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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVII | Pages 37 - 37
1 Jun 2012
Tang N Hung V Yeung H Liao C Lam T Lee K Ng B Cheng J
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Introduction

Genetic predisposition is a key causal factor in adolescent idiopathic scoliosis (AIS), which is the most common form of spinal deformity. However, common quantitative genetic effect estimates such as hereditability have not been fully evaluated and reported for this disorder. We aimed to determine the sibling recurrent risk and hereditability of AIS in first-degree relatives of 513 Chinese patients with this disorder.

Methods

Family members of 513 Chinese patients with AIS attending a scoliosis clinic were assessed. A diagnosis of AIS was made with the criteria of Cobb angle greater than 20°. The evaluation included clinical assessment and physical examination in a health screening centre by medical doctors with use of forward bending test. Any positive screening cases were referred to a scoliosis clinic for follow-up spinal radiograph. All radiographs were assessed by an orthopaedic surgeon in the scoliosis clinic. A population prevalence of scoliosis was obtained from the data of a territory-wide screening campaign. The prevalence of AIS among siblings of probands was measured both overall and divided by sex of siblings. The sibling recurrent risk (λs) was calculated for male and female siblings separately with reported population incidence of AIS.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVII | Pages 53 - 53
1 Jun 2012
Lam T Hung V Yeung H Yu F Chan C Ng B Lee K Qin L Cheng J
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Introduction

Adolescent idiopathic scoliosis (AIS) is associated with low bone mineral density, which could be related to its etiopathogenesis. Apart from bone density, bone micro-architectures are equally important for better understanding of disease initiation and progression in AIS. Quantitative assessment of bone quality is hampered by the invasive nature of investigations, until recently when the high-resolution pQCT (XtremeCT) became available for revolutionary in-vivo microimaging and derivation of bone micro-architectural parameters. Our objective was to use this powerful instrument to study bone qualities in AIS and compare findings with those from healthy controls.

Methods

48 girls with AIS and 84 sex-matched healthy controls were recruited. Cobb angle was measured with standing radiographs, and imaging of the non-dominant distal radius was captured with XtremeCT according to a standard protocol.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVII | Pages 54 - 54
1 Jun 2012
Lam T Hung VY Yeung H Chu W Ng B Lee K Qin L Cheng J
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Introduction

The main challenge in management of adolescent idiopathic scoliosis (AIS) is to predict which curve will progress so that appropriate treatment can be given. We previously reported that low bone mineral density (BMD) was one of the adverse prognostic factors for AIS. With advancement in imaging technology, quantitative ultrasound (QUS) becomes a useful method to assess bone density and bone quality. The objective of this study was to assess the role of QUS as a radiation-free method to predict curve progression in AIS.

Methods

294 girls with AIS were recruited at ages 11–16 years and followed up until skeletal maturity. 269 age-matched healthy girls were recruited as controls. They provided the normal reference for calculation of Z score for QUS parameters. QUS measurements, including BUA (broadband ultrasound attenuation), VOS (velocity of sound) and SI (stiffness index) of the calcaneum, BMD of femoral neck, menarche history, ages, and Cobb angle of the major curve were recorded at baseline as independent variables. The predictive outcome was curve progression defined as an increase of Cobb angle of 6° or more. Logistic regression model and the ROC curve were used for statistical analysis.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 255 - 255
1 May 2006
Mohil R Shah N Hopgood P Ng B Shepard G Ryan W Banks A
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Aim: To review results and complications of revision knee replacements.

Materials and Methods: We retrospectively reviewed 41 cases of cemented revision knee arthroplasty in 39 patients (15 male, 24 female) performed between 1993 and 2003. Data regarding clinical and functional outcomes and complications was recorded.

Results: Mean age at index (revision) operation was 67.8 years (32 to 86) and mean follow-up was 6.8 years (1.5 to 12). Average time to revision was 80 months (9 months to 23 years).

The indication for revision was aseptic loosening in 16 cases, and deep sepsis in 13 cases, (12 were done in 2 stages). Others included polyethylene wear in 4 knees, instability in 2, and 1 each of peri-prosthetic fracture, implant breakage and pain of undetermined origin. 3 revisions were performed for failed Link Lubinus patello-femoral replacement. Mean interval between staged procedures for sepsis was 2 months.

Reconstruction was performed using the Kinemax Revision system with the use of augments and stems. The modular rotating hinge was used in 4 cases. Surgical exposure included additional lateral release in 7 cases, tibial tubercle osteotomy in 4 and quadriceps snip in one.

Complications: Included 1 post-operative death due to haematemesis and 2 non-fatal cardiac complications. 1 patient was re-revised for aseptic loosening at 3.5 years, 1 needed an above knee amputation for intractable sepsis after multiple failed reconstructions and 1 is awaiting patellar revision.

At latest review, 7 patients had died due to unrelated causes with a pain free functioning knee prosthesis. Of the remaining 31, 26 patients had none or minimal pain. 21 were independently mobile with a satisfactory range of motion.10 patients needed a walking stick.

Conclusion: Revision total knee replacement can give satisfactory results in the short to medium term, although the complication rate can be significant. The procedure should be performed in specialist units. Revision in 2 stages for sepsis resulted in satisfactory control of infection in our study.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 22 - 22
1 Mar 2006
Ng B Soong V Sankar B Siddique I Maguire M Mohil R Henderson A
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Purpose: To evaluate the objective outcomes in patients who had undergone hardware removal after ORIF of calcaneus fractures.

Materials and Methods: Between 1994 and 2002, 31 cases of hardware removal was performed in 30 patients (25 male, 5 female) with an average age at operation of 47 years (31 to 65 years) were reviewed. Patients’ demographic details were recorded including smoking habit. Fracture patterns were graded according to the Sanders’ classification with preoperative CT scans. The clinical result was assessed using Bristol hind foot scoring system. Serial radiographs assessments were also recorded.

Results: Average follow-up was 4.5 years. Average delay from time of injury to surgery was 12.4 days (range 5 to 24 days). 7 (23%)fractures were Sanders’ type 2A, 8 (26%)fractures were type 2B, 6 (19%)fractures were type 2C, 2 (6%) fractures were type 3AB and 8 (26%) fractures were type 3AC. Average time from surgery to hardware removal was 27 months (range 11 to 45 months). There were 16 smokers and 14 non-smokers. There were 5 deep infections and 3 superficial wound infections after ORIF of calcaneus fractures. 84% of the patients shown objective improvement following hardware removal at the latest follow-up. 2 patients had unsuccessful hardware removal due to dense scarring. No wound infections were recorded. Smoking habit had no significant bearing on the objective outcome improvement following hardware removal (p= 0.891), time from surgery to hardware removal (p=0.53) and wound morbidity (p= 0.4882). Objective improvement showed a statistically significant improvement in the Sanders’ type 2 compared with Sanders’ type 3 (p=0.015).

Conclusion: Removal of hardware is justified in symptomatic patients following ORIF calcaneus fractures. It results in an improved objective outcome and has a low complication rate. Hardware removal may be considered in cases of Sanders’ type 2 calcaneus fractures which are refractory to improvement.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 288 - 288
1 Sep 2005
Sankar B Ng B Fehily M Henderson A
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Introduction: Stainsby’s procedure for correction of severe claw toe deformity is a relatively new procedure in foot and ankle surgery. The purpose of this study is to evaluate our early experience in a single institution.

Method: Between 1998 and 2002 we reviewed retrospectively 17 patients who had severe claw toe deformity who had undergone Stainsby’s procedure. All patients had lesser toe involvement. The records and radiographs were reviewed and the subjective assessment by telephone interview.

Results: Eleven females and six males were included. There were 21 feet and 42 toes with four bilateral feet involvement. Mean age of 56.7 years (range 40–78) and median follow-up was 28 months (range 8–48). Ten feet in nine patients undergone single lesser toe correction and 11 feet in eight patients undergone multiple toe correction were reviewed. Five patients (29.4%) with six feet suffered rheumatoid arthritis (RA); four patients (23.5%) with six feet suffered cavus deformity and the remaining eight patients (47.1%) with nine feet had isolated toe pathology. All patients were presented with shoe wear problem with 16 (94.1%) patients had pain related to callosities. Sixteen (94.1%) patients were satisfied with the results; two patients had persistent metatarsalgia. Forty (95.2%) toes had good alignment and two (4.8%) toes had recurrent asymptomatic clawing. Fifteen (88.2%) patients had unlimited daily activities. Eleven (64.7%) patients are able to have normal foot wear, four (23.5%) require insole support and two (11.8%) required soft padding only. Complications included sensory alteration in two patients who had multiple lesser toe correction and seven patients had superficial wound infection. There was no statistical difference in results related to number of toes operated on and association with RA.

Conclusion: Stainsby’s procedure remains a versatile surgical technique when dealing with severe claw toe deformity. It gives very good correction with high patients’ satisfaction rate and a low complication rate. We recommend this surgical technique, as one of the armamentarium foot and ankle surgeons should acquire.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 266 - 266
1 Mar 2004
Jena D Ng B Muddu B Richardson J
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Aims: This study aims to identify whether there is seasonal variation in proximal femoral fractures in ageing population. Methods: We carried out a study to find out whether there is a definite variation in the incidence of these fractures. The number of operated proximal femoral fractures across 31 hospitals of Northwest England and Scotland were collected on a monthly basis from 1994 to 1999. This database of 27,000 operated proximal femoral fractures was assessed statistically. Results: Our analysis reveals that the incidence of these fractures during December is about 17% higher than rest of the annual mean with a 2% standard error of the mean (SEM) and in January this increase is about 22% with a SEM of 1%. These trend and pattern were observed for both intra and extra capsular fractures of neck of femur and was consistent over the five years. There was no other significant change in the incidence pattern during other months of the year. Conclusions: This study, one of the largest of its kind ever carried out, proves that there is an increase in the incidence of hip fractures in the months of December and January. There should be appropriate allocation of manpower and rehabilitation facilities during the months of December and January to tackle this seasonal variation.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 238 - 238
1 Mar 2004
Ng B Misra A Hales P
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Aims: To evaluate the role of Blatt’s capsulodesis and scapholunate ligament repair in patients with chronic scapholunate instability. Methods: Nineteen (15 males, 4 females) patients with chronic scapholunate instability underwent surgical repair and dorsal capsulodesis. At a mean follow-up of 28 months, all patients were assessed to identify any improvement in analogue pain scores, grip strength, range of movement of wrist and overall result of surgery. Results: Pre-operative arthroscopic findings revealed a scapholunate gap of > 2mm and ease at visualising the capitate by passing the scope through the scapholunate interval confirming the diagnosis. Surgery consisted of repair of torn ligament and supplementary dorsal capsulodesis (Blatt’s technique). 12 patients (63%) had returned to normal working activities at pre-injury level. There was a marked improvement in level of pain (mean pain level= 8.7 pre-operative vs. 2.3 postoperative, p=0.003). Seventeen patients (89.5%) would recommend this operation to others with similar problems. Only one patient (5%) rated the results as worse off following surgical intervention. Statistically significant pain improvement and grip strength were noted. ROM of wrist did not improve in most patients. Conclusion: Treatment of the chronic scapholunate instability remains contentious. It is suggested early surgical intervention will benefit majority of the patients. Our result concluded that Blatt’s capsulodesis has a role in chronic scapholunate instability.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 336 - 336
1 Mar 2004
Giannoudis P Ng B De Costa A Smith R
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Aims: To identify the incidence of neurological deþcit and functional outcome following displaced acetabular fractures. Methods: We carried out a prospective study of 136 patients who underwent skeletal stabilization of displaced acetabular fractures. Patients with sciatic nerve injuries were identiþed, assessed and followed up clinically. Routine EMG and nerve conduction studies were performed post-operatively on all cases with clinical proven neurological lesions to correlate the level, severity of the lesion and monitor progress of recovery. Results: 27 patients (19.8%) have neurological deþcit identiþed preoperatively. In 12 patients where the femoral heads were dislocated posteriorly. 20 were male and 7 were female. The mean age was 33.8 years (range 16–66). 15 patients had associated injuries but none of the patients had injury to the spinal cord. The mean ISS was 12.6 (range 9–34). The mean follow up was 3.4 years (range 1.5–6 years). 13 patients with complete drop foot at presentation. 9 patients had EMG proven double crush lesion. 3 patients had ipsilateral knee injury. 2 patients had intraopearative iatrogenic injury. All 9 patients with double crush syndrome have no improvement in function. Conclusions: Acetabular fractures associated with sciatic nerve injuries are devastating injuries with signiþcant long term morbidity. 50% patients showed improvement with time. Identiþcation of double crush lesion is vital as it is associated with poorer functional recovery as compared to single lesion.