Previous studies revealed the close relation of anxiety and low back pain. Among people with chronic low back pain, anxiety is the most commonly reported mental disorder. Thus, in the literature, there are several studies considering the anxiety as a risk factor for chronic low back pain. The authors also documented a significant differences between sexes in anxiety and quality of life due to low back pain. US National Institute of Mental Health reports that the lifetime prevalence of an anxiety disorder is 60 % higher in women than in men and that the onset, severity, clinical course, and treatment response of anxiety disorders differ significantly in women. In addition, literature has showed that women may have a worse quality of life when they have low back pain. University students may undergo an undue amount of stress, with negative outcomes in terms of academic resuşts and personal, emotional or health, consequences. Moreover, stress can be experienced at different time periods, not only during university life, but also before, during the transition from undergraduate to professional level, and after, during the transition to the life work. After all these literature knowledge, we designed the study to compare the anxiety and quality of life levels of female and male specifically university students with low back pain aged between 18–26. In this study, 100 female and male university students with low back pain aged between 18–26 were included. The low back pain level were measured by Visual Analogue Scale (VAS) and the disability level due to the pain was measured by Revised Oswestry Low Back Pain Disability Questionnaire (ODI). Beck Anxiety Inventory (BAI) was used to evaluate the anxiety level and also, Short Form 36 survey (SF-36) was used to understand the quality of life for subjects. These questionnaires were asked to participants on online platform via Google Forms between March 2020 and May 2020. SPSS Version 25.0 program was used for statistical analyses. The result of the study showed that there was a statistically significant difference between female and male students on anxiety levels (p<0.05). There were no statistically differences between female and male students on ODI and VAS (p>0.05). In female group, BAI and “Physical function” and “General Health” subgroups of SF-36 have negative correlations (p<0.05). When we correlated BAI and all subgroups of SF-36 in male group, the statistical results were showed that negative correlation with all subgroups (p<0.05) except “Energy and Fatigue” subgroup (p>0.05). We conclude that female university students with low back pain have higher anxiety levels than male students. Future studies can work on young students to cope with the psychological problems for well-being

Objectives. This paper describes the outcomes obtained from a 12 hour group based multidisciplinary functional restoration programme for patients with persistent low back pain who presented with psychosocial obstacles to recovery. The programme was designed to address modifiable psychosocial obstacles to recovery over a four week period, reduce pain related disability, improve pain self-efficacy and reduce patients' reliance on analgesic medication. Design. A single group retrospective analysis. Participants. Data from 54 participants with non-specific low back pain (Male = 26. Female =28, mean age 43.7yrs) who attended a four week functional restoration programme between September 2012 and June 2013 were analysed. Results. There was a statistically significant improvement between Oswestry Disability Index and Pain Self Efficacy scores before and after the treatment intervention, and at 9 month follow-up (p<0.001). When only scores at the end of the treatment intervention and month 9 were compared there was no significant difference (p=0.184 for ODI, p=0.341 for PSEQ). Patients also self-reported reduced reliance on analgesic medication after the treatment intervention and at 9 month follow-up. Conclusion. The findings indicate that a group based multidisciplinary functional restoration programme for patients with persistent low back pain, which targets modifiable obstacles to recovery, can be effective in reducing disability, improving self-efficacy and reducing reliance on medication in both the short and medium term. This article has also been published online in Wiley Online Library (. wileyonlinelibrary.com. ) DOI: 10.1002/msc.1078 in Musculoskeletal Care Journal (2014) © 2014 John Wiley & Sons, Ltd. Conflicts of interest: No conflicts of interest. Sources of funding: No funding obtained

Twelve patients presenting with acute low back pain only and demonstrating intensification of low back pain during passive straight leg raising were investigated with CT or MRI scanning. None of these patients had leg pain. The painful and reduced passive SLR was accompanied by further increase in pain on dorsiflexion of the foot and reduction in pain on knee flexion, findings normally associated with sciatic pain due to acute nerve root compression following disc protrusion. Imaging demonstrated significant central disc prolapses at L4/5 or L3/4 in all patients. In those who showed unilateral restriction of passive straight leg raising, the scans revealed central disc protrusions with a disposition to the affected side. None of these patients had neurological deficits effecting the leg, bladder bowels. The clinical presentation, imaging and anatomy of the spinal canal would clearly implicate the anterior dura as being the source of the pain, being compressed by a central disc protrusion. The nerve supply of the anterior dura as opposed to the posterior dura is substantial. The dura as an origin of acute low back pain has received some but not widespread attention in the medical literature. The clinical outcome of these patients typically mimicked those who present with acute sciatica. The majority improved spontaneously and only a small proportion continued to have significant pain some months after the onset of symptoms. Diagnosis of this clinical syndrome, which has not been fully described before, may give some focal point for an explanation of the pain source to the patient and give some lead to further investigations

Study design: Prospective cohort study. Objective: To investigate association between recovery from low back pain (LBP) and body mass index (BMI) in patients with LBP undergoing physiotherapy. Introduction: The relationship between obesity and LBP has long been debated. There are no published studies examining the influence of BMI on recovery from LBP. Methods: One hundred and forty patients with chronic LBP and no neurological deficit underwent a back-specific physiotherapy programme. BMI and recovery parameters such as pain intensity (visual analogue scale scores), and self-experienced impairment and disability scores were measured. The range of motion of the lumber spine was also recorded. These variables were compared pre and post treatment. Statistical analysis was performed using paired t tests, Spearman’s rank correlation coefficients and ANCOVA. Results: Mean age was 38 years (range 18–67) with 62% males and 38% females. The treatment resulted in significant improvements in all the recovery parameters (P < 0.005, paired t test). No significant association was detected between the BMI of subjects and % changes in pain intensity, self-experienced impairment and disability, and range of motion of the lumbar spine. A comparative analysis of the after treatment recovery parameter scores in normal (BMI ≤24.9), overweight (BMI 25–29.9) and obese (BMI ≥ 30) revealed no significant differences in the mean pain intensity and mean self-experienced impairment and disability scores. Conclusion: Although a BMI within normal range is desirable for prevention of many health conditions including LBP, it does not influence the overall recovery from low back pain in patients undergoing physiotherapy treatment

Purpose. Cognitive Muscular Therapy (CMT) is a new treatment for low back pain which integrates psychological techniques for pain management alongside training to improve postural control. Rather than focus on postural alignment or strength, CMT aims to improve the regulation of postural tone (low-level activity which supports the body against gravity). This is achieved by teaching patients an awareness of compensatory paraspinal activation, which can be triggered by overactivity of the abdominal muscles. The aim of this study was to understand whether CMT could reduce symptoms associated with low back pain and improve paraspinal muscle activation. Methods and results. Fifteen patients with chronic low back pain received seven weekly sessions of CMT from a physiotherapist. Clinical data was captured at baseline and two weeks after the intervention using the Roland-Morris questionnaire and the pain catastrophising scale. Activation of the erector spinae muscle during walking was also measured at baseline and after the final intervention session. Change data were analysed using paired t-tests. There was a 75% reduction (p<0.001) in the Roland-Morris score from a mean (SD) of 9.3(2.9) to 2.3(2.6), along with a 78% reduction in pain catastrophising (p<0.002) from 16.6(13) to 3.7(4.8). Activation of the contralateral erector spinae muscles reduced by 30% (p<0.01) during the contralateral swing phase of walking. Conclusion. In this small sample, CMT delivered large clinical improvements and reduced activation of the low back muscles during walking. Larger randomised trials are now required to confirm whether CMT could outperform existing physiotherapy treatments for chronic back pain. Conflict of interest. No conflicts of interest. Source of funding. University of Salford

Aims. 1. To develop a decision aid - Decision Support Package (DSP) - that will provide low back pain (LBP) patients, and their treating physiotherapists with information on the treatment options available to the patients. 2. To develop a training package for physiotherapists on how to use the DSP. 3. To encourage and evaluate the informed shared decision making (ISDM) process between patients and physiotherapists during consultation. Method. We developed a DSP informed by existing research and collaboration with physiotherapists, patients and experts in the field of decision aids and LBP. We did six pieces of exploratory work: literature review; 2009 NICE LBP guidelines review; qualitative screening of transcripts of interviews of LBP patients; focus groups (patients); nominal group (physiotherapists), and Delphi study (experts). We collated these data to develop the DSP. We also developed a training package for physiotherapists. Results. We developed a LBP patient resource for use prior to their first consultation and a training package for physiotherapists. The DSP contained information on acupuncture, structured group exercise, manual therapy and cognitive behavioural approach. LBP patients would expect these treatment options to be offered to them at their initial consultation. The training package for physiotherapists was on DSP use and communication skills during consultation. Conclusion. We have developed an evidence and theory informed Decision Support Package and physiotherapists training. We are currently piloting its use in one NHS Trust prior to running a pilot RCT (N=150) to test is effect on improving patient satisfaction with LBP patients' treatment choices. Conflicts of Interest. None. Source of Funding. National Institute for Health Research- Research for Patient Benefit (NIHR-RfPB). This abstract has not been previously published in whole or substantial part nor has it been presented previously at a national meeting

Purpose and background. Although low back pain (LBP) with leg pain, is considered by most a poor prognostic indicator, it is at the same time believed to have a favourable natural resolution, and is often treated along similar lines to non-specific LBP, in line with current guidelines. It is unclear whether patients with LBP and leg pain are a distinct subgroup that might benefit from early identification and targeted interventions. We set out to investigate the impact of LBP with leg pain on health outcomes and health resources compared with that of LBP alone, and to explore which factors contribute to the observed disability outcomes. Methods. A systematic literature search of all English language peer reviewed publications was conducted using Medline, EMBASE, and CINAHL for the years 1994 to 2009. Results. Of the 89 papers retrieved, 9 were included in the review. The heterogeneity of data allowed only for narrative analysis of findings. All studies reported worsening baseline health status in terms of poorer self-assessment and increasing use of health care the further the radiation of leg pain. Differences in quality of life measures were higher for physical than for mental health dimensions. Pain and disability outcome at follow up assessment appeared to be less favourable in this group than for individuals with LBP alone. Conclusion. LBP with leg pain is associated with poorer health outcomes and increased use of health resources. These findings argue for early identification of these cases by health care professionals and for pursuing effective treatments rather than simply treating similarly to non-specific LBP

Background. Low back pain can lead to neuroplastic changes in the central nervous system, known as nociplastic pain. As nociplastic pain may be provoked by premorbid sensory profiles, such profiles may be prognostic in the development of nociplastic pain over time. Objectives. To investigate whether four sensory profiles are prognostic in the development of symptoms of nociplastic pain in people with acute low back pain. Methods. A longitudinal type 2 prognostic factor research study was performed in accordance with the PROGRESS framework, using a baseline and a follow-up after 12 weeks, between the Adolescent/Adult Sensory Profile and the Central Sensitisation Inventory. Study participants were consecutively included from primary care physiotherapy practices randomly spread throughout the Netherlands. A multivariable regression analysis was performed to adjust sensory profiles by the level of pain, disability, age, and duration of low back pain. Results. After adjustment Low Registration B=0.41, 95%CI (0.37, 0.99), Sensory Seeking B=0.37, 95%CI (0.24, 0.73), Sensory Sensitive B=0.51, 95%CI (0.50, 1.06), Sensation Avoiding B=0.46, 95%CI (0.43, 0.99) were significantly associated with the development of nociplastic pain symptoms. Conclusion. Sensory profiles in people with acute low back pain predict symptoms of nociplastic pain after 12 weeks. Conflict of interest: No conflict of interest. Sources of funding: No funding obtained

Purpose and Background. Patients with low back pain are increasing globally. Physical dysfunction and psychosocial factors such as stress, anxiety, and fear of movement, often referred to as yellow flags, play a role in the persistence of low back pain. What is not known is the extent to which yellow flags are screened for and treatment adjusted accordingly by Physiotherapists in India. The aim was to determine the current knowledge and awareness of physiotherapists in India regarding psychosocial factors for managing patients with low back pain. Methods. Semi-structured interviews gathered data from of six physiotherapists, The interviews were conducted online. The data was transcribed and analysed using thematic analysis. Results. The main finding was that the physiotherapists in India had a limited knowledge regarding psychosocial factors for management of low back pain. They were not supportive of adding yellow flag screening into their routine treatments due to lack of t awareness of such screening tools Physical elements of low back pain were focused on during treatment by the therapists and recommended by management. The physiotherapists noted that high daily patient volume left them with limited time to alter treatment protocols. Conclusion. There appears to be limited information and education delivered to the physiotherapists in India regarding psychosocial factors for managing low back pain. The addition of these factors in the education and treatment protocols could address these important factors when managing patients with low back pain in India. Conflicts of interest: No conflicts of interest. Sources of funding: No funding obtained

Purpose. Clinical guidelines identify a clear role for managing back pain with structured exercise. Pilates is a commonly recommended modality, however, Pilates-specific research is limited. Research suggests the patient-practitioner relationship may be important in managing persistent low back pain, although further research is needed to evaluate its impact on outcomes. The purpose of this study was to identify the components of the relationship between Pilates teachers and clients with persistent low back pain. Methods and Results. This qualitative study used a multi-site, ethnographically-informed methodology. Data collection included observation of 24 Pilates sessions at eight sites across the South of England, and 19 semi-structured interviews with Pilates teachers and clients with persistent low back pain. Data were audio-recorded, transcribed verbatim and analysed thematically. From the interviews and observations, ten themes emerged, of which four related to components of the relationship: (1) ‘being known’; (2) support; (3) teacher expertise; and (4) mastery of exercises, facilitated by the teacher. Key influences on the relationship were identified in four themes: (5) professional identity of Pilates teachers; (6) health perceptions; (7) social influences such as group dynamic; and (8) service perceptions. An additional two themes described the perceived impact of the relationship: (9) feelings of safety; and (10) ‘feeling good’. Conclusion. These findings demonstrate the complex, multi-faceted interaction that occurs during Pilates sessions that includes instruction, demonstration, verbal and tactile feedback. This study illustrates the perceived importance of Pilates teachers in providing a safe environment for clients with persistent low back pain to exercise. No conflicts of interest. No funding obtained

In the last decades, the use of artificial intelligence (AI) has been increasingly investigated in intervertebral disc degeneration (IDD) and chronic low back pain (LBP) research. To date, several AI-based cutting-edge technologies, such as computer vision, computer-assisted diagnosis, decision support system and natural language processing have been utilized to optimize LBP prevention, diagnosis, and treatment. This talk will provide an outline on contemporary AI applications to IDD and LBP research, with a particular attention towards actual knowledge gaps and promising innovative tools

Introduction: Low back pain (LBP) is a common symptom in Australian adults. In any 6-month period approximately 10% of Australian adults suffer some significant disability from low back pain. 1. One way of assessing the impact of LBP on a population is to estimate the economic costs associated with the disorder. This method is usually known as a “Cost-of-Illness” or an “Economic Burden” study. 2. The economic burden of disease is often divided into direct and indirect costs and is most often calculated using the Human Capital Method. 2. According to this method the direct costs are represented by the dollar value of the interventions required for diagnosis, treatment and rehabilitation of the disease and the indirect costs by valuing the loss of productivity due to morbidity and mortality. 2,. 3. We estimated the economic burden of LBP in Australian adults. Methods: Data sources used in this study were the 2001 Australian adult low back pain prevalence survey. 1. and a multiplicity of Commonwealth, State and Private Health instrumentalities. Using the Human Capital Method direct costs were estimated on the basis of market prices (charges) and the indirect costs by valuing the loss of productivity due to morbidity. The conservative Friction Cost Method for calculating indirect costs was also used as a comparison. 4. A sensitivity analysis was undertaken where unit prices and volume for a range of services were varied over a feasible range (10%) to review the consequent change in overall costs. Results: We estimated the direct cost of low back pain in 2001 to be AUD$1.02 Billion. Approximately 71% of this amount is for treatment by chiropractors, general practitioners, massage therapists, physiotherapists and acupuncture. However, the direct costs are minor compared to the indirect costs of AUD$8.15 Billion giving a total cost of AUD$9.17 Billion. The sensitivity analysis showed very little change in results. Discussion: The economic burden of low back pain in Australian adults represents a massive health problem. This burden is so great that it has compelling and urgent ramifications for health policy, planning and research. This study identifies that research should concentrate on the reduction of indirect costs. This is not to suggest excluding direct cost research, as it is likely that early, efficient and evidence-based management of low back pain in the first instance may lessen the indirect costs that often follow. These startling results advocate urgent Government attention to LBP as a disorder

INTRODUCTION: Low back pain (LBP) is a common symptom in Australian adults. In any six months period approximately 10% of Australian adults suffer some significant disability from low back pain. 1. One way of assessing the impact of LBP on a population is to estimate the economic costs associated with the disorder. This method is usually known as a “Cost-of-Illness” or an “Economic Burden” study. 2. The economic burden of disease is often divided into direct and indirect costs and is most often calculated using the Human Capital Method2. According to this method the direct costs are represented by the dollar value of the interventions required for diagnosis, treatment and rehabilitation of the disease and the indirect costs by valuing the loss of productivity due to morbidity and mortality. 2,. 3. We estimated the economic burden of LBP in Australian adults. METHODS: Data sources used in this study were the 2001 Australian adult low back pain prevalence survey. 1. and a multiplicity of Commonwealth, State and Private Health instrumentalities. Using the Human Capital Method direct costs were estimated on the basis of market prices (charges) and the indirect costs by valuing the loss of productivity due to morbidity. The conservative Friction Cost Method for calculating indirect costs was also used as a comparison. 4. A sensitivity analysis was undertaken where unit prices and volume for a range of services were varied over a feasible range (10%) to review the consequent change in overall costs. RESULTS: We estimated the direct cost of low back pain in 2001 to be AUD$1.02 Billion. Approximately 71% of this amount is for treatment by chiropractors, general practitioners, massage therapists, physiotherapists and acupuncture. However, the direct costs are minor compared to the indirect costs of AUD$8.15 Billion giving a total cost of AUD$9.17 Billion. The sensitivity analysis showed very little change in results. DISCUSSION: The economic burden of low back pain in Australian adults represents a massive health problem. This burden is so great that it has compelling and urgent ramifications for health policy, planning and research. This study identifies that research should concentrate on the reduction of indirect costs. This is not to suggest excluding direct cost research, as it is likely that early, efficient and evidence-based management of low back pain in the first instance may lessen the indirect costs that often follow. These startling results advocate urgent Government attention to LBP as a disorder

Low back pain in junior Australian Rules footballers has not been investigated, despite findings that adolescent back pain is a strong predictor for adult back pain. The aim of this study was to determine the prevalence, intensity, quality and frequency of low back pain in junior Australian Rules footballers. A cross-sectional survey of male non-elite junior (n = 60) and elite junior players (n = 102) was conducted along with a convenience sample of non-footballers (school children) (n = 100). Subjects completed a self-reported questionnaire on low back pain incorporating the Quadruple Visual Analogue Scale and McGill Pain Questionnaire (short form), along with additional questions adapted from an Australian epidemiological study. For current, average and best low back pain levels, elite junior players had higher pain levels (p < 0.001), with no difference noted between non-elite juniors and controls for average and best low back pain. For low back pain at worst, there were significant differences in the mean pain cores. The difference between elite juniors and non-elite juniors (p = 0.040) and between elite juniors and controls (p < 0.001) was significant, but not between non-elite juniors and controls. The chance of suffering low back pain increases from 45% for controls, through 55% for non-elite juniors to 66.7% for elite juniors. The chance that a pain sufferer experiences chronic pain is 16% for controls and 41% for non-elite junior and elite junior players. Elite junior players experienced low back pain more frequently (p = 0.002), with no difference in frequency noted between non-elite juniors and controls. Over 25% of elite junior and non-elite junior players reported that back pain impacted their performance some of the time or greater. This study demonstrated that when compared with non-elite junior players and non-footballers of a similar age, elite junior players experience back pain more severely and frequently and have higher prevalence and chronicity rates

Introduction: Delay in active management reduces the prognosis for simple low back pain. The aim of this project was to develop a tool for use in GP surgeries to assist the doctor in his/her diagnosis of lower back pain and allow prompt management with confidence. Methods: Three different systems for the automated diagnosis of low back pain were developed. With each, the patient answered a series of questions presented by the system. Three different strategies were employed, one using variable weighting, one a logic tree and one an inference engine. For the purpose of testing the systems against each other, a database was constructed containing the answers to all possible questions from each system for one hundred patients attending a low back pain clinic. The “true” diagnosis was that made by the treating clinician who saw the patients. The original data contained a number of diagnoses:. Spinal Stenosis (central or lateral). Prolapsed Intervertebral Disc. Other Nerve Root Compression (NRC). Mechanical Back Pain (MBP) with NRC. Pure MBP. For the purpose of the comparison two groups were considered – patients with radicular symptoms (groups 1 to 4) and patients with pure MBP. Conclusions: The different approaches to development showed that a number of factors play a crucial role for the accuracy of the systems, including the number of rules used to try to cover every possibility, the interpretation of the questions by the patients and the weighting and approach taken for the different Certainty Factors. The use of any of these three approaches did not allow the development of a system accurate enough for clinical use and it seems that successful development of such a system might require a wholly different approach

Introduction: Estimates of low back pain prevalence show that low back pain is a common problem particularly in western countries. But the extent to which low back pain causes true disability and not just nuisance pain casts doubt of the utility of these estimates. No studies have been performed in Australia to study both the prevalence and disability associated with low back pain in the population. Accordingly, the objectives of this study were to determine the prevalence ranges and retrospective one year incidence of low back pain together with any related disability in Australian adults. Methods: A survey was mailed to a stratified random sample of 3000 Australian adults selected from the Electoral Roll. There was a 69% response rate. Demographic variables of respondents were compared with those of the Australian population taken from Census data. Selective response bias was investigated using wave analysis. A range of prevalence data were derived as was a disability score using the Chronic Pain Grade Questionnaire. 1. (CPG). The CPG has demonstrated reliability and validity in measuring pain and disability in postal surveys. 2. Prevalence and disability estimates were variously standardised using gender, age and marital status. Results: There was little variation between the sample and the Australian adult population. There was no significant selective response bias found. The sample point prevalence was estimated at 25.5% (95% CI, 23.6–27.5), six-months prevalence was 64.6% (95% CI, 62.6–66.8) and lifetime prevalence was 79.2%, (95% CI, 77.3–80.9). The retrospective one year incidence was 8.0% (95% CI, 6.9–9.3). In the previous six months period 42.6% (95% CI, 40.4–44.8) of the adult population had experienced low intensity pain and low disability from it. Another 10.9% (95% CI, 9.6–12.3) had experienced high intensity pain, but still low disability from this pain. However, 10.5% (95% CI, 9.2–11.9) had experienced high disability low back pain. The mean time-off from usual activities in the past six months for this group was 1.6 months (95% CI, 1.3–1.9), the median was 18 days. There was no gender difference for a high disability rating or time-off. Conclusion: Low back pain is a very common problem in the Australian adult population, yet most of this is low intensity and low disability pain. Nevertheless, over 10% had been disabled by low back pain in the past six months and it required significant time off from usual activities

Purpose and Background. Guidelines recommend biopsychosocial care for chronic, complex musculoskeletal conditions, including non-specific low back pain. The aims were: 1/ to assess how patients with low back pain respond to osteopathic treatment, both before and after an osteopath has completed a Biopsychosocial Pain Management (BPM) course; and 2/ to assess if it is feasible and acceptable for osteopath participants to receive weekly SCED data and use it to guide patient management. Methods and Results. A multiple baseline single case experimental design trial (. clinicaltrials.gov. , on 18/10/2021, ID number NCT05120921) with 11 UK osteopaths was conducted. Patients were randomised to early, middle or late treatment start dates. Statistical analysis assessed the change between baseline, intervention and follow-up periods. Primary outcomes were the Numeric Pain Rating (NPR) and Patient Specific Function Scales (PSFS), measured during the baseline, the 6-week intervention, and during a 12-week follow-up period. At baseline, the osteopaths reported stronger biopsychosocial attitudes to pain, compared to biomedical beliefs (PABS: 34 behavioural scale; 29 biomedical scale). Overall, patient participants showed daily increases in symptoms during the pre-treatment phase (+0.24/day, p<0.001), and daily decreases during treatment (−2.94 over the treatment phase, p<0.001), which continued post-treatment (−3.36 over 12 weeks, p=0.04). Similar improvements were observed for function. Conclusion. Osteopathic care was shown to help patients with persistent low back pain. Patient recruitment was challenging because of the randomisation. With further development, the method shows feasibility as a means of enhancing research activity among practising clinicians. Previous presentations or publications of the work. The protocol was published (. https://doi.org/10.1016/j.ijosm.2023.100660. ) and presented at SBPR in 2022. The results were presented to an osteopathic conference in October 2023. Ethics approval was received from the University College of Osteopathy Research Ethics Committee. Conflicts of interests. Jerry Draper-Rodi receives fees from the sales of the e-learning course on the biopsychosocial management on the UCO CPD platform. Sources of funding. The research was funded by the Osteopathic Foundation

The purpose of this study was to investigate whether patient age of 16 years and under is a valid “red flag” for back pain, by determining how often magnetic resonance imaging (MRI) investigations in these patients demonstrated significant pathology. This was a retrospective review of cases over a five-year period (2008–12). The radiology database was interrogated to identify all patients aged 16 and under who had undergone an MRI scan of their lumbar spine for a primary complaint of low back pain. All emergency and inpatient admissions were excluded from the study. Casenotes of each of these patients were analysed for demographics, clinical features, diagnosis and outcome. After exclusions, 98 eligible cases were identified. The age range of these patients was 2–16 years (mean age 12.63 years). The MRI scan found no abnormalities in 71.4% of cases. In the scans with positive findings, there were 8 cases of spondylolysis, 3 spondylolistheses, 9 cases of disc degeneration and 5 cases of Scheuermann's. Tumour or infection were found in only 3% of cases, (2 cases sacroilitis, 1 sacral chondroblastoma); there had been sacral or sacroiliac tenderness in each of these cases. In keeping with other recent studies, this study shows that the diagnostic yield of MRI in patients under the age of 16 with low back pain is relatively high (28.6%). However, scan findings did not significantly alter management in the vast majority of cases (97%). Serious pathology (infection or tumour) was found in only 3% of cases. We therefore suggest that an age of 16 years or less, in isolation, should not be a “red flag” indicator for low back pain. We do however advise a lower threshold for imaging in patients presenting with sacral region pain and tenderness

Background. Low back pain (LBP) is a major problem across the globe and is the leading cause worldwide of years lost to disability. Self-management is considered an important component the treatment of people with non-specific LBP. However, it seems that the self-management support for people with non-specific LBP provided by physiotherapists can be improved. Moreover, the way exercise therapists (ET) address self-management in practice is unknown. Purpose. To investigate the ideas, opinions and methods used by physiotherapists and ET with regard to self-management and providing self-management support to patients with non-specific LBP. Methods. This study was a qualitative survey. An online questionnaire with open-ended questions was developed. The survey was conducted among physiotherapists and ET working in the Netherlands. Data was analysed using thematic analysis. Results. Respondents considered self-management support an important topic in physiotherapy and exercise therapy for people with non-specific LBP. In the self-management support provided by the respondents, providing information and advice were frequently mentioned. The topics included in the support given by the respondents covered a broad range of important factors. The topics frequently focused on biomechanical factors. Therapists mainly provided patient education rather than self-management support. Moreover, important self-management skills were generally not addressed sufficiently. The majority of respondents had a need with regard to self-management or providing self-management support. These needs include having more knowledge, skills and tools aimed at facilitating self-management. Conclusion. The way physiotherapists and ET address self-management in people with non-specific LBP is not optimal and should be improved. Conflicts of interest: No conflicts of interest. Sources of funding: No funding obtained. Previous publication: This work was published in a scientific journal: Hutting N, Oswald W, Staal JB, Heerkens YF. Self-management support for people with non-specific low back pain: A qualitative survey among physiotherapists and exercise therapists. Musculoskelet Sci Pract. 2020 Dec; 50:102269. doi: 10.1016/j.msksp.2020.102269. This work was never presented at a conference

Low back pain is the primary cause of disability in individuals younger than 50 years. Potential sources of low back pain include the intervertebral disks, facet joints, vertebrae, neural structures, muscles, ligaments, and fascia. Increasing evidence is available as to the importance of cytokines in acute and particular chronic pain. Cytokines can influence transduction, conduction, and transmission of the nociceptive signal, resulting in prolonged or permanent signalling to the brain’s cognitive centres in the absence of a painful noxious or nonnoxius stimulus. Several cytokines, including IL-1, TNFa, IL-6, and IL-10 are thought to influence nociception or pain. To date, there have been no studies of the production of inflammatory mediators in blood from patients with low back pain. We have therefore analysed levels of the proinflammatory mediators IL-1ß, IL-6, TNF-α in sera from patients with sciatica and low back pain, and their possible relationship to pain dimensions. In this prospective longitudinal study with a follow-up of six months, the course of serum concentration of IL-1ß, IL-6 and TNF-α was measured by Bio-Plex cytokine assay in 31 patients with acute sciatica and 41 patients with chronic low back pain. Blood samples were taken at ten fixed times during follow-up, and cytokine values were adjusted to possible influential factors and correlated to the course of pain and clinical function to evaluate the predictive role of cytokine regarding therapy outcome. At admission of the study and 10 days later, the proportion of TNF-α positive subjects was significant elevated among patients with low back pain compared to patients with acute sciatica. Median (SD) of serum TNF-α concentrations were significant higher in patients with chronic low back pain (n=41) than in patients with acute sciatica (n=31). In the whole period the pain of patients reduced from time to time. Elevated TNF-α serum levels are associated with a significantly improved pain in patients with chronic low back pain but not with acute sciatica. A close coherence exists between the cytokines IL-1ß, IL-6 and TNF-α together in blood of patients as with acute sciatica as with chronic low back pain. But no connection of IL-1ß, IL-6 or TNF-α and CRP in blood was observed. Neither age, sex, BMI, nicotine and alcohol consumption are not related to the serum levels of cytokines. As far as we know, this is the first analysis of parameters predicting a major clinical connection of cytokines in blood and low back pain. Our findings indicate that elevated serum levels of the proinflammatory cytokine TNF-α are associated with a significantly improved pain in patients with chronic low back pain but not with acute sciatica. We concluded that Detection of high level of TNF-α might be a marker for more pain in patients with chronic low back pain. and TNF-α probably play an important role in the chronic process of low back pain