Background

Trunk muscles play an important role in supporting the spinal column. A decline in trunk muscle mass, as measured by bioelectrical impedance analysis (TMM–BIA), is associated with low back pain and poor quality of life.

Introduction

Peri-articular local anesthetic injections reduce post-operative pain in total knee arthroplasty and assist recovery. It is inconclusive whether intra-operative injection of peri-articular morphine is locally effective. The aim of this study is whether the addition of morphine to peri-articular injections in only unilateral knee improves post-operative pain, range of motion, swelling in patients with simultaneous bilateral total knee arthroplasty.

[Purpose]

There have been only a few reports about the efficacy of postoperative cryotherapy following total hip arthroplasty (THA), and past studies have described that local cooling is efficacy for pain relief. The purpose of this study is whether the continuous local cooling following THA is effective for pain relief and the reduction of blood loss, swelling, and the duration of hospital stay.

[Introduction]

Surgical-site-infections (SSI) prolong hospital stay, and they are leading nosocomial cause of morbidity and a source of excess cost. Recently, a waterless hand-rubbing protocol containing aqueous 1% chlorhexidine gluconate was developed before surgery, but there is no literature in orthopaedic surgery. The aim was to compare the SSI rates between waterless hand-rubbing and traditional hand-scrubbing protocol.

Over the past decade, there has been an increase in the number of total knee arthropalsty (TKA). Demand of TKA for the young patients who often have high physical demands is also increasing. However, the revision rate in such young patients is much higher due to polyethylene (PE) wear and instability (Julin J, Acta Orthop 2010). Therefore, next generation total knee prostheses are expected to decrease PE wear and to provide stability.

Although in vitro study such as wear simulator test provides important information about PE wear, we have often encountered the discrepancy between the in vitro results and in vivo results. Thus we have performed in vivo PE wear particle analysis, and showed that in vivo PE wear was affected by the design of articulating surface and the materials of femoral component and PE insert (Minoda Y, JBJS Am 2009). Medial pivot design, ceramic femoral component, and highly cross-linked PE decreased in vivo PE wear particle generation.

Patients who underwent bilateral staged TKAs were more likely to prefer medial pivot prosthesis or ACL-PCL retaining prosthesis than the other types of prostheses, because they feels “more stable overall” (Pritchett JW, J Arthroplasty 2011). In vivo fluoroscopic 3D analysis showed that medical pivot and bi-cruciate substituting designs restored physiological knee motion and provided higher reproducibility (Mueller J. Komistek RD, Trans ORS 2009, Iwakiri K, Trans ORS 2007).

The excellent mid-term clinical results of those newly introduced total knee prosthesis, such as alumina medial pivot TKA (Iida T, ORS 2008), medial pivot TKA (Mannan K, JBJS Br 2009, Kakachalions T, Knee 2009), ACL-PCL retaining TKA (Clouter JM, JBJS Am 1999), and highly cross-linked PE (Hodrick JT, CORR 2008), have been reported.

From the point of view of in vivo PE wear, in vivo stability, and the mid-term clinical results, we suspect that medial pivot prosthesis is one of the prostheses which meet the demand in future especially for young active patients.

Introduction: Preoperative planning is an important part of the total knee arthroplasty(TKA) surgical procedure.

In joint arthroplasty, the use of a templating system has been recommended and it is routinely used with most designs. The aim of this study was to compare the accuracy of preoperative templating in TKA between conventional two-dimensional (2D) and computed tomography (CT)-based 3D procedures in order to confirm the necessity of using 3D evaluations for preoperative planning.

Method: One-hundred consecutive primary TKAs performed during the period between December 2005 and May 2009 were analyzed. The mean age of the patients was 73.3 years (range, 33 to 90 years). Preoperative templating was performed for each TKA using both conventional 2D radiographs (both anteroposterior and lateral views) which were analyzed by a single senior surgeon. Preoperative CT scans of the knee were performed and a CT-based 3D image model (superimposing the computer aided design model of the implant) was generated using KneeCAS (KneeCAS: Knee Computer-Assisted System) and then was analyzed by a radiology technologist without any knowledge of the 2D procedure. Based on the operation notes, we determined which size implant had been inserted at the time of surgery and used this as the gold standard. The accuracy and reliability were assessed for all measurements of the two different templating procedures (2D and CT-based 3D procedures)

The Chi-square test for independence for paired observations was used to analyze the accuracy. The weighted kappa test was used to analyze reliability.

Results: 56% of the 2D procedures were found to be an exact match. This increased to 98% for the template sizes within one size above or below that used and 2% were two sizes or more adrift. Otherwise, 59% of the CT-based 3D procedures were an exact match; 98% were within one size and 2% were two sizes or more adrift. The CT-based 3D procedure was slightly more accurate than the 2D procedure. However, the difference was not statistically significant (p = 0.67). The weighted kappa coefficient of the 2D procedure was 0.49 (which indicates a moderate agreement), while that of the CT-based 3D procedure was 0.49 (which indicates a moderate agreement). The results of the weighted kappa coefficients were not statistically significant (p = 0.65).

Conclusion: Computer-assisted surgery systems are used often for preoperative planning in TKA. However, our results do not support the superiority of 3D preoperative templating to 2D conventional evaluation in predicting implant size. Thus, 3D templating may not be necessary for preoperative planning in TKA.

The introduction of porous tantalum metal (Trabecular Metal; Zimmer, Warsaw, IN) for acetabular component fixation in total hip arthroplasty has shown optimum fixation qualities and “gap filling” effect. Recently, trabecular metal was introduced in tibial component for total knee prosthesis, however its effect on the bone mineral density (BMD) was not reported. The purpose of this study was to compare the BMD of proximal part of the tibia between trabecular metal and another cemented tibial component.

31 knees receiving trabecular metal tibial component and 33 knees receiving cemented tibial component (PFC Sigma RP, Depuy, Warsaw, IN) had dual energy x-ray absorptiometry (DEXA) scans at preoperatively and 3 weeks, 3, 6, 12, 18, 24 months post-operatively. To assess peri-prosthetic BMD, three regions of interest (ROI) were measured for each case. They were medial aspect (ROI 1), center aspect (ROI 2) and lateral aspect (ROI 3) of tibia. Average follow up period was 1.8 (range: 1.5 to 2) years. In both groups, BMD in tibia decrease postoperatively. Comparing postoperative decrease of BMD in lateral aspect of tibia (ROI 3) between both groups, it was significantly less in trabecular metal component (−0.09 g/cm2 +/−0.27) than cemented tibial component (−0.31 g/cm2 +/− 0.21) (p=0.0007).

We conclude that trabecular metal tibial component showed a favorable effect on BMD of proximal part of the tibia after total knee arthroplsaty.

Highly closslinked polyethylene has been developed to reduce polyethylene wear and to expect the longevity of THA. In daily activity of patients, total hip prostheses repeatedly suffer impact loading. However, the mechanical properties, especially impact load transmission, are not well investigated and the viscoelasticity might influence the loosening of cemented all-polyethylene cup. In this study, the impact load transmission through the complex of polyethylene cup, ceramic ball and metallic femoral stem was investigated.

Impact compressive tests on the complex were performed using Hopkinson pressure bar apparatus. Conventional and highly crosslinked polyethylene cups of three different sizes (40mm, 50mm, 56mm)were compared. The impact load was applied either from the cup or from the stem. The impact load transmission ratio (ILTR) i.e. the ratio of the magnitude of transmitted load to that of incident one was investigated. The loading pulse profiles were theoretically calculated based on the one dimensional elastic wave propagation theory and were compared with experimental results.

The ILTR was independent of the cup size in all experimental conditions. When the impact load was applied from the cup, the ILTR was not different between two types of polyethylene. On the other hand, when the impact load was applied from the stem, the ratio was greater than the previous loading condition, while the ratio of crosslinked polyethylene was significantly lower than that of conventional one (p < 0.05). The theoretically predicted stress pulse profiles were well correlated to the experimental ones.

The lower ILTR in highly crosslinked polyethylene is considered to be due to lower stiffness. These mechanical properties increase the deformity of the cup and may cause the loosening of the cup. These results indicated that the ILTR was not different among cup sizes, while the ratio was significantly affected by the loading conditions and the type of polyethylene.

Highly crosslinked polyethylene has been developed to reduce polyethylene wear and to expect the longevity of THA. In daily activity of patients, total hip prostheses repeatedly suffer impact loading. However, the mechanical properties, especially impact load transmission, are not well investigated and the viscoelasticity might influence the loosening of cemented all-polyethylene cup. In this study, the impact load transmission through the complex of polyethylene cup, ceramic ball and metallic femoral stem was investigated.

Impact compressive tests on the complex were performed using Hopkinson pressure bar apparatus. Conventional and highly crosslinked polyethylene cups of three different sizes (40mm, 50mm, 56mm) were compared. The impact load was applied either from the cup or from the stem. The impact load transmission ratio (ILTR) i.e. the ratio of the magnitude of transmitted load to that of incident one was investigated. The loading pulse profiles were theoretically calculated based on the one dimensional elastic wave propagation theory and were compared with experimental results.

The ILTR was independent of the cup size in all experimental conditions. When the impact load was applied from the cup, the ILTR was not different between two types of polyethylene. On the other hand, when the impact load was applied from the stem, the ratio was greater than the previous loading condition, while the ratio of crosslinked polyethylene was significantly lower than that of conventional one (p < 0.05). The theoretically predicted stress pulse profiles were well correlated to the experimental ones.

The lower ILTR in highly cross linked polyethylene is considered to be due to lower stiffness. These mechanical properties increase the deformity of the cup and may cause the loosening of the cup. These results indicated that the ILTR was not different among cup sizes, while the ratio was significantly affected by the loading conditions and the type of polyethylene.

Acetabular revision in patients with bone deficiency is often difficult because of the poor quality and quantity of the acetabular bone stock. The purpose of this study was to evaluate the midterm clinical and radiographic outcomes of acetabular revision with use of an impaction bone-grafting technique and a cemented polyethylene cup.

Results: thirty consecutive acetabular revisions were performed with impaction bone-grafting and use of a cemented cup in twenty-eight patients with bone deficiency. The average age at the revision was sixty-eight years. The minimum duration of follow-up of all reconstructions that were still functioning or that were followed until the time of death was three years (mean, 8.1 years; range, three to fifteen years). The acetabular bone defects were classified as cavitary in fifteen hips and as combined segmental-cavitary in fifteen hips according to AAOS classification.

One hip had a repeat revision. Radiographic analysis that had not been revised showed loosening in four hips. All these four hips were treated by bulk bone graft covering more than 50% of cups. Kaplan-Meier analysis demonstrated a prosthetic survival rate, with aseptic loosening as the end point, of 72% at fourteen years and, with revision as the endpoint, of 100% at ten years and 83% at fourteen years.

Impaction bone-grafting was an excellent option to manage acetabular revision surgery. However, excessive bulk bonegraft should not be used.

Introduction: Recently, highly cross-linked polyethylene has been highlighted in THAs, which is thought to reduce wear. However, little is known about an accurate nature of cross-linked polyethylene particles and long term wear in vivo. One of the authors implanted all polyethylene cups irradiated by 100 Mrad in 1970’s. Recently, we performed two revisions with this cup. In the present study, we extracted polyethylene particles and analyzed them.

Methods: Case1 was revised for a stem fracture and ace-tabular loosening at 25 years postoperatively and case2 for acetabular loosening at 27 years postoperatively. There was no osteolysis on X rays. We extracted polyethylene particles using a tiussue digestion and iamge analysis using computed iamge analyzer developed by Cambell.

Results: Equivalent circle diameter (ECD) was 0.73mm, roundness was 0.69, aspect ratio (AR) was 1.4 and number of particles was 6.0x108/g wet tissue in case1. ECD was 0.57mm, roundness was 0.62, AR was 1.54 and number of particles was 5.8x108/g in case2. SEM showed that granule or globular shapes were abundant and fibril shapes were rare.

Discussion and conclusion: Cross-linked polyethylene particles were less, a little smaller and much rounder in compared with our previous result of conventional polyethylene particles in peri-implant tissue after more than 25 years postoperatively in vivo.

Impaction allografting is one of the techniques for reconstruction of femur during revision total hip arthroplasties. The initial stability of the stem fixed with impacted morsellized allogtafts and cement depends on multiple factors. The aim of this study was to investigate the stability of stem in reference to the size of bone chips, femoral bone defect and implant design.

Morsellized grafts of human femoral heads were prepared using a reciprocating type bone mill or a rotating type bone mill. Femoral bone defect was created at proximal medial cortex. Two types of polished stem were tested; CPT stem and VerSys CT stem (Zimmer Inc.). The cross section of the stem was relatively rectangular in CPT stem, while round in VerSys CT stem. Morsellized grafts were impacted into an over-reamed plastic bone and the stem was fixed with PMMA bone cement. Cyclic compression test and torsional test were performed using an Instron type machanical tester. Bone chips prepared by a reciprocating type bone mill contained large chips with broad size distribution, which represented high stiffness in compression test and high maximum torque in torsional test. Femoral bone defect and implant geometry did not affect the axial stability of stem, while large bone defect and round shape stem showed significantly lower maximum torque.

These results indicated that the size of bone chips, femoral bone defect and implant geometry affected the initial stability of the stem. Impaction grafting seems to be a technically demanding procedure, however several factors can be controlled to obtain secure implant stability.

As for the number of patients who requires total knee arthroplasty (TKA), Asian-Pacific countries will be the most important market. However, due to the paucity of anthropometric data on the proximal tibia in this population, many prostheses designed for Caucasian knees have been introduced without specific modification.The aim of the current study was to analyze the geometry of the proximal tibia to design the optimum component for the Japanese population.

Anthropometric data on the proximal tibia of 100 knees in 80 patients undergoing TKA was obtained. Briefly, anterior-posterior (AP) and medial-lateral (ML) lengths were measured with a combination of two different methods, namely on the computed tomography (CT) images obtained preoperatively and intraoperative direct measurement on tibial resection surface. Reproducible measurement was possible only when the intraoperative measurement was combined with the corresponding CT images while the direction of measurements being aligned to the epicondylar axis of the femur.

It was shown that smaller components with an ML of around 60 mm were rarely required. Tibial component size variation should focus on an ML length of 65 to 75 mm because 76 of 100 knees (76 %) fell into this size range. When the subjects were confined to women, 70 of 77 knees (91%) were included in this size range. The intraoperative AP to ML ratio had a negative correlation with the ML length (r = −0.412, P < 0.0001) indicating that bigger knees were shallower in the AP direction. The size variation of currently popular pros-theses were not in accordance with the geometry of the tibial resection surface shown in this study.

The results of this study applied to a cross-section of the Japanese population can be used by manufacturers to create a prosthesis suitable for most of the Asian-Pacific population.

Introduction: The excellent character of cross-linked polyethylene on wear has been reported from basic researches. However, few clinical results were seen about irradiated polyethylene sockets. This presentation reports a long-term clinical result of irradiated polyethylene sockets.

Material and method: Two 100M-rad gamma irradiated polyethylene sockets were retrieved, each 25 and 27 years after implantation. Socket joint surface were scanned by 3-D scanner and analyzed. On the other hand, ten patients had total hip replacements with 6.5M-rad irradiated polyethylene sockets. Anterior-posterior and lateral radiograph were taken and the movement of the head to the socket was analyzed by 3-D wear measurement software GAWDI. The results were compared to conventional polyethylene sockets of matched patients.

Results: Wear of the 100M-rad sockets were 0.23mm/ 25yrs and 0.46mm/27yrs respectively. The direction of wear was observed over the whole surface. Wear of the conventional polyethylene socket retrieved 15yrs after implantation were 2.54mm/15yes and 1.76mm/12yrs. The wear were toward weight bearing directions.

The average movement of heads in 6.5M-rad irradiated polyethylene sockets was 0.22mm one year post operation and its direction was toward backside of patients’ body. The average movement of conventional polyethylene sockets was 0.24mm one year post operation and its direction was just the same as irradiated polyethylene sockets.

Discussion: The difference of long term results between 100M-rad irradiated polyethylene and conventional one was obvious. A definite wear path way was observed on conventional polyethylene sockets. However, it was ambiguous on 100M-rad irradiated polyethylene because it was small or it did not exist. No remarkable difference was observed in short term after operation between 6.5M-rad irradiated and conventional sockets. The present analysis suggests that a high dose irradiated polyethylene socket may benefit a good long-term clinical result.

The benefit of mobile-bearing mechanism in total knee arthroplasty (TKA) has been controversial. The aim of this paper is to analyse the rotation of polyethylene (PE) and its effect on the range of motion (ROM) in mobile-bearing, posterior stabilised TKA (LPS-Flex™, Zimmer Co. Ltd.).

Thirty-four consecutive PS-Flex™ TKAs (28 patients) were analysed. Three tantalum markers were inserted in the PE and the tibia (one for medial side and two for lateral side; total six markers). The rotation of the PE and the tibia was analysed in fluoroscopically-controlled radiograph taken at one years in full extension, 90 degrees flexion and passive maximum flexion. The markers in the tibia were identifiable in 19 knees and the analysis was based on these knees.

The tibia rotated internally relative to the femur by 7.1± 5.2 degrees (mean ± SD, range −1 to 20 degrees). The amount of tibial rotation has no correlation to ROM. The rotation of the PE relative to the femur was unpredictable showing three knees with external rotation and four knees without rotation (Average; 4.0 ± 4.5 degrees internal rotation). The rotation of the PE on the tibia was 4.2± 5.2 degrees and seven knees (37 %) showed no rotation and 12 knees (63 %) showed less than 5 degrees rotation. There was a positive correlation between the amount of PE rotation on the tibia and ROM, which approached to statistical significance (p = 0.0684).

This study has demonstrated that the rotation of the PE on the tibial tray is generally small (< 5 degrees). Because not tibial internal rotation but PE movement on the tibia correlated to ROM, the essential benefit of the mobile-bearing mechanism could be to compensate the rotational mismatch between the components rather than to reproduce normal knee kinematics.

The role of posterior cruciate ligament (PCL) in total knee replacement (TKR) has been a matter of debate for long time and remains controversial. In this study, the effect of posterior cruciate ligament (PCL) sacrifice on the tibiofemoral joint gap was analysed in 30 varus osteoarthritic knees undergoing posterior stabilized total knee replacement. Medial soft tissue was released and bone cut was made without preserving the bone segment of tibial PCL insertion. Then the medial and lateral joint gaps in full extension and 90□& lsaquo; flexion were measured before and after PCL sacrifice using a tensioning device (V-STAT tensor(tm), Zimmer). After PCL sacrifice, the flexion gap significantly increased both in medial and lateral side (4.8 □} 0.4 and 4.5 □} 0.4 mm respectively, mean □} SE) compared to those seen in the extension gap (0.9 □} 0.2 and 0.8 □} 0.2 mm, p < 0.001 ANOVA). There was no significant difference between the changes in the medial and lateral gap (p = 0.493). In conclusion, results of this intraoperative measurement showed that PCL sacrifice leads to a selective increase in the size of flexion gap by an average of 4.7 mm whereas it had little impact on the correction of varus deformity. These findings provided insights as for the role and necessity of PCL sacrifice in the correction of varus and flexion deformity. Because the flexion gap surpassed the unchanged extension gap during PCL sacrifice, PCL release could be used as a surgical technique to balance the gaps without additional bone cut.

The purpose of this paper is to emphasize lateral compartment arthroplasty as efficient method and to discuss postoperative problems by investigating mid-term results (over 5 years)

Two hundred and twenty two consecutive unicompartmental knee arthroplasties (UKA) were performed in our hospital between August 1977 and December 1999. Thirty eight joints of 37 patients underwent lateral UKA. There were 8 male and 29 female patients with an average of 65.1 years old. The following prostheses were used: Marmor in 5 patients, Oxford in 1, PCA in 11, and Omnifit in 21. Out of them, 24 joints had follow up over 5 years after replacement. Three patients died of unrelated illness and 3 were lost to follow up. The remaining 18 joints could be followed from 60 to 189 months (average, 99 months). The knee score of the Hospital for Special Surgery (the HSS knee score) was used for clinical evaluation.

Clinical results by the HSS knee score showed that 2 joints were judged as “good”, 13 as “fair”, and 3 as “poor” before surgery. After surgery 13 joints were improved to “excellent”, 3 to “good”, and 2 to “fair”. The two joints with fair results had revision surgery. In all, 16 joints had satisfactory results. With radiological evaluation, the average preoperative alignment on standing was 14.9o of valgus angulation and corrected to 6.9 o of valgus. Although radiolucent lines under the tibial component were not found, a radiolucent line was observed and extended to loosening in one femoral component. This patient was successfully revised to another type of UKA 3 years after the index surgery. In the medial compartment, we found slight deterioration of osteoarthritic change in 5 joints. Of these, one patient, needed medial UKA.

Lateral UKA is a reliable and successful option compared with other procedures in a patient with low level of physical activity, because the long-term results tend to last and loosening of the tibial components has not been observed as commonly as in medial UKA. However, deterioration of the medial compartment may occur. The alignment after surgery must be in slight valgus for a satisfactory long-term result.

The purpose of this study was to investigate the bone anatomy in determining the rotational alignment in total knee arthroplasty (TKA) using CT scan. Axial CT images of eighty-four varus osteoarthritic knees undergoing TKA were analysed. On the images of the distal femur and the proximal tibia, base line for anterior-posterior axis of each component was drawn based on the epicondylar axis for the femur and medial one-third of the tibial tuberosity for the tibia. Angle between these two lines was analysed as the rotational mismatch between the components when they were determined based on the anatomical landmark of each bone. Thirty-eight knees (45%) showed more than 5-degree mismatch and seven knees (8.3%) showed the mismatch more than 10-degree. There was a tendency to put the tibial component in external rotation relative to the femoral component when they were aligned to medial one-third of the tibial tuberosity. The results have indicated that the landmark of each bone was the intrinsic cause of the rotational mismatch between the components. The surgeons performing TKA surgery should aware of this fact and should align the tibial component in a compromised position, if necessary, to have overall satisfactory clinical outcome.