Aims. This work aimed at answering the following research questions: 1) What is the rate of mechanical complications, nonunion and infection for head/neck
Aims. The impact of concomitant injuries in patients with proximal
Aims. Proximal
Aims. The prevalence of ipsilateral total hip arthroplasty (THA) and total knee arthroplasty (TKA) is rising in concert with life expectancy, putting more patients at risk for interprosthetic
Aims. Current American Academy of Orthopaedic Surgeons (AAOS) guidelines for treating
Aims. Periprosthetic proximal
Aims. Impaired fracture repair in patients with type 2 diabetes mellitus (T2DM) is not fully understood. In this study, we aimed to characterize the local changes in gene expression (GE) associated with diabetic fracture. We used an unbiased approach to compare GE in the fracture callus of Zucker diabetic fatty (ZDF) rats relative to wild-type (WT) littermates at three weeks following femoral osteotomy. Methods. Zucker rats, WT and homozygous for leptin receptor mutation (ZDF), were fed a moderately high-fat diet to induce T2DM only in the ZDF animals. At ten weeks of age, open
Introduction. Pediatric
Aims. The incidence of atypical
Aims. Treatment guidelines for atypical
Aims. Patients with proximal
Aims. Currently, periprosthetic fractures are excluded from the American Society for Bone and Mineral Research (ASBMR) definition of atypical
Introduction. This study aimed to compare MIPO and IMNr in the treatment of supracondylar
Abstract. Background. Atypical
An atypical
Objectives. One commonly used rat fracture model for bone and mineral research
is a closed mid-shaft
Peri-prosthetic
Aims. A proximal
The results of the treatment of 31 open
Objectives. MicroRNAs (miRNAs) have been reported as key regulators of bone formation, signalling, and repair. Fracture healing is a proliferative physiological process where the body facilitates the repair of a bone fracture. The aim of our study was to explore the effects of microRNA-186 (miR-186) on fracture healing through the bone morphogenetic protein (BMP) signalling pathway by binding to Smad family member 6 (SMAD6) in a mouse model of