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Bone & Joint Research
Vol. 5, Issue 10 | Pages 453 - 460
1 Oct 2016
Ernstbrunner L Werthel J Hatta T Thoreson AR Resch H An K Moroder P

Objectives

The bony shoulder stability ratio (BSSR) allows for quantification of the bony stabilisers in vivo. We aimed to biomechanically validate the BSSR, determine whether joint incongruence affects the stability ratio (SR) of a shoulder model, and determine the correct parameters (glenoid concavity versus humeral head radius) for calculation of the BSSR in vivo.

Methods

Four polyethylene balls (radii: 19.1 mm to 38.1 mm) were used to mould four fitting sockets in four different depths (3.2 mm to 19.1mm). The SR was measured in biomechanical congruent and incongruent experimental series. The experimental SR of a congruent system was compared with the calculated SR based on the BSSR approach. Differences in SR between congruent and incongruent experimental conditions were quantified. Finally, the experimental SR was compared with either calculated SR based on the socket concavity or plastic ball radius.


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_11 | Pages 1 - 1
1 Oct 2015
Korntner S Kunkel N Lehner C Gehwolf R Wagner A Augat P Resch H Bauer H Traweger A Tempfer H
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Introduction

Metabolic disorders are among known risk factors for tendinopathies or spontaneous tendon ruptures. However, the underlying cellular and molecular mechanisms remain unclear. We have previously shown that human and rat tendon cells produce and secrete insulin upon glucose stimulation. Therefore, we hypothesize that nutritional glucose uptake affects tendon healing in a rat model.

Materials and Methods

Unilateral full-thickness Achilles tendon defects were created in 60 female rats. Animals were randomly assigned to three groups receiving different diets for 2 weeks (high glucose diet, low glucose/high fat diet, control diet). Gait analysis was performed at three time points (n=20/group). In addition, tendon thickness, biomechanical (n=14/group), and histological and immunohistochemical analysis was conducted. Subsequently, a subtractive-suppression-hybridization (SSH) screen comparing cDNA pools (n=5) prepared from repair tissues of the high glucose and the control diet group was conducted to identify differentially expressed genes.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 180 - 180
1 Sep 2012
Auffarth A Matis N Lederer S Karpik S Koller H Hitzl W Resch H
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Introduction

Depending on patient's age, risk factors and pretraumatic mobility, a total- or hemiarthroplasty of the hip have become the treatment of choice in femoral neck fractures(1–4). Internal fixation has shown to provide minor results. The majority of these patients are therefore treated by a hemiarthroplasty of the hip. Since the primary goal is to regain the pretraumatic level of mobility as soon as possible(3;5), we sought to investigate, if a minimal invasive anterior approach would be beneficial in regard of perioperative blood loss(6), postoperative pain(7;8) and thus postoperative mobility(9).

Patients and methods

In a randomised controlled trial, 48 patients were treated by a hemiarthroplasty of the hip via an anterior or lateral approach in supine position within 72 hours after trauma(10). Apart from parameters like age, ASA-Score or Body-mass-index, the main focus was set on perioperative blood loss, pain and postoperative mobilisation. All data collected were compared between groups to detect statistical significant differences. Additionally the same parameters were checked for significant differences comparing patients with or without complications within their group.