Radiotherapy is a well-known local treatment for spinal metastases. However, in the presence of postoperative systemic therapy, the efficacy of radiotherapy on local control (LC) and overall survival (OS) in patients with spinal metastases remains unknown. This study aimed to evaluate the clinical outcomes of post-surgical radiotherapy for spinal metastatic non-small-cell lung cancer (NSCLC) patients, and to identify factors correlated with LC and OS. A retrospective, single-centre review was conducted of patients with spinal metastases from NSCLC who underwent surgery followed by systemic therapy at our institution from January 2018 to September 2022. Kaplan-Meier analysis and log-rank tests were used to compare the LC and OS between groups. Associated factors for LC and OS were assessed using Cox proportional hazards regression analysis.Aims
Methods
The purpose of this investigation was to prospective compare the results of artificial femoral head replacement with those of treatment with a DHS internal fixation for unstable intertrochanteric fractures in elderly patients. Sixty-one cases of aged patients with intertrochanteric fractures were randomized into two treatment groups. All patients were followed for a minimum of four years from 9.1999 to 4.2003, 29 patients were treated with artificial femoral head replacement, the other were treated with DHS internal fixation. The clinical results of two ways for the treatment of aged patients with intertrochanteric fractures were observed. There were no significant differences between the groups in terms of functional outcomes, blood loss, or units of blood transfused. Patients treated with artificial femoral head replacement had a shorter hospital stay and operative time, less time to weight-bearing, fewer general complications, and lower mortality rate compared with those treated with the DHS internal fixation. We conclude that in elderly patients with an unstable intertrochanteric femoral fracture, a artificial femoral head replacement provides superior clinical outcomes but no advantage with regard to functional outcome when compared with a DHS internal fixation.
