Background

In vivo evaluation of IVD strains is crucial to better understand normal and pathological IVD mechanics, and to evaluate the effectiveness of treatments. This study aimed to 1) develop a novel in vivo technique based on 3T MRI and digital volume correlation (DVC) to measure strains within IVDs and 2) to use this technique to resolve 3D strains within IVDs of healthy volunteers during extension.

Principles of bone preservation and restoration of biomechanical alignment should be followed during revision total hip arthroplasty (THA). Where possible, conservative femoral revision techniques and even reconstructive de-escalation involving using primary stems should be considered. This study aims to investigate the outcome of patients who have undergone conservative femoral revision THA in our Institution.

We retrospectively identified patients from our Institution's revision arthroplasty database who had cemented, or un-cemented primary stems implanted during revision THA of a previous stemmed femoral implant. Our primary outcome measure was all-cause re-revision THA with a secondary outcome measure of improvement in Oxford hip score (OHS). Radiographic evidence of stem loosening and post-op complications were recorded.

Between 02/12/2014 to 12/12/2019, there were 226 patients identified with a mean follow up of 2 years (1–5 years). The majority of cases were represented by Paprosky type 1 (63%) and type 2 (25%) femoral defects. There were 45 patients (20%) who underwent impaction bone grafting (IBG) and 43 patients (19%) who had a cement in cement (CinC) femoral revision and cemented primary stem in 137 (60%), 1 uncemented stem with no IBG or CinC revision. Kaplan Meier survival for all-cause re-revision THA was 93.7% (95% CI: 88.3 – 100) at 3 years. The reasons for re-revision included 4 periprosthetic fractures, 4 dislocations, 1 deep infection, 1 loosening of femoral component and 1 loosening of acetabular component. Pre- and post-operative OHS scores were available in 137 hips (60%) with a mean improvement of 13. Radiographic review revealed 7% of cases with evidence of loosening in 1 or more Gruen zones.

Our early results support the use of conservative femoral revision THA techniques where appropriate, with low complication and re-revision rates. Revisions using primary femoral components, where appropriate, should be considered in surgical planning to avoid unnecessary reconstructive escalation.

Trabecular metal (TM) augments are designed to support an uncemented socket in revision surgery when adequate rim fit is not possible. We have used TM augments in an alternative arrangement, to contain segmental defects to facilitate impaction bone grafting (IBG) and cementation of a cemented socket. However, there is a paucity of literature supporting the use of this technique. We present one of the largest studies to date, reporting early outcomes of patients from a tertiary centre.

A single-centre retrospective analytical study of prospectively collected data was performed on patients who had undergone complex acetabular reconstruction using TM augments, IBG and a cemented cup. All patients operated between 2015 and 2019 were included. We identified 105 patients with a mean age of 74yrs. The mean follow-up was 2.3 years(1–5.5yrs). Our primary outcome measure was all-cause revision of the construct. The secondary outcome measures were, Oxford hip score (OHS), radiographic evidence of cup migration/loosening and post-op complications.

Eighty-four out of 105 patients belonged to Paprosky grade IIb, IIc or IIIa. Kaplan-Meier survivorship for all-cause revision was 96.36% (CI, 90.58–100.00) at 2 years with 3 failures. Two were due to early infection which required two-stage re-revision. The third was due to post-operative acetabular fracture which was then re-revised with TM augment, bone graft and large uncemented cup. Pre-op and post-op matched OHS scores were available for 60 hips(57%) with a mean improvement of 13 points. Radiographic analysis showed graft incorporation in all cases with no evidence of cup loosening. The mean vertical cup migration was 0.5mm (Range −5 to 7mm). No other complications were recorded.

This study shows that reconstruction of large acetabular defects during revision THA using a combination of TM augments to contain the acetabulum along with IBG to preserve the bone stock and a cemented socket is a reliable and safe technique with low revision rates and satisfactory clinical and radiographic results. Long term studies are needed to assess the possibility of preservation and regeneration of bone stock.

Scoliosis surgery has moved towards all posterior correction, as modern implants are perceived to be powerful enough to overcome stiffer and more severe curves. However, shortening of the anterior spinal column remains most effective in creating thoracic kyphosis, and may still have a role in correcting both coronal and sagittal deformities. Furthermore, anterior correction of lumbar and thoracolumbar curves can theoretically reduce the distal fusion level, and may have significant impact on patients' post-operative function.

A single surgeon series of 62 patients with idiopathic scoliosis were examined retrospectively. Radiographs and operation notes were examined by 2 spinal surgeons, sagittal and coronal parameters were measured before and after the operation. The patients were divided into 4 groups: 16 anterior and posterior fusions (AP), 16 anterior thoracolumbar fusions (A), 5 anterior thoracic releases and posterior fusions (AR), and 25 posterior fusions only (P).

The mean age was 15.3 (range 10 – 20). The mean main thoracic Cobb angle pre-operatively was: 54° (AP), 43° (A), 63° (AR), and 50° (P). The mean thoracolumbar Cobb angle was: 55° (AP) and 51° (A). There was no significant difference in lumbar lordosis.

The mean post-operative main thoracic Cobb angle was: 9° (AP), 13° (A), 9° (AR) and 15° (P). There was significant difference between AR and P groups. The mean post-operative thoracolumbar Cobb angle was: 8° (AP) and 6° for (A). There was a significant difference in the post-operative thoracic kyphosis between AP (mean 14°), A (mean 38°), AR (mean 19°) and P (mean 14°). Overall, the lumbar lordosis for all 4 groups reduced from a mean of 67° to 50°, with no significant difference between the groups.

The distal level of fusion for A and AP groups were L3 for all cases, whereas 2 cases had to extend to L4 in the P group.

Anterior release improved both coronal and sagittal correction when compared to posterior only surgery, however it is of unknown clinical significance. Anterior thoracolumbar fusion with or without posterior spinal fusion appeared to produce adequate coronal correction if fused to L3. No difference was found between all groups in post-operative lumbar lordosis.

There is a wide range of reports on the prevalence of neurological injuries during scoliosis surgery, however this should depend on the subtypes and severity of the deformity. Furthermore, anterior versus posterior corrections pose different stresses to the spine, further quantifications of neurological risks are presented.

Neuromonitoring data was prospectively entered, and the database between 2006 and 2012 was interrogated. All deformity cases under the age of 21 were included. Tumour, fracture, infection and revision cases were excluded.

All “red alerts” were identified and detailed examinations of the neuromonitoring records, clinical notes and radiographs were made. Diagnosis, deformity severity and operative details were recorded.

2290 deformity operations were performed: 2068 scoliosis (1636 idiopathic, 204 neuromuscular, 216 syndromic, and 12 others), 89 kyphosis, 54 growing rod procedures, and 80 operations for hemivertebra. 696 anterior and 1363 posterior operations were performed for scoliosis (8 not recorded), and 38 anterior and 51 posterior kyphosis correction.

67 “red alerts” were identified, there were 14 transient and 6 permanent neurological injuries. 62 were during posterior stage (24 idiopathic, 21 neuromuscular, 15 syndromic (2 kyphosis), 1 growing rod procedure, 1 haemivertebra), and 5 were during anterior stage (4 idiopathic scoliosis and 1 syndromic kyphosis). Average Cobb angle was 88°. 1 permanent injuries were during correction for kyphosis, and 5 were for scoliosis (4 syndromic, 1 neuromuscular, and 1 anterior idiopathic).

Common reactions after “red alerts” were surgical pause with anaesthetic interventions (n=39) and the Stagnara wake-up test (n=22). Metalwork was partially removed in 20, revised in 12 and completely removed in 9. 13 procedures were abandoned.

The overall risk of permanent neurological injuries was 0.2%, the highest risk groups were posterior corrections for kyphosis and scoliosis associated with a syndrome. 4% of all posterior deformity corrections had “red alerts”, and 0.3% resulted in permanent injuries; compared to 0.6% “red alerts” and 0.3% permanent injuries for anterior surgery. The overall risk for idiopathic scoliosis was 0.06%.

Aims:

Identifying and scoring risk factors that predict early wound dehiscence and progression to metalwork infection. Results of wound healing, eradication of infection and union of with the use of vacuum dressing. Compare results of serial washouts against early vacuum dressing in this group of children with significant medical co-morbidities.

PURPOSE

This study aims to identify the incidence and factors influencing readmissions following scoliosis surgery over a period of 19 years.

The Orthopaedic Unit at The Alfred has been using an external fixator in a novel configuration for protecting lower limb wounds after free flap surgery (sometimes even in the absence of a concomitant bony injury). This soft-tissue frame allows the limb to be elevated without contact so that there is no pressure on the flap and its pedicle. Thus, optimising the arteriovenous circulation. We report our initial experience with these soft tissue frames.

The soft tissue frame is not necessarily applied for definitive fracture care, but constructed or modified to optimise elevation of the leg, remove direct pressure from the soft tissues, and stabilise the muscles adjacent to the flap. All ankle-spanning frames held the foot in a plantargrade position to optimise blood flow and recovery (prevent equinus), and minimise intra-compartmental pressure.

During 2007, the Plastic Surgery Unit performed 23 free flaps to the lower limbs of 22 patients. Five of these patients had a soft-tissue frame constructed. One patient had a frame applied purely to manage the soft tissue injury, and the other four, who required an external fixator for a bony injury, had their frame modified. Four of the five patients study patients were injured in motor vehicle accidents and one was injured in a simple fall. All five free flaps survived and none required any further surgery. No patients suffered complications (such as bleeding, pin-track infections, or osteomyelitis) related to the soft tissue frame.

We strongly recommend considering an external fixator in a modified configuration after lower limb free flap surgery. Constructing a soft tissue frame has no added risks if the fixator is already required. In the case where there is no bony injury, a soft tissue frame has the benefits of providing optimal flap conditions and maintaining anatomical joint alignment. However, this must be balanced against the small risk associated with the insertion of pins (such as infection) and the need for an extra procedure to remove the frame. As always, treatment must be tailored to the individual patient.

Purpose

This study aims to identify factors that influence the Cobb angle at presentation to a tertiary referral scoliosis centre, and the outcome of the referrals.

Introduction: Anterior convex epiphysiodesis and posterior concave distraction has not been previously described in the literature for the treatment of thoracolumbar hemivertebrae. We describe our experience with long-term follow-up.

Method: Six consecutive patients with a mean age of 3.4 years were operated on with this technique. Levels of fusion extended two levels above and below the hemi-vertebra, while the instrumentation span the full length of the curve. Further concave distraction was carried out when there was evidence of loosening of the hooks.

Results: The average follow-up was 10.8 years (range 8 to 14). The mean Cobb angle before surgery was 49°, and at the latest follow-up was 26°. There was a mean 41% improvement in the scoliosis. In 5 of these cases, this correction was achieved immediately after surgery and did not significantly change despite repeated distraction.

Conclusion: The addition of concave distraction provided better correction than convex epiphysiodesis alone. It is technically easier and safer than hemivertebra excision in the correction of such deformities. This method of treatment is recommended for patients with single fully segmented hemivertebrae located at the thoracolumbar junction that has a significant deformity.

Introduction: Anterior convex epiphysiodesis and posterior concave distraction has not been previously described in the literature for the treatment of thoracolumbar hemivertebrae. We describe our experience with long-term follow-up.

Methods: Six consecutive patients with a mean age of 3.4 years were operated on using this technique. The levels of fusion extended two levels above and below the hemivertebra, while the instrumentation spanned the full length of the curve. Further concave distraction was carried out when there was evidence of loosening of the hooks.

Results: The average follow-up was 10.8 years (range: eight to 14 years). The mean Cobb angle before surgery was 49 degrees, and at the latest follow-up was 26 degrees. There mean improvement in the scoliosis was 41%. In five of these cases, this correction was achieved immediately after surgery and did not significantly change despite repeated distraction.

Conclusions: The addition of concave distraction provided better correction than convex epiphysiodesis alone. This method of treatment is recommended for patients with single fully segmented hemivertebrae located at the thoracolumbar junction associated with a significant deformity. This method is technically easier and safer than excision of the hemivertebra in the correction of such deformities.

The FBCI has been shown to be a better method for describing scoliosis correction because it takes spinal flexibility into consideration. 1

Objective: To use FBCI prospectively to compare the efficacy of four different posterior instrumentations in the correction of thoracic scoliosis.

Method: 123 idiopathic scoliosis patients with thoracic curves were surgically treated prospectively using 4 different posterior instrumentations: TSRH (n=35); ISOLA (n=33); CD-Horizon (CD-H: n=32); and Moss-Miami (MM: n=23). All the operations were performed by the same team of surgeons using standard techniques. The curve was measured using the Cobb’s method on the pre-operative PA standing, fulcrum bending and 1-week post-operative PA standing radiographs. The conventional correction rate and the FBCI were calculated. One-way ANOVA and independent sample t-test were used for statistical analysis.

Results: (1) There were no significant differences between any of the 4 instrumentations when assessed using the FBCI, however, the correction rate was better in CD-H than in ISOLA and TSRH (Table 1). (2) Higher FBCIs were observed in the stiff curve group (fulcrum flexibility £ 50%) compared with those in the flexible group (fulcrum flexibility > 50%), while the correction rates were lower in the former than in the latter (Table 2).

Discussion: Better correction rate obtained in the CD-H group was attributed to the more flexible curves rather than the instrumentation itself. In the flexible curve group, the instrumentations have been able to take up all the flexibility revealed by the fulcrum-bending radiograph. Although the correction rate was less in the stiff curve group, the FBCI showed that the deformity correction was actually more than that indicated by the fulcrum bending radiographs. One possible explanation of this phenomenon may be that the fulcrum-bending radiograph is less effective in eliciting all the flexibility in the stiff curves.

Conclusion: All 4 instrumentations were EQUALLY effective in correction of thoracic scoliosis when the curve flexibility was taken into consideration.

In scoliosis, it is well known that lateral deformity is coupled with vertebral axial rotation. Coupled motion in the sagittal plane, however, has not been investigated.

Objective: To investigate the behavior of the sagittal alignment changes when coronal deformity was corrected in idiopathic thoracic scoliosis.

Method: 36 idiopathic scoliosis patients with thoracic curves were examined before surgery. Coronal deformity was corrected using the Fulcrum Bending technique1, and biplane radiographs were taken to monitor the correction of the deformity, as well as the coupled sagittal alignment changes. Sagittal alignment was measured from T4/T5 to T12 using Cobb’s method. Difference of less or equal to 3 degrees between two measurements was treated as no change. Results were compared with those measured from standing lateral radiographs prior to and at 1 week after surgery (Posterior correction and fusion with ISOLA: n=15; CD-Horizon: n=8; Moss-Miami: n=11, USS: n=2). Pearson correlation was used for statistical analysis.

Results: (A) When scoliosis was corrected under fulcrum bending, the coupled changes in the thoracic kyphosis were decreased if it was greater than 20 degrees (n= 18), increased if less than 20 degrees (n= 2), and kept no change if it was around 20 degrees (n= 16). These changes were not related to the amount of deformity or flexibility in the coronal plane (Table I). (B) There was strong relationship between the sagittal alignment measured on the pre-operative fulcrum bending and postoperative lateral radiographs (P< 0.01). However, the final sagittal alignment was neither correlated with the magnitude or flexibility of the coronal deformity, nor the instrumentation applied (P> 0.05)

Discussion: A coupling exists between the coronal lateral deformity and the sagittal alignment in thoracic scoliosis. It seems that the sagittal alignment in a scoliotic spine tends to “normalize” with correction of the deformity: a “hyper-kyphotic” spine tends to reduce, and a “hypo-kyphotic” one tends to increase the kyphosis. Post-operative sagittal alignment seems to be decided by the coupling motion and the amount of curvature of the pre-bent rod, as neither the nature (degree or flexibility or curve pattern) of the coronal deformity nor the choice of instrumentation were related to the post-operative sagittal alignment.