The Bristol Knee Replacement Registry was established in the 1970’s and contains prospectively recorded data on 3024 patients. The present study examines the group of 812 patients for whom complete pre-operative and five year post-operative data is available in order to relate their eventual health status to the pre-operative demographic data and to disease severity. The group comprised 593 women and 219 men who had undergone either Kinematic, Total or Sled unicompartmental knee replacement.

Pre-operatively, the average American Knee Society Score (AKSS) was 89 with the elderly, rheumatoid patients and women having significantly lower scores.

Five years later the average AKSS had risen to 161 with patients of all ages, (including the over 80’s) gaining considerably. However, the rheumatoid patients remained more disabled as did women who had a final AKSS of 157 as opposed to 171 for the men (p< 0.01). In addition, a statistically significant finding was that those with the lowest pre-operative scores also had the lowest 5 year scores - they never catch up.

173 patients underwent bilateral knee replacement at separate times. Their pre-operative AKSS was significantly higher at the time of the second knee replacement (90) than the first (82) p< 0.01.

We conclude that since patients present earlier for their second TKR and those with most disability fail to catch up the procedure should be performed earlier in the natural history of the disease, especially in women.