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Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 131 - 131
1 Mar 2010
Suzuki M Lee T Miyagi J Kobayashi T Sasho T Nakagawa K Fujiwara K Nishimura N Kuramoto K Uetsuki K Moriya H Takahashi K
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The aim of this study was to report a 3 year follow up of vitamin E add polyethylene in total knee arthroplasty. UHMWPE powder (GUR1050) was mixed with 0.3% of vitamin E before consolidation by direct compression molding. The vitamin E added UHMWPE was applied to the articular surface and patella in 65 patients (mean age, 69.6 years). Joint fluid concentrations of tocopherol and matrix metalloproteinase 9 were measured in vitamin E added UHMWPE cases one year after surgery, and were compared to those of conventional UHMWPE cases and osteoarthritis patients. Concentrations of α-tocopherol and γ-tocopherol were measured by using HPLC with ultraviolet-visible wavelength detection. Concentrations of matrix metalloproteinase 9 were detected by using enzyme immunoassay.

The Average Knee Society score were 91.7(clinical) and 76.7(functional). There were three failures (1 supracondylar fracture, and 2 skin necrosis). The average concentrations of α-tocopherol were 281.8μg/dL (10 cases) in the vitamin E group, 371.8μg/dL (15 cases) in the conventional group, and 317.8μg/dL (46 cases) in the osteoarthritis group. There were no significant differences among three groups. The average concentrations of γ-tocopherol were 43.4μg/dL in the vitamin E group, 52.3μg/dL in the conventional group, and 49.8μg/dL in the osteoarthritis group. There were no significant differences among three groups. The average concentrations of matrix metalloproteinase 9 were 83.2 ng/mL in the vitamin E group, 78.4 ng/mL in the conventional group, and 17.4 ng/mL in the osteoarthritis group. There was no significant difference between the vitamin E group and the conventional group. However, The matrix metalloproteinase 9 concentrations of the osteoarthritis group were significantly lower than others.

No cases exhibited measurable polyethylene wear or osteolysis and also no abnormal values relating to vitamin E on joint fluid examinations. At three year follow-up, vitamin E added polyethylene demonstrated the safe use for the human body.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 171 - 171
1 Mar 2008
Kishida S Harada Y Shirai C Miura Y Miyasaka T Yanagawa N Moriya H
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We usually plan surgery for total hip arthroplasty (THA)using pre-operative X-ray templates. However, the technique provides only two dimensional (2D) images and therefore has limitations for planning three-dimensional (3D) objects. Recently it has become possible to describe 3D images using computer programs that use free down loaded computer software (Hip-op) that enable comparison between 3D templates obtained by computed tomography (CT) and 2D conventional X-ray templates.

Six hip joints in 6 patients (1 male, 5 females; age range at the time of operation, 49–77 years) were evaluated. Five of the patients suffered from secondary osteoarthritis of the hip (secondary OA), while the remaining patient suffered from osteonecrosis of the femoral head (ONFH). All the patients underwent THA using a cement less femoral stem (ANCA-FIT Wright Medical Technology, Arlington, Tennessee, USA). Pre-operative planning was performed using Hip-op software (Rizzoli Institute, Bologna, Italy). After the THA surgery, we carried out a repeat CT scan that was used to analyze stem fitting in the femur.

In all the patients it proved easy to obtain the pre-operative template. In 4 patients, the correct stem size was selected pre-operatively, while in the other 2 patients, the planned stem size was one size smaller than that actually implanted. In the 4 patients in whom the correct stem was selected, 2 had their template correctly assessed by conventional 2D images, 1 patient’s template was one size smaller than the implant, while the remaining patient’s template was two sizes smaller than the implant. In the 2 patients who received implants one size smaller than the CT template, 1 patient had the stem inserted in the virus position while in the other patient a fracture occurred during implantation

Preoperative planning for THA using a CT-based computer templating system proved to be a useful technique for the orthopedic surgeons.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 169 - 169
1 Mar 2008
Miyagi J Suzuki M Funabashi N Tsuneizumi T Tsukeoka T Yanagawa N Moriya H
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Combined multi-detector row CT (MD-CT) pulmonary angiography (CTPA) and lower extremity venography (CTV) is an effective method for detection of pulmonary embolism (PE) and deep vein thrombosis (DVT). However, the usefulness of this method after total knee arthroplasty (TKA) has not been reported. The aim of this study is to evaluate our screening program in the management of thromboembolism.

Over a 1.5-year period, 30 patients with primary TKA were examined using an MD-CT (Lightspeed ultra 16.GE) before and 7th day after operation. 25 seconds after intravenous administration of 320ml of contrast material, CTPA was performed with 1.25-mm collimation and CTV from the iliac crest to the ankles was done with 0.625-mm collimation 165 seconds after contrastmaterial injection. The mean age of the patients was 72.2 (53–80). Twenty patients had osteoarthritis, nine had rheumatoid arthritis and one osteonecrosis. All patients were received 4 weeks of warfarin therapy and prophylaxis.

PE was observed in A1+2, A3, A6, A9, A10 area. PE was most frequently detected in A10 area of pulmonary artery (6/30). While, DVT was detected in only popliteal vein (6/30). The incidence of PE was 30% (9/30)and DVT 20% (6/30). Both PE and DVT were observed in 3 patients, the incidence was 10% (3/30).

Combined CTPA and CTV is a safe and accurate diagnotic method for detecting PE and DVT after TKA, and the ability to directly visualize emboli of this system is effective as therapeutic tool.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 32 - 32
1 Jan 2003
Moriya H Sasho T Wada Y
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The application of arthroscopic procedure for osteoarthritic knee is limited to rather initial stages of the disease. Here we report the results of new arthroscopic procedure, which was named arthroscopic posteromedial release, applied to relatively severe cases of medial type osteoarthrits (OA)

Forty-eight knees of 46 patients of OA knees with flexion contracture were treated with arthroscopic posteromedial release. Thirty-two were female and 14 were male. All the patients had been treated conservatively beforehand. The mean age of the patients was 71.6 (range, 47 to 84 years), the average range of motion was 13 to 129 degrees. Only one case was classified stage II in Kellgren Lowrence x-ray classification, 13 and 34 cases were stage III and IV respectively. The average femoro-tibial angle was 183.4+-4.4 degrees.

In surgery, we release the joint capsule along with the medial tibial condyle, arthroscopic debridement including medial meniscentomy was performed at the same time. If some cases, medial collateral ligament was cut transversely to obtain enough joint space. We use hyaluronan intra-articularly once a week for 5 weeks postoperatively. Patients were examined at 3,6,12,18 and 24 months after surgery and evaluated subjectively and objectively with the rating system of Japanese Orthopaedic Association knee score (JOA score). Clinical results were also classified excelletn, good, fair and poor by our criteria.

Eighty-three per cent (40 knees) of patients were satisfied at their last follow up. Sixty-seven percent (32 knees) of the patients were excellent or good. Six knees were converted to TKA because of their persistent knee pain. Twenty-eight knees complained of night pain pre-operatively, but only four of them complained of it postoperatively

Considering that most of the patients in this series were grade IV in x-rays and their joint surface of medial compartment showed large eburnation both femur and tibia, TKA is most preferable treatment conventionally. But our results showed this arthroscopic technique was one of the applicable choices for severe OA knees.