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Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_19 | Pages 34 - 34
22 Nov 2024
Seixas J Altoé LS Santos AC Ribau A Abreu M Carvalho A Pereira F Soares D Sousa R
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Aim

Determine therapeutic and prognostic value of three different prosthetic joint infections (PJI) staging systems – JS-Bach, McPherson and PJI-TNM.

Method

Retrospective analysis of patients who received surgery for PJI between 2011 and 2022 at one single institution, including DAIR, 1-stage revision and 2-stage revision. We applied three staging systems - JS-Bach, McPherson, PJI-TNM – and categorize the results into A (less severe), B (intermediate) and C (most severe). Demographic data and comorbidities, anatomic location, type of treatment, recurrency of infection, final outcome and antibiogram were analyzed.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_22 | Pages 52 - 52
1 Dec 2017
Sousa A Gouveia P Coutinho L Rodrigues C Fonte H Cipriano A Santos AC Abreu M Amorim I Sousa R
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Aim

Autologous-labeled leukocytes combined with sulfur colloid bone marrow scan is the current imaging modality of choice for diagnosing prosthetic joint infection (PJI). Although this technique is reliable, in-vitro leukocyte labeling raises technical difficulties that limit its widespread use and sulfur colloid is increasingly difficult to obtain. Therefore, valid alternatives are needed. The purpose of our study was to determine the clinical value of 99mTc-sulesomab combined with 99mTc-colloidal rhenium sulphide (nanocolloid) bone marrow imaging in the diagnosis of infection in painful total joint arthroplasties.

Materials and methods

A retrospective study was conducted on a cohort of 53 patients with painful hip or knee prostheses that underwent 99mTc-sulesomab and 99mTc-nanocolloids sequentially, between January 2008 and December 2016. The combined images were interpreted as positive for infection when there was activity on the sulesomab scan without corresponding activity on the bone marrow scan. The final diagnosis was made with microbiological findings or by clinical follow up of at least 12 months.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 567 - 567
1 Sep 2012
Sousa R Santos AC Pereira A Massada M Oliveira A
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Background

Previous data from our institution show that more than half of all prosthetic joint infections are due to S. aureus. A significant proportion of these bacteria may have an endogenous source. Detecting and treating asymptomatic S. aureus nasal carriers preoperatively has been shown to reduce the risk of infection.

Material and Methods

This is an ongoing prospective study that started in March/2009 and involves primary total knee or hip arthroplasties candidates. So far preoperative nasal swab cultures were performed in 211(61%) out of 347 patients operated until April/2010. Carriers are identified and randomly chosen for preoperative treatment consisting of nasal mupirocin twice a day and daily cloro-hexidine baths in the 5 days that precede surgery. Antibiotic prophylaxis is cefazolin 24hours adding a single vancomycin dose in MRSA carriers.