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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLIV | Pages 92 - 92
1 Oct 2012
Windley J Nathwani D
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Unicompartmental knee replacement (UKR) is technically challenging, but has the advantage over total knee replacement (TKR) of conserving bone and ligaments, preserving knee range of movement and stability. Computer navigation allows for accurate placement of the components, important for preventing failures secondary to mal-alignment. Evidence suggests an increase in failure rates beyond 3 degrees of coronal mal-alignment.

Our previous work has shown superior functional scores in those patients having undergone UKR, when compared with those having had TKR. However, to a certain extent, this is likely to be due to differences in the two cohorts. Those selected for UKRs are likely to be younger, with less advanced and less widespread degenerative disease. It is almost inevitable, therefore, that functional outcomes will be superior. We aimed to compare the functional and radiological outcomes of UKR vs TKR in a more matched population.

Ninety-two patients having had one hundred consecutive computer navigated UKRs were reviewed both clinically and radiographically. The Smith & Nephew Accuris fixed-bearing modular prosthesis was used in all cases, with the ‘Brainlab’ navigation system. For our comparative group we identified patients who had actually undergone navigated TKR several years ago, but who, in retrospect, would have now been offered a UKR in line with our current practice. These patients were identified following review of pre-operative radiographs and operation notes, confirming degenerative disease confined mainly to one compartment of the knee, in the absence of any concern as to the integrity of the anterior cruciate ligament. This sub-group of patients were also assessed clinically and radiographically. Mean follow-up for the UKR group was 25 months, (range 8–45.) For our TKR sub-group, nineteen patients were identified. Average length of stay for the UKR group was 3.7 days, (range 2 to 7,) and for the TKR group this was 5.2 days, (range 3 to 10.)

Functional scores (Oxford Knee Score) were good to excellent for the majority of patients in both groups, although they were significantly better in the UKR group. Mean Oxford Knee Score in the UKR group was 7.5, (0–48, with 0 being best.) Mean score in the TKR sub-group was 12.1. (p = 0.02)

Reliably comparing TKR with UKR is difficult, due to the fundamental differences in the two groups. We have endeavoured to match these two cohorts as best possible, in order to compare the outcomes of both. Our use of computer navigation in both groups allows for accurate prosthesis placement. When measuring component position, there were no ‘outliers,’ outside of the widely accepted three degrees of deviation.

We propose that, with the correct patient selection, UKR gives a better functional outcome than TKR. Longer-term follow-up of our UKR group is required to monitor the onset of progressive arthrosis in other joint compartments, although our early results are very encouraging. Furthermore, we advocate the use of computer navigation to firstly allow for more accurate component positioning, and secondly to make challenging UKR surgery less technically demanding.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLIV | Pages 93 - 93
1 Oct 2012
Windley J Ball S Nathwani D
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Computer navigation has the potential to revolutionise orthopaedic surgery, although according to the latest 7th Annual NJR Report, only 2% of the 5 800 unicompartmental knee replacements (UKRs) performed in 2009 were carried out using ‘image guidance.’ The report also states an average 3-year revision rate for UKRs of 6.5%. Previous NJR data has shown that this figure rises up to 12% for certain types of prosthesis. We suspect that a significant proportion of these revisions are due to failure secondary to component malpositioning. We therefore propose that the use of computer navigation enables a more accurate prosthesis placement, leading to a reduction in the revision rate for early failure secondary to component malpositioning. Our early results of one hundred consecutive computer navigated UKRs are presented and discussed.

Ninety-two patients having had one hundred consecutive computer navigated UKRs were reviewed both clinically and radiographically. The Smith & Nephew Accuris fixed-bearing modular prosthesis was used in all cases, with the ‘Brainlab’ navigation system. Pre-operative aim was neutral tibial cut with three degrees posterior slope. Post-operative component alignment was measured with PACs web measuring tools. Patients were scored clinically using the Oxford Knee Score.

Our patient cohort includes 54 male knees and 46 female knees. Average age is 66.6yrs. Average length of stay was 3.7 days, (range 2–7.) With respect to the tibial component, average alignment was 0.7° varus, and 2.32° posterior slope. All components were within the acceptable 3 degrees deviation. Functional scores are very satisfactory, with an overall patient satisfaction rate of 97%.

To date, only one UKR has required revision. This was due to ongoing medial pain due to medial overhang, not related to computer navigation. There was one superficial infection, with full resolution following a superficial surgical washout, debridement and antibiotics. Unlike complications reported in the NJR, we report no peri-prosthetic fractures or patella tendon injuries.

Our results demonstrate accurate prosthesis placement with the use of computer navigation. Furthermore, clinical scores are highly satisfactory. Our current revision rate is 1% at a mean of 27 months post-op. Although longer-term follow-up of our group is required, our results compare very favourably to statistics published in the NJR, (average 3-year revision rate 6.5%.) The only major differences appear to be the type of prosthesis used and the use of computer navigation. It is our proposal that computer navigation reduces the number of revisions required due to component malpositioning and subsequent failure. Furthermore, we believe that this challenging surgery is made easier with the use of computer navigation. We expect our longer-term results to show significant benefits of computer navigation over conventional techniques.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 390 - 390
1 Jul 2011
Ball S Windley J Harnett P Nathwani D
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Computer navigation has the potential to revolutionise orthopaedic surgery. It is widely accepted that component malalignment and malrotation leads to early failure in knee arthroplasty. We aimed to assess the use and reliability of computer navigation in both total (TKR) and unicompartmental (UKR) knee replacement surgery.

We analysed 40 consecutive UKRs and 40 consecutive TKRs. All procedures were carried out with the Brain-LAB navigation system and all were carried out by one consultant orthopaedic surgeon. Preoperative aim was neutral tibial cuts with 3 degrees posterior slope. Coronal and sagittal alignment of tibial components were measured on postoperative radiographs. Patients were also scored clinically with regards to function and pain.

In the TKR group, mean tibial coronal alignment was 0° (range 1 to −2.) Mean sagittal alignment was 2° posterior slope (range 0 to 4.) In the UKR group, mean tibial coronal alignment was 0.55° (range 0 to −3.) Mean sagittal alignment was 2.1° posterior slope (range 0 to 4°.) Clinical outcome scores were very satisfactory for the majority of patients, with far superior functional scores in the UKR group.

Our results demonstrate very accurate placement of the prosthesis in both the TKR and UKR group with computer navigation. There is a very narrow range with no outliers, (all within +/−3 degrees of desired alignment.) Functional outcome scores are good. We advocate the use of computer navigation in unicompartmental as well as total knee replacment surgery, in order to minimise early failures.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 192 - 192
1 May 2011
Akhbari P Ball S Windley J Rajagopal T Nathwani D
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Over 80% of patients are satisfied following total knee arthroplasty (TKA). Female gender was one of the factors found to be a predictor of poorer satisfaction. The landmarks commonly used to achieve correct rotation of the femoral component are the posterior condylar axis, the transepicondylar axes (TEA) & the anteroposterior axis (Whiteside’s line) of the distal femur. The design features of most conventional jig based TKA instrumentation assumes a constant relationship of 3 degrees external rotation between the posterior condylar axis & the epicondylar axis. However during TKA using computer assisted navigation, we observe that these rotational landmarks do not have a constant relationship & there is wide variation among the arthritic population & between the male & female rotational profile. We hypothesise no consistent relationship between the posterior condylar axis, the TEA & the anteroposterior axis of the distal femur.

125 Computerised Tomography (CT) scans of the knee were performed using a 3D helical CT scanner in subjects who did not have any pre-existing clinical & radiological evidence of knee arthritis. CT slices 3 mm in thickness were obtained over the distal femur from the level of the proximal pole of the patella. Standard protocols were established for identifying the bony landmarks & taking measurements. The posterior condylar axis, the TEA & the anteroposterior axis were constructed. The condylar twist angle (CTA), the posterior condy-lar angle (PCA) & the angles made by the TEA & the line perpendicular to the anteroposterior axis were then measured using the PACSWEB digital measurement tools. The data was analysed to determine the consistency of the angular relationship between the reference axes using the STATA data analysis & statistical software. Linear regression was used to investigate any differences in the angle measurements between genders.

125 CT scans of the knee were performed in 111 patients (60 males [65 knees] & 51 females [60 knees]). The mean age was 45 years (SD, 15 years). The results showed no significant difference between the rotational axes of the distal femur between men & women (CTA male(SD): female(SD): 5.9(1.6): 6.3(2.0) [p=0.317], PCA male(SD): female(SD): 2.3(1.5): 2.5(1.9) [p=0.648]). The results also showed it would be inappropriate to assume a constant relationship of 3 degress external rotation between the posterior condylar axis & the epicondylar axes (PCA mean (SD) 2.39(1.70) [p< 0.001], CTA mean (SD) 6.11(1.81) [p< 0.001]).

Our study suggests no significant difference between the rotational reference axes of the distal femur between men & women. Furthermore, most jig-based systems result in 3 degress external rotation of the femoral component. Our results show this is not consistent & may be responsible for the pain in 20% of patients post TKA because of abnormal patellar tracking.