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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_2 | Pages 60 - 60
10 Feb 2023
Daly D Maxwell R
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The purpose of this study is to assess the long term results of combined ACL reconstruction and unicompartmental knee replacements (UKR). These patients have been selected for this combined operation due to their combination of instability symptoms from an absent ACL and unicompartmental arthritis. Retrospective review of 44 combined UKR and ACL reconstruction by a single surgeon. Surgeries included both medial and lateral UKR combined with either revision ACL reconstruction or primary ACL reconstruction. Patient reported outcomes were obtained preoperatively, at one year, 5 years and 10 years. Revision rate was followed up over 13 years for a mean of 7.4 years post-surgery. The average Oxford score at one year was 43 with an average increase from pre-operation to 1 year post operation of 15. For the 7 patients with 10 year follow up average oxford score was 42 at 1 year, 43 at 5 years and 45 at 10 years. There were 5 reoperations. 2 for revision to total knee arthroplasty and 1 for an exchange of bearing due to wear. The other 2 were the addition of another UKR. For those requiring reoperation the average time was 8 years. Younger more active patients presenting with ACL deficiency causing instability and unicompartmental arthritis are a difficult group to manage. Combining UKR and ACL reconstruction has scant evidence in regard to long term follow up but is a viable option for this select group. This paper has one of the largest cohorts with a reasonable follow up averaging 7.4 years and a revision rate of 11 percent. Combined unilateral knee replacements and ACL reconstruction can be a successful operation for patients with ACL rupture causing instability and unicompartmental arthritis


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_9 | Pages 22 - 22
1 Oct 2020
Dodd CAF Kennedy J Murray DW
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Background. Lateral Unicompartmental Knee Arthroplasty (UKA) is a recognised treatment option in the management of lateral Osteoarthritis (OA) of the knee. Whilst there is extensive evidence on the indications and contraindcations in Medial UKA there is limited evidence on this topic in Lateral UKA. The aim of this study was to assess our experience of mobile lateral UKR and to look specifically at the effect of Contraindications on the outcome. Method. A total of 325 consecutive domed lateral UKAs undertaken for the recommended indications were included, and their functional and survival outcomes were assessed. The effects of age, weight, activity, and presence of full- thickness erosions of cartilage in the patellofemoral joint on outcome were evaluated. Results. Median follow- up was seven years (3 to 14), and mean age at surgery was 65 years (39 to 90). Median Oxford Knee Score (OKS) was 43 (interquartile range (IQR) 37 to 47), with 260 (80%) achieving a good or excellent score (OKS > 34). Revisions occurred in 34 (10%). In total, 14 (4%) were for dislocation, of which 12 had no recurrence following insertion of a new bearing. In all, 12 (4%) were revised for medial osteoarthritis (OA). Ten- year survival was 85% (95% confidence interval (CI) 79 to 90, at risk 72). Age, weight, activity, and patellofemoral erosions did not have a significant effect on the clinical outcome or survival. Conclusion. Mobile (domed) lateral UKA provides a good alternative to total knee arthroplasty (TKA) in the management of lateral compartment OA. Although dislocation is relatively easy to treat successfully, the dislocation rate of 4% is high. Younger age, heavier weight, high activity, and patellofemoral erosions did not detrimentally affect outcome, so should not be considered contraindications


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_8 | Pages 30 - 30
1 May 2016
Newman S Clarke S Harris S Cobb J
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Introduction. Patient Specific Instrumentation (PSI) has the potential to allow surgeons to perform procedures more accurately, at lower cost and faster than conventional instrumentation. However, studies using PSI have failed to convincingly demonstrate any of these benefits clinically. The influence of guide design on the accuracy of placement of PSI has received no attention within the literature. Our experience has suggested that surgeons gain greater benefit from PSI when undertaking procedures they are less familiar with. Lateral unicompartmental knee replacement (UKR) is relatively infrequently performed and may be an example of an operation for which PSI would be of benefit. We aimed to investigate the impact on accuracy of PSI with respect to the area of contact, the nature of the contact (smooth or studded guide surfaces) and the effect of increasing the number of contact points in different planes. Method. A standard anatomy tibial Sawbone was selected for use in the study and a computed tomography scan obtained to facilitate the production of PSI. Nylon PSI guides were printed on the basis of a lateral UKR plan devised by an orthopaedic surgeon. A control PSI guide with similar dimensions to the cutting block of the Oxford Phase 3 UKR tibial guide was produced, contoured to the anterior tibial surface with multiple studs on the tibial contact surface. Variants of this guide were designed to assess the impact of design features on accuracy. These were: a studded guide with a 40% reduction in tibial contact area, a non-studded version of the control guide, the control guide with a shim to provide articular contact, a guide with an extension to allow distal referencing at the ankle and a guide with a distal extension and an articular shim. All guides were designed with an appendage that facilitated direct attachment to a navigation machine (figure 1). 36 volunteers were asked to place each guide on the tibia with reference to a 3D model of the operative plan. The order of placement was varied using a counterbalanced latin square design to limit the impact of the learning effect. The navigation machine recorded deviations from the plan in respect of proximal-distal and medial-lateral translations as well as rotation around all three axes. Statistical analysis was performed on the compound translational and rotational errors for each guide using ANOVA with Bonferroni correction with statistical significance at p<0.05. Results. Contact points in greater than one plane led to a trend for increasing accuracy and precision of PSI guide placement with respect to rotational alignment, this achieved statistical significance relative to the control guide only with the guide that included articular and distal contact points (figure 2). No significant differences were found with respect to translation. Changes in contact area within the same plane and the use of smooth or studded contact points made no significant difference to accuracy. Conclusion. PSI guide design significantly impacts on accuracy of placement. PSI guides for UKR should endeavour to include widely separated reference points in different planes to maximise rotational accuracy


The Bone & Joint Journal
Vol. 97-B, Issue 11 | Pages 1493 - 1499
1 Nov 2015
Pandit H Hamilton TW Jenkins C Mellon SJ Dodd CAF Murray DW

This prospective study reports the 15-year survival and ten-year functional outcome of a consecutive series of 1000 minimally invasive Phase 3 Oxford medial UKAs (818 patients, 393 men, 48%, 425 women, 52%, mean age 66 years; 32 to 88). These were implanted by two surgeons involved with the design of the prosthesis to treat anteromedial osteoarthritis and spontaneous osteonecrosis of the knee, which are recommended indications. Patients were prospectively identified and followed up independently for a mean of 10.3 years (5.3 to 16.6).

At ten years, the mean Oxford Knee Score was 40 (standard deviation (sd) 9; 2 to 48): 79% of knees (349) had an excellent or good outcome. There were 52 implant-related re-operations at a mean of 5.5 years (0.2 to 14.7). The most common reasons for re-operation were arthritis in the lateral compartment (2.5%, 25 knees), bearing dislocation (0.7%, seven knees) and unexplained pain (0.7%, seven knees). When all implant-related re-operations were considered as failures, the ten-year rate of survival was 94% (95% confidence interval (CI) 92 to 96) and the 15-year survival rate 91% (CI 83 to 98). When failure of the implant was the endpoint the 15-year survival was 99% (CI 96 to 100).

This is the only large series of minimally invasive UKAs with 15-year survival data. The results support the continued use of minimally invasive UKA for the recommended indications.

Cite this article: Bone Joint J 2015;97-B:1493–99.


The Bone & Joint Journal
Vol. 96-B, Issue 1 | Pages 59 - 64
1 Jan 2014
Weston-Simons JS Pandit H Kendrick BJL Jenkins C Barker K Dodd CAF Murray DW

Mobile-bearing unicompartmental knee replacements (UKRs) with a flat tibial plateau have not performed well in the lateral compartment, owing to a high dislocation rate. This led to the development of the Domed Lateral Oxford UKR (Domed OUKR) with a biconcave bearing. The aim of this study was to assess the survival and clinical outcomes of the Domed OUKR in a large patient cohort in the medium term. We prospectively evaluated 265 consecutive knees with isolated disease of the lateral compartment and a mean age at surgery of 64 years (32 to 90). At a mean follow-up of four years (. sd. 2.2, (0.5 to 8.3)) the mean Oxford knee score was 40 out of 48 (. sd. 7.4). A total of 12 knees (4.5%) had re-operations, of which four (1.5%) were for dislocation. All dislocations occurred in the first two years. Two (0.8%) were secondary to significant trauma that resulted in ruptured ligaments, and two (0.8%) were spontaneous. In four patients (1.5%) the UKR was converted to a primary TKR. Survival at eight years, with failure defined as any revision, was 92.1% (95% confidence interval 81.3 to 100). . The Domed Lateral OUKR gives good clinical outcomes, low re-operation and revision rates and a low dislocation rate in patients with isolated lateral compartmental disease, in the hands of the designer surgeons. Cite this article: Bone Joint J 2014;96-B:59–64


The Bone & Joint Journal
Vol. 95-B, Issue 4 | Pages 436 - 444
1 Apr 2013
Scott CEH Nutton RW Biant LC

The lateral compartment is predominantly affected in approximately 10% of patients with osteoarthritis of the knee. The anatomy, kinematics and loading during movement differ considerably between medial and lateral compartments of the knee. This in the main explains the relative protection of the lateral compartment compared with the medial compartment in the development of osteoarthritis. The aetiology of lateral compartment osteoarthritis can be idiopathic, usually affecting the femur, or secondary to trauma commonly affecting the tibia. Surgical management of lateral compartment osteoarthritis can include osteotomy, unicompartmental knee replacement and total knee replacement. This review discusses the biomechanics, pathogenesis and development of lateral compartment osteoarthritis and its management.

Cite this article: Bone Joint J 2013;95-B:436–44.


The Bone & Joint Journal
Vol. 95-B, Issue 2 | Pages 181 - 187
1 Feb 2013
Liddle AD Pandit H O’Brien S Doran E Penny ID Hooper GJ Burn PJ Dodd CAF Beverland DE Maxwell AR Murray DW

The Cementless Oxford Unicompartmental Knee Replacement (OUKR) was developed to address problems related to cementation, and has been demonstrated in a randomised study to have similar clinical outcomes with fewer radiolucencies than observed with the cemented device. However, before its widespread use it is necessary to clarify contraindications and assess the complications. This requires a larger study than any previously published.

We present a prospective multicentre series of 1000 cementless OUKRs in 881 patients at a minimum follow-up of one year. All patients had radiological assessment aligned to the bone–implant interfaces and clinical scores. Analysis was performed at a mean of 38.2 months (19 to 88) following surgery. A total of 17 patients died (comprising 19 knees (1.9%)), none as a result of surgery; there were no tibial or femoral loosenings. A total of 19 knees (1.9%) had significant implant-related complications or required revision. Implant survival at six years was 97.2%, and there was a partial radiolucency at the bone–implant interface in 72 knees (8.9%), with no complete radiolucencies. There was no significant increase in complication rate compared with cemented fixation (p = 0.87), and no specific contraindications to cementless fixation were identified.

Cementless OUKR appears to be safe and reproducible in patients with end-stage anteromedial osteoarthritis of the knee, with radiological evidence of improved fixation compared with previous reports using cemented fixation.

Cite this article: Bone Joint J 2013;95-B:181–7.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 76 - 76
1 Jan 2013
Baker P Jameson S Deehan D Gregg P Porter M Tucker K
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Background. Current analysis of unicondylar knee replacements (UKR) by national registries is based on the pooled results of medial and lateral implants. Using data from the National Joint Registry for England and Wales (NJR) we aimed to determine the proportion of lateral UKR implanted, their survival and reason for failure in comparison to medial UKR. Methods. By combining information on the side of operation with component details held on the NJR we were able to determine implant laterality (medial vs. lateral) for 32,847 of the 35,624 (92%) UKR registered before December 2010. Kaplan Meier plots, Life tables and Cox' proportion hazards were used to compare the risk of failure for lateral and medial UKRs after adjustment for patient and implant covariates. Results. 2,052 (6%) UKR were inserted on the lateral side of the knee. The rates of survival at 5 years were 93.1% (95%CI 92.7 to 93.5) for medial and 93.0% (95%CI 91.1% to 94.9%) for lateral replacements (p=0.49). The rates of failure remained equivalent after adjustment for patient age, gender, ASA grade, indication for surgery and implant type using Cox's proportional hazards (HR=0.87, 95%CI 0.68 to 1.10, p=0.24). For medial implants covariates found to influence the risk of failure were patient age (p< 0.001) and ASA grade (p=0.04). Age similarly influenced the risk of failure for lateral UKRs. Implant design (Mobile versus Fixed bearing) did not influence the risk of failure in either the medial or lateral compartment. Aseptic loosening/lysis and unexplained pain were the main reasons for revision in both groups. Conclusion. The mid-term survival of medial and lateral UKRs are equivalent. This supports the on-going use of pooled data by registries for the reporting on unicondylar outcomes in the future


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 12 | Pages 1641 - 1648
1 Dec 2012
Baker PN Jameson SS Deehan DJ Gregg PJ Porter M Tucker K

Current analysis of unicondylar knee replacements (UKRs) by national registries is based on the pooled results of medial and lateral implants. Consequently, little is known about the differential performance of medial and lateral replacements and the influence of each implant type within these pooled analyses. Using data from the National Joint Registry for England and Wales (NJR) we aimed to determine the proportion of UKRs implanted on the lateral side of the knee, and their survival and reason for failure compared with medial UKRs. By combining information on the side of operation with component details held on the NJR, we were able to determine implant laterality (medial versus lateral) for 32 847 of the 35 624 unicondylar replacements (92%) registered before December 2010. Of these, 2052 (6%) were inserted on the lateral side of the knee. The rates of survival at five years were 93.1% (95% confidence interval (CI) 92.7 to 93.5) for medial and 93.0% (95% CI 91.1 to 94.9) for lateral UKRs (p = 0.49). The rates of failure remained equivalent after adjusting for patient age, gender, American Society of Anesthesiologists (ASA) grade, indication for surgery and implant design using Cox’s proportional hazards method (hazard ratio for lateral relative to medial replacement = 0.88 (95% CI 0.69 to 1.13); p = 0.32). Aseptic loosening/lysis and unexplained pain were the main reasons for revision in both groups, although the reasons did vary depending on whether a mobile- or a fixed-bearing design was used. At a maximum of eight years the mid-term survival rates of medial and lateral UKRs are similar.


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 10 | Pages 1356 - 1361
1 Oct 2012
Streit MR Walker T Bruckner T Merle C Kretzer JP Clarius M Aldinger PR Gotterbarm T

The Oxford mobile-bearing unicompartmental knee replacement (UKR) is an effective and safe treatment for osteoarthritis of the medial compartment. The results in the lateral compartment have been disappointing due to a high early rate of dislocation of the bearing. A series using a newly designed domed tibial component is reported.

The first 50 consecutive domed lateral Oxford UKRs in 50 patients with a mean follow-up of three years (2.0 to 4.3) were included. Clinical scores were obtained prospectively and Kaplan-Meier survival analysis was performed for different endpoints. Radiological variables related to the position and alignment of the components were measured.

One patient died and none was lost to follow-up. The cumulative incidence of dislocation was 6.2% (95% confidence interval (CI) 2.0 to 17.9) at three years. Survival using revision for any reason and aseptic revision was 94% (95% CI 82 to 98) and 96% (95% CI 85 to 99) at three years, respectively. Outcome scores, visual analogue scale for pain and maximum knee flexion showed a significant improvement (p < 0.001). The mean Oxford knee score was 43 (sd 5.3), the mean Objective American Knee Society score was 91 (sd 13.9) and the mean Functional American Knee Society score was 90 (sd 17.5). The mean maximum flexion was 127° (90° to 145°). Significant elevation of the lateral joint line as measured by the proximal tibial varus angle (p = 0.04) was evident in the dislocation group when compared with the non-dislocation group.

Clinical results are excellent and short-term survival has improved when compared with earlier series. The risk of dislocation remains higher using a mobile-bearing UKR in the lateral compartment when compared with the medial compartment. Patients should be informed about this complication. To avoid dislocations, care must be taken not to elevate the lateral joint line.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 29 - 29
1 Jul 2012
Parwez T Hassaballa M Artz N Robinson J Murray J Porteous A Newman J
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Purpose. The aim of this study was to compare the short-term and mid-term outcome of lateral UKRs using a single prosthesis, the AMC Uniglide knee implant. Methods. Between 2003 and 2010, seventy lateral unicompartmental knee replacements (mean patient age 63.6±12.7 years) were performed at our unit for isolated lateral compartmental disease. Range of knee motion and functional outcome measures including the American Knee Society (AKSS), Oxford (OKS) and WOMAC scores were recorded from 19 knees at five years' post-operatively and compared to 35 knees at two-years and 53 knees at one-year post-op. Results. Mean range of motion at five-years post-op was 116° compared to 117° at two-years and 115° at one-year. Median AKSS was 177, 185 and 180 at 1, 2, and 5 years post-op with respective OKS of 39, 43, and 37. Total WOMAC scores were 19, 15 and 22 at 1, 2 and 5 years respectively. One-way ANOVA showed no significant decline in range of motion or functional outcome scores with increasing time since surgery (p>0.05). No lateral UKR required revision up to 5 years post-op. Conclusion. This study demonstrates that at five years' post-op, patients who have undergone a lateral compartmental knee replacement for lateral compartment osteoarthritis using this prosthesis maintain an acceptable range of knee motion and knee function. Revision rates for the lateral UKR were excellent at 5 years following surgery. The lateral fixed bearing UKR demonstrates good short and medium term results for treating isolated lateral compartmental osteoarthritis and should be a consideration when managing patients with a pattern of lateral compartment disease


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 203 - 203
1 Jun 2012
Schelfaut S
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Introduction. Despite the theoretical advantages of mobile bearings for lateral unicompartmental knee replacement (UKR), the failure rate in the initial published series of the lateral Oxford UKR's was unacceptably high. The main cause of failure was early dislocation. In contrast, dislocations of bearings in medial UKR's are rare. The lateral compartment present a higher laxity in flexion than the medial. An adaptation of the lateral design by introducing a convex tibial component and biconcave bearing should tackle this difference in kinematics. The risk of dislocation increased substantially if the lateral tibial joint line was elevated, quantified by the proximal tibial varus angle. This angle had a significant relationship to dislocation. A recent kinematic study identified roughly 3 times as much posterior translation of the tibia during deep knee bend activities after lateral UKR compared to the normal knee, possibly also resulting in a higher incidence of bearing dislocation. With the exception of dislocation, the overall early complication ratio in the initial published series of lateral Oxford UKR was also rather high compared to the last published series. Is there a learning curve?. Materials and Methods. Between January 2009 and April 2010, 16 domed lateral Oxford unicompartmental knee replacements were implanted by the senior author. The valgus deformity was in 2 cases not completely correctable. All femoral components were positioned anatomically. In no case the popliteus tendon was divided. A partial iliotibial band (ITB) release was done in 2 cases. The most common tracking deviation of the bearing peroperatively was a small lift off in deep flexion, seen in 6 cases. Results. Dislocation: no. Clinical outcome. Twelve of our patients (75%) have already good or excellent results with no pain in rest, no or mild pain with activity and good restoration of function. One patient feels some pain in deep flexion during work as a carpenter. In only one patient there is still a flexion of less than 100°. Small extension deficits are seen in 4 patients. Radiographic outcome. The full-leg radiographs showed a valgus axis of 1,2° (-1° to 7°) compared to preoperative 5,8° (0° to 14°). The assessment of the proximal tibial varus angle resulted in an angle of 3,8° (1 to 7°). The measurements on deep flexion radiographs are not yet available. Discussion and Conclusion. Until now we had no dislocation of the bearing in our series, but further follow-up is needed. The preliminary clinical results are already promising and display no early complications needing further operations. By anatomical placement of the femoral component the height of the lateral joint line seems to be respected, confirmed by a nearly correct proximal tibial varus angle in all cases. An increased proximal tibial varus angle can also be avoided by minimizing damage to the lateral soft tissues during surgery and so not over-tighten the knee. Therefore the popliteus tendon should stay intact. The elevated posterior translation, as seen in the recent kinematic studies of the lateral Oxford UKP can perhaps also be reduced by respecting those soft tissues


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XVIII | Pages 59 - 59
1 May 2012
Simpson DJ Kendrick B Thomas G Gill H O'Connor J Murray DW
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Introduction. The results of the original mobile bearing Oxford unicompartmental knee replacement (UKR) in the lateral compartment have been disappointing because of high dislocation rates (11%). This original implant used a flat bearing articulation on the tibial tray. To address the issue of dislocation a new implant (domed tibia with biconcave bearing to increase entrapment) was introduced with a modified surgical technique. The aim of this study was to compare the risk of dislocation between a domed and flat lateral UKR. Methods. Separate geometric computer models of an Oxford mobile bearing lateral UKR were generated for the two types of articulation between the tibial component and the meniscal bearing: Flat-on-flat (flat) and Concave-on-convex (domed). Each type of mobile bearing was used to investigate three distinct dislocation modes observed clinically: lateral to medial dislocation, with the bearing resting on the tray wall (L-M-Wall); medial to lateral dislocation, out of the joint space (M-L); anterior to posterior dislocation, out of the joint space (A-P). A size C tray and a medium femoral component and bearing were used in all models. The femoral component, tibial tray and bearing were first aligned in a neutral position. For each dislocation the tibial tray was restrained in all degrees of freedom. The femoral component was restrained from moving in the anterior-posterior directions and in the medial-lateral directions. The femoral component was also restrained from rotating about the anterior-posterior, medial-lateral and superior-inferior directions. This meant that the femoral component was only able to move in the superior-inferior direction. Different bearing sizes were inserted into the model and the effect that moving the femoral component medially and laterally had on the amount of distraction required to cause bearing dislocation was investigated. Results. The average femur distraction to allow bearing dislocation in the A-P, M-L and L-M-wall directions was 1.62 mm (27%), 0.51 mm (26%) and 1.2 mm (24%) greater respectively for the domed bearing. There was a 3% increase in femoral distraction required to cause L-M-Wall dislocation, per increment of bearing thickness for both the domed and lateral bearings. There was on average a 7% increase in femoral distraction required to cause L-M-Wall dislocation per mm increment of medial femoral component movement. Discussion. Dislocation over the tray wall is a particular clinical problem and using a domed bearing can lead to an increased required femoral distraction of between 25% and 37%. This may be significant during everyday activities and demonstrates that the new domed design should reduce the incidence of bearing dislocation by increasing the amount of entrapment. Increasing the thickness of the bearing has a small effect on the distraction required to allow bearing dislocation. Lateral placement of the femoral component markedly reduced the femoral distraction required for bearing dislocation over the tray wall. Medial placement of the femoral component is advisable so long as impingement with the tray wall is avoided


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XII | Pages 5 - 5
1 Apr 2012
Wakeling C Bracey D
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The Oxford unicompartmental knee replacement (UKR) was introduced in 1976 with good results. Mobile bearings in the lateral compartment have been associated with unacceptably high bearing dislocation rates, due to greater movement between the lateral femoral condyle and tibia, and the lateral collateral ligament's laxity in flexion. The new domed implant is designed to counter this with a convex tibial prosthesis and a fully-congruent, bi-concave mobile bearing allowing a full range-of-movement (ROM), minimising dislocation risk and bearing wear. We present complication rates and clinical outcomes for a consecutive series of our first 20 patients undergoing Oxford domed lateral UKR, between June 2006 and August 2009, with minimum 6-month follow-up. There was one unrelated death (31 months post-UKR) and one postop MI. We had no bearing dislocations, infections or loosening nor other complications. All patients had post-op Oxford Knee Scores; eleven had pre-op scores and demonstrated a significant improvement – mean pre-op 22.75 to post-op 35.45 (p=0.01). All achieved full extension with average ROM 116°, mean change in ROM was –2.6°(p=0.6). This study adds to previous work in confirming a low level of complications with this new procedure (including the early learning curve), particularly bearing dislocation and demonstrates excellent functional outcomes


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 25 - 25
1 Mar 2012
Pandit H Jenkins C Gill H Beard D Price A Dodd C Murray D
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Introduction. The results of the mobile bearing Oxford unicompartmental knee replacement (UKR) in the lateral compartment have been disappointing with a five year survival of 82%. Therefore, it is recommended that mobile bearings should not be used for lateral UKR. This low survivorship is primarily due to high dislocation rate, all occurring in the first year. A detailed analysis of the causes of bearing dislocation confirmed the elevated lateral tibial joint line to be a contributory factor. A new surgical technique was therefore introduced in which care was taken neither to remove too much bone from distal femur nor to over tighten the knee and thus ensure that the tibial joint line was not elevated. Other modifications to the technique were also introduced including use of a domed tibial component. Aim. The aim of this study is to compare the outcome of these iterations: the original series [series I], Series II with improved surgical technique and the domed tibial component [Series III]. Method. The primary assessment of outcome was bearing dislocation at one year. One year was chosen as all the dislocations in the first series occurred within a year. In series I, there were 53 knees, in series II 65 knees and in series III 100 knees, all with a minimum of one year follow up. Results. In series I, there were 6 bearing dislocations (11%) and the average range of movement (ROM) was 110°. In the second series, there were 2 dislocations (3%) and the average ROM was 118°. In the third series, there were no primary dislocations and the average ROM was 125°, the difference between range of movement as well as dislocation rate being significant. Conclusions. The improved surgical technique and implant design have reduced the dislocation rate to an acceptable level and therefore a mobile bearing can now be recommended for lateral UKR


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 2 | Pages 198 - 204
1 Feb 2011
Pandit H Jenkins C Gill HS Barker K Dodd CAF Murray DW

This prospective study describes the outcome of the first 1000 phase 3 Oxford medial unicompartmental knee replacements (UKRs) implanted using a minimally invasive surgical approach for the recommended indications by two surgeons and followed up independently. The mean follow-up was 5.6 years (1 to 11) with 547 knees having a minimum follow-up of five years. At five years their mean Oxford knee score was 41.3 (sd 7.2), the mean American Knee Society Objective Score 86.4 (sd 13.4), mean American Knee Society Functional Score 86.1 (sd 16.6), mean Tegner activity score 2.8 (sd 1.1). For the entire cohort, the mean maximum flexion was 130° at the time of final review.

The incidence of implant-related re-operations was 2.9%; of these 29 re-operations two were revisions requiring revision knee replacement components with stems and wedges, 17 were conversions to a primary total knee replacement, six were open reductions for dislocation of the bearing, three were secondary lateral UKRs and one was revision of a tibial component. The most common reason for further surgical intervention was progression of arthritis in the lateral compartment (0.9%), followed by dislocation of the bearing (0.6%) and revision for unexplained pain (0.6%). If all implant-related re-operations are considered failures, the ten-year survival rate was 96% (95% confidence interval, 92.5 to 99.5). If only revisions requiring revision components are considered failures the ten-year survival rate is 99.8% (confidence interval 99 to 100).

This is the largest published series of UKRs implanted through a minimally invasive surgical approach and with ten-year survival data. The survival rates are similar to those obtained with a standard open approach whereas the function is better. This demonstrates the effectiveness and safety of a minimally invasive surgical approach for implanting the Oxford UKR.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 19 - 19
1 Jan 2011
Pandit H Jenkins C Beard D Gill H Price A Dodd C Murray D
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The results of mobile bearing Oxford unicompartmental knee replacement (UKR) in the lateral compartment have been disappointing (five-year survival: 82%). Therefore, it is recommended that mobile bearings should not be used for lateral UKR. This low survivorship is primarily due to a high dislocation rate. A detailed analysis confirmed the elevated lateral tibial joint line to be a contributory factor to bearing dislocation. A new surgical technique was therefore introduced in which care was taken neither to remove too much bone from the distal femur nor to over tighten the knee and therefore ensure that the tibial joint line was not elevated. Other modifications included use of a domed tibial component. The aim of this study is to compare the outcome of these iterations: the original series (series I), those with improved surgical technique (series II) and the domed tibial component (series III). The primary outcome measure was bearing dislocation at one year. One year was chosen as all the dislocations in the first series occurred within a year. In the original series (n=53), implanted using a standard open approach, there were six dislocations in the first year, the average flexion 110°, and 95% had no/mild pain on activity. In the second series (n=65), there were 3 dislocations, the average flexion was 117°, and 80% had no/mild pain on activity. In the third series with the modified technique and a convex domed tibial plateau, there was one dislocation, average flexion was 125° and 94% had no/mild pain on activity. At four years the cumulative primary dislocation rates were 10%, 5% and 0% respectively, and were significantly different (p=0.04). The improved surgical technique and implant design has reduced dislocation rate to an acceptable level so a mobile bearing can now be recommended for lateral UKR


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 541 - 541
1 Oct 2010
Newman J Robinson J
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Background: Although many knee surgeons routinely perform unicompartmental replacement (UKR) for medial compartment arthrosis there is still reluctance to perform lateral UKR’s as they are generally thought to be less satisfactory. The purpose of the present study was to prospectively compare the outcome of lateral UKR’s with medial UKR’s using the AMC Uniglide knee implant. Methods: Between 2002 and 2005, 29 lateral fixed bearing AMC Uniglide UKR’s were performed at our unit. American Knee Society (AKS), Oxford and WOMAC scores were recorded pre-operatively and at two years post-op and compared with the results of 50 medial mobile bearing and 50 medial fixed bearing AMC Uni-glide UKR’s performed during the same time period. Data was acquired by a research nurse and recorded prospectively on the Bristol Knee Database. The mean ages of the patients were: 63 years in the lateral UKR group was, 62 years in the medial mobile bearing group and 69 in the medial fixed bearing group. The groups were equally sex matched with a predominate number of females in each group. There was no difference between the pre-operative scores for the 3 groups. Results: At one-year review, the 3 groups had similar mean scores: (table removed). Conclusions: This study suggests that at two years the quality of outcome of Lateral UKR’s is at least equivalent to both fixed and mobile bearing medial compartment UKR’s. However, continued long-term survivorship studies are needed to assess failure rates of Lateral fixed bearing UKR’s and particularly to evaluate progression of arthritis in the medial compartment. The procedure should form part of the knee surgeons’ armamentarium, but the differences in the operative techniques for lateral and medial UKR must be appreciated


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 412 - 412
1 Sep 2009
Pandit H Jenkins C Gill H Beard D Marks B Price A Dodd C Murray D
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Introduction: The results of the mobile bearing Oxford unicompartmental knee replacement (UKR) in the lateral compartment have been disappointing with a five year survival of 82%. Therefore, it is recommended that mobile bearings should not be used for lateral UKR. This low survivorship is primarily due to high dislocation rate, all occurring in the first year. A detailed analysis of the causes of bearing dislocation confirmed the elevated lateral tibial joint line to be a contributory factor. A new surgical technique was therefore introduced in which care was taken neither to remove too much bone from the distal femur nor to over tighten the knee and therefore ensure that the tibial joint line was not elevated. Other modifications to the technique were also introduced including use of a domed tibial component. Aim: The aim of this study is to compare the outcome of these iterations: the original series [series I], Series II with improved surgical technique and the domed tibial component [Series III]. Method: The primary assessment of outcome was bearing dislocation at one year. One year was chosen as all the dislocations in the first series occurred within a year. In series I, there were 53 knees, in series II 65 knees and in series III 60 knees, all with a minimum of one year follow up. Results: In series I, there were 6 bearing dislocations (11%) and the average range of movement (ROM) was 110°. In the second series, there were 2 dislocations (3%) and the average ROM was 118°. In the third series, there were no primary dislocations and the average ROM was 125°. Conclusions: The improved surgical technique and implant design has reduced the dislocation rate to an acceptable level so a mobile bearing can now be recommended for lateral UKR


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 47 - 48
1 Mar 2009
van Duren B Gallagher J Pandit H Beard D Dodd C Gill H Murray D
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Introduction: The Oxford unicompartmental knee replacement (UKR) use in the lateral compartment has been associated with a reduced flexion range and increased medial compartment pain than seen with its medial counterpart due to, in part, the inadequacy of a flat tibial tray replacing the domed anatomy of the lateral tibia. A new design incorporating a domed tibial component and a biconcave meniscal bearing has been developed to overcome these problems. This study reports a clinical comparison of new and old establishing whether this modified implant has maintained the established normal kinematic profile of the Oxford UKR. Method: Patients undergoing lateral UKR for OA were recruited for the study. Fifty one patients who underwent UKR with the domed design were compared to 60 patients who had lateral UKR with a flat inferior bearing surface. Kinematic evaluation was performed on 3 equal subgroups (n = 20); Group 1-Normal volunteer knees, Group 2-Flat Oxford Lateral UKR’s and Group 3-Domed Oxford Lateral UKR’s. The sagittal plane kinematics of each knee was assessed using videofluoroscopic analysis whilst performing a step up and deep knee bend activity. The fluoroscopic images were recorded digitally, corrected for distortion using a global correction method and analysed using specially developed software to identify the anatomical landmarks needed to determine the Patella Tendon Angle (PTA) (the angle the patella tendon and the tibial axis). Knee kinematics were assessed by analysing the movement of the femur relative to the tibia using the PTA. Results: PTA/KFA values, for both devices, from extension to flexion did not show any significant difference in PTA values in comparison to the normals as measured by a 3-way ANOVA. The Domed implant achieved higher maximal active flexion during the lunge exercise than those with a flat implant. Only 33% of the flat UKR’s achieved KFA of 130° or more under load whilst performing a lunge, compared with 75% of domed UKR’s and 90% of normal knees. No flat UKR achieved a KFA of 140° or more, yet 50% of all domed UKR’s did, as did 60% of all normal knees. Conclusions: There was no significant difference in sagittal plane kinematics of the domed and flat Oxford UKR’s. Both designs had favorable kinematic profiles closely resembling that of the normal knee, suggesting normal function of the cruciate mechanism. The domed knees had a greater range of motion under load compared to the flats, approaching levels seen with the normal knee, suggesting that limited flexion for the flat plateau results from over tightening in high flexion and that this is corrected with the domed plateau. Problems with the second generation of lateral Oxford UKA have been rectified by a new bi-concave bearing without losing bearing stability and normal kinematics