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Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_11 | Pages 228 - 228
1 Jul 2014
Schilcher J Sandberg O Isaksson H Aspenberg P
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Summary Statement

Atypical femoral fractures consist of a thin fracture line extending through the lateral cortex. The adjacent bone is undergoing resorption and mechanical abrasion and is often replaced with woven bone. The mechanical environment seems to inhibit healing.

Background

The pathophysiology behind bisphosphonate-associated atypical femoral fractures remains unclear. Histological findings at the fracture site itself might provide important clues. So far only one case describing the histological appearance of the fracture has been published.