Objectives.
Aims.
Objectives.
Aims. To assess the safety of
Objectives. We have increased the dose of
Aims. The intra-articular administration of
Aims.
Aims.
Aims.
Aims. The purpose of this study was to examine the efficacy and safety of carbazochrome sodium sulfonate (CSS) combined with
Aims. The aims of this study were to compare the efficacy and safety
of intra-articular and intravenous (IV)
Aims. We chose unstable extra-capsular hip fractures as our study group
because these types of fractures suffer the largest blood loss.
We hypothesised that
Intravenous
Aims. The aim of this study was to investigate the hypothesis that a single dose of
Aims. Cementless primary total hip arthroplasty (THA) is associated with risks of bleeding and thromboembolism. Anticoagulants are effective as venous thromboprophylaxis, but with an increased risk of bleeding.
The use of antifibrinolytic drugs and many other agents have a critical importance in bleeding control.
Background. Total joint replacement surgery is associated with large amounts of blood loss and significant rates of transfusions. Postoperative bleeding is one of the most important problems after major orthopedic surgeries including revision Total Hip Arthroplasty (THA). It has been demonstrate that
Aims. This study investigated whether the use of
Background:
We performed a randomised, controlled trial involving 150 patients with a pre-operative level of haemoglobin of 13.0 g/dl or less, to compare the effect of either topical fibrin spray or intravenous
Abstract. By next summer the number of patients in the
Aim We have prospectively investigated the effect of
Introduction: Numerous studies have been carried out to assess the efficacy of
Purpose. Topical application of
Background:. Role of intra-articular
Background: Total hip replacement (THR) is one of the commonest operations in orthopaedic practice. Literature review showed that 20–70% of patients who underwent THR needed 1–3 units of blood. Although safer than ever, allogeneic transfusion is still associated with risks for the recipient. There has been unsettled search for ways to reduce such blood loss and transfusion.
Background. Tourniquets and
Background. The reductions of perioperative blood loss and inflammatory response are important in total knee arthroplasty.
Introduction: Knee replacement surgery is associated with minimal intraoperative blood loss, but marked postoperativelloss. Allogenic blood transfusions are associated with known risks. The need to establish programmes of blood conservation in knee replacement surgery becomes evident. We present a retrospective comparative study of 3 blood salvage methods used in TKR: autologous blood donation, cell saver and tranexamico acid. The purpose of this study is to asses the results of
A prospective, randomized, double-blind study was done on 50 patients undergoing primary cementless total hip arthroplasty to determine the effect of
A prospective, randomized, double-blind study was done on 50 patients undergoing primary cementless total hip arthroplasty to determine the effect of
The effectiveness of intravenous
To compare the efficacy of intra-articular and intravenous modes of administration of
Total joint arthroplasty is one of the most common procedures performed in orthopaedic surgery. Over 600,000 total hip and total knee replacements are performed in the United States each year. At our 550 bed tertiary care facility, 437 total knee arthroplasties were performed in 2010 and 426 in 2011.
The effect of intra-articular
Introduction.
Introduction: Today’s aging population has resulted in an increase in the number of major orthopaedic surgical interventions in the elderly. Total knee replacement (TKR) is one of the commonest operations in orthopaedic practice. The fourth annual report of the National Joint Registry showed that there were 60 986 TKR performed in England and Wales in 2006. The true figure is probably much higher. Literature showed that 20–70% of patients who had TKR needed 1–3 units of blood. Although safer than ever, allogeneic transfusion is still associated with risks for the recipient (haemolysis, infection, immunosuppression, transfusion-related acute lung injury and even death).
Total hip arthroplasty (THA) is associated with high intraoperative and postoperative blood loss. Antifibrinolytic drugs have been used to minimize the potential risks of bleeding and blood transfusion. Studies on the effect of
Background.
Purpose. The hip fracture has been increasing as the aging population continues to grow. Hip fracture patients are more susceptible to blood loss and venous thromboembolism (VTE). The objective of this study was to assess the efficacy and safety of
Aims: To demonstrate that
Introduction & Aims. Intravenous administration of
Background.
The aim of this study was to determine the effectiveness of intra-operative
PURPOSE OF STUDY. 20-70% of patients need blood transfusion postoperatively. There remain safety concerns regarding allogenic blood transfusion.
We carried out a retrospective case-control study in 80 patients who underwent a revision total hip replacement. Group A (40 patients) received
Aims. Antifibrinolytic agents, including
To compare the efficacy of intra-articular and intravenous modes of administration of
Introduction. We examined the effect on blood loss of two standardised intravenous bolus doses of 500 mg of
Abstract. Introduction. Multiple strategies, used either in isolation or combination, are available to reduce the need for post-operative blood transfusion in joint replacements. Amongst them, the use of
We investigated the effect of a fibrinolytic inhibitor,
In this study we evaluate whether a single dose of intravenous
Aims. A typical pattern of blood loss associated with total hip arthroplasty (THA) is 200 ml intraoperatively and 1.3 l in the first 48 postoperative hours.
Aim. To investigate the effect of
Introduction.
Background. Intravenous and topical
Primary hip and knee replacements can be associated with significant blood loss.
We report a systematic review and meta-analysis of published randomised controlled trials evaluating the efficacy of
Background. 91% of blood loss in Total Hip Replacement (THR) occurs in the period after skin closure and the first 24 post-operative hours. TRAC-24 was established to identify if an additional 24-hour post-operative oral regime of
INTRODUCTION.
INTRODUCTION.
Introduction: Reinfusion drains are used to minimise the need for allogenic blood transfusion, and its potential complications.
Patients and Methods: One hundred and fifty patients with pre-operative haemoglobin levels of 13.0g/dl or less were enrolled into a randomised controlled trial comparing the blood saving effect of intravenous
Introduction.
Introduction and Objective.
Abstract. Objectives. to evaluate the efficacy and safety of topically applied
Adequate visual clarity is paramount to performing arthroscopic shoulder surgery safely, efficiently, and effectively. The addition of epinephrine in irrigation fluid, and the intravenous or local administration of
Adequate visual clarity is paramount to performing arthroscopic shoulder surgery safely, efficiently, and effectively. The addition of epinephrine in irrigation fluid, and the intravenous or local administration of
Purpose. The purpose of this study was to assess the efficacy of newly designed topical administration of
The risk of venous thrombo-embolism (VTE) is high in orthopedics. Oral direct factor Xa inhibitors have been introduced to help reduce the incidence of VTE. To reduce post-operative bleeding antifibrinolytics are used. We aimed to ascertain the effect of two drugs on post operative bleeding and transfusion requirements. We prospectively recorded patient demographics, operative details, complications, transfusion incidence and VTE incidence in TKR patients. We also sent out questionnaires to patients asking about wound bleeding and VTE. All patients were given 10mg Rivaroxaban 8 hours post operatively and then OD for 14 or 35 days. Patients given
The risk of venous thrombo-embolism (VTE) is high in orthopaedics. Oral direct factor Xa inhibitors have been introduced to help reduce the incidence of VTE. To reduce post-operative bleeding antifibrinolytics are used. We aimed to ascertain the effect of two drugs on post-operative bleeding and transfusion requirements. We prospectively recorded patient demographics, operative details, complications, transfusion incidence and VTE incidence in TKR patients. We also sent out a questionnaire to patients asking about wound bleeding and VTE. All patients were given 10mg Rivaroxaban 8 hours post operatively and then once a day for 14 days. Patients given
Introduction. Bilateral total knee arthroplasty (TKA) results in substantial perioperative blood loss with increased morbidity.
Background.
Background.
Blood loss following total hip replacement is a major contributor to increase morbidity and length of stay. Various techniques have been described to reduce its occurrence. We now follow a set protocol, combining rivaroxaban for thrombo-prophylaxis and
Aims. The aim of this study was to identify the most effective regimen
of multiple doses of oral
Objectives. To investigate the value of
Background. The use of
Introduction. Allogeneic blood transfusion (ABT) remains a widely used therapeutic intervention in patients undergoing total knee arthroplasty (TKA). There is mounting evidence that
Background. The purpose of this multicenter, randomized clinical trial was to determine the optimal dosing regimen of
Introduction: Surgery and the use of pneumatic tourniquets lead to an increase in the activity of the fibrinolytic system, which in turn may accentuate the blood loss during knee arthroplasty. Drugs that inhibit the fibrinolytic system may thus be used to reduce blood loss.
Introduction. Total knee replacements (TKR) are among the commonest operations performed in orthopaedic practice. Literature review showed that 10-30% of patients who underwent TKR needed 1-3 units of blood.
Purpose. This meta-analysis was designed to compare the effectiveness and safety of intravenous (IV) versus topical administration of
Aims. In total knee arthroplasty (TKA), blood loss continues internally after surgery is complete. Typically, the total loss over 48 postoperative hours can be around 1,300 ml, with most occurring within the first 24 hours. We hypothesize that the full potential of
Introduction.
We conducted a retrospective study to compare the blood loss following Primary Total Knee Replacement (TKR) to see effectiveness of
Introduction: We performed a retrospective case control study in 80 patients who under went revision hip surgery at our unit. Methodology: Group A (40 patients), received
Background. While
Background. Intraoperative blood loss is a known potential complication of total knee arthroplasty (TKA).