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Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_13 | Pages 16 - 16
1 Nov 2021
Frydendal T Christensen R Mechlenburg I Mikkelsen LR Overgaard S Ingwersen KG
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Introduction and Objective

Hip osteoarthritis (OA) is the leading cause for total hip arthroplasty (THA). Although, being considered as the surgery of the century up to 23% of the patients report long-term pain and deficits in physical function and muscle strength may persist after THA. Progressive resistance training (PRT) appear to improve several outcomes moderately in patients with hip OA. Current treatment selection is based on low-level evidence as no randomised controlled trials have compared THA to non-surgical treatment. The primary objective of this trial is to determine the effectiveness of THA followed by standard care compared to 12 weeks of supervised PRT followed by 12 weeks of optional unsupervised PRT, on changes in hip pain and function, in patients with severe hip OA after 6 months.

Materials and Methods

This is a protocol for a multicentre, parallel-group, assessor blinded, randomised controlled superiority trial. Patients aged ≥50 years with clinical and radiographic hip OA found eligible for THA by an orthopaedic surgeon will be randomised to THA or PRT (allocation 1:1). The primary outcome will be change in patient-reported hip pain and function, measured using the Oxford Hip Score. Key secondary outcomes will be change in the Hip disability and Osteoarthritis Outcome Score subscales, University of California Los Angeles Activity Score, 40-meter fast-paced walk test, 30-second chair stand test, and number of serious adverse events.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_13 | Pages 34 - 34
1 Nov 2021
Larsen JB Østergaard HK Thillemann TM Falstie-Jensen T Reimer L Noe S Jensen SL Mechlenburg I
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Introduction and Objective

Only few studies have investigated the outcome of exercises in patients with glenohumeral osteoarthritis (OA) or rotator cuff tear arthropathy (CTA), and furthermore often excluded patients with a severe degree of OA. Several studies including a Cochrane review have suggested the need for trials comparing shoulder arthroplasty to non-surgical treatments. Before initiation of such a trial, the feasibility of progressive shoulder exercises (PSE) in patients, who are eligible for shoulder arthroplasty should be investigated. The aim was to investigate whether 12 weeks of PSE is feasible in patients with OA or CTA eligible for shoulder arthroplasty. Moreover, to report changes in shoulder function and range of motion (ROM) following the exercise program.

Materials and Methods

Eighteen patients (11 women, 14 OA), mean age 70 years (range 57–80), performed 12 weeks of PSE with 1 weekly physiotherapist-supervised and 2 weekly home-based sessions. Feasibility was measured by drop-out rate, adverse events, pain and adherence to PSE. Patients completed Western Ontario Osteoarthritis of the Shoulder (WOOS) score and Disabilities of the Arm, Shoulder and Hand (DASH).


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_4 | Pages 97 - 97
1 Mar 2021
Reimer L Jacobsen JS Mechlenburg I
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Greater trochanteric pain syndrome (GTPS) is a common and disabling hip condition. Hypermobility has been suggested as a possible cause of GTPS. The purpose of this study was to report the prevalence of hypermobility and to investigate its impact on hip-related function and awareness in patients with GTPS. This cross-sectional study was based on a cohort of patients diagnosed with GTPS in the 2013–2015 period. Hypermobility was investigated with the Beighton Score and defined by a cut-off score ≥5. Data on patients' current hip function and awareness were collected with the questionnaires the Copenhagen Hip and Groin Outcome Score and the Forgotten Joint Score. A total of 612 patients with GTPS were identified based on the diagnosis system; out of those, 390 patients were assessed for eligibility, and 145 (37%) were included. The prevalence of hypermobility within this cohort was estimated to be 11% (95% confidence interval (CI): 3–26%) for males and 25% (95% CI: 17–34%) for females. No significant association was found between hypermobility and self- reported hip function and awareness. We recommend that future studies of GTPS will include hypermobility and investigate the consequences of hypermobility among patients with GTPS.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_4 | Pages 62 - 62
1 Apr 2018
Mechlenburg I Mortensen L Schultz J Elsner A Jacobsen JS Jakobsen SS Soballe K Dalgas U
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Introduction

Progressive resistance training (PRT) as a mean to reduce symptoms in patients with hip dysplasia (HD) has not yet been tried out. The aim of this study was to examine if PRT is feasible in patients with HD. A secondary purpose was to report data on changes of patient reported outcomes, muscle performance and hip muscle strength following PRT.

Materials and methods

Patients diagnosed with HD on the waiting list for a periacetabular osteotomy (PAO) were offered to participate in a PRT feasibility study. The PRT intervention consisted of 8-weeks of supervised PRT consisting of 20 training sessions with exercises for the hips and knees. Feasibility was evaluated as adherence, the number of dropouts and adverse events. Furthermore, pain was reported after each exercise and one day after a training session using a 100mm visual analog scale (VAS). Pain was categorized as “safe” (VAS ≤20), “acceptable” (VAS >20–50) and “high risk” (VAS >50). Pre- and post the intervention patients completed the Copenhagen Hip and Groin Outcome Score (HAGOS), performed two hop-tests on each leg and had their peak torque of the hip extensors and flexors assessed by isokinetic dynamometry.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_4 | Pages 63 - 63
1 Apr 2018
Daugaard R Tjur M Sliepen M Rosenbaum D Grimm B Mechlenburg I
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Introduction

Knee osteoarthritis (KOA) causes impairment through pain, stiffness and malalignment and knee joint replacement (KJR) may be necessary to alleviate such symptoms. There is disagreement whether patients with KJR increases their level of physical activity after surgery. The aim of this study is to investigate whether patients with KJR have a higher level of physical activity than patients with KOA, as measured by accelerometer-based method. Furthermore, to investigate whether patients achieve the same level of activity as healthy subjects five years post TJR.

Material and method

54 patients with KOA (29 women, mean age 62±8.6, mean BMI 27±5), 53 patients who had KJR five years earlier (26 women, mean age 66±7.2, mean BMI 30±5) and 171 healthy subjects (76 women, mean age 64±9.7, mean BMI 26±5) were included in this cross sectional study. The level of physical activity was measured over a mean of 5.5 days with a tri-axial accelerometer mounted on the thigh. Number of daily short walking bouts of


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_4 | Pages 64 - 64
1 Apr 2018
Jacobsen JS Hölmich P Thorborg K Bolvig L Jakobsen SS Søballe K Mechlenburg I
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Introduction

Intra-articular injury has been described as primary cause of pain in hip dysplasia. At this point it is unknown whether external muscle-tendon related pain coexists with intra-articular pathology.

The primary aim was to identify muscle-tendon related pain in 100 dysplasia patients. The secondary aim was to test if muscle-tendon related pain is linearly associated to self-reported hip disability and muscle strength in patient with hip dysplasia.

Materials and methods

One hundred patients (17 men) with a mean age of 29 years (SD 9) were included. Clinical entity approach was carried out to identify muscle-tendon related pain. Muscle strength was assessed with a handheld dynamometer and self-reported hip disability was recorded with the Copenhagen Hip and Groin Outcome Score (HAGOS).


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_11 | Pages 140 - 140
1 Jul 2014
Hjorth M Søballe K Jakobsen S Lorenzen N Mechlenburg I Stilling M
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Summary

Five year migration results of 49 large-head metal-metal (MoM) total hip arthroplasties show good implant stability and no association between implant migration and metal-ions levels, stem and cup position, or femoral bone mineral density.

Introduction

The failure mechanism of metal-metal (MoM) total hip arthroplasty has been related to metal wear-debris and pseudotumor, but it is unknown whether implant fixation is affected by metal wear-debris.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 337 - 337
1 Sep 2012
Liljensoe A Laursen JO Mechlenburg I
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Purpose

The purpose of this study were to investigate whether there is an association between the preoperative body mass index in total knee replacement patients and the effect three to five years postoperative.

Method

197 patients who had undergone primary total knee replacement in the period 1.1.2005–31.12.2006 participated in a three-five years of follow-up study. Outcome measures were self-rated health (SF-36), which consists of eight strands and two component scores, physical component score and mental component scores and the Knee Society rating system (KSS) (knee score and function scores), and improvement of the two KSS scores from baseline to follow-up.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 29 - 29
1 Mar 2009
Mechlenburg I Kold S Romer L Soballe K
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Background and purpose. At the Ganz periacetabular osteotomy the osteotomized acetabular fragment is reoriented in an adducted, extended and rotated position. Two screws fixate the acetabular fragment and the patients are allowed 30 kg weight bearing immediately after surgery. We were interested in examining the stability of the reoriented acetabulum after the Ganz osteotomy and accordingly the migration of the acetabular fragment was assessed by radiostereometry.

Methods. Thirty two dysplastic patients (thirty two hips), twenty seven females and five males were included in the study. Median age was 39 (20–57) years. Radio-stereometric examinations were done at one week, four weeks, 8 weeks and six months. Data are presented as mean with 95% CI.

Results. Six months postoperatively, the acetabular fragment had migrated 0.7mm (0.4–1.0mm) medially, and 0.7mm (0.5–0.9 mm) cranially. Mean rotation in valgus direction was 0.5° (−0.1–1.0°). In other directions, migration was below 0.4. There was no statistical difference between migration 8 weeks and 24 weeks postoperative in translation or rotation.

Interpretation. This is the first paper dealing with radio-stereometric analysis in Ganz osteotomy. Due to the very limited migration, we find our postoperative partial weight-bearing regime safe.