Aim

To classify Fracture-related Infection (FRI) allowing comparison of clinical studies and to guide decision-making around the main surgical treatment concepts.

Aim

Duration of perioperative antimicrobial prophylaxis (PAP) remains controversial in prevention of fracture-related infection (FRI) – with rates up to 30% - in open fracture (OF) management. Objectives were to investigate the impact of the PAP duration exclusively in or related to long bone OF trauma patients and the influence of augmented renal clearance (ARC), a known phenomenon in trauma patients, as PAP consists of predominantly renally eliminated antibiotics.

Aim

Infection rates after management of open fractures are still high. Existing guidelines regarding prevention of this complication are inhomogeneous. A survey directed to orthopaedic trauma surgeons worldwide aims to give an overview of current practices in the management of open fractures.

Infection of the ankle joint is a serious problem that can have a debilitating outcome if not identified and treated appropriately.

The purpose of this retrospective study is to present epidemiologic data aimed at better characterising the clinical diagnosis of septic ankle guiding empiric therapy.

All admissions to Los Angeles County+USC Medical Center between 1996 and 2005 were screened to identify patients with ankle infection, shown by a synovial WBC count > 50,000, frank purulence in the joint, or positive synovial culture. Forty-two patients (33 male, 9 female) with a mean age of 44.8 (23 to 67 years) were identified. Twelve out of forty-two patients had indwelling hardware and were excluded from further analysis.

Of the 30 patients with hematogenous septic ankle arthritis, 87% reported ankle pain, 70% ankle swelling, and 50% demonstrated decreased range of motion at the ankle joint. Cultures grew Staphylococcus aureus (43%), streptococci (30%), and gram-negative rods (7%). Twenty-three percent of cases were polymicrobial; no cases of Neisseria gonorrhea were identified. There were 3 cases of M. tuberculosis, and 1 case each of Coccidioides immitis and Aspergillus sp. Forty-four percent of the Staphylococcus aureus were methicillin-resistant (MRSA); no change was observed in prevalence of resistant organisms over time. Only 48% had an elevated WBC count; C-reactive protein and ESR were elevated in 100% of patients. Adjacent osteomyelitis was found in 30% of patients. Open irrigation and debridement was performed in 73% of cases; five patients required multiple surgical procedures and 1 amputation.

Septic ankle arthritis presents non-specifically; a high index of suspicion is essential to ensure prompt identification and treatment. Empiric antibiotic therapy should cover Staphylococcus aureus (including MRSA) and streptococcus. Patients should be evaluated for adjacent osteomyelitis.

Drug injection often results in soft tissue infections of the upper extremity. The purpose of this study was to determine the distinct bacteriologic features of soft tissue abscesses in injecting drug abusers in order to provide guidelines for optimal empiric antibiotic therapy.

Admissions to the musculoskeletal infection ward at our institution from 1993 to 2005 were screened to identify patients with a history of injecting illicit drugs and a diagnosis of a soft tissue abscess. Eight hundred fifty-five patients met these criteria and were included in this retrospective study. There were 638 male and 217 female patients with a mean age of 41.5 years (18 to 75 years).

In the 694 patients with positive cultures the most common organism was Staphylococcus aureus, identified in 359 patients (52%). A progressive increase in the prevalence of ORSA was observed; ORSA comprised 5% of Staphylococcus aureus infections in 1999, 50% in 2001, 56% in 2003, and 82% in 2005. Microaerophilic Streptococcus was present in 37% of culture-positive cases and other anaerobes in 10%. Infections were monomicrobial in 366 of 694 patients (53%) and polymicrobial in 328 of 694 patients (47%).

Staphylococcus aureus is the most common pathogen in soft tissue abscesses in injecting drug abusers with an increasing proportion of ORSA. In addition to surgical decompression of abscesses, broad-spectrum empiric antibiotic therapy may be necessary.

Intramedullary infection is a challenging problem and management usually includes removal of the infected hardware and reaming of the medullary canal.

The purpose of this study is to describe a new technique for canal debridement and evaluate its efficacy in the treatment of posttraumatic osteomyelitis of the tibia and femur.

This retrospective study included 11 patients (10 male and 1 female, mean age: 42 years) with posttraumatic osteomyelitis of the tibia (n=8) or femur (n=3). Surgical treatment consisted of debridement, implant removal, and reaming of the medullary canal with the RIA (Reamer Irrigator Aspirator) device. All procedures were performed by a single surgeon with a standardised technique. Reaming of the canal was performed with one pass of the RIA. Following reaming, the RIA was used for irrigation of the medullary canal with 10 liters of fluid.

At a mean follow-up time of 9 months (6 to 13 months) there was no recurrence of osteomyelitis. Complications included one partial loss of a flap, one refracture of a tibia following an auto versus pedestrian accident, and external fixator pin tract infections in one patient.

The RIA device allows for reaming under simultaneous irrigation and aspiration, which may minimise the residual amount of infected tissue in the medullary canal. The disposable reamer head is always sharp, in contrast to standard reamers, which may reduce the thermal effects of reaming on the adjacent bone. In addition, the RIA allows delivery of fluid throughout the length of the medullary canal, thus facilitating irrigation. The RIA device is useful alternative for debridement of intramedullary infections of the tibia and femur.

The purpose of this study is to present the preliminary results after treatment of shoulder sepsis with prolonged implantation of an antibiotic-loaded cement spacer in a selected group of compromised patients.

The current study included 11 patients (9 males and 2 females) with a mean age of 64 years (range: 36–79 years). All patients were treated with radical debridement, implantation of an antibiotic-impregnated polymethylmethacrylate spacer, and 6 weeks of antibiotic therapy. The subjective complaints, range of motion of the shoulder, functional outcome (mini-DASH score), and radiographic findings were evaluated. Nine patients at a mean follow-up time of 21 months (range: 13–18 months) were free of infection with pain relief and adequate shoulder function for activities of daily living. Radiographic evaluation revealed no loosening or fracture of the spacer and no progressive degenerative changes involving the glenoid.

Prolonged implantation of the spacer may be a useful alternative in selected patients with poor general condition.

Aim of the study: To define the dimensions of the radial head, as well as the radiocapitellar and proximal radio-ulnar joints. The most congruent portions of the radial head articulations were determined.

Materials & Methods: Computed tomography scans of twenty-two cadaveric adult elbows were obtained in three forearm positions – supination, neutral, pronation. The radial head dimensions, the radiocapitellar joints, and the proximal radioulnar joints were also measured. Multivariate analysis of variance was used to determine which portions of each articulation were the most congruent.

Results: At the level of the radial trough, the maximum diameter was 22.3 mm, the minimum diameter was 20.9 mm, and the diameter difference was 1.4 mm. This difference represented only 6.3% of the overall maximum diameter. The depth of curvature of the radial head trough was 2.3 mm, the radial head length was 9.8 mm, and the radial neck length was 10.7 mm. At the isthmus of medullary canal, the maximum diameter was 9.7 mm, the minimum diameter was 8.2 mm, and the diameter difference was 1.5 mm. This difference represented 15.6% of the maximum diameter. The average radiocapitellar distance at the radial lip was 4.0 mm, the trough 2.4 mm, and the ulnar lip 2.2 mm. Thus, the radial head tended to become uncovered at the radial lip (p < 0.0001). The radiocapitellar joint was tighter in pronation than in supination (p = 0.0008). The proximal radioulnar joint was most congruent at the MPRUJ (middle proximal radioulnar joint), at the midportion and posterior aspects, rather than the anterior aspect (p < 0.0001). The PRUJ coverage was between 69.0 and 79.2 degrees.

Conclusions: Prosthesis trial sizing should be judged by the articulations providing the most congruency –

1) the ulnar lip or trough of the radiocapitellar joint in pronation and

Aim: The aim of this prospective study was to evaluate the results of arthroscopic treatment of chondral and osteochondral lesions of the knee with osteochondral autogenous transplantation (OAT). Methods: Thirty patients with symtomatic cartilage lesions of the femoral condyles were treated with OAT. Inclusion criteria were full thickness femoral condyle defects between 1 and 3 cm in diameter. Grafts were harvested from the superior intercondylar notch and press þt into holes drilled into the defect starting adjacent to the articular cartilage margin. All patients were evaluated both pre and postop with the Lysholm score, IKDC Form and radiological assessment. Second look arthroscopy was offered to all patients independently of their symptoms. Results: The mean follow-up was 44.7 months. The mean Lysholm score signiþcantly improved from 43.6 pre-operatively to 87.5 postoperatively (p< 0.001, paired t-test) with excellent and good results in 25 (83.3%) patients. Using the IKDC assessment 26 (86.6%) of the patients reported their knee as being normal or nearly normal. Repeat arthroscopies have been done in 9 (30%) patients. Seven of these demonstrated complete healing and two partial healing. The histological examination ascertained the presence of viable chondrocytes and normal hyaline cartilage in the completely healed cases. Conclusions: Our study suggest that arthroscopic OAT is an effective method for treating chondral defects of the femoral condyles in selected cases. However, further studies with long-term follow-up are needed to determine if the transplanted area will maintain functional and structural integrity over time.