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Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_9 | Pages 103 - 103
1 May 2017
Kaya A Ömer Ü Oğuz PŞ Bahattin K Samet E Burak Ö
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Background

Osteoarthritis (OA) pain treatment has limitations in terms of serious adverse effects and low efficacy. We aimed to evaluate efficacy and safety of naproxen sodium/codeine phosphate combination in these patients.

Methods

In this prospective, randomised, double blind, placebo controlled clinical trial, 135 patients with osteoarthritis, who were 40–65 years; applied to our institution's orthopaedics outpatient clinic; had grade 1, 2, or 3 primary osteoarthritis diagnosed in last 1 year; and had Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score≥40, and Visual Analogue Scale score≥40, were enrolled. Subjects were randomised (1:1) to placebo (n= 67) or combination (n= 68) arms, in which 550 mg naproxen sodium/30mg codeine phosphate was given orally twice a day for 7 days. Rescue medicine was 500 mg paracetamol (max= 6 tablets/day). Demographic characteristics, medical history, adverse events, VAS and WOMAC scores were collected in study visits performed within 10 days. The study was approved by local institutional ethics committee and written informed consents were obtained from all participants.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 88 - 88
1 May 2011
Guclu B Kaya A Akan B Benli T Cetin I
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Background: the purpose of this paper is to evaluate the functional and clinical results of the developmental high dislocated hips after subtrochanteric transverse shortening osteotomy fixed axially and rotationally by cementless femoral stem and the asetabular component placed into the anatomical place.

Methods: in a retrospective study, we evaluated the results and complications of twenty-four consecutive primary cementless total hip arthroplasty in eighteen patients (sixteen female and two male) all of whom had Crowe IV (Hartofilakidis type III) high dislocations. The arthroplasty was performed in combination with a subtrochanteric transverse shortening osteotomy and Zweymüller femoral stem(SL plus) without any fixation instruments for the osteotomy site and with placement of the acetabular component at the level of anatomic hip center. All of the patients were evaluated at a mean of 4 years postoperatively.

Results: the mean Harris Hip score increased from 17.25 points preoperatively to 84.87 points at the time of final follow up (p< 0.01). Seven of the twenty four hips had an early or late complications and/or reoperations. None of the subtrochanteric osteotomies were followed by non-union and no other complications concerning the femoral site is seen. There was one instance of isolated loosening of asetabuler component. Two hips dislocated postoperatively which were treated by closed reduction and bracing for 12 weeks. One siatic neurapraxic injury was identified which resolved within 6 months’ time. Intraoperative femoral cracks were seen in three hips. One of them on the proximal part (trochanteric site) and the other two on the distal femur. All were fixed by cerclage and cables without any further pain and complications.

Conclusions: subtrochanteric shortening osteotomy and cementless total hip arthoplasty for the treatment of developmental dysplasia and dislocations of the hip were associated with high rates of successful fixation of the femoral component and the asetabulum. The osteotomy site has a healing potential within the eight weeks’ time without any complications. The mean Harris hip score was 84.87 points. The complication rate is higher than that associated with primary total hip arthroplasty for the degenerative arthritis.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 100 - 100
1 May 2011
Tuncay I Kaya A Demirörs H Akgün R Kaya U Kuru I
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Introduction: One of the most frequently seen complications of structural allograft recontructions are either delayed or nonunion. The effect of the periosteum on union of autoclaved segmental bone grafts were investigated in rabbits.

Method: Segmental bone defects, 10 milimeters long, in the middle of the left radius were created in 16 adult rabbits. The resected bones, autoclaved 15 minutes at 120 C and reimplanted and fixed with intramedullary Kirchner wires. In group one, 8 rabbits’ graft-host bone junctions were covered with periosteal fiap and in group two, graft-host bone junctions were deperiostized. The plain X-rays were taken at 2, 4, 6 and 8 weeks. The rabbits were sacrificed at the end of 8 weeks. Specimens were also examined histologically.

Results: Both radiological and histological results were evaluated. In group one, the results revealed more callus and healing than group two, and they were found statistically significant.

Discussion: Periosteal fiaps are easy to perform and enhances the healing of the graft-host junctions. The periosteal fiap technique is effective on the healing of graft-host bone junctions and this technique will worth applying to structural allografts.