Aims. This study aimed to evaluate the BioFire
Aims. Musculoskeletal infection is a devastating complication in both trauma and elective orthopaedic surgeries that can result in significant morbidity. Aim of this study was to assess the effectiveness and complications of local antibiotic impregnated dissolvable synthetic calcium sulphate beads (Stimulan Rapid Cure) in the hands of different surgeons from multiple centres in surgically managed bone and
Aims. This study evaluated the definitions developed by the European Bone and
Acute bone and
Aims. The diagnosis of periprosthetic
Aims. This study aimed to evaluate the clinical application of the PJI-TNM classification for periprosthetic
Aims. Periprosthetic
Aims. Trained immunity confers non-specific protection against various types of infectious diseases, including bone and
Aims. The aims of this study were to determine the incidence and factors for developing periprosthetic
Aims. Body exhaust suits or surgical helmet systems (colloquially, ‘space suits’) are frequently used in many forms of arthroplasty, with the aim of providing personal protection to surgeons and, perhaps, reducing periprosthetic
Antibiotic resistance represents a threat to human health. It has been suggested that by 2050, antibiotic-resistant infections could cause ten million deaths each year. In orthopaedics, many patients undergoing surgery suffer from complications resulting from implant-associated infection. In these circumstances secondary surgery is usually required and chronic and/or relapsing disease may ensue. The development of effective treatments for antibiotic-resistant infections is needed. Recent evidence shows that bacteriophage (phages; viruses that infect bacteria) therapy may represent a viable and successful solution. In this review, a brief description of bone and
Aims. The diagnosis of periprosthetic
Aims. To investigate the optimal thresholds and diagnostic efficacy of commonly used serological and synovial fluid detection indexes for diagnosing periprosthetic
Aims. The management of periprosthetic
Aims. This aim of this study was to analyze the detection rate of rare pathogens in bone and
Aims. We aimed to determine the concentrations of synovial vancomycin and meropenem in patients treated by single-stage revision combined with intra-articular infusion following periprosthetic
Aims. Serum inflammatory parameters are widely used to aid in diagnosing a periprosthetic
Aims. This study aimed to explore the diagnostic value of synovial fluid neutrophil extracellular traps (SF-NETs) in periprosthetic
Aims. It is well described that patients with bone and
Aims. A revision for periprosthetic