Purpose

The failure rate of total ankle arthroplasty (TAA) in rheumatoid patients may be higher than in osteoarthritis patients due to the medications used to treat rheumatoid arthritis and the comorbidities associated with this disease. The purpose of this study was to prospectively look at the intermediate-term outcomes of TAA in patients with rheumatoid arthritis and to compare the results to a matched cohort of patients with ankle osteoarthritis undergoing TAA.

Purpose

Weight loss is often advised to our patients and considered to make a substantial difference in most musculoskeletal symptoms. Patients with end stage ankle arthrosis have severe pain, diminished health related quality of life, and limited physical function.

They frequently refer to increased weight as a simple indicator of decline in their quality loose weight. Patients assume that weight loss will follow after surgery secondary to increased activity with reduced pain and disability.

Purpose: The global utilization of total ankle arthroplasty (TAR) has been increasing over the past decade; however there are a limited number of published prospective studies assessing intermediate and long term outcomes. The purpose of this clinical series is to prospectively review the mid-term clinical and radiographic outcomes of the Scandinavian Total Ankle Replacement (STAR) performed at two Academic Canadian University Centres.

Method: Between 1998 and 2005, 113 STARs were implanted into 99 patients at two Canadian centres. Prospective clinical and radiographic follow-up was performed. Validated and non-validated outcome questionnaires consisting of the AAOS foot and ankle questionnaire (a composite questionnaire made up of unaltered versions of the SF-36), AOFAS Hindfoot score, Foot Function Index (FFI), Ankle Osteoarthritis Scale (AOS) were completed in one arm (63/113 implanted TARs). In the other arm, (50/114) the patients were followed retrospectively with the same measures. Both groups had prospective radiographic follow-up using measures described by Wood et al.

Results: The average follow-up for both groups was 46.3 ± 17.6 months (or 3.8 years). Of the 113 implanted STARs, 33 (29.2%) required a re-operation. Of those, 20 (17.7%) went on to be revised. Six patients had repeat revision operations for a total of 26 revision operations. Of the 26 revision operations 14 (54%) were polyethylene liner exchanges, and 12 (46%) were revision of the metallic components. The median time to revision was 39.5 months. Three prosthesis (2.6%) went on to have a deep infection of their STAR. All three were effectively managed without requiring explantation of the STAR. One patient had infection in their revision IM Nail. Of the 113 initially implanted prostheses, 101 (89.3%) of the original TARs remained implanted at the conclusion of the study. Sustained benefit, across questionnaires, from the STAR was observed to persist to final follow up. 115/116 (99%) ankles followed showed evidence of osteolysis at the last STAR follow-up. The osteolysis was found to occur more commonly around the talar component, but occurred, for the most part, in a recognizable pattern around both the talus and the tibia. No significant differences between the two centers in pre-operative or intra-operative data were identified.

Conclusion: The STAR, in the mid-term, shows acceptable survival and revision rates. There are, however, some concerning findings on radiographic follow-up. It appears, upon initial investigation, that initial component position may be a factor that predicts concerning radiographic changes. Further investigation is required to substantiate this.

Purpose: To describe the pre- and one-year post-operative preference-based, health related quality of life (health state values) among a cohort of subjects with end-stage ankle arthritis treated with total ankle arthroplasty or ankle arthrodesis. This short-term study is not intended to compare the efficacy of arthoplasty and arthrodesis.

Method: The Short-Form 36 (SF-36) was prospectively completed by subjects enrolled in the Canadian Orthopaedic Foot and Ankle Society Multicentered Ankle Arthritis Outcome Study between 2003 and 2005. Preference-based quality of life was assessed pre-operatively and at one-year post-procedure using health state values (HSVs) derived from the SF-36 transformation described by Brazier (SF-6D). The SF-6D scores are anchored at 1.0 (full health) and at 0 (death). Basic patient demographic and treatment information was also collected. The decision to perform arthroplasty or arthrodesis was made by the attending surgeon.

Results: Two hundred four of the 214 eligible subjects had complete preoperative SF-36 data to allow transformation to SF-6D values. One-year follow-up was available for 114 of the participants. The mean age at surgery of the included subjects was 58.9 +/− 13.3 years. Of the patients with one-year follow-up, 56% were male and 59% had received total ankle arthroplasty. These demographics did not differ from the original preoperative cohort. The mean SF-6D score among all subjects with end-stage ankle arthrosis was 0.66 (95% CI 0.65 – 0.68). At one-year, the mean HSVs of the total ankle arthroplasty and ankle arthrodesis groups were 0.73 (95% CI 0.71 – 0.76) and 0.73 (95% CI 0.70 – 0.75), respectively. The reported pre-operative scores describe health states below normative data for the US population (0.76 +/− 0.01 for females, ages 55–64).

Conclusion: These are the first available HSVs for a cohort of patients with end-stage ankle arthritis treated with total ankle arthroplasty or ankle arthrodesis. These data demonstrate an improvement in preference-based quality of life following ankle arthroplasty or arthrodesis. At one-year follow-up, patient reported HSVs approach age-matched US norms.

Purpose: To compare failure rates, and patient functional outcomes, using the Dynamic Hip Screw (DHS) and Medoff Sliding Plate (MSP) for unstable intertrochanteric hip fractures.

Method: One hundred and sixty three consecutive patients with unstable intertrochanteric hip fractures, from three hospitals, were prospectively randomized to DHS or MSP. Inclusion and exclusion criteria were designed to focus on isolated unstable intertrochanteric hip fractures in ambulatory patients over age 60, without previous hip fractures or significant subtrochanteric extension. Patients were stratified by mental status and treating hospital. Randomization was performed intra operatively, after placement of a 135 degree guide wire. Follow up assessments were performed at regular intervals for a minimum of six months. The primary outcome was re-operation rate. The secondary outcome was patient function, using a validated outcome measure, the Hip Fracture Functional Recovery Score. Tertiary outcomes included: mortality, hospital stay, quality of reduction and mal union rate.

Results: 86 patients were randomized to DHS and 76 to MSP. The groups had similar patient demographics and pre fracture status (medical and functional). The patients had similar hospital course except there were more transfusions in the MSP group (2 vs. 1 unit). The quality of reduction was the same for each group but the operative time was longer in the MSP group (61 vs. 50 min). The rate of re-operation was low (3/86 in DHS and 2/76 in MSP) with no statistically significant difference. The indication for re-operation differed for the two groups as all three failures in the DHS group were related to screw cut out and both failures in the MSP arm were because of non union. The functional outcomes were the same for both groups with functional recovery scores at six months of 51% in the DHS arm and 49% in the MSP arm.

Conclusion: The two techniques produced similar results for the clinically important outcomes of the need for further surgery and functional status of the patients. For this challenging sub group of hip fractures, based on the equivalent results in this study either implant is a reasonable choice.

Summary: The SF-36, FFI, AOS and the AOFAS AHS were recorded pre and post-operatively in patients with end-stage ankle arthritis. Comparison of responsiveness shows the AOFAS score to be completely unresponsive.

Introduction: Outcome studies should include both general health and disease specific measures. The Short Form 36 (SF36) is validated and widely used in musculoskeletal disease. A number of disease specific scores are available for the foot and ankle but, at present there is no widely agreed and validated score used specifically in end-stage ankle arthritis (EAA).

Methods: 555 sets of pre and post-operative data on 239 EAA patients undergoing definitive treatment have been collected. The SF36 and three widely used Foot and Ankle scores (Foot Function Index (FFI), AOFAS Ankle Hindfoot Score (AHS) and Ankle Osteoarthritis Scale (AOS)) were recorded. We assessed the responsiveness (Standardized Response Mean (SRM) and Effect Size (ES)) and correlation (Spearman Rank Correlation) of each of the above scores.

Results: The SF36, FFI and AOS responded to change and correlated in sub-scale and total scores. The AHS did not respond to change in pain or total scores and did not correlate with any other score.

Using the three responsive scores there was a significant improvement in outcome with operative intervention (p< 0.0001) with each score. Using the SRM and the ES, the AOS showed the highest level of responsiveness. It also showed an increased response rate suggesting that patients find it more useable.

Conclusion: In future studies we would recommend the use of the SF36 and the AOS for assessment of patients with EAA. We would also discourage use of the AOFAS Ankle Hindfoot Score which we have demonstrated to be unresponsive to change.