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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_3 | Pages 100 - 100
23 Feb 2023
Tran T Driessen B Yap V Ng D Khorshid O Wall S Yates P Prosser G Wilkinson M Hazratwala K
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Clinical success of prostheses in joint arthroplasty is ultimately determined by survivorship and patient satisfaction. The purpose of this study was to compare (non-inferiority) a new morphometric designed stem for total hip arthroplasty (THA) against an established comparator.

A prospective randomised multi-centre study of 144 primary cementless THA performed by nine experienced orthopaedic surgeons was completed (70 received a fully coated collarless tapered stem and 74 received a morphometric designed proximally coated tapered stem). PROMs and blood serum markers were assessed preoperatively and at intervals up to 2-years postoperatively. In addition, measures of femoral stem fit, fill and subsidence at 2-years post-operatively were measured from radiographs by three observers, with an intra-class correlation coefficient of 0.918. A mixed effects model was employed to compare the two prosthesis over the study period. A p-value <0.05 was considered statistically significant.

Demographics, Dorr types and blood serum markers were similar between groups. Both stems demonstrated a significant improvement in PROMs between the pre- and post-operative measurements, with no difference at any timepoint (p > 0.05). The fully coated tapered collarless femoral stem had a non-significantly higher intra-operative femoral fracture rate (5.8% vs 1.4%, p = 0.24), with all patients treated with cable fixation and partial weight bearing. The mean subsidence at 2-years was 2.5mm +/- 2.3mm for the morphometric stem and 2.4mm +/- 1.8mm for the fully coated tapered collarless femoral stem (p = 0.879). There was one outlier in each group with increased subsidence (fully coated tapered collarless femoral stem 6.9mm, morphometric wedge stem 7.4mm), with both patients reporting thigh pain at 2 years.

When compared with an established stem, the newer designed morphometric wedge stem performed well with comparable radiological and PROM outcomes at 2 year follow up. Continued follow-up is required for long term benchmarking.


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_2 | Pages 36 - 36
10 Feb 2023
Driessen B Yap V Ng D Korshid O Wall S Yates P Prosser G Wilkinson M Hazratwala K Tran. T
Full Access

Clinical success of prostheses in joint arthroplasty is ultimately determined by survivorship and patient satisfaction. The purpose of this study was to compare (non-inferiority) a new morphometric designed stem for total hip arthroplasty (THA) against an established comparator.

A prospective randomised multi-centre study of 144 primary cementless THA performed by nine experienced orthopaedic surgeons was completed (70 received a fully coated collarless tapered stem and 70 received a morphometric designed proximally coated tapered stem). PROMs and blood serum markers were assessed preoperatively and at intervals up to 2-years postoperatively. In addition, measures of femoral stem fit, fill and subsidence at 2-years post-operatively were measured from radiographs by three observers, with an intra-class correlation coefficient of 0.918. A mixed effects model was employed to compare the two prostheses over the study period. A p-value <0.05 was considered statistically significant.

Demographics and Dorr types were similar between groups. Both stems demonstrated a significant improvement in PROMs between the pre- and post-operative measurements, with no difference at any timepoint (p > 0.05). The fully coated tapered collarless femoral stem had a non-significantly higher intra-operative femoral fracture rate (5.8% vs 1.4%, p = 0.24), with all patients treated with cable fixation and partial weight bearing. The mean subsidence at 2-years was 2.5mm +/- 2.3mm for the morphometric stem and 2.4mm +/- 1.8mm for the fully coated tapered collarless femoral stem (p = 0.879). There was one outlier in each group with increased subsidence (fully coated tapered collarless femoral stem 6.9mm, morphometric wedge stem 7.4mm), with both patients reporting thigh pain at 2 years.

When compared with an established stem, the newer designed morphometric wedge stem performed well with comparable radiological and PROM outcomes at 2 year follow up. Continued follow-up is required for long term benchmarking.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 369 - 369
1 Jul 2010
Prosser G Glithero P O’Hara J
Full Access

The purpose of the study was to assess the usefulness of this combination of operations in this challenging patient group.

18 patients (19 hips) with cerebral palsy and painful subluxed or dislocated hips underwent hip resurfacing with shortening and rotation osteotomy of the femur between 1999 and 2005. The mean age was 25 (range 14–59) and follow-up averaged 47 months. Eleven patients were quadriplegic, five were diplegic and two were hemiplegic.

There were no infections. There were two plate cut-outs and two dislocations. All stabilised following necessary treatment. Four plates were removed after about one year. All quadriplegic and four of the diplegic patients were chair-bound pre-operatively. Their carers all felt that their comfort sitting had improved. Seventeen patients (eighteen hips) were pain-free at latest follow-up. One patient, whose plate had not been removed had some lateral tenderness on transferring, but no apparent pain on sitting. Three of the previously chairbound diplegic patients were able to stand and one was able to walk.

As all eighteen of the carers were very satisfied with the outcome, this approach to the treatment of these challenging patients has proved promising


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 192 - 192
1 Mar 2010
D’Alessandro P Wood D Prosser G Carey-Smith R Nivbrant B Lloyd D
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Introduction: Treatment of dual compartment osteoarthritis remains controversial, with conjecture over whether Uni-Compartmental (‘UKA’) or Total Knee Arthroplasty (‘TKA’) is more appropriate for patients with patello-femoral disease. The ‘Journey Deuce’ 2/3 Knee Arthroplasty (‘2/3 Knee’) (Smith & Nephew) is a bi-cruciate retaining prosthesis designed to treat this subgroup of patients with both antero-medial and patello-femoral disease.

We have conducted a prospective, observational clinical trial of 34 patients with dual compartment osteoarthritis of the knee treated with a 2/3 Knee.

Aims: To assess the safety and clinical efficacy outcomes of the 2/3 Knee.

Method: All patients pre-op leg alignment films, as well as MRI or arthroscopy to confirm the inclusion criteria of dual compartment osteoarthritis with a preserved lateral compartment and intact cruciate ligaments. All operations were performed by a single surgeon (DW) using computer assisted surgery (CAS) and a minimally invasive technique (MIS) at a local university affiliated private hospital (HPH).

Exclusion criteria included obesity, inflammatory arthritis and a fixed flexion deformity > 10 degrees.

Subjective outcome measures included Oxford Knee Scores (OKS) and EQ-5D Scores. RSA beads were implanted at surgery to detect loosening, micro-motion and prosthesis wear. Gait analysis was conducted at 1 year post op in a subgroup of patients.

Results: Follow up ranged from 6 months to 2 years. There have been no early failures requiring complete revision. The first 23 knees (18 patients) did not have primary resurfacing of the patella. Some of these patients suffered palpable and audible patello-femoral crepitus, with a subgroup (17%, 4 knees-3 patients) having associated anterior knee pain. This subgroup had revision procedures to resurface their patellae with resolution of their symptoms. All subsequent patients have had primary patella resurfacing with no incidence of Significant crepitus or anterior knee pain.

The patients have recorded Significant improvement in their Oxford Knee Scores at 6 months (mean reduction all patients: 17.3, resurfaced 20).

Early RSA results have not detected Significant migration to indicate early loosening. Gait analysis has shown that patients return to approximate normal rather than pre-operative gait.

Conclusions: Although longer follow up is required the 2/3 Knee appears a safe and effective treatment option for patients with dual-compartment osteoarthritis; with rehabilitation, function and gait tending towards that seen in UKA rather than TKA.

It is essential that patients undergo primary patella resurfacing to prevent crepitus and associated anterior knee pain.

A study comparing clinical outcomes of 2/3 Knee vs TKA is underway at our institution.