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Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_1 | Pages 22 - 22
1 Feb 2021
Kamath A Acuna A Jella T Cwalina T Samuel L
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Introduction

Innovations in orthopaedic technology and infrastructure growth often require significant funding. Although an increasing trend has been observed for third-party investments into medical startups and physician practices, no study has examined the role of this funding in orthopaedics, including the influence of venture capital (VC). Therefore, this study analyzed trends in VC investments related to the field of orthopaedic surgery, as well as the characteristics of companies receiving said investments.

Methods

Venture capital investments into orthopaedic-related businesses were reviewed from 2000–2019 using Capital IQ, a proprietary market intelligence platform documenting financial transactions. The dataset was initially filtered to include healthcare-related venture capital transactions pertaining to the field of orthopaedic surgery. The final list of VC investments and their corresponding businesses were categorized by transaction year, amount (in USD), and orthopaedic subspecialty. The number and sum of VC investments was calculated both annually and cumulatively across the entire study period. Linear regression was used for trend analysis within two distinct, decade-long timeframes (2000–2009 and 2010–2019) and one-way analysis of variance was used to assess differences across orthopaedic subspecialties.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_1 | Pages 31 - 31
1 Feb 2021
Acuña A Jella T Barksdale E Samuel L Kamath A
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Introduction

Although multiple studies have consistently demonstrated that orthopaedic surgeons receive greater transfers of value than other specialties, the industry payments of providers involved in practice guideline formation have not been explored. Therefore, the purpose of our analysis was to evaluate the industry payments among authors of the Appropriate Use Criteria (AUC) from the American Academy of Orthopaedic Surgeons (AAOS).

Methods

The publicly available web portal (OrthoGuidelines.org) from the AAOS was queried for all AUCs released over the past decade for the management of musculoskeletal pathologies. For each AUC available through this portal, information related to the AUC and its respective voting members were recorded. We used this information to conduct a retrospective cross-sectional analysis of the CMS Open Payments Database. This information was utilized to determine the number of total value of industry payments to AUC voting committee members during the year of voting for AUC criteria. The total amount of industry payment to AUC voting members was calculated, per each AUC, annually, as well as per orthopaedic subspecialty. The average total industry payment per voting member was calculated for each AUC and compared with the average total industry payment per orthopaedic surgeon nationally, in the same year. All descriptive data analyses were performed in Microsoft Excel 2016 (MicrosoftCorp).


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 32 - 32
1 Feb 2020
Chughtai M Samuel L Kamath A
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The anterior approach for total hip arthroplasty (THA) has been associated with a faster earlier functional recovery and has gained increasing utilization for primary THA exposure. However, some studies have suggested a higher risk of femoral complications, as well as difficulty with femoral exposure. Techniques of soft tissue releases have been described to offer better femoral exposure, and to help mitigate complications like femoral fracture or breach of the canal with broaching. However, appropriate titrated soft release remains important to decrease potential risk of dislocation. Here we present a suggested technique and hierarchy of soft tissue releases to adequately expose the femur. In addition, we discuss adjunctive table and patient position maneuvers for femoral exposure, as well as more extensile and revision techniques if necessary.

For any figures or tables, please contact authors directly.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 35 - 35
1 Feb 2020
Chughtai M Samuel L Kamath A
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Introduction

The purpose of the study was to assess the clinical outcomes of an algorithm for soft tissue femoral release in anterior approach (AA) total hip arthroplasty (THA). Specifically, the following were assessed in this series of patients utilizing a standardized soft tissue release sequence: 1) clinical outcomes with the Harris Hip Score (HHS); 2) re-operation rates; 3) component survivorship; and 4) complications.

Methods

We retrospectively analyzed a prospectively maintained database of patients who underwent AA THA from 2014 to 2017. A total of 1000 patients were included, with minimum follow up of 2 years (range 2–5 years). The mean age was 65 years (range, 22–89), 48% were males, and the mean Body Mass Index was 34 (range, 20–52). Descriptive statistics were performed for most endpoints except for component survivorship, which was assessed with Kaplan-Meier analysis.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_1 | Pages 110 - 110
1 Feb 2020
Samuel L Warren J Rabin J Acuna A Shuster A Patterson J Mont M Brooks P
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Background

Proper positioning of the acetabular component is critical for prevention of dislocation and excessive wear for total hip arthroplasty (THA) and hip resurfacing. Consideration of preoperative pelvic tilt (PT) may aid in acetabular component placement. The purpose of this study was to investigate how PT changes after hip resurfacing, via pre and post-operative radiographic analysis of anterior pelvic plane (APP), and whether radiographic analysis of the APP is a reproducible method for evaluating PT in resurfaced hips.

Methods

A consecutive group of 228 patients from a single surgeon who had hip resurfacing were evaluated. We obtained x-rays from an institutional database for these patients who had their surgeries between January 1st, 2014 to December 31st, 2016. Pelvic tilt (PT) was measured by two observers before and after resurfacing utilizing a standardized radiographic technique. Correlation coefficients were calculated for PT measurements between observers, and pre- and post-surgery.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_1 | Pages 109 - 109
1 Feb 2020
Samuel L Rabin J Sultan A Arnold N Brooks P Mont M
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Introduction

Metal-on-Metal (MoM) bearing surfaces were historically used for young patients undergoing total hip arthroplasty, and remain commonplace in modern hip resurfacing. In theory, it has been postulated that metal ions released from such implants may cross the placental barrier and cause harm to the fetus. In light of this potential risk, recommendations against the use of MoM components in women of child-bearing age have been advocated. The purpose of this systematic review was to evaluate: 1) the Metal-on-Metal bearing types and ion levels found; 2) the concentrations of metals in maternal circulation and the umbilical cord; and 3) the presence of abnormalities in the fetus

Methods

A comprehensive literature review was conducted of studies published between January 1st, 1975 and April 1st, 2019 using specific keywords. (See Fig 1). We defined the inclusion criteria for qualifying studies for this review as follows: 1) studies that reported on the women who experienced pregnancy and who had a Metal-on-Metal hip implant; 2) studies that reported on maternal metal ions blood and umbilical cord levels; and 3) studies that reported on the occurrence of fetal complications. Data on cobalt and chromium ion levels in the maternal blood and umbilical cord blood, as well as the presence of adverse effects in the infant were collected. Age at parturition and time from MoM implant to parturition were also collected. A total of 6 studies were included in the final analysis that reported on a total of 21 females and 21 infants born. The mean age at parturition was 40 years (range, 24–41 years), and the mean time from MoM implantation to parturition was 47.2 months (range, 11–119 months).


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 36 - 36
1 Feb 2020
Samuel L Munim M Kamath A
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The Bernese periacetabular osteotomy (PAO) is a well-established procedure in the management of symptomatic hip dysplasia. The associated Smith-Petersen exposure offers excellent visualization of the acetabulum and control of acetabular osteotomy and mobilization. The traditional exposure of the true pelvis involves osteotomy of the iliac wing in order to mobilize the sartorial and inguinal ligament insertion. However, full osteotomy of the iliac spine may necessitate screw fixation if a relatively large segment of bone is included. A known complication with screw fixation of the iliac wing osteotomy involves failure of fixation and screw back out. Moreover, the screw may be irritative to the patient even in the setting of adequate fixation. A larger osteotomy may also injure the lateral femoral cutaneous nerve as it travels near the anterior superior spine. To minimize the risk of these potential complications, a wafer osteotomy may be used to develop a sleeve of tissue involving the sartorial insertion. Markings may be made so that the curvilinear incision is centered about the anterior-superior iliac spine (ASIS). The sartorial sleeve also mobilizes the entirety of the lateral femoral cutaneous nerve medially as it runs and branches to varying degrees in a fatty tissue layer in the tensor-sartorius interval directly beneath the subcutaneous layer, thereby affording protection throughout the procedure. When the ASIS is first osteotomized as a several millimeter-thick mobile fragment and reflected, the sartorius attachment to the mobile fragment of the wafer osteotomy may be preserved. Furthermore, the wafer osteotomy may be re-fixed to the stable pelvis during closure with simple heavy suture fixation alone, avoiding screw insertion or associated removal. Because only a wafer or bone is taken during the spine osteotomy, more bone is available at the ASIS for fixation of the mobile fragment after repositioning. In this technical note, we describe the wafer osteotomy technique in further detail.

For any figures or tables, please contact authors directly.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 28 - 28
1 Feb 2020
Arnold N Samuel L Karnuta J Munim M Sultan A Kamath A
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Background

Standard preoperative protocols in total joint arthroplasty utilize the International Normalized Ratio (INR) to determine patient coagulation profiles. However, the relevance of preoperative INR values in joint arthroplasty remains controversial. Acceptable INR cutoff values for joint replacement are inconsistent, and are often based on studies of primary arthroplasty, or even non-orthopedic procedures. This analysis examined the relationship between preoperative INR values and post-operative outcomes in revision total hip arthroplasty (rTHA). Optimal cutoff INR values correlated with specific outcomes were subsequently determined.

Methods

The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) was retrospectively queried for revision total hip arthroplasty procedures performed between 2006 and 2017. Patients with a preoperative INR collected no later than 1 day prior to surgery were further stratified for analysis. INR values which correlated with specific outcomes were determined using receiver operating characteristics (ROC) curves for each outcome of interest. The optimal cutoff INR value for each outcome was then obtained using univariate and multivariate models which determined INR values that maximized both sensitivity and specificity.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 37 - 37
1 Feb 2020
Acuña A Samuel L Sultan A Kamath A
Full Access

Introduction

Acetabular dysplasia, also known as developmental dysplasia of the hip, has been shown to contribute to the onset of osteoarthritis. Surgical correction involves repositioning the acetabulum in order to improve coverage of the femoral head. However, ideal placement of the acetabular fragment can often be difficult due to inadequate visualization. Therefore, there has been an increased need for pre-operative planning and navigation modalities for this procedure.

Methods

PubMed and EBSCO Host databases were queried using keywords (preoperative, pre-op, preop, before surgery, planning, plan, operation, surgery, surgical, acetabular dysplasia, developmental dysplasia of the hip, and Hip Dislocation, Congenital [Mesh]) from 1974 to March 2019. The search generated 411 results. We included all case-series, English, full-text manuscripts pertaining to pre-operative planning for congenital acetabular dysplasia. Exclusion criteria included: total hip arthroplasty (THA) planning, patient population mean age over 35, and double and single case studies.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 31 - 31
1 Feb 2020
Acuña A Samuel L Yao B Faour M Sultan A Kamath A Mont M
Full Access

Introduction

With an ongoing increase in total knee arthroplasty (TKA) procedural volume, there is an increased demand to improve surgical techniques to achieve ideal outcomes. Considerations of how to improve post-operative outcomes have included preservation of the infrapatellar fat pad (IPFP). Although this structure is commonly resected during TKA procedures, there is inconsistency in the literature and among surgeons regarding whether resection or preservation of the IPFP should be achieved. Additionally, information about how surgical handling of the IPFP influences outcomes is variable. Therefore, the purpose of this systematic review was to evaluate the influence of IPFP resection and preservation on post-operative flexion, pain, Insall-Salvati Ratio (ISR), Knee Society Score (KSS), patellar tendon length (PTL), and satisfaction in primary TKA.

Methods

A systematic literature search was performed to retrieve all reports that evaluated IPFP resection or preservation during total knee arthroplasty (TKA). The following databases were queried: PubMed, EBSCO host, and SCOPUS, resulting in 488 unique reports. Two reviewers independently reviewed the studies for eligibility based on pre-established inclusion and exclusion criteria. A total of 11 studies were identified for final analysis. Patient demographics, type of surgical intervention, follow-up duration, and clinical outcome measures were collected and further analyzed. This systematic review reported on 11,996 total cases. Complete resection was implemented in 3,723 cases (31%), partial resection in 5,458 cases (45.5%), and preservation of the IPFP occurred in 2,815 cases (23.5%). Clinical outcome measures included patellar tendon length (PTL) (5 studies), knee flexion (4 studies), pain (6 studies), Knee Society Score (KSS) (3 studies), Insall-Salvati Ratio (ISR) (3 studies), and patient satisfaction (1 study).