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Bone & Joint Open
Vol. 2, Issue 3 | Pages 191 - 197
1 Mar 2021
Kazarian GS Barrack RL Barrack TN Lawrie CM Nunley RM

Aims

The purpose of this study was to compare the radiological outcomes of manual versus robotic-assisted medial unicompartmental knee arthroplasty (UKA).

Methods

Postoperative radiological outcomes from 86 consecutive robotic-assisted UKAs (RAUKA group) from a single academic centre were retrospectively reviewed and compared to 253 manual UKAs (MUKA group) drawn from a prior study at our institution. Femoral coronal and sagittal angles (FCA, FSA), tibial coronal and sagittal angles (TCA, TSA), and implant overhang were radiologically measured to identify outliers.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_10 | Pages 18 - 18
1 Oct 2020
Nunley RM Barrack RL Lawrie CM
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Introduction

Modular dual mobility (MDM) prostheses are increasingly utilized for total hip arthroplasty (THA) to mitigate the risk of postoperative instability in high risk patients. Short-term reports on clinical outcomes are favorable but there are few studies on young active patients. This study quantified proximal femoral stress shielding and metal ion release in MDM combined with modern cementless stem design in young active patients.

Methods

This was a prospective study of patients between 18 and 65 years of age, with a body mass index (BMI) < 35 kg/m2 and University of California at Los Angeles (UCLA) activity score > 6, who received a modular cobalt-chromium acetabular liner, highly crosslinked polyethylene mobile bearing, and cementless titanium femoral stem for their primary THA. DEXA scans were performed at 6 weeks postoperatively as a baseline, then again at 6 months, 1 year, 2 years and 5 years postoperatively as were metal ions.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_9 | Pages 24 - 24
1 Oct 2020
Kazarian GS Barrack RL Barrack TN Lawrie CM Nunley RM
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Introduction

The purpose of this study was to compare the radiographic outcomes of manual versus robotic-assisted medial unicompartmental knee arthroplasty (UKA).

Materials & Methods

Postoperative radiographic outcomes from 86 consecutive robotic-assisted UKAs (RAUKA group) from a single academic center were retrospectively reviewed and compared to 253 manual UKAs (MUKA group) drawn from a prior study at our institution. Femoral coronal and sagittal angles (FCA, FSA), tibial coronal and sagittal angles (TCA, TSA), and implant overhang were radiographically measured to identify outliers. Clinical results at 4–6 weeks postoperative were compared to a control cohort of total knee arthroplasty (TKA) patients from our institution.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_9 | Pages 69 - 69
1 Oct 2020
Lawrie CM Barrack RL Nunley RM
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Introduction

Bone mineral density (BMD) is correlated with component migration and aseptic loosening after total knee arthroplasty (TKA). Older implant designs have demonstrated BMD loss up to 23% in the first 6 months after TKA, and continued to BMD decline at an average of 5% per year for as long as 2 years after TKA. The impact of component design and fixation method on BMD loss after TKA in modern implant designs has not been fully elucidated. The purpose of this study is to determine the effect of tibial tray thickness and fixation method (cemented versus cementless) on BMD loss patterns of the proximal tibia in two different modern TKA implant systems

Methods

A prospective, nonrandomized, single center study of patients undergoing primary TKA by one of two surgeons was performed with four study cohorts: cemented DePuy Attune, cementless DePuy Attune, cemented Stryker Triathlon, cementless Stryker Triathlon. Target sample size was 80, with 20 per cohort based on adhoc power analysis. Exclusion criteria included: age over 75, BMI >40, inflammatory arthritis, previous knee surgery involving the femur, tibia or tibial bone, and diagnosis of osteopenia/osteoporosis. Implant fixation type was based on surgeon intraoperative assessment of patient bone quality. Demographic data was collected preoperatively. Dual Energy X-ray Absorptiometry (DEXA) Bone Density Monitoring was performed at 6 weeks and one year postoperatively. Bone mineral density was calculated from the DEXA scans for 4 zones for the tibia relative to the keel or central peg: anterior, posterior, medial and lateral. Results were reported as BMD at 1 year postoperatively as a percentage of BMD at 6 weeks postoperatively.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_11 | Pages 4 - 4
1 Oct 2019
Lawrie CM Okafor LC Kazarian GS Barrack TN Barrack RL Nunley RM
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Background

The purpose of this study was to assess the overall clinical and radiographic outcomes of unicompartmental knee arthroplasty (UKA) in the 2–10 year postoperative period. The secondary goal was to compare outcomes between fixed- (FB) and mobile-bearing (MB) implant designs.

Methods

We performed a retrospective analysis of 237 consecutive primary medial UKAs from a single academic center. All cases were performed by high-volume fellowship-trained arthroplasty surgeons, though UKA comprised <10% of their overall knee arthroplasty practice (<20 medial UKAs per surgeon per year). Clinical outcomes included the Oxford Knee Scores (OKS) and revision rates. Femoral and tibial coronal and sagittal angles (FCA, FSA, TCA, TSA) were radiographically measured. FCA (>±10º deviation from the neutral axis), FSA (>15º flexion), TCA (>±5º deviation from the neutral axis), and TSA (>±5º deviation from 7º) outliers were defined. Far outliers were defined as measurements that fell an additional >±2º outside of these ranges. Outcomes were compared between the FB and MB groups.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_11 | Pages 34 - 34
1 Oct 2019
Lawrie CM Jo S Barrack TN Barrack RL
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Introduction

Periprosthetic infection (PJI) after primary total knee arthroplasty (TKA) remains a challenging issue affecting 1–2% of cases. Locally delivered prophylactic antibiotics, including tobramycin or gentamicin mixed in polymethylmethacrylate (PMMA) bone cement and vancomycin powder, are increasingly used despite a lack of high quality evidence for either practice. In this study, we report the antibiotic susceptibility of organisms recovered in culture from patients with acute prosthetic joint infection after primary TKA to gentamicin, tobramycin and vancomycin.

Methods

Using a retrospective database of all primary TKA performed at a single institution between January, 1 2014 and July 1, 2018, we identified 18 cases of acute PJI after primary TKA, as defined by the Musculoskeletal Infection Society 2011 guidelines as less than 3 months from symptoms or index surgery to presentation. The use of antibiotic bone cement during the index procedure and time to surgical management of the infection were recorded. Fluid cultures and tissue cultures were obtained intraoperatively at the time of revision. The organisms from positive cultures underwent MIC testing to gentamicin, tobramycin and vancomycin using a gradient diffusion method (ETEST). MIC breakpoints for susceptibility were based on Clinical and Laboratory Standards Institute definitions.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_12 | Pages 23 - 23
1 Oct 2019
Lawrie CM Barrack TR Abu-Amer W Adelani MA Clohisy JC Barrack RL Nunley RM
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Introduction

The utility and yield of the current practice of routine screening of asymptomatic patients after primary total hip arthroplasty (THA) and total knee arthroplasty (TKA) is unclear. The purpose of this prospective survey study was to determine the utility of the routine on year follow up visit primary THA and TKA.

Methods

We prospectively enrolled all patients undergoing primary THA and TKA. At one-year follow-up, patients were asked to complete a survey that asked about satisfaction with the and if they thought the visit was worthwhile. Surgeons also completed a survey which asked if any intervention was done, if any problems were diagnosed/avoided, and if the visit was worthwhile. Data was analyzed and compared between patients and surgeons, and was also compared to the need for any additional interventions


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_12 | Pages 8 - 8
1 Oct 2019
Lawrie CM Schloemann D Kazarian GS Barrack TN Barrack RL
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Background

The aim of this study was to determine the change in standing pelvic sagittal alignment and associated impact on functional acetabular component position at follow-up after total hip arthroplasty (THA).

Patients and Methods

A retrospective review was performed on 91 consecutive patients who had undergone primary THA by a single surgeon via a posterior approach in the lateral decubitus position. Of these, 41 patients had high quality standing AP pelvis radiographs preoperatively, at six weeks postoperatively, and at one year postoperatively available for analysis. Pelvic ratio was defined as the ratio between the vertical distance from the inferior sacroiliac (SI) joints to the superior pubic symphysis and the horizontal distance between the inferior SI joints. Apparent changes in the functional acetabular component position were determined from the change in pelvic ratio between the preoperative and one year postoperative standing AP pelvic radiograph. A change of at least five degrees was considered clinically meaningful.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 29 - 29
1 Oct 2018
Lawrie CM Schwabe M Pierce A Barrack RL
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Introduction

Cemented total knee arthroplasty (TKA) remains the gold standard with survivorship above 90% at greater than 10 years postoperatively. However, with younger, heavier, more active patients undergoing TKA at an increasing rate, cementless implants have the appeal of potential for improved implant fixation longevity and decreased rates of aseptic loosening. The cementless implants are more expensive than their cemented counterparts such that implant costs may create a barrier to utilization. However, such comparisons fail to consider the unavoidable additional costs of cementing, including the cost of operating room time, cement and cementing accessories. The purpose of this study is to compare the actual cost of cemented and cementless TKA.

Methods

The TKA cost calculation included the cost of operative time, implants, cement and cementing accessories. The difference in operative time between cemented and cementless TKA was determined from a previously published study of 100 TKAs performed using a cemented (55) or press fit (45) implant of the same design performed at a single institution by four fellowship trained arthroplasty surgeons. The decision to use cemented or cementless design in these patients was made based on patient bone quality intraoperatively. Operative time was compared between groups using a Student's two-tailed T-test. The cost of operating room time was based on estimates in the recent literature. The cost of cement and cementing accessories was estimated based on publically available market data. The cost of implants was estimated from institutional data for multiple companies.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 19 - 19
1 Oct 2018
Kazarian GS Barrack TN Donaldson MJ Lawrie CM Miller GA Haddad FS Barrack RL
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Introduction

Implant malalignment is an important predictor of prosthetic failure following total knee arthroplasty (TKA). The purpose of this study was to determine the incidence of outliers for common alignment targets and the impact of surgeon volume and experience on the accuracy of implant alignment with current generation manual instrumentation.

Methods

This study was a retrospective, multi-center, radiographic analysis of 1675 consecutive primary uncomplicated TKAs from seven surgeons at three academic and state-funded centers in the US and UK. Surgeons were categorized as “high-volume” (≥50 TKAs/year) and “high-experience” (≥5 years post-fellowship). Femorotibial, tibial varus/valgus, and posterior tibial slope angles were digitally measured using postoperative radiographs. Femorotibial (<2° or >8° valgus), tibial (> ±3° deviation from the neutral axis), and tibial slope (<0° or >7° of flexion for cruciate retaining, <0° or >5° of flexion for posterior stabilized) angle outliers were identified. The proportion of outliers among surgeons in each subgroup was compared.