Failure of metal on metal (MOM) total hip arthroplasty (THA) and resurfacing arthroplasty (HRA) due to development of adverse local tissue reaction (ALTRs) is a significant problem. The prevalence of ALTRs in asymptomatic MOM arthroplasty patients is highly variable. The purpose of this prospective, longitudinal study was to: 1) determine MRI ALTR prevalence in patients with HRA; 2) determine if patients with HRA have a greater rate of MRI ALTRs compared to control patients with ceramic on poly (COP) THA; and 3) evaluate changes in patient reported outcomes between these implant designs. Following IRB approval with informed consent, self-reported asymptomatic primary COP and HRA patients greater than one year post arthroplasty were evaluated with 4 annual (TP1–4) MRIs using a standardized protocol and serum ion level testing. Morphologic and susceptibility reduced images were acquired for each hip and evaluated for synovial thickness, volume, capsule dehiscence and the presence of ALTR. Patient reported outcomes were evaluated by Hip Disability and Osteoarthritis Outcome Scores (HOOS). Analyses were performed to detect differences of synovial thickness and volume, and HOOS subgroups between and within bearing surfaces at each time point and over time, and to compare the time to and the risk of developing MRI ALTR. Analyses were adjusted for age, gender, and length of implantation.Introduction
Methods
The Birmingham Hip Resurfacing (Smith & Nephew London, UK) is the most popular hip resurfacing (HR) in the UK. However, it is now subject to two Medical Device Alerts (MDA) from the Medicines and Healthcare products Regulatory Agency (MHRA). A cross-sectional survey of primary metal-on-metal hip procedures recorded on the National Joint Registry for England, Wales and Northern Ireland (NJR) until 5th November 2013 was performed. Cost-analysis was based on an algorithm for surveillance of HR at a tertiary referral centre and followed previous MHRA guidance. NIHR NHS Treatment costs were used. The local protocol encompassed: patient outcome scoring (Oxford hip score), blood metal ion measurement (cobalt, chromium), cross-sectional imaging (MRI) and discussion at an internet-enabled multidisciplinary team meeting (iMDT) in addition to routine hip surveillance.Introduction
Patients/Materials & Methods
Patients from a randomised trial on resurfacing
hip arthroplasty (RHA) (n = 36, 19 males; median age 57 years, 24
to 65) comparing a conventional 28 mm metal-on-metal total hip arthroplasty
(MoM THA) (n = 28, 17 males; median age 59 years, 37 to 65) and
a matched control group of asymptomatic patients with a 32 mm ceramic-on-polyethylene
(CoP) THA (n = 33, 18 males; median age 63 years, 38 to 71) were
cross-sectionally screened with metal artefact reducing sequence-MRI
(MARS-MRI) for pseudotumour formation at a median of 55 months (23
to 72) post-operatively. MRIs were scored by consensus according
to three different classification systems for pseudotumour formation. Clinical scores were available for all patients and metal ion
levels for MoM bearing patients. Periprosthetic lesions with a median volume of 16 mL (1.5 to
35.9) were diagnosed in six patients in the RHA group (17%), one
in the MoM THA group (4%) and six in the CoP group (18%). The classification
systems revealed no clear differences between the groups. Solid
lesions (n = 3) were exclusively encountered in the RHA group. Two patients
in the RHA group and one in the MoM THA group underwent a revision
for pseudotumour formation. There was no statistically significant
relationship between clinical scoring, metal ion levels and periprosthetic
lesions in any of the groups. Periprosthetic fluid collections are seen on MARS-MRI after conventional
CoP THA and RHA and may reflect a soft-tissue collection or effusion. Currently available MRI classification systems seem to score
these collections as pseudotumours, causing an-overestimatation
of the incidence of pseudotumours. Cite this article:
Metal on metal articulations produce chromium (Cr) and cobalt (Co) debris, particularly when the articulations are worn in. High levels in the peripheral blood are indicative of excess wear and may cause adverse effects. The present RCT investigates metal ion levels and the relationship of Co, Cr ions and lymphocyte counts during the running-in period. Following randomization to RHA (ASRTM, DePuy) or THA we obtained whole blood (wb), and serum (s) samples at baseline, 8 w, 6 m and 1 y. We measured the Co and Cr concentrations, the total lymphocyte count as well as the CD3+, CD4+, CD8+, CD19+ and CD16+/CD56+ sub populations. Cup inclination and anteversion angles came from conventional radiographs. Activity was measured as steps by pedometer and UCLA activity. Data are presented as median (range).Introduction
Materials and Methods
This study examined whether TiNbN surface characteristics can reduce corrosion and wear of Chrome Cobalt Molybdenum Metal-on Metal bearings. Two series of patients had plasma concentrations of chromium and cobalt at intervals following surgery. The First Series comprised a retrospective analysis of 52 consecutive cases (49 patients, 73–96 months following operation; age at surgery: 33–78) who had undergone an ACCIS (Implantcast, Germany) Modular Large Head hip replacement. The Second Series comprised a prospective, consecutive series of 125 cases (109 patients, 1–61 months following operation; age at surgery: 24–75) who had undergone an ACCIS
It is accepted that resurfacing hip replacement
preserves the bone mineral density (BMD) of the femur better than total
hip replacement (THR). However, no studies have investigated any
possible difference on the acetabular side. Between April 2007 and March 2009, 39 patients were randomised
into two groups to receive either a resurfacing or a THR and were
followed for two years. One patient’s resurfacing subsequently failed,
leaving 19 patients in each group. Resurfaced replacements maintained proximal femoral BMD and,
compared with THR, had an increased bone mineral density in Gruen
zones 2, 3, 6, and particularly zone 7, with a gain of 7.5% (95%
confidence interval (CI) 2.6 to 12.5) compared with a loss of 14.6%
(95% CI 7.6 to 21.6). Resurfacing replacements maintained the BMD
of the medial femoral neck and increased that in the lateral zones
between 12.8% (95% CI 4.3 to 21.4) and 25.9% (95% CI 7.1 to 44.6). On the acetabular side, BMD was similar in every zone at each
point in time. The mean BMD of all acetabular regions in the resurfaced
group was reduced to 96.2% (95% CI 93.7 to 98.6) and for the total
hip replacement group to 97.6% (95% CI 93.7 to 101.5) (p = 0.4863).
A mean total loss of 3.7% (95% CI 1.0 to 6.5) and 4.9% (95% CI 0.8
to 9.0) of BMD was found above the acetabular component in W1 and
10.2% (95% CI 0.9 to 19.4) and 9.1% (95% CI 3.8 to 14.4) medial
to the implant in W2 for resurfaced replacements and THRs respectively.
Resurfacing resulted in a mean loss of BMD of 6.7% (95% CI 0.7 to
12.7) in W3 but the BMD inferior to the acetabular component was
maintained in both groups. These results suggest that the ability of a resurfacing hip replacement
to preserve BMD only applies to the femoral side.
Current standard cups of metal on metal resurfacing hip arthroplasty (RHA) have no dome holes and it is very difficult for surgeons to confirm full seating of these cups. This sometimes results in gap formation between the cup and acetabular floor. Although the incidence of initial gaps using modular press-fit cups with dome screw holes has been reported to range from 20 to 35%, few studies have reported the incidence of gap formation with monoblock metal cups and its clinical consequences in RHA. The purpose of this study was to investigate retrospectively the incidence of initial gap formation and whether the initial gap influences the clinical results in RHA. RHA was performed on 166 hips of 146 patients using the Birmingham Hip Resurfacing (BHR) (MMT, UK) between 1998 and 2007. Mean age at operation was 48.7 years (range, 19-85 years). Mean duration of follow-up was 6.9 years (2.0-10.6). Acetabular reaming was performed with the use of hemispherical reamers and the reamer size was increased up to an odd number diameter which provided tight rim fit in the antero-posterior direction. The same size hemispherical provisional cup with dome holes and slits was used to check the cavity for complete seating. If the provisional cup could not be seated on the floor, reaming was repeated with the same reamer to remove the rim bump until full seating was achieved. Acetabular cups of 1mm larger diameter were impacted into the acetabulum by a press-fit technique. After press-fit fixation, the stability of the cups was confirmed with a synchronized movement of the pelvis and the cup inserter by applying a gentle torque. Clinical evaluation was performed using WOMAC at the latest follow-up. Radiographic assessments were performed using radiographs immediately after the surgery, at 3 weeks, 3 months, 1 year, and then annually thereafter. We evaluated the height of the gap between the cup and acetabular surface, cup inclination angle, cup migration and the time to gap filling. To investigate the relationship between the magnitude of the gap and the radiographic results, the patients were divided into two groups according to the height of the initial gap; the cases with a gap of less than 3 mm on the initial radiograph were grouped into a small gap group, the cases with a gap of 3mm or more were grouped into a large gap group. We compared the changes in the height of the gap, in the cup inclination angle and the cup migration between the groups.Introduction
Material and Method
Correct positioning of the femoral component in resurfacing hip arthroplasty (RHA) is an important factor in successful long-term outcomes. The purpose of computer-assisted navigation (CAS) in resurfacing is to insert the femoral neck guide wire with greater accuracy and to help size the femoral component, thus reducing the risk of notching at the head and neck junction. Several recent studies reported satisfactory precision and accuracy of CAS. However, there is little evidence that CAS is useful in the presence of anatomical deformities of the proximal femur, which is frequently observed in young patients with secondary degenerative joint disease. The purpose of this in vitro study was to determine the accuracy of an image-free RHA navigation system in the presence of angular deformity of the neck, pistol grip deformity of the head and neck junction and slipped upper femoral epiphysis deformity.Background
Aim
Background:
Aim: We studied the payments received by our hospital for 109 elective lower limb arthroplasty cases to see if this was fair and consistent under Payment by Results. Methods: A cohort of patients who had Total Hip Replacement (THR), Total Knee Replacement (TKR),
Introduction:
Implant malposition is one of the most common causes of failure in resurfacing arthroplasty of the hip (RAH). Recent advances in computer technology have made available navigation systems for RAH and other orthopaedic procedures. The purpose of our study was:
to develop a method to assess the accuracy of an image-free RAH navigation system; to assess its accuracy in a leg with normal anatomy and with deformity of the proximal femur. We used the Ci-CAS RAH navigation system (DePuy - BrainLab). To facilitate measurements, an artificial leg (phantom) was constructed from machined aluminium with simulated hip and knee joints. The hip and knee articulating surfaces were synthetic bone material (Sawbones – Pacific Laboratories). An additional joint located at the trochanteric region allowed deformation in varus/valgus and ante/retroversion of the head/neck segment. Using a highly accurate digital calliper unit (FaroARM Technologies, USA) to precisely measure co-ordinates with pre-machined points on the phantom, a software program was developed to convert these local co-ordinates into a determination of actual anatomy and leg alignment. This technique was verified using repeated measurement with variable co-ordinates, giving accuracy to within 0.05 of a degree. Simulated procedures were performed with both normal and abnormal anatomy of the proximal femur. At specific points in the procedure, information was compared between the FaroARM digital measurements and the Ci-CAS system. Repeated serial measurements were undertaken. In the setting of normal alignment, accuracy to within 0.5 degrees was demonstrated. In the setting of abnormal alignment (varus/valgus and ante/retroversion) of the proximal femur, accuracy to within 2 degrees was demonstrated. To our knowledge, this is the first study to assess accuracy of a RAH navigation system. The study demonstrates a satisfactory level of accuracy for the Ci-CAS in both normal and abnormal anatomical settings. Currently, no international standard or methodology exists against which these results can be compared. In the near future, introduction of new navigation technologies will make crucial the development of international standards for pre-clinical validation of computer-assisted navigation systems. The present study is a first attempt to address this issue.
Introduction: Prevalence of femoral neck fracture in resurfacing hip arthroplasty continues to question if failure is technique-related or due to the inherent bone quality. This study aimed to correlate cement penetration profile during resurfacing hip with inherent bone density. The hypothesis is that osteoporotic bone is unable to support the prosthesis leading to fatigue failure. Methods: Fifteen patients scheduled for total hip replacement (THR) were recruited to undergo resurfacing arthroplasty prior to THR. Each patient was implanted with a resurfacing femoral component (BHR, Smith &
Nephew, Memphis, TN). Antibiotic simplex cement was inserted one minute after mixing at 18°C to fill 10% of the femoral component volume. The femoral head-implant section was removed and kept in buffered formalin. The patients then proceeded with standard THR. The femoral head-cement-prosthesis section was separated using electrical discharge (ED) machining technique and CT-scanned. The depth and volume of cement penetration were measured from the CT scans and correlated with femoral neck bone densities. Results: Cement penetration was compared for three groups of bone density: normal, osteopenic, osteoporotic. Average cement thickness were found to be 0.36 ± 0.16mm (proximal), 0.28 ± 0.11 mm (centre) and 0.12 ± 0.05 mm. During hip resurfacing, cement is forced into the porous structure, e.g. the trabeculae and airspaces when the femoral component is fixed onto the head of the femur. In normal bone, the trabeculae is dense and air spaces occupy a small volume of the bone. Greater cement penetration was expected in osteopenic and osteoporotic bones. However, no significant difference was found between cement thickness and volume against inherent patient bone density (p>
0.05). High viscosity of the cement may have prevented more cement to penetrate the bone. While the exterior cortex of the femoral head is strengthened by a cement layer, the interior structure of the femoral neck is still susceptible to fracture at high loads. In addition, increased bone necrosis due to the exothermic reaction during cement fixation may predispose patients to fracture. Discussion:
Aim: To test the accuracy of implant positioning in using computer navigation in
Aim: To test the accuracy of implant positioning in using computer navigation in
The authors report their preliminary experience with a minimum of one year follow –up of hydroxyapatite coating as the means of fixation of the femoral head in hip resurfacing. Between Dec 2003 and Dec 2004, of the 23 cases performed by the senior author,22 were available for follow up,15 were women (68.2%) and 7 were men (31.8). The femoral and acetabular components of the uncemented version of the CORMET 2000(Corin,Cire ncester,UK) were used. The surgical approach was the Hardinge approach in all cases. Patients were assessed pre-operatively for pain and function,using the Harris Hip Score. Post operatively they were assessed in clinic with x rays at 6 weeks,6 months and annually thereafter. X rays were evaluated for pre and post op neck shaft angle,giving an indication of varus or valgus placement of the head prosthesis. The lateral view was assessed to reveal anterior or posterior tilting of the prosthesis. Neck thinning was evaluated by measuring the ratio of the metal cup and bony neck diameters at the cup neck junction, recorded post op and at one year. None of the femoral implants were placed in varus. Only one case had inferior notching, which had remodelled at one year. In the lateral view none of the cups showed a displacement of more than ten degrees in the AP direction. There were no stem lucencies or signs of femoral implant migration in any of the cases. None of our cases showed neck thinning (change in ratio greater than 10%). Uncemented femoral implant in a metal on metal resurfacing hip replacement appears to perform well and shows no catastrophic problems at the short term one year follow up. Longer follow up studies are necessary