p<0.001) and the mean score of MCS (SF-36) improved from 38.7 (SD=1.9) to 55.5 (SD=5.4) (p<0.001). A specific protocol of conservative treatment for patients with a unilateral lumbar spondylolysis resulted in a high rate of success with 83% of patients avoiding surgery. If symptoms persist beyond a reasonable period (i.e. 6 months) and reverse gantry CT scan confirms a non-healing defect of the pars interarticularis one may consider a unilateral direct repair of the defect with good outcome ultimately


Background. Direct anterior approach (DAA), total hip arthroplasty (THA, performed with the patient in the supine position, creates a unique opportunity to do bilateral THA under one anesthesia. Previous studies evaluating this option are limited by small sample size or lack of control group. The purpose of this study is to compare early clinical outcomes of simultaneous bilateral, unilateral and staged bilateral DAA-THA. Methods. Using an institutional registry database, we reviewed 3977 DAA-THA performed in 3334 patients at minimum 90-days follow up. A single surgeon performed all surgeries. Simultaneous bilateral DAA-THA group included 512 hips in 256 patients, unilateral DAA-THA group 2691 hips and staged bilateral DAA-THA group 774 hips in 387 patients. We reviewed 90-day postoperative complications, readmissions, length of stay, and rate of home discharge between all three groups. Results. There were no statistical differences in readmission (range 0.77–1.8%), postoperative clinical complications, and rate of home discharge (96.1–98.1%) between simultaneous bilateral, unilateral, or staged bilateral groups. The number of transfusions in the simultaneous bilateral group (9/256, 3.5%) was significantly higher than in the unilateral (24/2691, 0.89%, p=0.002) or the staged bilateral group (4/387, 1.0%, p=0.04). The total length of stay (LOS) in the simultaneous bilateral group (1.8 ± 0.8 days) was longer (p<0.001) than in the unilateral group (1.2 ± 1.0 days) but shorter (p<0.001) than the two added LOS in the staged bilateral group (2.8 ± 2.2 days). Conclusion. Our large cohort in a single surgeon case showed that simultaneous bilateral DAA-THA is comparable with unilateral or staged bilateral surgery in regards to postoperative clinical complications, readmission rate, and rate of home discharge but with an increased rate of transfusion. We believe that simultaneous bilateral DAA-THA is a reasonable and safe option in properly selected patients who require bilateral THA


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_11 | Pages 47 - 47
1 Aug 2018
Zhang H
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To investigate the clinical results of capsular arthroplasty in the treatment of young patients with unilateral hip dislocation. We retrospectively evaluated all patients who had the capsular arthroplasty from June 2012 to September 2016 in our department. Hips were evaluated using hip Harris score (HHS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score. The Tonnis osteoarthritis grade and Severin classification were used to access the radiographic outcomes. Fifty-nine patients (10 males and 49 females) with an average of 16.8y (range: 8–26y) were followed by a mean of 32.1 months (range: 12.5–66.0 months). The mean HHS was 83.4 (range: 31.2–99) and WOMAC score was 12.3 (range: 0–49) at the final follow up. Multivariate analysis revealed that the poor capsular quality (OR=8.29) was associated with the poor result. The thicker capsule (OR=0.83) and bigger femoral head (OR=0.73) were associated with the good result. There were 15 patients (25.4%) identified as Tonnis grade 0, 21 patients (35.6%) as grade 1, 18 patients (30.5%) as grade 2 and 5 patients (8.5%) as grade 3. According to Severin classification, 28 patients (47.6%) were regarded as class I, 22 patients (37.3%) as II, 7 patients (11.9%) as III and 2 patients (3.4%) as IV. One patient underwent THA after 41.5 months. The joint stiffness was the most common complication (10.2%). We confirmed the efficacy of the capsular arthroplasty in the treatment of young patients with unilateral hip dislocation. The capsular quality and the size of femoral head were associated with the clinical results


The Journal of Bone & Joint Surgery British Volume
Vol. 64-B, Issue 3 | Pages 344 - 348
1 Jun 1982
Porter R Park W

Five vertebrae with unilateral spondylolysis are presented. The associated asymmetry of the posterior elements supports the concept of a localised form of growth deficiency. The defect is difficult to demonstrate radiologically, and is perhaps present more frequently than is recognised. It should be suspected clinically from asymmetry of the neural arch and from unilateral wedging of the vertebral body, and may be demonstrated by further radiographic examination. The clinical significance is uncertain, but one patient is presented in whom unilateral spondylolysis was associated with intermittent sciatic pain


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_4 | Pages 123 - 123
1 Mar 2021
Jelsma J Schotanus M van Kuijk S Buil I Heyligers I Grimm B
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Hip resurfacing arthroplasty (HRA) became a popular procedure in the early 90s because of the improved wear characteristic, preserving nature of the procedure and the optimal stability and range of motion. Concerns raised since 2004 when metal ions were seen in blood and urine of patients with a MoM implant. Design of the prosthesis, acetabular component malpositioning, contact-patch-to-rim distance (CPR) and a reduced joint size all seem to play a role in elevated metal ion concentrations. Little is known about the influence of physical activity (PA) on metal ion concentrations. Implant wear is thought to be a function of use and thus of patient activity levels. Wear of polyethylene acetabular bearings was positively correlated with patient's activity in previous studies. It is hypothesized that daily habitual physical activity of patients with a unilateral resurfacing prosthesis, measured by an activity monitor, is associated with habitual physical activity. A prospective, explorative study was conducted. Only patients with a unilateral hip resurfacing prosthesis and a follow-up of 10 ± 1 years were included. Metal ion concentrations were determined using ICP-MS. Habitual physical activity of subjects was measured in daily living using an acceleration-based activity monitor. Outcome consisted of quantitative and qualitative activity parameters. In total, 16 patients were included. 12 males (75%) and 4 females (25%) with a median age at surgery of 55.5 ± 9.7 years [43.0 – 67.9] and median follow-up of 9.9 ± 1.0 years [9.1 – 10.9]. The median cobalt and chromium ion concentrations were 25 ± 13 and 38 ± 28 nmol/L. A significant relationship, when adjusting for age at surgery, BMI, cup size and cup inclination, between sit-stand transfers (p = .034) and high intensity peaks (p = .001) with cobalt ion concentrations were found (linear regression analysis). This study showed that a high number of sit-stand transfers and a high number of high intensity peaks is significantly correlated with high metal ion concentrations, but results should be interpreted with care. For patients it seems save to engage in activities with low intensity peaks like walking or cycling without triggering critical wear or metal ions being able to achieve important general health benefits and quality of life, although the quality (high intensity peaks) of physical activity and behaviour of patients (sit-stand-transfers) seem to influence metal ion concentrations


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 10 | Pages 1456 - 1459
1 Oct 2010
Blecher R Geftler A Anekstein Y Mirovsky Y

Traumatic unilateral facet dislocation of the lumbosacral junction without fracture or with non-displaced fractures of adjacent vertebrae is extremely rare. We describe a case of a young male who sustained a unilateral facet dislocation of the lumbosacral junction in a motor vehicle accident. The unusual features of this case include an unremarkable physical and neurological examination on presentation and absence of other substantial vertebral or extra-vertebral injuries


The Bone & Joint Journal
Vol. 100-B, Issue 4 | Pages 527 - 534
1 Apr 2018
Hansson E Hagberg K Cawson M Brodtkorb TH

Aims. The aim of this study was to compare the cost-effectiveness of treatment with an osseointegrated percutaneous (OI-) prosthesis and a socket-suspended (S-) prosthesis for patients with a transfemoral amputation. Patients and Methods. A Markov model was developed to estimate the medical costs and changes in quality-adjusted life-years (QALYs) attributable to treatment of unilateral transfemoral amputation over a projected period of 20 years from a healthcare perspective. Data were collected alongside a prospective clinical study of 51 patients followed for two years. Results. OI-prostheses had an incremental cost per QALY gained of €83 374 compared with S-prostheses. The clinical improvement seen with OI-prostheses was reflected in QALYs gained. Results were most sensitive to the utility value for both treatment arms. The impact of an annual decline in utility values of 1%, 2%, and 3%, for patients with S-prostheses resulted in a cost per QALY gained of €37 020, €24 662, and €18 952, respectively, over 20 years. Conclusion. From a healthcare perspective, treatment with an OI-prosthesis results in improved quality of life at a relatively high cost compared with that for S-prosthesis. When patients treated with S-prostheses had a decline in quality of life over time, the cost per QALY gained by OI-prosthesis treatment was considerably reduced. Cite this article: Bone Joint J 2018;100-B:527–34


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_8 | Pages 108 - 108
1 Apr 2017
Bhattacharjee A Freeman R Roberts A Kiely N
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Methods. A retrospective review of 80 patients with unilateral slipped capital femoral epiphysis from 1998–2012 was undertaken to determine the outcome of the unaffected hip. All patients were treated with either prophylactic single Richards screw fixation or observation of the uninvolved hip and were followed up for at least 12 months. The unaffected hip of 44 patients (mean age 12.6 years, range 9–17) had simultaneous prophylactic fixation and 36 patients (mean age 13.4 years, range 9–17.4) were managed with observation. Results. Sequential slip of the unaffected hip was noted in 10 patients (28 per cent) in the observation group and only in 1 patient (2 per cent) in the group managed with prophylactic fixation. A Fisher's exact test showed significantly high incidence of sequential slip in unaffected hips when managed with regular observation (p-value 0.002). Only 3 cases had symptomatic hardware on the unaffected side after prophylactic fixation with one requiring revision of the metal work; one had superficial wound infection treated with antibiotics. No cases had AVN or chondrolysis. Conclusion. Simultaneous prophylactic fixation of the unaffected hip significantly reduces the incidence of sequential slip in unilateral SCFE with minimal complications. Level of evidence. III


The Journal of Bone & Joint Surgery British Volume
Vol. 84-B, Issue 1 | Pages 104 - 107
1 Jan 2002
Jari S Paton RW Srinivasan MS

Between 1992 and 1997, we undertook a prospective, targeted clinical and ultrasonographic hip screening programme to assess the relationship between ultrasonographic abnormalities of the hip and clinical limitation of hip abduction. A total of 5.9% (2 of 34) of neonatal dislocatable hips and 87.5% (7 of 8) of ‘late’ dislocated hips seen after the age of six months, presented with unilateral limitation of hip abduction. All major (Graf type III) and 44.5% of minor (Graf type II) dysplastic hips presented with this sign. Statistically, bilateral limitation of hip abduction was not a useful clinical indicator of underlying hip abnormality because of its poor sensitivity, but unilateral limitation of abduction of the hip was a highly specific (90%) and reasonably sensitive sign (70%). It was more sensitive than the neonatal Ortolani manoeuvre, which has been considered to be the method of choice. It was, however, not sensitive enough to be of value as a routine screening test in developmental dysplasia of the hip. We consider unilateral limitation of hip abduction to be an important clinical sign and its presence in an infant over the age of three to four months makes further investigation essential


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_2 | Pages 34 - 34
1 Jan 2017
Kuo M Hong S Lu T Wang J
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Posterior cruciate ligament deficiency (PCLD) leads to structural and proprioceptive impairments of the knee, affecting the performance of daily activities including obstacle-crossing. Therefore, identifying the biomechanical deficits and/or strategies during this motor task would be helpful for rehabilitative and clinical management of such patients. A safe and successful obstacle-crossing requires stability of the body and sufficient foot clearance of the swing limb. Patients with PCLD may face demands different from normal when negotiating obstacles of different heights. The objective of this study was thus to identify the biomechanical deviations/strategies of the lower limbs in unilateral PCLD during obstacle-crossing using motion analysis techniques. Twelve patients with unilateral PCLD and twelve healthy controls participated in the current study with informed written consent. They were asked to walk and cross obstacles of heights of 10%, 20% and 30% of their leg lengths at self-selected speeds. The PCLD group was asked to cross the obstacles with each of the affected and unaffected limb as the leading limb, denoted as PCLD-A and PCLD-U, respectively. The kinematic and kinetic data were measured with a 7-camera motion analysis system (Vicon, Oxford Metrics, U.K.) and two force plates (AMTI, U.S.A.). The angles of the stance and swing limbs (crossing angles) and the moments of the stance limbs (crossing moments) for each joint in the sagittal plane when the leading limb was above the obstacle were calculated for statistical analysis. A 3 by 2, 2-way mixed-model analysis of variance with one between-subject factor (PCLD-A vs. Control, and PCLD-U vs. Control) and one within-subject factor (obstacle height) was performed (α=0.05). Paired t-test was used to compare the variables between PCLD-A and PCLD-U (α=0.05). SAS version 9.2 was used for all statistical analysis. When the leading toe was above the obstacle, the PCLD group showed significantly greater hip flexion in the swing limb but decreased dorsiflexion in the stance limb, both in PCLD-A and PCLD-U (P<0.05). Greater knee flexion and greater ankle dorsiflexion were found in the leading limb in PCLD-A (P<0.05). Meanwhile, the PCLD group showed significantly decreased ankle plantarflexor but increased knee extensor crossing moments in the stance limb compared with the Control (P<0.05). None of the calculated variables were found to be significantly different between PCLD-A and PCLD-U (P>0.05). When crossing the obstacle, patients with PCLD reduced ankle plantarflexor moments that were mainly produced by the gastrocnemius. This may help reduce the posterior instability of the affected knee. Greater knee extensor crossing moments may also help reduce the posterior instability of the standing knee when the leading toe was above the obstacle. The changed joint kinetics as a result of PCLD were not only seen on the affected side but also on the unaffected side during obstacle-crossing. This symmetrical pattern may be necessary in performing functional activities that may require either the affected side or the unaffected side leading. These results suggest that rehabilitative intervention, including muscular strengthening, on both affected and unaffected sides are necessary in patients with unilateral PCLD


Introduction. Limb length discrepancy (LLD) is one of the major reasons of dissatisfaction after total hip arthroplasty(THR) and limb equalization after THR in unilateral developmental dysplasia of the hip (DDH) is very important. study designed to measure the difference of adult femoral length between normal and dislocated hip in unilateral DDH. Method. Sixty patients with unilateral high riding DDH (crow type 3,4) who were underwent THR included. All the cases had digital lower limb scanograms. Exclusion criteria was any previous hip or femur surgery, any rheumatoid disease, history of any disease that affect the growth. All the scanograms measured by one fellowship of adult reconstruction and one radiologist specialized in musculoskeletal imaging. Each one repeated the measurements two months later blindly and inter observer and intra observer reliability checked. Each one measured femoral length in both sides from greater trochanter(GT), to the distal surface of the femoral condyles. Results. 59 female and one males included. Average age was 27.5 years (19–50 years). Inter observer reliability index were excellent (ICC 98%). Only 6 cases (10%) had exactly equal femoral length, 31(52%) cases were longer on the dislocated side and 23 (38%) cases were shorter. Average overgrowth was 6.1 mm (Range: 1–22) and average undergrowth was 10.7 (Range 1–21). 35 cases (58.3%) cases had 5 mm or more differences and 30% had 5–10 mm .17 cases (28.3%) had at least 10 mm difference that 8 cases (13%) had shorter and 9 cases (15%) had longer femur on dislocated side. Maximum difference was 22 mm over length on dislocated side. Conclusions. More than half of patients with unilateral high riding DDH have longer femur on the dislocated side and 15% of them are longer than 10 mm. we recommend to get the scanograms in all the unilateral DDH cases to avoid post-operative limb discrepancy and detecting the amount of shortening in cases that need femoral shortening


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_4 | Pages 22 - 22
1 Jan 2013
Feldwieser F Sparkes V
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Background. Active therapeutic exercises during unstable and unilateral conditions using body weight for resistance are often used in the rehabilitation of low back pain (LBP). In LBP patient's unilateral atrophy of the spinal muscles is reported. To address these deficits understanding side to side muscle activity using surface Electromyography (SEMG) can help clinicians design exercises that specifically address these deficits. Aim: To identify the effects of unilateral and unstable bridging exercises on trunk muscle activity. Methods. Using a repeated measures design, SEMG side to side measurements of lumbar Multifidus (MF), Iliocostalis Thoracis (ICT), Rectus Abdominis (RA) and External Oblique (EO) were conducted on 20 healthy subjects (16 female, age 25.45±3.57 years, height 166±0.8 cm, weight 63.35±12.70 kg. Mean Body Mass Index 23) during 8 supine bridging exercises with stable, unstable and unilateral conditions. Results. Muscle activity was significantly influenced by unilateral and unstable conditions. Highest SEMG activity was found in MF and ICT, lowest in RA and EO in all exercises. Highest SEMG activity of all investigated muscles was found during all unstable or unilateral conditions and lowest activity during standard bridging exercises. Unilateral exercises increased ipsilateral EMG activity on the unsupported side of all investigated muscles. Conclusion. The results suggest that unilateral atrophied muscles can be specifically trained by using unilateral bridging exercises. The intensity of the exercises can be adapted to subjects' ability by including various unstable or unilateral conditions within the bridging exercise, since individual muscle activity ranges from low to high activity between the exercises. Conflicts of Interest. None. Source of Funding. None. I confirm that this abstract has not been previously published in whole or substantial part nor has it been presented previously at a national meeting


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_11 | Pages 23 - 23
1 Dec 2020
MERTER A
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With the increase in the elderly population, there is a dramatic increase in the number of spinal fusions. Spinal fusion is usually performed in cases of primary instability. However it is also performed to prevent iatrogenic instability created during surgical treatment of spinal stenosis in most cases. In literature, up to 75% of adjacent segment disease (ASD) can be seen according to the follow-up time. 1. Although ASD manifests itself with pathologies such as instability, foraminal stenosis, disc herniation or central stenosis. 1,2. There are several reports in the literature regarding lumbar percutaneous transforaminal endoscopic interventions for lumbar foraminal stenosis or disc herniations. However, to the best our knowledge, there is no report about the treatment of central stenosis in ASD. In this study, we aimed to investigate the short-term results of unilateral biportal endoscopic decompressive laminotomy (UBEDL) technique in ASD cases with symptomatic central or lateral recess stenosis. The number of patients participating in the prospective study was 8. The mean follow-up was 6.9 (ranged 6 to 11) months. The mean age of the patients was 68 (5m, 3F). The development of ASD time after fusion was 30.6 months(ranged 19 to 42). Mean fused segments were 3 (ranged 2 to 8). Preoperative instability was present in 2 of the patients which was proven by dynamic lumbar x-rays. Preoperative mean VAS-back score was 7.8, VAS Leg score was 5.6. The preoperative mean JOA (Japanese Orthopaedic Association) score was 11.25. At 6th month follow-up, the mean VAS back score of the patients was 1, and the VAS leg score was 0.5. This improvement was statistically significant (p = 0.11 and 0.016, respectively). The mean JOA score at the 6th month was 22.6 and it was also statistically significant comparing preoperative JOA score(p = 0.011). The preoperative mean dural sac area measured in MR was 0.50 cm2, and it was measured as 2.1 cm. 2. at po 6 months.(p = 0.012). There was no progress in any patient's instability during follow-up. In orthopedic surgery, when implant related problems develop in any region of body (pseudoarthrosis, infection, adjacent fracture, etc.), it is generally treated by using more implants in its final operation. This approach is also widely used in spinal surgery. 3. However, it carries more risk in terms of devoloping ASD, infection or another complications. In the literature, endoscopic procedures have almost always been used in the treatment of ventral pathologies which constitute only 10%. In ASD, disease devolops as characterized by wide facet joint arthrosis and hypertrophied ligamentum flavum in the cranial segment and it is mostly presented both lateral recess and santal stenosis symptoms (39%). In this study, we found that UBEDL provides successful results in the treatment of patients without no more muscle and ligament damage in ASD cases with spinal stenosis. One of the most important advantages of UBE is its ability to access both ventral and dorsal pathologies by minimally invasive endoscopic aproach. I think endoscopic decompression also plays an important role in the absence of additional instability at postoperatively in patients. UBE which has already been described in the literature given successful results in most of the spinal degenerative diseases besides it can also be used in the treatment of ASD. Studies with longer follow-up and higher patient numbers will provide more accurate results


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 276 - 276
1 Mar 2003
Fernández-Palazzi F Rivas S Viso R
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Europeam Group of Neuro-orthopaedic (GLAENeO), Caracas, The prevention of a dislocated hip is one of the aims of early surgery in Cerebral Palsy children, specially those severely involved. We performed a retrospective study of those cerebral palsy patients operated of adductor tenotomy between 1975 and 1995 with a total of 1474 patients. We grouped them in those who had a unilateral tenotomy and those who had a bilateral tenotomy as primary surgery. Of these only 8% had an obturator neurectomy, without walking ability, and 92 % had it not. Age at surgery varied from 6 months to 8 years of age with a mean of 4 years and 3 months. Group I: 792 patients (53.7 %) with unilateral adductor contracture, sustained a unilateral adductor tenotomy. Of these patients a total of 619 (78, 2 %) required a contralateral adductor tenotomy at a mean of 3 years and 6 months. Group II: 682 patients (46, 3 %) with bilateral adductor contracture that had a bilateral adductor tenotomy in one stage. Of the 792 patients that sustained a two stage adductor tenotomy, 123 (20%) presented a unilateral dislocated hip and of these 115 (93 %) occurred in the hip operated secondly at a mean of 1 year post tenotomy. Of the 682 patients with bilateral adductor tenotomies only 7 (1 %) had a dislocated hip 2 years post tenotomy. Of the 72 dislocated hips, 12 (59 %) were quadriplegics, 28 (22 %) were diplegic, 21 (18 %) hemiplegics and 1 (1 %) tetraplegic. Of the 619 patients tenotomized in two stages, in 143 the diaphyseal – cervical angle was 155 ° (23,1 %), at a mean of 6 and a half years of age and 3 years post the second tenotomy. In 102 of these patients (71 %) a varus derotation osteotomy was performed in the hip operated in the second act with further dislocation of the hip in 20 cases (20 %). Of the 685 patients with bilateral tenotomy in one stage, varus derotation osteotomy was required in 68 (68 %) at a mean of 6 years of age with only a 3 % of dislocations in this group. In view of these results we recommend a bilateral adductor tenotomy be performd regardless of a difference in the degree of contracture of both sides, thus coordinating the forces and avoid further dislocation the hip


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 468 - 468
1 Apr 2004
Cross M Parish E
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Introduction The decision to perform bilateral total knee replacement (TKR) either simultaneously or as a staged procedure is made depending on the level of disease severity, comorbidities, total anaesthetic time and cost. We compared the outcomes of these two bilateral groups of patients with unilateral TKR. Methods Between August 1992 and December 2002 all patients requiring primary TKR received an uncemented, hydroxyapatite-coated, posterior cruciate ligament retaining prosthesis implanted by the senior author. All peri-operative complications were recorded prospectively, as were pre-operative and post-operative knee scores (Knee Society Clinical Rating Score) at three and six months, and one, two, five, and 10 years thereafter. Patients were divided into three groups being; simultaneous bilateral TKR (SIM), staged bilateral TKR (STA), and unilateral TKR (SIN) with the outcomes of each group compared for statistical significance. One thousand one hundred and forty patients (1638 knees) were included in the study. The majority of patients were female in the STA and SIN groups (60% and 53% respectively) and males in the SIM group (57%). There were 790 (SIM), 206 (STA), and 642 (SIN) knees with mean ages of 67 (SIM), 65 (STA), and 67 years (SIN). The primary diagnosis was OA in each of the groups (> 93%). Results Pre-operative and post-operative scores revealed no significant differences (p> .05) between the groups. Mean scores ranged from 94 to 98 pre-operatively and increased up to 182 to 187 at five years. Post-operative complications were significantly higher (p< .01) in both bilateral groups. There were 68 (17.2%) and 16 (15.5%) cases of thrombi in the SIM and STA groups respectively compared to 60 (9.3%) cases in the SIN group. Pulmonary emboli were also significantly higher in the bilateral groups compared to the unilateral group (p< .01). The rate of deep infection was higher (p=.09) in the STA group compared to the SIM and SIN groups (2.9% of patients compared to 1.1% and 1.4% respectively). There have been 10 revisions (four SIM, one STA, and five SIN) and two cases of peri-operative death (one STA, one SIM) both due to MI. Conclusions While simultaneous TKR has higher rates of post-operative complication compared to unilateral TKR, it is less than staged TKR. Therefore simultaneous bilateral knee replacements, when indicated, are the ideal treatment of choice compared to staged procedures


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_7 | Pages 92 - 92
1 Jul 2020
Khan J Akhtar RR Ahmed R
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To compare the efficacy of intra-articular and intravenous modes of administration of tranexamic acid in primary Total Knee Arthroplasty in terms of blood loss and fall in haemoglobin level. This randomized controlled trial was conducted from 12th May 2017 to 11th May 2017. Seventy eight patients were included in the study. Patients were randomly divided into group A and B. Group A patients undergoing unilateral primary total knee replacement (TKR) were given intravenous tranexamic acid (TXA) while group B were infiltrated with intra-articular TXA. Volume of drain output, fall in haemoglobin (Hb) level and need for blood transfusion were measured immediately after surgery and at 12 and 24 hours post operatively in both groups. The study included 35 (44.87%) male and 43 (55.13%) female patients. Mean age of patients was 61±6.59 years. The mean drain output calculated immediately after surgery in group A was 45.38±20.75 mL compared with 47.95±23.86 mL in group B (p=0.73). 24 hours post operatively, mean drain output was 263.21±38.50 mL in intravenous group versus 243.59±70.73 mL in intra-articular group (p=0.46). Regarding fall in Hb level, both groups showed no significant difference (p>0.05). 12.82% (n=5) patients in group A compared to 10.26% (n=4) patients required blood transfusion post operatively (p=0.72). Intra-articular and intravenous TXA are equally effective in patients undergoing primary total knee arthroplasty in reducing post operative blood loss. For any reader queries, please contact . drjunaidrmc@gmail.com


The Journal of Bone & Joint Surgery British Volume
Vol. 77-B, Issue 4 | Pages 615 - 619
1 Jul 1995
Fraser R Bourke H Broughton N Menelaus M

We reviewed 16 patients with spina bifida and unilateral dislocation of the hip at an average age of 17 years. Nine had a high neurological level (thoracic to L3) and seven a low lesion (L4 to sacral). We assessed the influence of unilateral dislocation of the hip on leg-length discrepancy, hip pain, hip stiffness and pressure sores of the ischial tuberosity. In non-walking patients with high-level lesions, unilateral dislocation gave little functional disability and did not appear to require reduction. In walking patients with low-level lesions, leg-length discrepancy led to a poor gait and functional problems which could be prevented by reduction of the dislocation. In all patients with low lesions, surgery was successful in maintaining reduction; in two of five patients with high lesions it was unsuccessful


Bone & Joint Research
Vol. 6, Issue 4 | Pages 216 - 223
1 Apr 2017
Ang BFH Chen JY Yew AKS Chua SK Chou SM Chia SL Koh JSB Howe TS

Objectives. External fixators are the traditional fixation method of choice for contaminated open fractures. However, patient acceptance is low due to the high profile and therefore physical burden of the constructs. An externalised locking compression plate is a low profile alternative. However, the biomechanical differences have not been assessed. The objective of this study was to evaluate the axial and torsional stiffness of the externalised titanium locking compression plate (ET-LCP), the externalised stainless steel locking compression plate (ESS-LCP) and the unilateral external fixator (UEF). Methods. A fracture gap model was created to simulate comminuted mid-shaft tibia fractures using synthetic composite bones. Fifteen constructs were stabilised with ET-LCP, ESS-LCP or UEF (five constructs each). The constructs were loaded under both axial and torsional directions to determine construct stiffness. Results. The mean axial stiffness was very similar for UEF (528 N/mm) and ESS-LCP (525 N/mm), while it was slightly lower for ET-LCP (469 N/mm). One-way analysis of variance (ANOVA) testing in all three groups demonstrated no significant difference (F(2,12) = 2.057, p = 0.171). There was a significant difference in mean torsional stiffness between the UEF (0.512 Nm/degree), the ESS-LCP (0.686 Nm/degree) and the ET-LCP (0.639 Nm/degree), as determined by one-way ANOVA (F(2,12) = 6.204, p = 0.014). A Tukey post hoc test revealed that the torsional stiffness of the ESS-LCP was statistically higher than that of the UEF by 0.174 Nm/degree (p = 0.013). No catastrophic failures were observed. Conclusion. Using the LCP as an external fixator may provide a viable and attractive alternative to the traditional UEF as its lower profile makes it more acceptable to patients, while not compromising on axial and torsional stiffness. Cite this article: B. F. H. Ang, J. Y. Chen, A. K. S. Yew, S. K. Chua, S. M. Chou, S. L. Chia, J. S. B. Koh, T. S. Howe. Externalised locking compression plate as an alternative to the unilateral external fixator: a biomechanical comparative study of axial and torsional stiffness. Bone Joint Res 2017;6:216–223. DOI: 10.1302/2046-3758.64.2000470


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_I | Pages 76 - 76
1 Jan 2004
Lee PTH Clarke MT Arora A Villar RN
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Aims: Cobalt (Co) and chromium (Cr) ion associated carcinogenesis and chromosomal damage in animals have raised concerns that metal-on-metal (MOM) total hip replacement (THR) in humans may produce the same effects over time. Considering that the risks may be related to the level of these ions in the body, this study compared the serum Co and Cr levels in patients with unilateral versus bilateral 28 mm diameter MOM THR. Methods: All patients having THR at our institution were prospectively registered on a computerised database. From our database, 108 Ultima MOM THR with 28 mm CoCrMo bearing were identified. After patient review in clinic and before blood results were known, patient matching was performed by date after surgery, activity level and weight. Using these stringent criteria, 11 unilateral THR could be adequately matched with 11 bilateral THR. Blood serum was taken with full anti-contamination protocols and serum analysed via inductively coupled plasma mass spectrometry (ICP-MS) Statistical analysis used the Mann-Whitney U test. Results: The median serum Co level after unilateral MOM THR was 22 nmol (range 15 to 37 nmol) compared to 42 nmol (range 19 to 221 nmol) for bilateral MOM THR (p=0.001). The median serum Cr level after unilateral MOM THR was 19 nmol (range 2 to 35 nmol) compared to 52 nmol (range 19 to 287 nmol) for bilateral MOM THR (p=0.04). Conclusions: This study has shown that the serum Co and Cr levels in patients with bilateral MOM THR are significantly higher than those with unilateral MOM THR. With levels of up to 50 times the upper of limit of normal, this finding may be of relevance for the development of potential long-term side effects


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 232 - 232
1 Sep 2005
Lee P Clarke M Arora A Villar R
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Aims: Elevated serum cobalt and chromium ion levels associated with carcinogenesis and chromosomal damage in animals has raised concerns that metal-on-metal (MOM) total hip replacement (THR) in humans may produce the same effects over time. Considering that the risks may be related to the level of these ions in the body, this study compared the serum cobalt and chromium ion levels in patients with unilateral versus bilateral 28 mm diameter MOM THR. Methods: All patients having THR at our institution were prospectively registered on a computerised database. From our database, we identified 108 patients with Ultima (Johnson and Johnson, Leeds) MOM THR with 28 mm bearing made of cobalt-chromium alloy. After patient review in clinic and before blood results were known, patient matching was performed by date after surgery at blood sampling, activity level and body mass. Using these stringent criteria, 11 unilateral THR could be adequately matched with 11 bilateral THR. Blood serum was taken with full anti-contamination protocols and serum analysed via inductively coupled plasma mass spectrometry. Statistical analysis used the Mann-Whitney U test. Results: The serum cobalt ion level after unilateral MOM THR was 4.4 times normal (median 22 nmol/L, range 15 to 37 nmol/L) compared to 8.4 times normal (median 42 nmol/L, range 19 to 221 nmol/L) for bilateral MOM THR (p=0.001). The serum chromium ion level after unilateral MOM THR was 3.8 times normal (median 19 nmol/L, range 2 to 35 nmol/L) compared to 10.4 times normal (median 52 nmol/L, range 19 to 287 nmol/L) for bilateral MOM THR (p=0.04). Conclusions: This study has shown that the serum cobalt and chromium ion levels in patients with bilateral MOM THR are significantly higher than those in patients with unilateral MOM THR. With levels of up to 50 times the upper limit of normal, this finding may be of relevance for the potential development of long-term side effects


The Journal of Bone & Joint Surgery British Volume
Vol. 73-B, Issue 6 | Pages 977 - 981
1 Nov 1991
Beyer C Cabanela M Berquist T

We treated 36 patients with unilateral facet dislocations or fracture-dislocations of the cervical spine at the Mayo Clinic between 1975 and 1986. Adequate records were available for 34: ten patients were treated by open reduction and posterior fusion, and 24 by nonoperative management. Of these, 19 had halo traction followed by halo-thoracic immobilisation, four had a simple cervicothoracic orthosis, and one received no active treatment. Anatomical reduction was achieved more frequently in the operative group (60% compared with 25%). Nonoperative treatment was more likely to result in cervical translation on flexion/extension lateral radiographs, and in significant symptoms. Only 36% of the patients treated by halo traction achieved anatomical alignment; in 25% halo traction failed to achieve or maintain any degree of reduction. During halo-thoracic immobilisation, half of the patients lost some degree of reduction and patient satisfaction with the appliance was low. Open reduction and internal fixation of unilateral facet injuries gave better results. 6


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 3 - 4
1 Mar 2010
Parsley BK Allan DG Dyrstad B Milbrandt JC
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Purpose: Metal-on-metal (MOM) bearing surfaces release ions locally and into the systemic circulation. This elevation raises concern about the long term effects of elevated metal ions. The goal of the present study was to monitor serum cobalt (Co) and chromium (Cr) levels in patients after MOM resurfacing hip arthroplasty with the Cormet 2000 prosthesis. We present here pilot data on Co and Cr levels in patients with bilateral versus unilateral hip resurfacing devices. Method: We prospectively collected patient characteristics, outcome, and serum samples from device implanted subjects at 6 months, 1, 2, and 3 years following surgery. Unilateral patients had one implant during the entire course of follow-up and bilateral patients were included after the second implant surgery was performed. Serum Co/Cr levels were determined using high-resolution inductively coupled plasma mass spectrometry. Students t-test was used to compare ion levels in two groups based on the number of resurfacing implants (bilateral versus unilateral). Results: 41 unilateral and 9 bilateral subjects were enrolled and followed for serum Co and Cr levels. In general, Co/Cr levels were increased at all time points when compared to control levels in both groups. Bilateral subjects had average serum levels concentrations significantly higher than those observed for unilateral cases (Co: 5.99 vs 2.56 μg/L (p=0.0001); Cr: 6.66 vs 3.60 (p=0.0009). Conclusion: Elevated serum Co/Cr levels were observed at all time points following implantation in both groups and serum levels were nearly 2 times higher in the bilateral group. Based on these preliminary findings, patients undergoing bilateral total hip resurfacing arthroplasty may need to be monitored more closely than those patients receiving unilateral devices. In addition, these bilateral cases may be at a greater risk of ion level toxicities than the unilateral population


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_4 | Pages 102 - 102
1 Feb 2017
Layne C Amador R Pourmoghaddam A Kreuzer S
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The number of hip arthroplasty procedures has steadily increased in the United States over the last decade [Wolford, et. al, 2015]. This trend will continue as this treatment is the most effective approach in relieving pain, improving mobility, reducing fall risk and improving the quality of life in patients with end-stage osteoarthritis. The effectiveness of recovery can be impacted by factors such as access to postoperative physical therapy regimens. During the recovery period, it is important for therapists to be guided in their therapeutic decision making by accurate data concerning the patient's performance on a variety of measures. This project is designed to map the gait recovery curves of individuals who have undergone unilateral hip arthroplasty. To date, eight individuals (4 females, mean age 64.9, SD 11.1) have participated in the study. Five of the patients were treated by traditional press-fit Accolade II implants (Stryker, Mahwah, NJ USA) through a direct anterior approach THA and the other three has been treated by using DAA THA and using neck preserving Minihip. TM. short stem implant (Corin Ltd., Cirencester, UK). Each participant walked on an instrumented treadmill as a self-selected speed for three minutes pre-surgery. Post-surgery data collections occurred at three and six weeks, and three and six months and employed the same treadmill speed as used prior to surgery. Bilateral lower limb kinematic data was collected with a 12 camera motion capture system Vicon® (Oxford Metrics, Oxford, UK) using reflective markers attached to the hip, knee, ankle, heel and toe. Force plates embedded in the treadmill provided kinetic data that aided in the detection of heel strike and toe off. The temporal features associated with gait, including stride, stance time and double support time were obtained for both the surgical and non-surgical limbs and were used to assess changes in performance during the recovery period. The stance and double support data were also converted to a percentage of stance values which provide additional insights into gait control strategies. Repeated measure MANOVAs were used to evaluate any potential differences in the variables either between limbs or over time. Results from the statistical testing revealed that there were no significant differences between the two limbs for either stride or stance time. This was expected since global asymmetrical gait would have led to the participants veer off of the treadmill. There was a main effect of ‘Time’ for both stride and stance times. Post hoc testing indicated that the 6-month post-surgery measures were significantly reduced when compared to the Pre-surgery and 3-week post-surgery measures. Similarly, there were no significant differences in double support times between the two legs but there was a main effect for time. Post hoc testing revealed that the 6-month post-surgery double support time was significantly less than the Pre-surgery and 3-week post-surgery measures. These significant changes clearly indicate that surgery is effective in improving gait parameters. Moreover, clinicians may want to consider assessing double support time as this measure is a particularly robust indicator of the effectiveness of unilateral hip arthroplasty


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXI | Pages 34 - 34
1 May 2012
J. G E. B L. R
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Introduction. In cases of unilateral clubfoot, the leg and foot is visually smaller than the opposite, uninvolved side. Parents want to know how much smaller the leg and foot will be. The purpose of this study was to answer this question and compare the results of children treated with a posterior medial release (PMR) with those treated with the Ponseti method (PM). Methods. This is a prospective, longitudinal study of calf circumference and foot length. We measured the calf circumference with a tape measure at the visually maximum girth of the uninvolved side and at the symmetrical position of the involved side. We measured each foot length from the tip of the hallux to the end of the heel. We recorded the measurements at each follow-up visit in a database and analysed the data using linear regression analysis. Results. We followed 93 children (65 PMR, 28 PM) for a mean of 68 months (SD 55, range 6-252) The ratio men/women was 53/40. Mean percent calf size difference was 9.83% (95%CL 8.74-10.92%). Mean percent foot size difference was 8.70% (95%CL 7.54-9.87%). From the numbers available, no differences between the two procedures are evident. Conclusion. Children with a unilateral clubfoot have c10% smaller calf circumference and foot length as compared to the uninvolved side. We found no differences between children treated with PMR or PM, implying the smaller size is intrinsic to the condition and not due to type of treatment


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 352 - 352
1 Mar 2004
Lee P Clarke M Arora A Villar R
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Aims: Cobalt (Co) and chromium (Cr) ion associated carcinogenesis and chromosomal damage in animals has raised concerns that metal-on-metal (MOM) total hip replacement (THR) in humans may produce the same effects over time. Considering that the risks may be related to the level of these ions in the body, this study compared the serum Co and Cr levels in patients with unilateral versus bilateral 28 mm diameter MOM THR. Methods: All patients having THR at our institution were prospectively registered on a computerised database. From our database, 108 Ultima MOM THR with 28 mm CoCrMo bearing were identiþed. After patient review in clinic and before blood results were known, patient matching was performed by date after surgery, activity level and weight. Using these stringent criteria, 11 unilateral THR could be adequately matched with 11 bilateral THR. Blood serum was taken with full anti-contamination protocols and serum analysed via atomic absorption spectrometry. Statistical analysis used the Mann-Whitney U test. Results: The median serum Co level after unilateral MOM THR was 22 nmol (range 15 to 37 nmol) compared to 42 nmol (range 19 to 221 nmol) for bilateral MOM THR (p=0.001). The median serum Cr level after unilateral MOM THR was 19 nmol (range 2 to 35 nmol) compared to 52 nmol (range 19 to 287 nmol) for bilateral MOM THR (p=0.04). Conclusions: This study has shown that the serum Co and Cr levels in patients with bilateral MOM THR are signiþcantly higher than those with unilateral MOM THR. With levels of up to 50 times the upper limit of normal, this þnding may be of relevance for the potential development of long-term side effects


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 130 - 130
1 Dec 2013
Morapudi S
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Introduction:. The clinical significance of serum metal ion levels alone in patients with stemmed MoM hip arthroplasty remains uncertain. This study aims to measure the metal ion levels in patients with unilateral and bilateral hip arthroplasty to see whether or not the patients with bilateral hips have higher metal ions. Patients and Methods. All the patients with bilateral MoM hip arthroplasty were identified from the research database. These patients were then matched with those in a similar age group who had a unilateral hip arthroplasty, but same University of California Los Angeles (UCLA) activity score. The UCLA activity scores along with other hip scores have been previously gathered for all the patients. Both sets of patients then had measurement of serum cobalt and chromium levels. The results were analyzed and compared. Results:. There were a total of 53 patients with bilateral hips and 53 matched patients with unilateral hips. The average serum Cobalt and Chromium levels were 34 nmol/L (range <10–76) and 23 nmol/L (range <10–104) respectively in the bilateral group; and 14 nmol/L (range <10–45) and 21 nmol/L (range <10–57) in the unilateral group. Given that the MHRA (UK) threshold levels deemed clinically significant are 120 nmol/L and 135 nmol/L for Cobalt and Chromium respectively; the results obtained here are not clinically significant. Conclusions:. One would normally expect, with mathematical reasoning, a patient with bilateral hip arthroplasty to have higher serum metal ion levels than a patient with unilateral arthroplasty. However, this study goes to show that it is not the case


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 138 - 138
1 Mar 2009
Ohnishi I Matsumoto T Matsuyama J Bessho M Ohashi S Sato W Okazaki H Nakamura K
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Ring frames have the advantage of allowing progressive correction. However, the available frames for complex deformities are heavy and bulky leading to poor compliance by patients. Also, the mounting procedure requires considerable expertise and skill. On the other hand, a unilateral external fixator has the advantages of less bulk and a lighter weight. Thus, it causes less disability and can achieve better patient compliance even with bilateral application. However, previous unilateral fixators have had various limitations with respect to deformity correction, such as restricted placement of hinges, restricted correction planes, and a limited range of correction angles. In addition, it was impossible to achieve progressive correction while fixation was maintained. To overcome these disadvantages of existing unilateral fixators, we developed a new fixator for gradual correction of multi-plane deformities including translational and rotation deformities. This unilateral external fixator is equipped with a universal bar link system. The link is constructed from three dials and two splines that are connecting the dials. The pin clamps are able to vary the direction of a pin cluster in the three dimensional planes. The system allows us to correct angulation, translation, rotation, and the combination of the above. In addition, open or closed hinge technique is available because the correction hinge can be placed right on the center of rotational angulation (CORA), or at any desired location, by adjusting the length of the link spline. By increasing the spline length, the virtual hinge can also be set far from the fixator. Gradual correction can be performed by rotating the three dials using a worm gear goniometer that is temporarily attached. A 3D reconstructed image of the bone is generated preoperatively. Preoperative planning can be done using this image. Mounting parameters are determined by postoperative AP and lateral computed radiography images. These postoperative images are matched with the pre-operative 3D CT image by 2D and 3D image registration. Then, the fixator can be virtually fixed to the bone. By performing virtual correction, it is possible to plan the correction procedure. The fixator is manipulated by rotating each of the three dials to the predetermined angles calculated by the software. Static load testing disclosed that the fixator could bear a load of 1700 N. No breakage or deformation of the fixator itself was recognized. Mechanical testing demonstrated that this new fixator has sufficient strength for full weight bearing, as well as sufficient fatigue resistance for repeated or prolonged use. The results of clinical application in patients with multi-plane femoral deformities were excellent, and correction with very small residual deformity was achieved in each plane


The Bone & Joint Journal
Vol. 96-B, Issue 9 | Pages 1161 - 1166
1 Sep 2014
Terjesen T

The aim of this study was to investigate the incidence of dysplasia in the ‘normal’ contralateral hip in patients with unilateral developmental dislocation of the hip (DDH) and to evaluate the long-term prognosis of such hips. A total of 48 patients (40 girls and eight boys) were treated for late-detected unilateral DDH between 1958 and 1962. After preliminary skin traction, closed reduction was achieved at a mean age of 17.8 months (4 to 65) in all except one patient who needed open reduction. In 25 patients early derotation femoral osteotomy of the contralateral hip had been undertaken within three years of reduction, and later surgery in ten patients. Radiographs taken during childhood and adulthood were reviewed. The mean age of the patients was 50.9 years (43 to 55) at the time of the latest radiological review. In all, eight patients (17%) developed dysplasia of the contralateral hip, defined as a centre-edge (CE) angle < 20° during childhood or at skeletal maturity. Six of these patients underwent surgery to improve cover of the femoral head; the dysplasia improved in two after varus femoral osteotomy and in two after an acetabular shelf operation. During long-term follow-up the dysplasia deteriorated to subluxation in two patients (CE angles 4° and 5°, respectively) who both developed osteoarthritis (OA), and one of these underwent total hip replacement at the age of 49 years. In conclusion, the long-term prognosis for the contralateral hip was relatively good, as OA occurred in only two hips (4%) at a mean follow-up of 50 years. Regular review of the ‘normal’ side is indicated, and corrective surgery should be undertaken in those who develop subluxation. Cite this article: Bone Joint J 2014; 96-B:1161–6


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 78 - 78
1 Mar 2009
BELTSIOS M SAVVIDOU O GIANNAKAKIS N KOUFOPOULOS G KOUVARAS J DAGAS S GRIVAS T
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PURPOSE: There is an argument in the literature regarding the use of intramedullary nail or the external fixation followed by intramedullary nail in tibial fractures with severe damage of soft tissues, threatened compartment syndrome, open type IIIA fractures and in polytrauma patients. The purpose of this retrospective study was to evaluate the results of non-jointed external fixators as a definite treatment for these type of tibial shaft fractures. MATERIAL AND METHOD: 86 patients (91 tibial shaft fractures) were treated at the authors’ institute with a non-jointed external fixator. The mean patient age was 35 years (range, 15–80). There were 70 male and 16 female patients. The average time of surgery from the accident was 10 hours. The indications for application an external fixator was: severe damage of the soft tissues in 11 fractures, an incipient compartment syndrome in 12 fractures, open type III Gustilo fractures in 57, and 11 tibia fractures in polytrauma patients. According to AO classification 46 fractures were type A, 32 type B and 13 type C. RESULTS: The average follow up was 2.9 years (ranged, 1–5 years). The average operative time was 50 min. Complications included: 3 non-unions, 5 delayed unions, 1 malunions, 1 tibia shortening, 3 superficial infections of soft tissues in open fractures, 26 pin infections and 1 osteomyelitis in open fractures. In 2 patients fat embolism was diagnosed while pulmonary embolism was a complication in 2 patients. Deep venous thrombosis (DVT) developed in 5 patients. A re-operation was performed in 11 out of 91 fractures. Change of the method was necessary in 2 out of 91 fractures. The primary callus in 10 out of 91 fractures was due to the stiffness of the unilateral non-jointed external fixators and did not influence the final results. Mean time of fracture union for the open fractures that did not require change of the method nor bone graft was 25 weeks, while for the closed fractures was 18 weeks. The dynamization of the system and partial weight bearing was started at 6 weeks and all the patients had full weight bearing by the 12th week. CONCLUSION: The unilateral external fixators were the definite treatment in 88 out of 91 fractures. The unilateral external fixators can be used as a definite treatment for tibial shaft fractures in the majority of the cases. Re-operation or change of the method is unusual and must be performed only when there is a delay in callus formation


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_III | Pages 421 - 421
1 Oct 2006
Lisai P Doria C Milia F Floris L Leali PT
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Purpose: To compare the clinical and radiographic outcomes of a unilateral transpedicular approach with those of standard bilateral transpedicular vertebroplasty. Materials and methods: Retrospective review of vertebroplasty yielded 19 vertebrae in 16 patients that were treated with a standard bilateral approach and 24 vertebrae in 21 patients who were treated with unilateral transpedicular approach. Clinical outcomes, including pain relief and change in pain medication requirements, were compared in the two groups by using chi-square test and Fisher’s exact test. Results: All patients had reported a high reduction in pain in both groups with similar clinical outcomes. Conclusions: Use of a unilateral approach in percutaneus vertebroplasty allows filling of both vertebral halves from a single puncture site with no statistically significant difference in clinical outcome from that of a bilateral transpeduncolar vertebroplasty; this technique permits a shorter operating time with lower rate of complications


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_III | Pages 385 - 385
1 Oct 2006
Colleary G McCann R Geddis C Li G Dickson G Marsh D
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Introduction: The aim of this research project was to establish a simple, reliable and repeatable externally fixed femoral fracture model. The rat was selected, as it was a suitable animal for use in a model of fracture repair and ovariectomy induced osteoporosis, both of which were to be investigated in future experiments. There are femoral fracture models described in the literature based on the insertion of an intramedullary nail prior to inducing a fracture. We felt, based on our experience of the unilateral externally fixed mouse fracture model, that external fixation would allow us to carry out radiographical and histological analysis of fracture healing without any of the tissue trauma caused by the insertion and removal of the intramedullary device. Materials and Methods: A unilateral external fixator was chosen due to its simplicity. Four threaded stainless steel pins pass through holes in an aluminium plate with nuts placed on the pin above and below the plate. The holes in the plate were 0.1mm bigger than the pins and unthreaded allowing the plate to slide freely over the pins. Tightening of the upper nut compressed the plate against the lower nut holding the pin securely. 41 female Sprague-Dawley rats, aged between 12 and 18 weeks, were used. They were anaesthetised using a standard mixture of hypnorm and midazolam and analgesia, fluids and antibiotic were administered subcutaneously prior to surgery. The femur was exposed through a lateral approach and a standardised osteotomy was made prior to the application of the fixator plate. Accurate reduction was confirmed visually at the time of surgery and also by way of a post-op x-ray. 25 animals were sacrificed at 4 days and 1, 2, 4, 6 and 8 weeks for histology. The fractured limbs were harvested, fixed, decalcified and paraffin embedded as per standard protocol and serial sections were cut. These were stained with H& E and alcian blue and analysed 15 animals were sacrificed at 4,6 or 8 weeks for biomechanical strength testing. Four-point bending was carried out on freshly harvested femurs stored in normal saline between harvest and testing. Both limbs were tested and the fractured limbs were standardised relative to the unfractured limb. Maximum load to failure was recorded and stiffness was calculated from the load-displacement curve. Results: No post-operative complications of fixation failure or infection occured. On histological assessment at D4 a predominantly lymphocytic inflammatory response was seen within the fracture haematoma. This inflammatory response was replaced with endosteal and periosteal new bone between wks 1 and 2. Bridging of the fracture gap was seen at week 6. Both stiffness and load to failure increased with increasing time. There was a statistically significant improvement in the percentage stiffness and percentage load to failure between 4 and 8 weeks (p=0.03 and p=0.018 respectively). The difference in load to failure between 6 and 8 weeks was also significantly different (p=0.042). Discussion: A simple, reliable and repeatable externally fixed rat femoral fracture model has been established


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 232 - 232
1 May 2009
Sethi A Lee S Vaidya R
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The purpose of this study was to investigate the efficacy and fusion rates of a unilateral pedicle screw construct supplemented with a translaminar screw in transforaminal lumbar interbody fusion (TLIF). The construct was used with an aim of providing suitable spine stiffness with minimal implant load for spinal fusion. Nineteen consecutive patients who underwent single level TLIF were included in the study. All patients had posterior spinal instrumentation using a unilateral pedicle screw construct with a contralateral translaminar screw. Patients were assessed preoperatively and at two, six, twelve and twenty-four weeks following surgery and at the end of one and two years. At every visit Oswestry disability index score,Visual analogue scale for pain and a pain diagram were recorded. A radiographic exam was also conducted and CT scan was done if there was concern about fusion. The average follow up was twenty-four months. There were twelve males and seven females with an average age of forty-eight years. All patients went on to clinical and radiographic union. Sixteen of nineteen patients had significant clinical improvement on VAS for pain, Oswestry scores and pain medication. Three patients had recurrence of radicular pain on the side of the TLIF leading to reexploration. In all three patients solid fusion was observed but scar tissue was evident and symptoms resolved following redecompression of the foramen. The biomechanical competence of a construct is evidenced by successful fusion. With the advent of minimally invasive techniques to achieve spinal fusion the goal is to use minimal instrumentation without compromising on the final stiffness of the spine. The construct of unilateral pedicle screws supplemented with a trans-laminar screw led to fusion in all our cases. It requires lesser soft tissue dissection and the posterior implants are 56% cheaper


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 260 - 260
1 Mar 2003
Koczewski P
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The risk of contra-lateral slip in patients with primary unilateral slipped capital femoral epiphysis (SCFE) is difficult to determine. The material consists of 115 patients operated on because of unilateral SCFE between 1968 – 1991. There were 75 boys (65%) and 40 girls (35%). The mean age at the diagnosis was 12.8 years. Methods. Measurements of such radiological parameters of hip joints as: neck-shaft angle, Alsberg angle, slip angle and Klein’s sign were done. All these measurements were done in three periods. First – at the time of admission, second – at the time of suspected contra-lateral slip and third – at follow up (minimum 2 yrs after subcapital growth plate closure). The mean follow up was 11 yrs (2 – 29). Results. Contra-lateral slip developed in 73% of patients with Alsberg angle (capital physeal – femoral shaft angle) less than 61° and only in 43% of patients with this angle bigger than 61°. No correlation between developing of contra-lateral slip and femoral neck – shaft angle, slip angle and negative Klein’s sign was found. A positive Kline’s sign in the “healthy” hip was observed in 37% of patients with unilateral SCFE at the moment of the fist slip and in all of them contra-lateral slip and/or early coxarthrosis developed. Conclusions. More vertical orientation of the proximal femoral epiphysis can be used as risk factor of the contra-lateral slip in patients with primary unilateral SCFE. Femoral neck – shaft angle, slip angle and negative Kline’s sign in the “healthy” hip have no prognostic value according to the contra-lateral slip. More than 1/3 of the patients with primary unilateral slip developed a symptomatic contra-lateral slip


The Journal of Bone & Joint Surgery British Volume
Vol. 74-B, Issue 1 | Pages 53 - 56
1 Jan 1992
Wykman A Olsson E

We studied 50 patients before and after unilateral total hip replacement, and compared them, using gait analysis, with 22 having staged bilateral operations. The average age of the patients was 65 years at the first operation. The mean follow-up was 53 months for the unilateral cases and 27 months, after the second THR, for the bilateral cases. The average interval between first and second THR was 24 months. Patients with bilateral hip disease did not gain optimal function, even on the first side, until both hips had been replaced. Unilateral replacement gave better gait analysis results than did either side after bilateral procedures


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 77 - 77
1 Jan 2018
Zhang Z Zhang H Luo D Cheng H Xiao K Hou S
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The coronal plane lower limb alignment plays an important role in the occurrence and progression in knee osteoarthritis. There have been reports of the valgus knee in patients with unilateral developmental hip dislocation (UDHD) with the relatively small sample size. Besides, few studies have analyzed the lower limb alignment of the contralateral side. The purpose of our study was to identify the coronal plane alignment of both the ipsilateral and the contralateral lower limb in patients with UDHD and find out the difference between patients with Hartofilakidis type II and III. The radiographic data of all UDHD patients who met the inclusion criteria from March 2011 to February 2017 were retrospectively reviewed, including the hip-knee-ankle angle (HKA), mechanical lateral distal femoral angle (mLDFA), anatomical lateral distal femoral angle (aLDFA), mechanical proximal tibial angle (MPTA) and the lateral distal tibial angle (LDTA). Besides, the femoral torsion angle was measured on the images of CT scan. The average HKA was 3.42°(range: −4.3–12.8°) on the affected side, and −2.11°(range: −11.4–5.4°) on the contralateral side (P?0.0001). The valgus lower limb alignment on ipsilateral side was most frequently seen in both Hartofilakidis type II (20cases, 51.3%) and type III groups (25cases, 67.6%), whereas for the contralateral side, the neutral alignment in type II group (27 cases, 69.2%) and varus alignment in type III group (19 cases, 51.4%) were most commonly observed. Both the mLDFA (P?0.001) and aLDFA (P?0.001) of ipsilateral side were significantly smaller than those of contralateral side. The average femoral torsion angle was 37.9°(range: 10.4–64.4°) on the affected side, and 27.1°(range: 9.7–45.5°) on the contralateral side (P?0.001). In conclusion, UDHD patients may present with lower limb malalignment on both sides. The valgus lower limb alignment is the most common deformity on ipsilateral side, which is caused by increased femoral torsion angle as well as the decreased aLDFA. The patients with Hartofilakidis type III UDHD may be more prone to present varus alignment deformity than those with Hartofilakidis type II on the contralateral side. The lower limb malalignment and deformity of ipsilateral distal femur should be considered during any surgery involving hip, knee or femur


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 1 | Pages 153 - 154
1 Jan 2010
Siau K Singh A Awon K Kelly A Chester JF

Rupture of an aneurysm of the common iliac artery is a rare cause of pain in the hip. We describe an elderly hypertensive patient with an aneurysmal rupture of the left common iliac artery who presented with unilateral hip pain masquerading as septic arthritis


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_6 | Pages 32 - 32
1 Jul 2020
Perelgut M Teeter M Lanting B Vasarhelyi E
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Increasing pressure to use rapid recovery care pathways when treating patients undergoing total hip arthroplasty (THA) is evident in current health care systems for numerous reasons. Patient autonomy and health care economics has challenged the ability of THA implants to maintain functional integrity before achieving bony union. Although collared stems have been shown to provide improved axial stability, it is unclear if this stability correlates with activity levels or results in improved early function to patients compared to collarless stems. This study aims to examine the role of implant design on patient activity and implant fixation. The early follow-up period was examined as the majority of variation between implants is expected during this time-frame. Patients (n=100) with unilateral hip OA who were undergoing primary THA surgery were recruited pre-operatively to participate in this prospective randomized controlled trial. All patients were randomized to receive either a collared (n=50) or collarless (n=50) cementless femoral stem. Patients will be seen at nine appointments (pre-operative, < 2 4 hours post-operation, two-, four-, six-weeks, three-, six-months, one-, and two-years). Patients completed an instrumented timed up-and-go (TUG) test using wearable sensors at each visit, excluding the day of their surgery. Participants logged their steps using Fitbit activity trackers and a seven-day average prior to each visit was recorded. Patients also underwent supine radiostereometric analysis (RSA) imaging < 2 4 hours post-operation prior to leaving the hospital, and at all follow-up appointments. Nineteen collared stem patients and 20 collarless stem patients have been assessed. There were no demographic differences between groups. From < 2 4 hours to two weeks the collared implant subsided 0.90 ± 1.20 mm and the collarless implant subsided 3.32 ± 3.10 mm (p=0.014). From two weeks to three months the collared implant subsided 0.65 ± 1.54 mm and the collarless implant subsided 0.45 ± 0.52 mm (p=0.673). Subsidence following two weeks was lower than prior to two weeks in the collarless group (p=0.02) but not different in the collared group. Step count was reduced at two weeks compared to pre-operatively by 4078 ± 2959 steps for collared patients and 4282 ± 3187 steps for collarless patients (p=0.872). Step count increased from two weeks to three months by 6652 ± 4822 steps for collared patients and 4557 ± 2636 steps for collarless patients (p=0.289). TUG test time was increased at two weeks compared to pre-operatively by 4.71 ± 5.13 s for collared patients and 6.54 ± 10.18 s for collarless patients (p=0.551). TUG test time decreased from two weeks to three months by 7.21 ± 5.56 s for collared patients and 8.38 ± 7.20 s for collarless patients (p=0.685). There was no correlation between subsidence and step count or TUG test time. Collared implants subsided less in the first two weeks compared to collarless implants but subsequent subsidence after two weeks was not significantly different. The presence of a collar on the stem did not affect patient activity and function and these factors were not correlated to subsidence, suggesting that initial fixation is instead primarily related to implant design


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 49 - 49
1 Jan 2003
Nakamura H Konishi S Seki M Yamano Y
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Posterior approach to the lumbar spine necessarily induces structural damage of paravertebral muscles. In order to avoid these changes, we have started to utilize a microscopic decompression of the spinal canal via an unilateral approach since 1998. The purpose of this study was to evaluate the results of this operative procedure for lumbar spinal canal stenosis. A total of 18 patients, 13 men and five women, were reviewed. The age at the time of surgery ranged from 53years to 78years with a mean of 69.0years. Follow up period averaged 12.3months ranging from one to 32months. As for operative procedure, unilateral paravertebral muscle was retracted laterally and lam-inotomy in the approached side was performed. Following complete decompression of a nerve root in the approached side, microscope was tilted and the inner aspect of lamina in the contralateral side was resected using high-speed drill with a guard of yellow ligament to dural sac and nerve root. Following the procedure, yellow ligament was resected and nerve root in the contralateral side was decompressed. Results: In operation time, blood loss and recovery rate of JOA score, there were no statistical differences compared with ordinal laminotomy cases. Dural sac was well decompressed not only in the hemilaminec-tomy side but also in the contralateral side. All cases showed intensity change of paravertebral muscle in the approached side on T2 weighted MRI. Conclusion: The procedure described here was definitely effective because paravertebral muscle in the contralateral side and midline structure of the lumbar spine could be completely preserved


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 220 - 220
1 May 2006
Corner JA Marshall R
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Bilateral decompression of spinal stenosis may induce instability which compromises outcome. In an attempt to overcome this problem, bilateral decompression can be carried out through a unilateral approach. The ipsilateral side is decompressed by hemi-laminectomy with undercutting partial facetectomy and the contra-lateral side is treated by careful excavation beneath the spinous processes and laminae with preservation of the laminae, posterior ligament complexes and paraspinal muscles. This is achieved with the aid of an operating microscope or loupe and headlight. Previous reports contain little information about outcome and complications. We reviewed 30 patients with bilateral spinal stenosis, but without significant spondylolisthesis who were decompressed bilaterally from a unilateral approach by a single surgeon during a calendar year. They represented a third of our annual operations for spinal stenosis. Thirty patients had 45 levels decompressed. Female to male ratio was 2:1 and average age was 66 years. The average duration of preoperative symptoms was 1.6 years. The mean follow up period was 30 weeks (12 weeks to one year). Assessment was carried out using the Oswestry Disability Index, pre- and post-operative visual analogue pain scores for leg pain and back pain, walking distance and MacNab criteria of patient outcome. Results: improvement in Oswestry Disability Index, pain scores for sciatica and back pain and improved walking distance. All but one case had good or excellent outcome. Complications: one dural tear and two cases with temporary dermatomal sensory change. Whilst the technique is safe, and effective, a longer randomised controlled study is needed to demonstrate any real advantage over traditional approaches


The purpose this prospective, randomized clinical trial was to determine if unilateral or bilateral simultaneous total hip arthroplasty procedures resulted in a differing incidence of fat embolization, degree of hemodynamic compromise, levels of hypoxemia or mental status changes. Also, the incidence of fat embolization was compared between the cemented and cementless total hip arthroplasty in the patients with a unilateral- and bilateral simultaneous total hip arthroplasty. One hundred and fifty-six consecutive patients undergoing primary total hip arthroplasty were enrolled prospectively in the study after giving informed consent. The group consisted of fifty patients undergoing bilateral simultaneous total hip arthroplasty and 106 patients undergoing unilateral total hip arthroplasty. One hundred and three hips were cemented and 103 hips were cementless. To determine the hemodynamic changes and to detect the fat and bone marrow embolization, arterial and right atrial blood samples were obtained before implantation (baseline) and at one, three, five and ten minutes after implantation of the acetabular component. Also, arterial and right atrial blood samples were obtained at one, three, five and ten minutes after implantation of the femoral component. And then blood samples were obtained at twenty-four and forty-eight hours after the operation. Arterial blood pressure, right atrial pressure, arterial oxygen tension and carbon-dioxide tension were monitored at corresponding times. The presence of lipid was determined with oil red O fat stain and the presence of cellular contents of bone marrow was determined with Wright-Giemsa stain. The incidence of fat embolism was not statistically different (P=1.000) between the patients with a bilateral total hip arthroplasty (twenty seven patients or 54 per cent) and the patients with a unilateral total hip arthroplasty (fifty-two patients or 49 per cent). In the semiquantitative analysis of fat globules in both groups, there was no tendency to have a higher number of fat globules in the bilateral group than in the unilateral group. Also, the incidence of bone marrow embolization was not statistically different (P=0.800) between the patients with a bilateral total hip arthroplasty (eight patients or 16 per cent) and the patients with a unilateral total hip arthroplasty (fourteen patients or 13 per cent). There was no statistical difference (P=0.800) in the incidence of the presence of fat globule between the cemented total hip (thirty-four patients or 34 per cent) and the cementless total hip arthroplasty (forty-seven patients or 44 per cent). Also, there was no statistical difference (P=0.627) in the incidence of the presence of bone marrow cells between the cemented total hip arthroplasty (thirteen patients or 13 per cent) and the cement-less total hip arthroplasty (twelve patients or 11 per cent). Four patients with positive bone marrow cells had neurological manifestation. All of these four patients developed diffuse encephalopathy with confusion and agitation for about twenty-four hours. The present study confirmed that the incidence of fat and bone marrow embolization is similar in the patients with a bilateral simultaneous-and unilateral total hip arthroplasty as well as in the patients with cemented and cementless total hip arthroplasty. The patients with bone marrow cell emboli had a significantly lower arterial oxygen tension (p=0.022) and oxygen saturation (p=0.017) than the patients without bone marrow cell emboli. On the contrary, the number of fat globules did not affect the perioperative hemodynamic changes. Encephalopathy is related to the biochemical and/or mechanical changes by bone marrow cells


The Bone & Joint Journal
Vol. 96-B, Issue 10 | Pages 1419 - 1423
1 Oct 2014
Kaneko H Kitoh H Mishima K Matsushita M Kadono I Ishiguro N Hattori T

Salter innominate osteotomy is an effective reconstructive procedure for the treatment of developmental dysplasia of the hip (DDH), but some children have a poor outcome at skeletal maturity. In order to investigate factors associated with an unfavourable outcome, we assessed the development of the contralateral hip. We retrospectively reviewed 46 patients who underwent a unilateral Salter osteotomy at between five and seven years of age, with a mean follow-up of 10.3 years (7 to 20). The patients were divided into three groups according to the centre–edge angle (CEA) of the contralateral hip at skeletal maturity: normal (> 25°, 22 patients), borderline (20° to 25°, 17 patients) and dysplastic (<  20°, 7 patients). The CEA of the affected hip was measured pre-operatively, at eight to nine years of age, at 11 to 12 years of age and at skeletal maturity. The CEA of the affected hip was significantly smaller in the borderline and dysplastic groups at 11 and 12 years of age (p = 0.012) and at skeletal maturity (p = 0.017) than in the normal group. Severin group III was seen in two (11.8%) and four hips (57.1%) of the borderline and dysplastic groups, respectively (p < 0.001). . Limited individual development of the acetabulum was associated with an unfavourable outcome following Salter osteotomy. Cite this article: Bone Joint J 2014;96-B:1419–23


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_13 | Pages 7 - 7
1 Mar 2013
Worsley P Whatling G Holt C Bolland B Barrett D Stokes M Taylor M
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The aim of this study was to perform a comprehensive evaluation of the changes in function from pre- to post-surgery in total and unilateral knee arthroplasty (UKA/TKA) patients. Twenty healthy (age 62.4 ±5.9, 11 male), 14 UKA (age 60.9 ±10.1, 8 male) and 17 TKA (age 67.2 ±8.1, 9 male) patients were studied. KA patients were assessed four weeks pre- and six months post-operation. Measures of perceived pain and function were collected using Oxford Knee Score (OKS) questionnaire. Tests of objective function included joint range of motion (RoM), ultrasound imaging, and 3-D motion analysis/inverse modelling from gait and sit-stand. An optimal set of variables was used to classify KA function using the Cardiff DST method. Pre-KA and healthy individuals were accurately classified (96%). Post-operation questionnaire measures of function improved for both UKA and TKA groups. However, observed measures of RoM, muscle atrophy and gait had only limited gains. This resulted in 57% of UKA and only 27% of TKA patients being classified as healthy post-operation. The results of this study show that 6 months post-surgery UKA patients had higher function than TKA. Using statistical approaches to combine functional assessments has provided an accurate platform to classify function and estimate changes from pre- to post-surgery. The clinical application of this tool requires further investigation and comparison to commonly used clinical techniques


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_I | Pages - 84
1 Mar 2002
Lukhele M
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The success of lumbar spine fusion depends on good patient selection and bone grafting technique. Instrumentation of the fusion, now popular, improves fusion rates, eliminates the need for postoperative braces and allows early mobilisation. However, the stress shielding caused by rigid internal fixation is thought to lead to osteopoenia and degeneration of adjacent segments. Theatre times, intra-operative complications and costs are increased when pedicle screw fixation is added. This is a report of a pilot study of eight patients who had one-level fusion and unilateral instrumentation between 1998 and 2000. Theatre time, fusion rate and functional outcomes were evaluated. The minimum follow-up time was eight months. Fusion was achieved in all patients and there was no metal failure. One patient continued to have back and leg pain in spite of a solid fusion. Although this is a small study undertaken over a short period, the results suggest that unilateral pedicle screw fixation can be safely undertaken


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 592 - 593
1 Oct 2010
Aksahin E Bicimoglu A Celebi L Hasan HM Yavuzer G Yuksel H
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Aim: Surgical treatment for idiopathic clubfeet aims to realign the foot and allow plantigrade weight bearing with adequate joint motion. In spite of satisfying clinical and radiological results for both the physician and the parents shortly after the operation, deterioration may occur years after the surgery. The aim of this study was to evaluate gait characteristics of children with surgically treated unilateral clubfoot and had good clinical outcome. Methods: Twelve children (mean age 5.9±2.3 years (4–9)) with surgically treated unilateral clubfoot before age one and twelve age matched healthy children were included in the study. Foot length, calf circumference, ankle range of motion and radiographic measurements were recorded. Quantitative gait data was collected with the Vicon 370 (Oxford Metrics, Oxford, UK). Two force plates (Bertec, Colombus, Ohio, USA) were used for kinetic analysis. All time-distance (walking velocity, cadence, step time, step length, double support time), kinematic (joint rotation angles of pelvis, hip, knee and ankle in sagittal, coronal and transverse planes) and kinetic (ground reaction forces, moments and powers of hip, knee and ankle) data were processed using Vicon Clinical Manager software package. Results: Foot length of the operated side was shorter than the unaffected side but the difference was not significant (p> 0.05). Calf circumference and ankle range of motion were significantly less than the unaffected side (p< 0.05). Quantitative gait data revealed that children with clubfoot had slower walking velocity (0.75±0.25 versus 1.02±0.18 m/sec, p=0.001), shorter stride length (0.72±0.23 versus 0.91±0.05 meters, p=0.001) and less ankle plantar flexor moment (0.73±0.22 versus 0.88±0.11 m/sec, p=0.007) than healthy children. Unaffected side showed increased pelvic excursions and medio-lateral ground reaction forces as well as decreased ankle and hip motion in sagittal plane. Conclusion: We detect various deviations in gait parameters even in so called well treated patients according to radiological and clinical criteria. Alterations in the unaffected foot may be the result of the subclinical involvement of the unaffected foot by disease as well as the compensatory mechanisms. These gait deviations may lead long-term morbidity later in adulthood


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 190 - 190
1 Mar 2003
Bagnall K Rajwani T Bhargava R Moreau M Raso J Mahood J Elander A
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Introduction: Although there are several known causes of scoliosis, most are of unknown cause and develop during adolescence, making adolescent idiopathic scoliosis (AIS) the most common form. It has long been hypothesised that unilateral closure of the neurocentral junction accompanied by continued growth on the opposite side could lead to vertebral rotation and subsequent lateral curvature. However, autopsy studies of neurocentral junction closure in children has revealed that these joints close at approximately six years of age consequently excluding this hypothesis as a cause of AIS. In contrast, a recent MRI study has suggested that in some children at least, the NCJ does not close until much later in development around the time of puberty thereby resurrecting this hypothesis as a potential cause of AIS. This study was designed to investigate closure time and pattern of closure of the NCJ in normal patients to determine whether further examination of this hypothesis might be warranted. Methods and results: The morphology of the NCJs in 20 patients between the ages of 3 and 15 were observed in MR images taken for purposes other than spinal anomaly. The structure of individual NCJs were observed and reconstructed in 3-dimensions. The age at which NCJs became closed was determined and pattern of closure of a typical NCJ was created using the reconstructed images. The pattern of closure of the NCJs along the vertebral column was also determined and any differences between right and left sides at the same level was also noted. The results showed that there was a sequence of closure along the vertebral column for the NCJs with those in the cervical and lumbar regions being the first to close and those at the approximate level of T8 being the last to close. While the NCJs in the cervical and lumbar regions close at 5–6 years of age, those in the thoracic region, that are the last to close, do so at approximately 12 years of age. No significant difference between the stage of closure of the left and right sides was seen at any level. Conclusion: The results of this study have shown that the closure of the NCJs in those vertebrae that form at approximately the most common level for the apical vertebra associated with AIS (midthoracic) does not occur until the time of puberty. This contrasts sharply with previously held views on the age of closure. Although no significant difference in closure between left and right sides was seen among these particular patients it does not exclude unilateral closure as a cause of AIS at least in some patients. These results suggest that examination of this hypothesis should be resurrected and that further study is well warranted. MR examination of young patients with small, initial curves could be well worthwhile


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_16 | Pages 42 - 42
1 Oct 2014
Maratt J Esposito C McLawhorn A Carroll K Jerabek S Mayman D
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Sagittal pelvic tilt (PT) has been shown to effect the functional position of acetabular components in patients with total hip replacements (THR). This change in functional component position may have clinical implications including increased likelihood of wear or dislocation. Surgeons can use computer-assisted navigation intraoperatively to account for a patient's pelvic tilt and to adjust the position of the acetabular component. However, the accuracy of this technique has been questioned due to the concern that PT may change after THR. The purpose of this study was to measure the change in PT after THR, and to determine if preoperative clinical and radiographic parameters can predict PT changes after THR. 138 consecutive patients who underwent unilateral THR by one surgeon received standing bi-planar lumbar spine and lower extremity radiographs preoperatively and six weeks postoperatively. Patients with prior contralateral THR, conversion THR and instrumented lumbosacral fusions were excluded. PT and pelvic incidence (PI) were measured preoperatively for each patient, and PT was measured on the postoperative imaging. A negative value for PT indicated posterior pelvic tilt. Patient demographics were collected from the chart. Average age was 56.8±10.9 years, average BMI was 28.3±6.0 kg/m2, and 67 patients (48.6%) were female. Mean preoperative pelvic tilt was 0.6°±7.3° (range: −19.0° to 17.9°). We found greater than 10° of sagittal PT in 23 out of 138 (16.6%) patients in this sample. Mean post-operative pelvic tilt was 0.3°±7.4° (range: −18.4° to 15.0°). Mean change in pelvic tilt was −0.3°±3.6° (range: −9.6° to 13.5°). PT changed by less than 5° in 119 of 138 patients (86.2%). The mean difference in pre-operative and post-operative PT is not statistically significant (p = 0.395). Pre-operative PT was strongly correlated with post-operative PT (r2 = 0.88, p = 0.0001) (Figure 1). There was not a statistically significant relationship between PI and change in PT (r2 = −0.16, p = 0.06). In conclusion, based on the variability in pelvic tilt in this study population and the relatively small change in pelvic tilt following THA tilt-adjustment of the acetabular component position based on standing pre-operative imaging is likely to be of benefit in the majority of patients undergoing navigated THA. However, we have been unable to predict the relatively rare occurrence of a large change in pelvic tilt, which would confound tilt-adjusted component position


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_4 | Pages 103 - 103
1 Feb 2017
Layne C Amador R Pourmoghaddam A Kreuzer S
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Hip arthroplasty is commonly used as the final treatment approach for patients experiencing end-stage osteoarthritis. The number of these patients needing this treatment is expected to grow significantly by year 2030 to more than 572000 patients [Kurtz et al., 2007]. One of the important outcomes of hip arthroplasty is to improve patients' functions postoperatively. The evaluation of walking can provide a wealth of information regarding the efficiency of this treatment in improving a patient's mobility. Assessing the kinematic features of gait collected with a motion capture system combined with the aid of a motor-driven treadmill provides the advantage of enabling the evaluator to collect precise information about a large number of strides in a short period of time. Body segment kinematics (i.e. joint motion) are most often represented in the form of time series data with the abscissa (X axis) representing time and the ordinate (y axis) representing the motion of a particular joint. Although a great deal of information can be gained from the analyses of time series data, non-linear analyses tools can provide an additional and important dimension to a clinician's assessment of gait recovery. In this study eight patients (4 females, mean age 64.9, SD 11.1) have currently been assessed after unilateral hip arthroplasty. All surgeries were conducted by direct anterior approach by using two different approaches; three of the patients were treated by bone preservation technique and received Minihip short stem implant (Corin Ltd., Cirencester, UK) and five were treated by using a press fit stem implant Accolade II (Stryker, Mahwah, NJ USA). Patients performed a single three-minute trial of walking on a motor-driven treadmill at a self-selected pace. Using a 12 camera system, bilateral lower limb joint motion was collected prior to the surgery, at three and six weeks and at three and 6 months after the surgery. Depending upon the patient's preferred walking pace; between 40 and 45 strides were collected during each trial. Kinematic data obtained from force plates embedded in the treadmill were used to identify the heel strike and toe off events for each stride. After time normalizing the each of the joint angles (i.e. hip, knee, ankle) for each stride to 100 data points the data were then amplitude normalized to the initial point of the pre-surgery data. The non-linear tools of angle-angle and phase plane were used to explore relationships that are not readily apparent with linear wave form analyses. Angle-angle diagrams between a variety of joints angles both within a single limb or bilaterally enabled us to explore segmental coordination patterns and how they changed over the six months after surgery. Phase plane analyses included comparing joint motion relative to the velocity of that motion. This technique provided insights into the nature of the control of the joint. The additional information that results from the use of non-linear analyses provides an additional dimension of that can aide the clinician in understanding the recovery curve. This additional insight can be used to guide therapeutic decision making


The Journal of Bone & Joint Surgery British Volume
Vol. 69-B, Issue 2 | Pages 243 - 250
1 Mar 1987
Ippolito E Tudisco C Farsetti P

We have attempted to identify the most important long-term prognostic factors in Perthes' disease by studying 61 patients affected unilaterally. The average age at diagnosis was 7 years 5 months and at follow-up it was 32 years, an average interval of 25 years. The age at diagnosis, age at follow-up, Catterall group, acetabular coverage, femoral head subluxation and the other head-at-risk signs were statistically correlated with Stulberg, Cooperman and Wallensten (1981) radiographic classes and the Iowa hip score. Statistically significant correlations were found between Stulberg class and Iowa hip score; age at diagnosis and Stulberg class; age at follow-up and Iowa hip score; and between lateral subluxation of the femoral head and Iowa hip score. Three age-groups of patients were found to carry different long-term prognoses. Those below five years of age at diagnosis showed a statistically significant correlation between Catterall group and Stulberg Classes I and II. Patients between five and nine years of age at diagnosis showed a significant correlation between Catterall group and Stulberg Classes I, II, III and IV while in patients diagnosed after nine years of age there was no statistical correlation between Catterall group and Stulberg class, all having a poor prognosis and ending up in Stulberg Classes III, IV and V


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 215 - 216
1 May 2011
Lichte P Kobbe P Pardini D Giannoudis P Pape H
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Background: Polytrauma patients with bilateral femur shaft fractures are known to have a higher rate of complications when compared with those who have sustained unilateral fractures. The current study tests the hypothesis that the high incidence of posttraumatic complications in patients who have no severe head or chest injury is caused by accompanying injuries rather than by the additional femur fracture. Methods: Prospective cohort study. Inclusion criteria: Injury severity score > 16 points; No AIS score value of the head or chest > 3 points. Two study groups: a unilateral (group USF) (n=146) and a bilateral femur shaft fracture (group BSF) (n=29). A further differentiation was made according to the patient’s status. All patients underwent early (< 24 hours after injury) fixation of their extremity fractures. Endpoints monitored were: Pneumonia, Acute lung injury (ALI), Systemic inflammatory response syndrome (SIRS), Sepsis. Statistics: Pearson chi-square test for binary indicators of injury severity, regression analyses regarding clinical complications. Results: Patients with bilateral femur fractures exhibited a longer ICU stay (p< 0.01), a higher incidence of pneumonia (p< 0.02) and SIRS (p=0.04) than those with unilateral fractures. Following corrective analyses for injury severity, no differences in blood transfusion rates, length of ICU stay, or complications was observed. Patients in borderline condition spend significantly more time in the ICU in comparison to those in stable condition. For analyses predicting presence of systemic inflammatory response syndrome, only the variable indicating receipt of a blood transfusion upon admission to the hospital emerged as a significant predictor. Bilateral fracture patients who were in uncertain condition preoperatively, developed significantly more complications postoperatively(p=0.02). Conclusions: Polytrauma patients with bilateral femur shaft fractures have a similar clinical course as those with unilateral fractures when no significant head or chest injury is present. An increased incidence of systemic inflammatory response syndrome was associated with three variables: presence of borderline condition, hemothorax and requirement of blood transfusion. This may have important treatment implications, including the management of major fractures


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 68 - 68
1 Mar 2012
Willett K Al-Khateeb H Kotnis R Bouamra O Lecky F
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Background. To determine the relative contributions of bilateral versus unilateral femoral shaft fracture plus injuries in other body regions to mortality after injury. Study design. A retrospective analysis of the prospectively recorded Trauma Registry data (TARN) from 1989 to 2003. Methods. Patients were divided into groups UFi (isolated unilateral femur injury),BFi (isolated bilateral femur injury) and UFa and BFa if an associated injury was present. Data collected for each patient included age, Injury Severity Scores, Glasgow Coma Scale, mortality, physiological parameters, the timing and extent of prehospital care, the time to arrival at the hospital, initial treatments, time to and type of surgery, length of ICU and hospital stay. Logistic regression data analysis was performed to determine variables that were associated with increased mortality. Results. Patients in group BFa had a significantly higher ISS (23 vs 9),reduced GCS (12 vs 15) and increased mortality rate (31.6% vs 9.8%) than patients in group BFi. Group BFa patients had an increased number of associated injuries than group UFa. Regression analysis of variables evident on admission revealed a significant correlation between bilateral femoral fractures with associated injuries and mortality. However bilateral fracture, even in isolation significantly increased the odds of mortality by 3.07(1.36-6.92). Intramedullary nailing (IMN) was the method of fracture fixation associated with the lowest patient mortality overall. However, when assessing patient mortality in the BFa group with an ISS of more than 40, three other fracture fixation regimens were associated with a lower mortality rate than the IMN group. Conclusions. The increase in mortality with bilateral femoral fractures is more closely associated with the presence of associated injuries and poor physiological parameters than to the presence of the bilateral femoral fracture alone. However contrary to ISS scoring the latter does convey a significant additional risk of mortality. The presence of bilateral femoral fractures should alert the clinician to the very high likelihood (80%) of significant associated injuries in other body systems and their life-threatening potential


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 304 - 305
1 Jul 2011
Baker P Dowen D Mcmurtry I
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Introduction: The recent UK national comparative audit of the use of blood in primary, elective, unilateral THR found that 25% of patients required a peri-operative transfusion. We felt this figure was higher than should be expected, especially of surgeons with a dedicated arthroplasty subspecialty. We therefore audited our own practice with particular emphasis on the relationship between surgeon volume, implant and the need for transfusion. Methods: A retrospective review of 508 consecutive primary, elective, unilateral hip and knee arthroplasties performed over a 12 month period. Pre- and post- operative haemoglobin levels, need for transfusion, and the timing and volume of any transfusion were recorded for each patient. Analysis determined the overall rate of transfusion, the details of any such transfusion, and the effects of surgeon volume upon the transfusion rate. Results: The transfusion rate following THR (10%) was significantly lower than those found in the national audit. The transfusion rate following TKR was 7%. Multivariate analysis demonstrated that surgeon volume (< 50 THRs/yr Vs > 50 THRs/yr) and a preop-erative Hb < 12g/dl were the only significant determinants of a need for post operative transfusion (Both p< 0.05) following both THR and TKR. Other variables (age, gender, anaesthetic type, ASA, indication, surgeon grade and experience, implant, approach) were not significant. A preoperative haemoglobin of < 12g/dl was associated with a 6 fold and 3 fold increased risk of needing a transfusion following hip and knee replacement respectively. Discussion: The need for allogenic blood transfusion following primary arthroplasty is influenced by both patient and surgeon related factors. Surgeons who have a dedicated arthroplasty practice and perform a high volume of procedures have significantly lower transfusion rates when compared to nationally accepted figures. This has implications for both patient care and resource management


The Journal of Bone & Joint Surgery British Volume
Vol. 49-B, Issue 2 | Pages 249 - 257
1 May 1967
Braakman R Vinken PJ

Bilateral interlocking of the articular facets of the cervical spinal column results from excessive flexion. Unilateral interlocking (hemiluxation) results from simultaneous excessive flexion and rotation. Patients with hemiluxation of the cervical spine often have only mild complaints and the clinical signs may be slight. The diagnosis is made radiologically, but it is often overlooked. Various forms of treatment may give good results. In recent hemiluxation, reduction is advisable to promote recovery of radicular symptoms. The effect of reduction on spinal cord symptoms is uncertain. Manual reduction under general anaesthesia is usually successful, with the possible exception of some cases of interlocking at C.6-C.7, or C.7-T.1. Skull traction with weights of 5 to 10 kilograms even when prolonged is hardly ever successful; with weights of 10 kilograms or more there is a chance of success. Surgical reduction is not always necessary. A hemiluxation of more than two weeks' standing may still be reduced but non-operative methods offer little chance of success. In this series there has been no aggravation of the neurological deficit after reduction. Although hemiluxation shows a tendency to spontaneous stabilisation it is wise in our opinion to apply some form of fixation. The selection of the method of fixation depends on the neurological picture and on the estimated degree of instability. The latter depends on the presence or absence of additional damage to the interlocked and adjacent vertebrae. Manual reduction by means of traction in the longitudinal axis of the cervical spine under general anaesthesia with muscle relaxation, followed by immobilisation in a plaster jacket (Minerva type) for three months is successful in many cases. If surgical stabilisation is considered necessary an attempt at manual reduction should be made before operation so that when the patient is placed on the table the cervical spinal canal has regained its normal shape. In general, sufficient stability will have been achieved after approximately three months, so that for hemiluxations of more than three months duration surgical treatment will only rarely be necessary. Figure 11 shows the methods of treatment that we advise


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 539 - 539
1 Aug 2008
Kumar V Malhotra R Bhan S
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Background: Joint replacements are being performed on ever younger patients at a time when average expectancy of life is continuing to rise. Any reduction in the strength and mass of periprosthetic bone could threaten the longevity of implant by predisposing to loosening and migration of prosthesis, periprosthetic fracture and problems in revision arthroplasty. Aims & Objectives: This study aims to analyse the femoral periprosthetic stress-shielding following unilateral cementless total hip replacement using DEXA scan by quantifying the changes in bone mineral density around femoral component over a period of one year and identify the factors influencing the bone loss. Material & Method: Femoral periprosthetic bone mineral density was measured in the seven Gruen Zones with DEXA scan at 2 weeks, 3 months and 1 year after surgery in 20 patients who had undergone unilateral cementless total hip replacement, of which 10 patients had been implanted with 4/5. th. porous coated CoCr stems and other 10 patients with 1/3. rd. porous coated titanium alloy stems. Results: At both 3 months and one year postoperatively, bone loss due to stress-shielding was seen in both stems with maximum loss in zone VII and minimum in zone III, IV, V. The maximum mean percentage bone mineral density loss in 4/5. th. porous coated CoCr stems in zone VII was 16.03% at 3 month and 22.42% at 1 year as compared to loss of 10.07% and 16.01% in 1/3. rd. porous coated Ti alloy stems. Increased bone loss was seen in patients who had larger diameter stem (> 13.0 mm) and in patients with low bone mineral density in the unoperated hip. Conclusion: Bone loss as a result of stress-shielding is more pronounced in 4/5. th. porous coated CoCr stems as compared to 1/3. rd. porous coated titanium alloy stems


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXI | Pages 10 - 10
1 Jul 2012
Subramanian AS Tsirikos AI
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Purpose of the study. To compare the effectiveness of unilateral and bilateral pedicle screw techniques in correcting adolescent idiopathic scoliosis. Summary of Background Data. Pedicle screw constructs have been extensively used in the treatment of adolescent patients with idiopathic scoliosis. It has been suggested that greater implant density may achieve better deformity correction. However, this can increase the neurological risk related to pedicle screw placement, prolong surgical time and blood loss and result in higher instrumentation cost. Methods. We reviewed the medical notes and radiographs of 139 consecutive adolescent patients with idiopathic scoliosis (128 female-11 male, prospectively collected single surgeon's series). We measured the scoliosis, thoracic kyphosis (T5-T12), and lumbar lordosis (L1-L5) before and after surgery, as well as at minimum 2-year follow-up. SRS 22 data was available for all patients. Results. All patients underwent posterior spinal arthrodesis using pedicle screw constructs. Mean age at surgery was 14.5 years. We had 2 separate groups: in Group 1 (43 patients) correction was performed over 2 rods using bilateral segmental pedicle screws; in Group 2 (96 patients) correction was performed over 1 rod using unilateral segmental pedicle screws with the 2. nd. rod providing stability of the construct through 2-level screw fixation both proximal and distal. Group 1. Mean Cobb angle before surgery for upper thoracic curves was 37°. This was corrected by 71% to mean 11° (p<0.001). Mean Cobb angle before surgery for main thoracic curves was 65°. This was corrected by 71% to mean 20° (p<0.001). Mean Cobb angle before surgery for thoracolumbar/lumbar curves was 60°. This was corrected by 74% to mean 16° (p<0.001). No patient lost >2° correction at follow-up. Mean preoperative thoracic kyphosis was 24° and lumbar lordosis 52°. Mean postoperative thoracic kyphosis was 21° and lumbar lordosis 50° (p>0.05). Mean theatre time was 5.5 hours, hospital stay 8.2 days and intraoperative blood loss 0.6 blood volumes. Complications: 1 transient IOM loss/no neurological deficit; 1 deep wound infection leading to non-union and requiring revision surgery; 1 rod trimming due to prominent upper end. Mean preoperative SRS 22 score was 3.9; this improved to 4.5 at follow-up (p<0.001). Pain and self-image demonstrated significant improvement (p=0.001, p<0.001 respectively) with mean satisfaction rate 4.9. Group 2. Mean Cobb angle before surgery for upper thoracic curves was 42°. This was corrected by 52% to mean 20° (p<0.001). Mean Cobb angle before surgery for main thoracic curves was 62°. This was corrected by 70% to mean 19° (p<0.001). Mean Cobb angle before surgery for thoracolumbar/lumbar curves was 57°. This was corrected by 72% to mean 16° (p<0.001). No patient lost >2° correction at follow-up. Preoperative scoliosis size for all types of curves correlated with increased surgical time (r=0.6, 0.4). Mean preoperative thoracic kyphosis was 28° and lumbar lordosis 46°. Mean postoperative thoracic kyphosis was 25° and lumbar lordosis 45° (p>0.05). Mean theatre time was 4.2 hours, hospital stay 8.4 days and intraoperative blood loss 0.4 blood volumes. Complications: 1 deep and 1 superficial wound infections treated with debridement; 1 transient brachial plexus neurapraxia; 1 SMA syndrome. Mean preoperative SRS 22 score was 3.7; this improved to 4.5 at follow-up (p<0.001). Pain, function, self-image and mental health demonstrated significant improvement (p<0.001 for all parameters) with mean satisfaction rate 4.8. Comparison between groups showed no significant difference in regard to age at surgery, preoperative and postoperative scoliosis angle for main thoracic and thoracolumbar/lumbar curves, as well as SRS scores and length of hospital stay. Better correction of upper thoracic curves was achieved in Group 1 (p<0.05), but upper thoracic curves in Group 2 were statistically more severe before surgery (p<0.05). Increased surgical time and blood loss was recorded in Group 1 (p<0.05, p=0.05 respectively). The implant cost was reduced by mean 35% in Group 2 due to lesser number of pedicle screws. Conclusion. Unilateral and bilateral pedicle screw instrumentation has achieved excellent deformity correction in adolescent patients with idiopathic scoliosis, which was maintained at follow-up. This has been associated with high patient satisfaction and low complication rates. The unilateral technique using segmental pedicle screw correction has reduced surgical time, intraoperative blood loss and implant cost without compromising surgical outcome for the most common thoracic and thoracolumbar/lumbar curves. The bilateral technique achieved better correction of upper thoracic scoliosis


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_2 | Pages 74 - 74
10 Feb 2023
Genel F Pavlovic N Lewin A Mittal R Huang A Penm J Patanwala A Brady B Adie S Harris I Naylor J
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In the Unites States, approximately 24% of people undergoing primary total knee or total hip arthroplasty (TKA, THA) are chronic opioid users pre-operatively. Few studies have examined the incidence of opioid use prior to TKA/THA and whether it predicts outcomes post-surgery in the Australian context. The aim was to determine: (i) the proportion of TKA and THA patients who use opioids regularly (daily) pre-surgery; (ii) if opioid use pre-surgery predicts (a) complication and readmission rates to 6-months post-surgery, (b) patient-reported outcomes to 6-months post-surgery.

A retrospective cohort study was undertaken utilising linked individual patient-level data from two independent databases comprising approximately 3500 people. Patients had surgery between January 2013 and June 2018, inclusive at Fairfield and Bowral Hospitals.

Following data linkage, analysis was completed on 1185 study participants (64% female, 69% TKA, mean age 67 (9.9)). 30% were using regular opioids pre-operatively. Unadjusted analyses resulted in the following rates in those who were vs were not using opioids pre-operatively (respectively); acute adverse events (39.1% vs 38.6%), acute significant adverse events (5.3% vs 5.7%), late adverse events: (6.9% vs 6.6%), total significant adverse events: (12.5% vs 12.4%), discharge to inpatient rehab (86.4% vs 88.6%), length of hospital stay (5.9 (3.0) vs 5.6 (3.0) days), 6-month post-op Oxford Score (38.8 (8.9) vs 39.5 (7.9)), 6 months post-op EQ-VAS (71.7 (20.2) vs 76.7 (18.2), p<0.001), success post-op described as “much better” (80.2% vs 81.3%).

Adjusted regression analyses controlling for multiple co-variates indicated no significant association between pre-op opioid use and adverse events/patient-reported outcomes.

Pre-operative opioid use was high amongst this Australian arthroplasty cohort and was not associated with increased risk of adverse events post-operatively. Further research is needed in assessing the relationship between the amount of pre-op opioid use and the risk of post-operative adverse events.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 311 - 311
1 May 2010
Savaridas T Brenkel I Ballantyne J
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Introduction: Total Hip Replacement (THR) is an effective procedure that improves Quality of Life (QoL) in patients with hip arthritis. Co-existing back pain is common in these patients. We assessed the impact of back pain on the medium term outcomes of patients undergoing unilateral THR using a disease specific measure, Harris Hip Score (HHS) and a general health questionnaire, Short Form-36 Health Evaluation (SF-36). The SF-36 generates scores on 8 dimensions of QoL; physical functioning (PF), role limitation due to physical problems (RP), role limitation due to emotional problems (RE), social functioning (SF), mental health (MH), energy/vitality (EV), bodily pain (Pain) and general health perception (GHP). It also contains an item requesting information on perceived health change over the past year (CH). Methods: Between 4th January 1998 and 22nd July 2001, 909 consecutive patients undergoing unilateral THR were entered into a regional arthroplasty database. An audit nurse collected data prospectively. Patients were assessed pre-operatively and demographic details recorded. Patients were asked specifically about the presence or not of back pain. Post-operative follow up was at 6 mnths, 18 mnths, 3 yrs and 5 yrs. At each point the HHS and SF-36 were measured. There were more females in our study population (61.2% v 38.8%). Statistical analysis was performed for males and females after adjusting for age, body mass index and pre -op scores. Results: Pre-op, mean HHS and SF-36 score were lower for patients with back pain. Post-THR, patients had overall better outcome scores. Male patients with back pain had significantly lower (P< 0.01) post-THR outcome scores at all time points for HHS, PF, SF and Pain compared to their male peers without back pain. These changes persisted to 5 yrs. This effect was not demonstrated in female patients. The only exception was in the Pain domain of SF-36 where female patients with back pain had lower scores (P< 0.01) than those without back pain. Conclusion: Patients with back pain obtain significant benefit from unilateral THR in the medium term and this is maintained at 5 yrs. Despite the clinical benefit to the group as a whole, the absolute scores for males with pre-op back pain remain significantly lower than their peers without back pain. Pre-op back pain did not significantly affect outcome in females


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_I | Pages 45 - 45
1 Mar 2005
Hannah H Gaston M Brenkel I
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Introduction: Previous studies have suggested that bilateral total hip replacement (THR) is a safe and economically advantageous procedure. It has not become routine practice in many centres due to persisting concerns about complications and the patients’ ability to rehabilitate. In this study we compare one group of patients who underwent bilateral THR with another group who had only a unilateral procedure despite osteoarthritis in both hips. They were assessed for complications and functional outcome. Methods: All data collected prospectively between 1998 and 2002. All patients had osteoarthritis and were recruited during the same time period . Group A comprised 49 patients who were listed for bilateral THR. Group B consisted of 215 patients listed for unilateral THR, with both hips symptomatic. Pain and function were assessed using the Harris Hip Score preoperatively and at 6 months post operatively. All intra and postoperative complications were recorded. Results: There was no statistical difference between the groups for sex , pathology, body mass index or American Society of Anaesthetists (ASA) scores. There is a difference in age between the two groups with the bilateral group being younger (p< 0.01). Although group A had a higher death rate, it was not statistically significant. The deep infection and revision rate was similar for both groups. The average length of stay for group A was 13 days compared to 8 days for group B.There was a significant difference in the likelihood of blood transfusion with a transfusion rate of 78% in group A and 22% in group B (p< 0.001). Conclusion: This study has demonstrated no significant increased risk of death, deep infection or need for revision with bilateral hip replacements. The increased likelihood of blood transfusion should be offset against the definite economic advantages and the good early outcome from performing bilateral total hip replacements


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Anterior cruciate ligament deficiency (ACLD) affects the performance of walking in some patients (non-copers) while copers are able to minimize the effects via proper musculoskeletal compensations. Since many daily activities are more challenging than level walking, e.g., obstacle-crossing, it is not clear whether copers are able to cope with such a challenging task. A successful and safe obstacle-crossing requires not only sufficient foot clearance of the swing limb, but also the stability of the body provided mainly by the stance limb. Failure to meet these demands may lead to falls owing to loss of balance or tripping over obstacles. The purpose of the current study was to identify the motor deficits and/or biomechanical strategies in coper and non-coper ACLD patients when crossing obstacles of different heights for a better function assessment. Ten coper and ten non-coper ACLD patients were recruited in the current study. The non-coper ACLD subjects were those who had not been able to return to their pre-injury level activities, had at least once giving way during the last six months and their Lysholm knee scale was less than 70 [1]. Each subject walked and crossed obstacles of heights of 10%, 20% and 30% of their leg lengths at a self-selected pace. Kinematic and kinetic data were measured with a 7-camera motion analysis system (Vicon, Oxford Metrics, U.K.) and two force plates (AMTI, U.S.A.). The leading and trailing toe clearances were calculated as the vertical distances between the toe markers and the obstacle when the toe was directly above the obstacle. Joint angles of both limbs, and joint moments of the stance limb, were calculated. Peak extensor moments at the knee during stance phase and the corresponding joint angles were extracted for statistical analysis. A 3 by 2, 2-way mixed-model analysis of variance with one between-subject factor (group) and one within-subject factor (obstacle height) was performed (α=0.05). SAS version 9.2 was used for all statistical analysis. Compared with the copers, significantly reduced leading and trailing toe clearances were found in the non-coper group (P<0.05). The non-copers showed significantly decreased peak extensor moments (P<0.05) and flexion angle at the affected knee during the stance phase before leading limb crossing (P<0.05). Distinctive gait patterns were identified in coper and non-coper patients with unilateral anterior cruciate ligament deficiency during obstacle crossing. During the stance phase before the un-affected leading limb crossing, the non-copers showed significantly reduced flexion and peak extensor moments at the affected knee (i.e., quadriceps avoidance), primarily owing to the impaired stability at the affected knee. The significantly reduced leading and trailing toe clearances in the non-coper group indicate that the non-coper ACLD patients are at a higher risk of tripping over the obstacle, and may have difficulty in regaining balance owing to the unstable ACLD knee. Advanced rehabilitation program or reconstruction of the ACL is suggested for the non-coper group


To present the results of surgical correction in patients with double or triple thoracic/lumbar AIS (Lenke types 2,3,4) with the use of a novel convex/convex unilateral segmental screw correction technique in a single surgeon's prospective series. We reviewed the medical records and spinal radiographs of 92 consecutive patients (72 female-20 male). We measured scoliosis, thoracic kyphosis, lumbar lordosis, scoliosis flexibility and correction index, coronal and sagittal balance before and after surgery, as well as at minimum 2-year follow-up. SRS-22 data was available preoperatively, 6-month, 12-month and 2-year postoperatively for all patients. Surgical technique. All patients underwent posterior spinal fusion using pedicle screw constructs. Unilateral screws were placed across the convexity of each individual thoracic or lumbar curve to allow for segmental correction. ‘Corrective rod’ was the one attached to the convexity of each curve with the correction performed across the main thoracic scoliosis always before the lumbar. Maximum correction of main thoracic curves was always performed, whereas the lumbar scoliosis was corrected to the degree required to achieve a balanced effect across the thoracic and lumbar segments and adequate global coronal spinal balance. Concave screws were not placed across any deformity levels. Bilateral screws across 2 levels caudally and 1–2 levels cephalad provided proximal/distal stability of the construct. Mean age at surgery was 14.9 years with mean Risser grade 2.8. The distribution of scoliosis was: Lenke type 2–26 patients; type 3–43 patients; type 4–23 patients. Mean preoperative Cobb angle for upper thoracic curves was 45°. This was corrected by 62% to mean 17° (p<0.001). Mean preoperative Cobb angle for main thoracic curves was 70°. This was corrected by 69% to mean 22° (p<0.001). Mean preoperative Cobb angle for lumbar curves was 56°. This was corrected by 68% to mean 18° (p<0.001). No patient lost >2° correction at follow-up. Mean preoperative thoracic kyphosis was 34° and lumbar lordosis 46°. Mean postoperative thoracic kyphosis was 45° (p<0.001) and lumbar lordosis 46.5° (p=0.69). Mean preoperative coronal imbalance was 1.2 cm. This corrected to mean 0.02 cm at follow-up (p<0.001). Mean preoperative sagittal imbalance was −2 cm. This corrected to mean −0.1 cm at follow-up (p<0.001). Mean theatre time was 187 minutes, hospital stay 6.8 days and intraoperative blood loss 0.29 blood volumes (1100 ml). Intraoperative spinal cord monitoring was performed recording cortical and cervical SSEPs and transcranial upper/lower limb MEPs and there were no problems. None of the patients developed neurological complications, infection or detected non-union and none required revision surgery to address residual or recurrent deformity. Mean preoperative SRS-22 score was 3.6; this improved to 4.6 at follow-up (p<0.001). All individual parameters also demonstrated significant improvement (p<0.001) with mean satisfaction rate at 2-year follow-up 4.9. The convex-convex unilateral pedicle screw technique can reduce the risk of neurological injury during major deformity surgery as it does not require placement of screws across the deformed apical concave pedicles which are in close proximity to the spinal cord. Despite the use of a lesser number of pedicle fixation points compared to the bilateral segmental screw techniques, in our series it has achieved satisfactory scoliosis correction and restoration of global coronal and sagittal balance with improved thoracic kyphosis and preserved lumbar lordosis. These results have been associated with excellent patient satisfaction and functional outcomes as demonstrated through the SRS-22 scores


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 280 - 280
1 Sep 2005
Murray A Brenkel I
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Previous studies have suggested that bilateral TKR is a safe and economically advantageous procedure. However, because of persistent concerns about complications and patients’ ability to rehabilitate, it has not yet become routine practice. Using data from the Scottish Arthroplasty Project, which has centrally collated data gathered prospectively between 1989 and 1999, we analysed 19 247 patients who underwent primary knee replacement. Any subsequent admission for TKR was noted. Deaths following an index procedure were identified from the General Register of Deaths. In 30% of patients a contralateral TKR was done within 5 years. The overall hospital stay for both unilateral and bilateral TKR has been comparable since 1993. The mortality rate following simultaneous bilateral TKR (1%) is similar to that following unilateral TKR (1.2%). Only 25% of Scottish Surgeons perform simultaneous bilateral TKR. However, bilateral knee arthritis is common and bilateral TKR carries no significantly increased cumulative risk of death, deep infection or need for revision. The increased likelihood of blood transfusion should be offset against the definite advantages of one anaesthetic, a reduced hospital stay and good early outcome


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 102 - 102
1 Mar 2009
Doets H Vergouw D Veeger H Houdijk H
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The purpose of this study was to investigate the energy cost of walking after total ankle arthroplasty (TAA), and to investigate if possible differences could be attributed to changes in external mechanical work required for the step-to-step transition. Eleven patients, 6 months to 4 years after successful unilateral TAA, and 11 healthy controls walked on a treadmill at a self-selected speed (SWS) and a fixed walking speed (FWS, 1.25 m/s). Ground reaction forces and oxygen uptake were measured. External mechanical work was analyzed using the double inverted pendulum model. At SWS, velocity in the TAA group was reduced (v=1.29 vs 1.42 m/s, p=0.05) but metabolic energy cost was not different (E=2.50 vs 2.24 J/kg/m, p=0.32). At FWS, metabolic energy cost in the TAA patients was significantly higher (E=2.58 vs 1.96 J/kg/m, p=0.003). The difference in metabolic energy cost at FWS coincided with an increased negative work in the leading leg and reduced positive work in the trailing leg with TAA during double support. Although this indicates that the mechanical work for the step-to-step transition increases, the total external mechanical work over a complete stride was not different between the TAA and the control group. TAA patients walk at a higher metabolic energy cost. This cannot be explained by differences in external mechanical work. Other factors, such as changes in muscle function, should be taken into account


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 104 - 104
1 Feb 2003
Hill RMF Brenkel I
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Although drains date back to the Hippocratic era, their routine use remains controversial in total hip arthroplasty. The literature suggests that they can provide a retrograde route for infection as well as decreasing the organism count required to develop an infection. The use of drains has not decreased the size of wound haematomas at day five on ultrasound or the incidence of massive wound haematomas. Neither have they been shown to significantly decrease wound infections. This consecutive prospective randomised study was designed to evaluate what role drains have in the management of patients undergoing hip arthroplasty. A total of 577 patients undergoing unilateral or bilateral hip arthroplasty were evaluated in a randomised prospective trial of drain versus no drain, between September 1997 and December 2000. All patients had a standardised pre, inter and post operative regime and were independently assessed using the Harris hip score and SF36 pre-operatively, at discharge and at six months post surgery. The superficial and deep infection rate of 6. 4% and 0. 4% was seen in those drained and 7. 1% and 0. 7% in the non-drained group. Only one patient sustained a clinical haematoma that did not requiring drainage or transfusion in the non-drain group. The transfusion rate in those drained was 33. 0% compared to 26. 4% in those not drained. There was no statistical advantage in using a drain P> 0. 05 regarding these variables or in the length of stay, SF36 or Harris hip scores at pre-op and six months. Using a drain did significantly increase the likelihood of requiring a transfusion P< 0. 05. In conclusion drains provide no statistical advantage whilst represent an additional cost and expose hip arthroplasty patients to an unacceptable risk of infection and transfusion


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 467 - 467
1 Sep 2009
Butt U Burston B Kamathia G Gleeson R
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Introduction: Total knee replacement commonly results in postoperative requirement of blood transfusion. Allogeneic blood transfusion carries transfusion related risks, continuing effort to reduce allogeneic blood transfusion is important. The purpose of this study was to asses the economic justification of the use of an autologous blood transfusion after total knee replacement and to determine whether it reduces allogeneic blood transfusion and length of postoperative hospital stay. Patients and Methods: Retrospectively, 149 patients undergoing primary unilateral total knee replacement using vacuum drain were selected. Demographics, pre and postoperative haemoglobin were recorded. Need for allogeneic blood and postoperative hospital stay were also recorded. Results: 8% (n12) received allogeneic blood. The average amounts received were 2 units. Mean length of stay in those received allogeneic blood were (n12) 8.1 days. Mean length of hospital stay in those not transfused (n137) were 5.5 days (p< 0.05). The cost of allogeneic blood per patient £29.31. Total cost of retansfusion system per patients £60.8. Excess bed occupancy in those transfused £55.21. The cost saving for employing a retransfuion system (55.21+29.31)−60.8 = £24.44 per patient. Conclusion: Employing autologous retransfusion system is effective method of reducing allogeneic blood requirement. Retransfusion system will reduce in hospital stay to the level seen patients not transfused. There would be a significant economic benefit in utilising such system in district general hospitals


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 287 - 288
1 May 2010
Weil L Weil L Weil W Cain J Fridman R
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Many studies have evaluated bilateral versus unilateral surgery in large joints, however, limited research is available to compare outcomes of bilateral-staged foot surgeries versus synchronous-bilateral foot surgery. 186 consecutive cases of first metatarsophalangeal joint surgery were prospectively included in this study; 252 procedures were performed: 120 were unilateral or staged-bilateral, and 66 were synchronous-bilateral operations. Patients were evaluated at 6–and 12-weeks for specific early complications, and surveyed about there return to work, activities of daily living, shoe gear requirements, satisfaction, and reasons for choosing staged or synchronous surgery. Additionally, a cost analysis was performed on all surgical scenarios. Student-t test showed no statistical significance between groups in all clinical settings to a 95% confidence level. Complication rates were similar and few in all situations. Patients were very satisfied when choosing bilateral-synchronous surgery and would elect to repeat it the same way 97% of the time. The economic costs to the health system average 25% greater when patients undergoing first metatarsophalangeal joint surgery have the procedure performed one foot at a time. Combined with the time lost from work, this reveals a significant economic cost to both society and patient


The Bone & Joint Journal
Vol. 95-B, Issue 2 | Pages 224 - 229
1 Feb 2013
Bennett PM Sargeant ID Midwinter MJ Penn-Barwell JG

This is a case series of prospectively gathered data characterising the injuries, surgical treatment and outcomes of consecutive British service personnel who underwent a unilateral lower limb amputation following combat injury. Patients with primary, unilateral loss of the lower limb sustained between March 2004 and March 2010 were identified from the United Kingdom Military Trauma Registry. Patients were asked to complete a Short-Form (SF)-36 questionnaire. A total of 48 patients were identified: 21 had a trans-tibial amputation, nine had a knee disarticulation and 18 had an amputation at the trans-femoral level. The median New Injury Severity Score was 24 (mean 27.4 (9 to 75)) and the median number of procedures per residual limb was 4 (mean 5 (2 to 11)). Minimum two-year SF-36 scores were completed by 39 patients (81%) at a mean follow-up of 40 months (25 to 75). The physical component of the SF-36 varied significantly between different levels of amputation (p = 0.01). Mental component scores did not vary between amputation levels (p = 0.114). Pain (p = 0.332), use of prosthesis (p = 0.503), rate of re-admission (p = 0.228) and mobility (p = 0.087) did not vary between amputation levels.

These findings illustrate the significant impact of these injuries and the considerable surgical burden associated with their treatment. Quality of life is improved with a longer residual limb, and these results support surgical attempts to maximise residual limb length.

Cite this article: Bone Joint J 2013;95-B:224–9.


The Bone & Joint Journal
Vol. 97-B, Issue 11 | Pages 1577 - 1581
1 Nov 2015
Balci HI Kocaoglu M Sen C Eralp L Batibay SG Bilsel K

A retrospective study was performed in 18 patients with achondroplasia, who underwent bilateral humeral lengthening between 2001 and 2013, using monorail external fixators. The mean age was ten years (six to 15) and the mean follow-up was 40 months (12 to 104).

The mean disabilities of the arm, shoulder and hand (DASH) score fell from 32.3 (20 to 40) pre-operatively to 9.4 (6 to 14) post-operatively (p = 0.037). A mean lengthening of 60% (40% to 95%) was required to reach the goal of independent perineal hygiene. One patient developed early consolidation, and fractures occurred in the regenerate bone of four humeri in three patients. There were three transient radial nerve palsies.

Humeral lengthening increases the independence of people with achondroplasia and is not just a cosmetic procedure.

Cite this article: Bone Joint J 2015;97-B:1577–81.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 338 - 338
1 May 2010
Yilmaz S Yuksel H Ersoz M Aksahin E Muratli H Celebi L Bicimoglu A
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Aim: Patients treated with one-stage combined operations after walking age for developmental dysplasia of the hip (DDH), and whose follow-up revealed both clinical and radiological complete healing underwent flexor and extensor isokinetic muscle strength (IMS) measurements of the hip and results were evaluated in comparison with the contralateral hips. Methods: A total of 22 patients with unilateral DDH and treated with one-stage combined operations after walking age were included in the study. All patients were operated by the same surgeon. In their last follow-up visit, all patients were functionally excellent in accordance with the Barrett’s Modified McKay Criteria and according to the Severin’s Classification for radiological grading of the hip all cases were type I. IMS of hip flexors and extensors were tested by Biodex 3 Pro isokinetic test device at 120º/sc and 240º/sc. In all patients, peak torque (PT), peak torque angle (PTA), total work (TW), and average power (AP) values of operated and non-operated hips were measured at both angular velocities and recorded separately for flexors and extensors. For comparative evaluation, values of the operated and non-operated hips were used for determining the differences in IMS (DIMS), total work (DTW), and average power (DAP). In statistical assessment; Student’s t test, paired t test, and Spearman’s Rank correlation analysis were used. Results: The mean age of patients were 12,8±2,9 (9–18) years old. At the last control visit, the mean value of follow-up periods were 112,6±32,0 (68–159) months. Parameters like age, age at the time of operation, and the length of postoperative follow-up period showed no statistical relation with IMS measurements (p> 0,05). For flexors, TW was lower at the operated hip when compared with the non-operated hip at 120º/sc and 240º/sc (p=0,001 and p=0,002, respectively). AP was lower at the operated hip at 120º/sc and 240º/sc (p=0,011 and p=0,003, respectively). PT was lower at the operated hip (22,5±11,3) when compared with the non-operated hip (27,1±12,1) only at 120º/sc (p=0,001). For extensor muscles, PT, TW, AP, and PTA showed no statistically significant difference (p> 0,05). For flexors, the DIMS between operated and non-operated hips at 120º/sc and 240º/sc were measured as −15,3±22,2% (median;-14,4) and −8,0±21,4% (median;−2,5), respectively. Conclusions: In operated DDH patients with a mean follow-up period of around 10 years, IMS measurements revealed that the flexor muscle strength of the operated hip was still weaker than the non-operated hip. At 120º/sc, which represented evaluation against higher resistance, DIMS, DWF, and DAP were higher when compared with 240º/sc. This finding shows that hip flexors of these patients may remain weak in activities like sports, which require more resistance


The Journal of Bone & Joint Surgery British Volume
Vol. 76-B, Issue 4 | Pages 563 - 567
1 Jul 1994
Jerre R Billing L Hansson G Wallin J

We reviewed, at an average age of 46 years, a series of 61 patients treated for unilateral slipped upper femoral epiphysis. At maturity there had been slipping of the contralateral hip in 11 patients (18%) and another 14 (23%) had originally had evidence of bilateral slipping when the primary radiographs were reviewed. In only two of these 25 patients (8%) was the slipping of the contralateral hip symptomatic. The incidence of early osteoarthritis of the contralateral hip was 7 of 36 with no slip, 5 of 16 with an untreated slip and 1 of 9 with a slip pinned in situ. If all 61 contralateral hips had been prophylactically pinned at the primary admission, 36 of the operations (59%) would have been unnecessary. We recommend that prophylactic pinning of the contralateral hip should not be standard, but that lateral radiography by the Billing technique be repeated every third to fourth month until closure of the growth plate begins. Hips in which a slip occurs should be pinned in situ


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 408 - 408
1 Jul 2010
Rashid M Squires R Khaleel A
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Aims: To compare rates of blood transfusion post knee arthroplasties for patients treated with and without tranexamic acid (TA) and assess for any haemoglobin change perioperatively between the groups. Methods: This retrospective observational study included 207 patients undergoing primary unilateral knee replacement surgery who were divided by administration of TA intraoperatively (n=120) or without (n=87). The TA group was further subdivided into patients undergoing a standardised autogenic retransfusion procedure (n= 86) and those without (n=44). Case notes and laboratory results were used to study pre and post operative haemoglobin, administration of TA and blood products. The exclusion criteria consisted of patients in ASA classes III & IV, revision surgery, and patients undergoing bilateral or unicompartmental knee replacements. Analysis of haemoglobin change was undertaken using the student t-test. Significance was concluded when p < 0.05. Results: The average haemoglobin drop in the TA group (without auto-transfusion) was 1.96g/dL versus 1.8g/dL in the no drug group which was not significant (p= 0.459). The average drop in the TA group (with auto-transfusion) was 1.78g/dL, also not significant (p=0.922). 3 of the 44 patients (7%) from the TA group (without auto-transfusion) required blood transfusions compared against 7 of the 87 non tranexamic acid group (8%) which was not significant. Conclusion: There was no significant difference between all three groups. This study raises questions over the efficacy of TA treatment as a means to reduce perioperative blood loss in total knee replacements. Further, TA does not reduce blood loss and transfusion requirements even when autogenic retransfusion was used


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 338 - 338
1 May 2010
Yuksel H Yilmaz S Duran S Aksahin E Muratli H Celebi L Bicimoglu A
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Aim: Complete tenotomy was performed on the most important flexor hip muscle; namely the iliopsoas during open reduction in patients with developmental dysplasia of the hip (DDH). The iliopsoas and other flexor-extensor muscles in operated and contralateral hips were evaluated comparatively by magnetic resonance imaging (MRI). Methods: A total of 22 patients with unilateral DDH after the walking age and treated with one-stage combined surgery were analyzed. All patients were operated by the same surgeon with complete tenotomy of iliopsoas muscle hindering open reduction. All patients had functionally excellent results in accordance with the Barrett’s Modified McKay Criteria in their last follow-up visits and according to Severin’s classification all cases were type 1. The imaging was performed by 1,5 T GE Excite MRI device at the supine position, without contrast material and sedation. The sagittal sections for iliopsoas muscle and T2-W FSE axial images for flexor and extensor muscle groups were used. The operated and contralateral sides were compared. Student’s t test, paired t test, and Spearman’s Rank correlation analysis were used for statistical assessment. Results: The mean age was 12,8±2,9 (9–18) years old. The mean postoperative follow-up period was 112,6 ± 32,0 (68–159) months. The reattachment of the iliopsoas to trochanter minor was observed in 7 patients, with no significance in terms of age, postoperative follow-up period, and the duration of postoperative period (p> 0,05). The atrophy in the operated side was significant in the length of iliopsoas muscle section area (p=0,0001); and the section areas of rectus femoris (p=0,002), tensor fascia lata (p=0,0001), and gluteus maximus (p=0,0001). No significance was detected in sartorius muscle section area (p=0,886). However, unlike other muscles; the ratio of operated versus contralateral side mean muscle section areas was above 1 (1,1± 0,3) for the sartorius muscle. Iliopsoas muscle reattachment was not significant for ratios of the other muscles’ operated versus contralateral side muscle section areas (p> 0,05). The atrophy was significant for the second (p=0,03) and the third (p=0,022) section’s diameter ratios in the non-reattachment versus reattachment group for the iliopsoas muscle. Conclusion: The reattachment of the iliopsoas muscle to trochanter minor after complete tenotomy was observed in 32% of patients. Following complete iliopsoas tenotomy, the expected compensatory hypertrophy in other flexor hip muscles was not detected. At the operated side, all evaluated muscles were atrophic except for the sartorius muscle. The atrophy of iliopsoas muscle was significant for the operated hip with non-reattachment to insertion site versus reattachment group


The Journal of Bone & Joint Surgery British Volume
Vol. 55-B, Issue 4 | Pages 742 - 745
1 Nov 1973
Pugh LGCE

1. The relation of oxygen intake and walking speed has been investigated in a sixty-two-year-old patient before and after unilateral hip replacement for osteoarthritis. 2. Before operation walking speed was reduced to three to five kilometres per hour and stride length to 73 centimetres. Oxygen intake was 0·9-l·2 litres per minute and net energy cost 49 kilocalories per kilometre. 3. Nine months after operation the patient could walk at up to 8 kilometres per hour with a stride of 115 centimetres, oxygen intake of 2·4 litres per minute and net energy cost of 34 kilocalories per kilometre. Most of this improvement took place within three months of operation. 4. The oxygen intake of walking at ordinary speeds after full recovery was comparable with that of control subjects aged twenty-seven to twenty-nine years. In very fast walking, however, the oxygen intake was higher than that of the controls, whose oxygen intake was 1·95 litres per minute at 8 kilometres per hour. 5. The use of a stick or crutches did not reduce the oxygen intake in slow walking. However, crutches enabled the subject to walk at over 8 kilometres per hour with oxygen intake of 2·4 litres per minute (85 per cent of maximum oxygen intake)


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 5 | Pages 596 - 602
1 May 2012
Hansson G Nathorst-Westfelt J

In the majority of patients with slipped upper femoral epiphysis only one hip is involved at primary diagnosis. However, the contralateral hip often becomes involved over time. There are no reliable factors predicting a contralateral slip. Whether or not the contralateral hip should undergo prophylactic fixation is a matter of controversy. We present a number of essential points that have to be considered both when choosing to fix the contralateral hip prophylactically as well as when refraining from surgery and instead following the patients with repeat radiographs.


The Journal of Bone & Joint Surgery British Volume
Vol. 69-B, Issue 2 | Pages 339 - 340
1 Mar 1987
Matthews M


The Journal of Bone & Joint Surgery British Volume
Vol. 45-B, Issue 4 | Pages 637 - 651
1 Nov 1963
Roaf R

Severe kypho-scoliosis, lateral curvature and lordo-scoliosis are ultimately caused by disturbance of vertebral growth. The results of treatment by destroying the growth potential opposite the area of growth inhibition have been encouraging. When the operation has been adequate further deterioration has been prevented; in younger children there has been improvement with further growth. It is important that the growth arrest should be at the right site and that it should be sufficiently extensive. Accurate pre-operative diagnosis of the type and extent of the curve is important.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_15 | Pages 152 - 152
1 Mar 2013
Vijaysegaran P Banic G Whitehouse S Crawford R
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There has been much discussion and controversy in the media recently regarding metal toxicity following large head metal on metal (MoM) total hip replacement (THR). Patients have been reported as having hugely elevated levels of metal ions with, at times, devastating systemic, neurolgical and/or orthopaedic sequelae.

However, no direct correlation between metal ion level and severity of metallosis has yet been defined. Normative levels of metal ions in well functioning, non Cobalt-Chrome hips have also not been defined to date.

The Exeter total hip replacement contains no Cobalt-Chrome (Co-Cr) as it is made entirely from stainless steel. However, small levels of these metals may be present in the modular head of the prosthesis, and their effect on metal ion levels in the well functioning patient has not been investigated.

We proposed to define the “normal” levels of metal ions detected by blood test in 20 well functioning patients at a minimum 1 year post primary Exeter total hip replacement, where the patient had had only one joint replaced.

Presently, accepted normal levels of blood Chromium are 10–100 nmol/L and plasma Cobalt are 0–20 nmol/L. The UK Modern Humanities Research Association (MHRA) has suggested that levels of either Cobalt or Chromium above 7 ppb (equivalent to 135 nmol/L for Chromium and 120 nmol/L for Cobalt) may be significant. Below this level it is indicated that significant soft tissue reaction and tissue damage is less likely and the risk of implant failure is reduced.

Hips were a mixture of cemented and hybrid procedures performed by two experienced orthopaedic consultants. Seventy percent were female, with a mixture of head sizes used.

In our cohort, there were no cases where the blood Chromium levels were above the normal range, and in more than 70% of cases, levels were below recordable levels. There were also no cases of elevated plasma Cobalt levels, and in 35% of cases, levels were negligible.

We conclude that the implantation with an Exeter total hip replacement does not lead to elevation of blood metal ion levels.


The Journal of Bone & Joint Surgery British Volume
Vol. 73-B, Issue 3 | Pages 523 - 524
1 May 1991
Miller R Menelaus M


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 11 - 12
1 Mar 2010
Sculco TP Memtsoudis SG Valle AGD Besculides MC Gaber L
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Purpose: To determine mortality and morbidity for bilateral total knee replacment compared to unilateral knee replacement and revision total knee replacement using the National National Hospital Discharge Survey to include large numbers of patients and look at outcomes. Method: We analyzed nationally representative data to elucidate the demographics, comorbidities, hospital stay, in-hospital complications and mortality of patients undergoing BTKA and compared them with those of patients undergoing UTKA and revision TKA (RTKA). Data in the National Hospital Discharge Survey on hospital discharges with procedure codes for BTKA, UTKA and RTKA between 1990 and 2004 was analyzed. The demographics, comorbidities, in-hospital stay, complications and mortality were studied. We identified 4,169,489 discharges (153,259 BTKAs; 3,677,161 UTKAs; and 339,069 RTKAs). Results: Patients undergoing BTKA were younger (1.5 years) and had a lower prevalence of comorbidities for hypertension (vs. UTKA), diabetes, lung disease, and coronary artery disease (vs. UTKA and RTKA). The length of hospitalization was 5.8 days for BTKA, 5.28 for UTKA, and 5.41 for RTKA. Despite similar length of hospitalization, the prevalence of procedure related complications was higher for BTKA (14.17%+/−0.76 (SE)) than for UTKA (9.01%+/−0.17) and RTKA (9.84%+/−0.57). In hospital mortality was highest for BTKA patients (BTKA: 0.47%+/−0.15%; UTKA: 0.30%+/−0.03; RTKA: 0.27%+/−0.09). Conclusion: Despite younger age and lower comorbidity burden, patients undergoing BTKA had an approximately 1.6 times higher rate of procedure related complications and mortality compared to those undergoing UTKA. Outcomes for RTKA patients for most variables were similar to those for UTKA. In a multivariate analysis, BTKA, advanced age and male gender were independent risk factors for complications and mortality following TKA surgery


The Journal of Bone & Joint Surgery British Volume
Vol. 62-B, Issue 1 | Pages 31 - 36
1 Feb 1980
Harrison M Blakemore M

The radiographs of 153 children suffering from Perthes' disease of one hip were studied to examine the bony outline of the femoral capital epiphysis in the unaffected hip. In 48.4 per cent of patients irregularity of the surface, flattening or dimpling, were noted; in the majority of instances (37.2 per cent) these changes were present in the initial anteroposterior radiograph. By contrast, these changes were present in only 10.4 per cent of a control series of 153 children in whom intravenous urography was being performed, these children being matched for age and sex with the children with Perthes' disease. A second unmatched control series of 49 children whose pelves were being radiographed after injury showed a 6.1 per cent incidence of contour irregularities in 98 femoral capital epiphyses. In the patients with Perthes' disease and in the control series obtained at urography the incidence of changes was inversely related to age. The possible cause and significance of contour irregularities in normal children and in those with Perthes' disease is disscussed.


The Journal of Bone & Joint Surgery British Volume
Vol. 51-B, Issue 2 | Pages 348 - 353
1 May 1969
McCarthy DM Dorr CA MacKintosh CE

1. A woman of seventy-four presenting with gigantism of the left hand and foot, lipomatosis, progressive arthropathy and psoriasis is described.

2. The associations of the various conditions are examined in the light of the previously reported cases and the differential diagnosis of this condition (macrodystrophia lipomatosa) from other causes of localised gigantism is discussed.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_11 | Pages 15 - 15
1 Jun 2016
Withers TM Lister S Sackley C Clark A Smith T
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Introduction

Previous systematic reviews have shown that patients experience low physical activity levels following total hip replacement (THR). However no previous systematic reviews have examined the changes between pre- and post-operative physical activity levels.

Methods

AMED, MEDLINE, EMBASE, CENTRAL, CINHAL, openSIGLE, ClinicalTrials.gov and UK Clinical Trials Gateway databases were searched to 19th May 2015. All study designs presenting data on physical activity at pre- and up to one-year post-operatively were included. Eligible studies were critically appraised using the Cochrane risk of bias tool (for randomised controlled trials (RCTs)) and the CASP tool (non-RCTs). Where possible, mean differences (MD) and 95% confidence intervals (CI) were calculated through meta-analyses.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 2 - 2
1 Jan 2011
Thomason K Van Der Walt P
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Orthopaedic surgery accounts for about 10% of red cell transfusions used in hospital. In view of the recognized risks and decreasing availability of donor blood, every effort should be made to minimize inappropriate transfusions.

Methods: Data was collected on the number of patients prescribed blood transfusion after primary total hip and knee replacement at the North Devon District Hospital. It involved 211 patients in 2004, 599 patients in 2005 and 812 patients in ‘06/’07. The effect of withdrawing the use of drains and instigating local infiltration of the wound with diluted adrenaline on transfusion rates was monitored and the results compared against the national average.

Results: The transfusion rates for hip arthroplasty came down from 15.2% in 2004 to 8.8% in 2007 and for knee arthroplasty from 12.2% in 1004 to 5.3% in 2007.

Conclusion: Our current transfusion rates are well below the national average, without the use of cell savers. We wish to discuss the factors which might affect transfusion rates and share our experience after introducing a simple, inexpensive, safe and effective post-operative blood transfusion policy. The respective contributions of drains and infiltration will be emphasized.


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 9 | Pages 1178 - 1182
1 Sep 2011
Davis AM Wood AM Keenan ACM Brenkel IJ Ballantyne JA

Studies describing the effect of body mass index (BMI) on the outcome of total hip replacement have been inconclusive and contradictory. We examined the effect of BMI on medium-term outcome in a cohort of 1617 patients who underwent a primary total hip replacement for osteoarthritis. These patients were followed prospectively for five years with the outcomes of dislocation, revision, duration of surgery and deep and superficial infection studied, as well as collecting Harris hip scores (HHS) and Short-Form 36 (SF-36) questionnaires pre-operatively and at review. A multivariate analysis was performed to see whether BMI is an independent predictor of poor outcome.

We found that patients with a BMI of ? 35 kg/m2 have a 4.42 times higher rate of dislocation than those with a BMI < 25 kg/m2. Increasing BMI is also associated with superficial infection and poorer HHS and SF-36 scores at five years. These trends remain significant even when multivariate analysis adjusts for age, gender, prosthesis, operating consultant, pre-operative HHS and SF-36, and comorbidities including diabetes mellitus, cardiac disease and osteoporosis.

Despite the increased risks, the five-year outcome scores indicate that obese patients have much to gain from total hip replacement. Thus total hip replacement should not be withheld from patients solely on the grounds of an elevated BMI. However, longer-term follow-up of this cohort is required to establish whether adverse outcomes become more evident with time.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 157 - 157
1 Jul 2002
Waters T Bentley G
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The purpose of this study was to evaluate the role of patellar resurfacing in total knee replacement surgery. We reviewed 48 patients who had undergone bilateral knee replacement with patellar resurfacing on only one side. Follow-up was from 18 months to 9.5 years and the patients were assessed using the Knee Society rating, a clinical anterior knee pain score and BOA patient satisfaction score. Patients were also asked specifically if they had a preference for either knee. Assessment was performed without knowing which patella had been resurfaced.

52.1% of patients favoured the resurfaced knee, 8% the unresurfaced knee and 39.9% had no particular preference. The overall prevalence of anterior knee pain was 8.3% in the resurfaced cases (3 mild, 1 moderate) and 27.1% in the unresurfaced knees (8 mild, 3 moderate, 2 severe). No significant difference was found between knee scores.

This study shows a significantly higher rate of anterior knee pain in unresurfaced patellae and preference for the resurfaced side.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 26 - 26
1 Jun 2012
Su E Chotai P
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Introduction

Alumina Ceramic liners are increasingly used in patients undergoing Total Hip Replacement (THR). The rate of fracture of ceramic liner is decreasing with improved manufacturing techniques from 1st to 3rd generation alumina-ceramic liners. We report the first case of a fracture of a modern, 4th generation alumina bearing ceramic liner, which incorporates a metal sheath to help avoid fracture. Our case is a 60 years old female presenting two years and three months after a bilateral total hip replacement using Stryker Trident cup, securfit stem and alumina on alumina bearing ceramic liner. Ceramic liners are commonly used, especially in young patients because of their excellent biocompatibility, low wear rate and superior tribology. Although fracture of ceramic liner is a less common complication of modern total hip arthroplasty, it is a major concern with the use of ceramic on ceramic THR, the reason being brittleness of ceramic. Cases of 3rd generation ceramic liner fracture have been reported which might be associated with impingement due to excessive anteversion of the socket in Asian patients who habitually squat. Habitual squatting, sitting cross legged and kneeling were not characteristic of this case.

Methods

The patient presented with complains of mechanical grinding in left hip. She also reported a past history of clicking sound from left hip on extension of left hip and long stride gait. There was no history of trauma or fall. On examination she had a nonantalgic gait and left hip had audible and palpable crepitations. The range of motion on left hip was intact with no subluxation. Right hip was symptom free and examination did not detect any abnormalities.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 309 - 309
1 Jul 2008
Daniel J Pradhan C Ziaee H McMinn D
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Introduction: Hip resurfacing is a good conservative option for young patients with arthritis. Resurfacings risk two unique failure mechanisms that do not occur in THA, i.e. femoral neck fracture and femoral head collapse.

Old age, osteopaenia, alcohol abuse, and large cysts are risk factors for fractures. It has been suggested that performing a bilateral resurfacing puts the first side at risk of fracture from the force used in implanting the second resurfacing. Is this a true risk or a sampling error?

Methods: Out of 2576 consecutive resurfacings performed by the senior author (July 1997 – May 2005), 191 patients (382 hips, 14.8% of all resurfacings) presented with bilateral arthritis and had both hips operated in the same hospital admission. 133 patients had the two operations a week apart and 58 had both the same day. A posterior approach was used in all cases with the patient in the lateral position on the contralateral side.

Results: Of the 382 resurfacings, only two failed from a femoral neck fracture. Both had the second operation a week after the first. A 35-year lady (rheumatoid arthritis) sustained a femoral neck fracture of the first hip following a fall nine weeks after the operation. A 57-year man (osteoarthritis) fractured his femoral neck at 3.5 months. He fractured the side operated second.

Discussion: The incidence of femoral neck fracture in the author’s series of 2576 resurfacings is 0.4%. Patients who present with bilateral severe arthritis are more likely to have non-primary OA such as inflammatory arthritis. It is difficult to conclude if such bilateral cases are more predisposed to a fracture by virtue of the pathology itself.

The low incidence of fractures (2/382, 0.5%) in this bilateral resurfacing series does not support the view that there is an increased risk of fracture from a bilateral procedure.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 244 - 245
1 May 2009
Davidson D Anis A Brauer C Mulpuri K
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Slipped capital femoral epiphysis (SCFE) is the most common pediatric hip disorder. The most devastating complication is development of avascular necrosis of the femoral head. In order to reduce the potential for this complication occurring following delayed contralateral SCFE, there has been consideration in the literature of prophylactic pinning of the contralateral hip. The objective of this study was to determine the cost-effectiveness of this treatment strategy.

The outcome probabilities and utilities utilised in a decision analysis of prophylactic pinning of the contralateral hip in SCFE, reported by Kocher et al, were used in this study. Costing data, reported in 2005 Canadian dollars, was obtained from our institution. Using this data, an economic evaluation was performed. The time horizon was four years, so as to follow the adolescents to skeletal maturity. Discounting was performed at 3% per year. Sensitivity analyses were conducted to determine the effect of variation of the outcome probabilities and utilities.

In all analyses, prophylactic pinning resulted in cost savings but lower utility, compared to the currently accepted strategy of observation of the contralateral hip. The results were most sensitive to an increase in the probability of a delayed contralateral SCFE to 27%. Using the base case analysis, the incremental cost-effectiveness ratio was $7856.12 per utility gained. Using the most sensitive probability of a delayed contralateral SCFE of 27%, the incremental cost-effectiveness ratio was $27,252.92 per utility gained.

The results of this study demonstrated overall cost savings with prophylactic treatment, however the utility was lower than the standard treatment of observation. For both the base case and sensitivity analysis, the incremental cost-effectiveness ratio was less than the accepted threshold of $50,000 per quality adjusted life year gained. It should be noted that the use of a four year time horizon excluded consideration of the costs related to total hip arthroplasty for the sequelae of AVN. A prospective, randomised controlled trial, with an accompanying economic evaluation, is required to definitively answer the question of the cost-effectiveness of this treatment. On the basis of this cost-effectiveness analysis, prophylactic pinning of the contralateral hip in SCFE cannot be recommended. A prospective, randomised controlled trial, with an accompanying economic evaluation, is required to definitively answer the question of the cost-effectiveness of this treatment.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 250 - 250
1 Jul 2008
NEHME A TROUSDALE R OAKES D MAALOUF G WEHBE J PUGET J
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Purpose of the study: Acetabular version is a most important parameter for repositioning the acetabular fragment during periacetabular osteotomy. Recently, a few studies have presented a significant number of dysplastic hips with acetabular retroversion. There have not however been any studies devoted specifically to the severity of bilateral acetabular retroversion. The purpose of this work was to determine the incidence of bilateral retroversion in patients undergoing periacetabular osteotomy for dysplasia in order to identify and validate a retroversion index which would be predictive of the degree of retroversion. This index could be added to congenital hip dysplasia classifications to include acetabular version.

Material and methods: The Lequesne lateral view of the hip was obtained in 174 patients (348 hips, 137 women and 37 men, mean age 30 years) undergoing periacetabular osteotomy for symptomatic dysplasia. One hundred ninety-five hips (56%) were operated on and 153 (44%) were considered normal or non-symptomatic and were not operated. The following parameters were noted for each hip: VCE, VCA, HTE, femoral head extrusion, index of acetabular depth, crossing-over, retroversion index. The retroversion index was checked on a bone model of the pelvis which was x-rayed in the neutral position then turned progressively. Statistical data were analyzed with SAS.

Results: Five percent of the operated hips presented neutral version, 53% anteversion and 42% retroversion. Twenty-four percent of the non-operated hips were normal, 22% presented pure retroversion and 54% were dysplastic. All of the measurements were significantly deviated towards dysplasia for operated hips, with the exception of the retroversion index and the VCA.

Discussion: These data validated the retroversion index and confirmed that one out of three dysplastic hips displays retroversion. In addition, it would appear that for dysplastic hips with retroversion, the degree of lateral coverage or the HTE angle determines whether surgery is needed or not and not the degree of retroversion. But as pure retroversion can be symptomatic in itself, and since the majority of these version or cover anomalies can be treated by periacetabular osteotomy, we propose a classification of hip dysplasia included acetabular version.

Conclusion: This classification is designed as an aid for the orthopedic surgeon for reorienting the acetabular fragment to obtain the optimal position.


Bone & Joint Open
Vol. 5, Issue 2 | Pages 79 - 86
1 Feb 2024
Sato R Hamada H Uemura K Takashima K Ando W Takao M Saito M Sugano N

Aims. This study aimed to investigate the incidence of ≥ 5 mm asymmetry in lower and whole leg lengths (LLs) in patients with unilateral osteoarthritis (OA) secondary to developmental dysplasia of the hip (DDH-OA) and primary hip osteoarthritis (PHOA), and the relationship between lower and whole LL asymmetries and femoral length asymmetry. Methods. In total, 116 patients who underwent unilateral total hip arthroplasty were included in this study. Of these, 93 had DDH-OA and 23 had PHOA. Patients with DDH-OA were categorized into three groups: Crowe grade I, II/III, and IV. Anatomical femoral length, femoral length greater trochanter (GT), femoral length lesser trochanter (LT), tibial length, foot height, lower LL, and whole LL were evaluated using preoperative CT data of the whole leg in the supine position. Asymmetry was evaluated in the Crowe I, II/III, IV, and PHOA groups. Results. The incidences of whole and lower LL asymmetries were 40%, 62.5%, 66.7%, and 26.1%, and 21.7%, 20.8%, 55.6%, and 8.7% in the Crowe I, II/III, and IV, and PHOA groups, respectively. The incidence of tibial length asymmetry was significantly higher in the Crowe IV group (44.4%) than that in the PHOA group (4.4%). In all, 50% of patients with DDH-OA with femoral length GT and LT asymmetries had lower LL asymmetry, and 75% had whole LL asymmetry. The incidences of lower and whole LL asymmetries were 20% and 42.9%, respectively, even in the absence of femoral length GT and LT asymmetries. Conclusion. Overall, 43% of patients with unilateral DDH-OA without femoral length asymmetry had whole LL asymmetry of ≥ 5 mm. Thus, both the femur length and whole LL should be measured to accurately assess LL discrepancy in patients with unilateral DDH-OA. Cite this article: Bone Jt Open 2024;5(2):79–86


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_13 | Pages 70 - 70
1 Dec 2022
Falsetto A Grant H Wood G
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Arthroscopic hip procedures have increased dramatically over the last decade as equipment and techniques have improved. Patients who require hip arthroscopy for femoroacetabular impingement on occasion require surgery on the contralateral hip. Previous studies have found that younger age of presentation and lower Charlson comorbidity index have higher risk for requiring surgery on the contralateral hip but have not found correlation to anatomic variables. The purpose of this study is to evaluate the factors that predispose a patient to requiring subsequent hip arthroscopy on the contralateral hip. This is an IRB-approved, single surgeon retrospective cohort study from an academic, tertiary referral centre. A chart review was conducted on 310 primary hip arthroscopy procedures from 2009-2020. We identified 62 cases that went on to have a hip arthroscopy on the contralateral side. The bilateral hip arthroscopy cohort was compared to unilateral cohort for sex, age, BMI, pre-op alpha angle and centre edge angle measured on AP pelvis XRay, femoral torsion, traction time, skin to skin time, Tonnis grade, intra-op labral or chondral defect. A p-value <0.05 was deemed significant. Of the 62 patients that required contralateral hip arthroscopy, the average age was 32.7 compared with 37.8 in the unilateral cohort (p = 0.01) and BMI was lower in the bilateral cohort (26.2) compared to the unilateral cohort (27.6) (p=0.04). The average alpha angle was 76.3. 0. in the bilateral compared to 66. 0. in the unilateral cohort (p = 0.01). Skin to skin time was longer in cases in which a contralateral surgery was performed (106.3 mins vs 86.4 mins) (p=0.01). Interestingly, 50 male patients required contralateral hip arthroscopy compared to 12 female patients (p=0.01). No other variables were statistically significant. In conclusion, this study does re-enforce existing literature by stating that younger patients are more likely to require contralateral hip arthroscopy. This may be due to the fact that these patients require increased range of motion from the hip joint to perform activities such as sports where as older patients may not need the same amount of range of motion to perform their activities. Significantly higher alpha angles were noted in patients requiring contralateral hip arthroscopy, which has not been shown in previous literature. This helps to explain that larger CAM deformities will likely require contralateral hip arthroscopy because these patients likely impinge more during simple activities of daily living. Contralateral hip arthroscopy is also more common in male patients who typically have a larger CAM deformity. In summary, this study will help to risk stratify patients who will likely require contralateral hip arthroscopy and should be a discussion point during pre-operative counseling. That offering early subsequent or simultaneous hip arthroscopy in young male patients with large CAMs should be offered when symptoms are mild


The Bone & Joint Journal
Vol. 103-B, Issue 8 | Pages 1345 - 1350
1 Aug 2021
Czubak-Wrzosek M Nitek Z Sztwiertnia P Czubak J Grzelecki D Kowalczewski J Tyrakowski M

Aims. The aim of the study was to compare two methods of calculating pelvic incidence (PI) and pelvic tilt (PT), either by using the femoral heads or acetabular domes to determine the bicoxofemoral axis, in patients with unilateral or bilateral primary hip osteoarthritis (OA). Methods. PI and PT were measured on standing lateral radiographs of the spine in two groups: 50 patients with unilateral (Group I) and 50 patients with bilateral hip OA (Group II), using the femoral heads or acetabular domes to define the bicoxofemoral axis. Agreement between the methods was determined by intraclass correlation coefficient (ICC) and the standard error of measurement (SEm). The intraobserver reproducibility and interobserver reliability of the two methods were analyzed on 31 radiographs in both groups to calculate ICC and SEm. Results. In both groups, excellent agreement between the two methods was obtained, with ICC of 0.99 and SEm 0.3° for Group I, and ICC 0.99 and SEm 0.4° for Group II. The intraobserver reproducibility was excellent for both methods in both groups, with an ICC of at least 0.97 and SEm not exceeding 0.8°. The study also revealed excellent interobserver reliability for both methods in both groups, with ICC 0.99 and SEm 0.5° or less. Conclusion. Either the femoral heads or acetabular domes can be used to define the bicoxofemoral axis on the lateral standing radiographs of the spine for measuring PI and PT in patients with idiopathic unilateral or bilateral hip OA. Cite this article: Bone Joint J 2021;103-B(8):1345–1350


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_2 | Pages 113 - 113
2 Jan 2024
García-Rey E Gómez-Barrena E
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Pelvic bone defect in patients with severe congenital dysplasia of the hip (CDH) lead to abnormalities in lumbar spine and lower limb alignment that can determine total hip arthroplasty (THA) patients' outcome. These variables may be different in uni- or bilateral CDH. We compared the clinical outcome and the spinopelvic and lower limb radiological changes over time in patients undergoing THA due to uni- or bilateral CHD at a minimum follow-up of five years. Sixty-four patients (77 hips) undergoing THA due to severe CDH between 2006 and 2015 were analyzed: Group 1 consisted of 51 patients with unilateral CDH, and group 2, 113 patients (26 hips) with bilateral CDH. There were 32 females in group 1 and 18 in group 2 (p=0.6). The mean age was 41.6 years in group 1 and 53.6 in group 2 (p<0.001). We compared the hip, spine and knee clinical outcomes. The radiological analysis included the postoperative hip reconstruction, and the evolution of the coronal and sagittal spinopelvic parameters assessing the pelvic obliquity (PO) and the sacro-femoro-pubic (SFP) angles, and the knee mechanical axis evaluating the tibio-femoral angle (TFA). At latest follow-up, the mean Harris Hip Score was 88.6 in group 1 and 90.7 in group 2 (p=0.025). Postoperative leg length discrepancy of more than 5 mm was more frequent in group 1 (p=0.028). Postoperative lumbar back pain was reported in 23.4% of the cases and knee pain in 20.8%, however, there were no differences between groups. One supracondylar femoral osteotomy and one total knee arthroplasty were required. The radiological reconstruction of the hip was similar in both groups. The PO angle improved more in group 1 (p=0.01) from the preoperative to 6-weeks postoperative and was constant at 5 years. The SFP angle improved in both groups but there were no differences between groups (p=0.5). 30 patients in group 1 showed a TFA less than 10º and 17 in group 2 (p=0.7). Although the clinical outcome was better in terms of hip function in patients with bilateral CDH than those with unilateral CDH, the improvement in low back and knee pain was similar. Patients with unilateral dysplasia showed a better correction of the PO after THA. All spinopelvic and knee alignment parameters were corrected and maintained over time in most cases five years after THA