Numerous studies have evidenced cement-in-cement techniques as reliable in revision arthroplasty. The original cement mantle is commonly reshaped to aid accurate placement of the new stem. Ultrasonic devices selectively remove cement, preserve host bone and have lower cortical perforation rates than other techniques. As far as the authors are aware, their impact on final cement-cement bonds has not been investigated. This study assessed the impact of cement removal using OSCAR (Orthosonics System for Cemented Arthroplasty Revision, ORTHOSONICS) on final cement-cement bonds. Twenty-four specimens were manufactured by pouring cement (Simplex P Bone Cement, Stryker) into stainless-steel moulds with a central rod polished to Stryker Exeter V40 specifications. After cement curing, rods were removed and eight specimens allocated to each of three internal surface preparation groups: 1) burr; 2) OSCAR; or 3) no treatment. Internal holes were re-cemented, then each specimen was cut into 5mm discs. Shear testing of discs was completed by a technician blinded to original grouping (Instron 5567, UK), recording ultimate shear strengths. The mean shear strength for OSCAR-prepared specimens (17 MPa, 99% CI 14.9 to 18.6, SD=4.0) was significantly lower than that measured for the control (23 MPa, 99% CI 22.5 to 23.7, SD=1.4) and burr (23 MPa, 99% CI 22.1 to 23.7, SD=1.9) groups (P<0.001, one-way ANOVA with Tukey's post-hoc analysis). There was no significant difference between control and burr groups (P>0.05). Results show that cement removal technique impacts on final cement-cement bonds. This in vitro study shows a significantly weaker bond when using OSCAR prior to re-cementation into an old cement mantle, compared to cement prepared with a burr or no treatment. These results have implications for surgical practice and decision-making about specific cement removal techniques used during cement-in-cement revision arthroplasty, suggesting that the risks and benefits of ultrasonic cement removal need careful consideration.