This large UK multicentre study evaluates clinical outcomes and identifies factors associated with local complication following PFR for non-oncological conditions. 132 patients across four UK centres underwent PFR from 01/08/2004-28/03/2023 with median follow-up of 1.9 (Q10.5-Q34.2) years. 75 (56.8%) patients were female and the mean age was 74.0 (SD 11.7) years. 103 (78%) patients had Charleston Comorbidity Index ≥3. ASA class was III or IV in 66.6%. Indications were infected revision (39, 29.5%), periprosthetic fracture (36, 27.3%), acute trauma (30, 22.7%), aseptic revision (17, 12.9%), failed trauma (nine, 6.8%) and complex primary arthroplasty (one, 0.8%). The primary outcome was the local complication rate. Secondary outcomes were systemic complications, reoperation and mortality rates. Comparisons were made with t-tests and Chi2 tests to investigate patient and surgical factors associated with local complication. Statistical significance was p<0.05. There were 37(28.0%) local complications. These were 18 (13.6%) dislocations, eight (6.1%) prosthetic joint infections, four (3.0%) haematomas, three (2.3%) superficial infections, one (0.8%) wound dehiscence, one (0.8%) sciatic nerve palsy and one (0.8%) femoral perforation. Dislocation mostly occurred in conventional articulations (12, 9.1%) followed by dual-mobility cups (three, 2.3%), constrained cups (two, 1.5%) and hemiarthroplasty (one, 0.8%). Median time to local complication was 30 (Q14-Q3 133) days. Seven (5.3%) patients developed a systemic complication. Thirty-three (25.0%) patients underwent reoperation. Thirty-day and one-year mortality rates were 3.8% and 12.1%, respectively. Longer surgical waiting times (7.9 \[SD 16.9) versus 2.6 \[SD 4.4\] days, p<0.001) and longer operating times (212.5 \[SD 71.8\] versus 189.4 \[SD 59.3\] mins, p=0.0450) were associated with local complication. Due to its high complication rate, PFR should be a salvage option when performed for non-oncological indications. Conventional articulations should be avoided. PFR should be delivered in a timely manner and ideally as dual-consultant cases to reduce operating time.
Periprosthetic femoral fracture (PFF) incidence following hip replacement surgery continues to rise. There is a national drive to centralise PFF treatment within specialist centres to improve clinical outcomes and cost-effectiveness. The financial implications of treating PFFs must be analysed to guide allocation of funding. Data were collected for 129 PFFs admitted from 02/04/2014–19/05/2020. Financial data were provided by the Patient Level Information and Costing Systems (PLICS) team. Primary outcomes were cost, revenue and margin for each PFF. Additional data were collected on length of stay (LOS), critical care requirements and clinical outcomes. Statistical comparisons were made between treatment type (fixation vs revision). Significance was set to p<0.05. Across the entire cohort, total cost was £2,389,901, total revenue was £1,695,435 and total loss was £694,481. Highest costs were ward stay (£714,591), theatre utilisation (£382,625), and overheads (£249,110). Median cost was £15,863 (IQR, £11,092-£22,221), median revenue was £11,305 (IQR, £7,147-£15,222) and median loss was £3,795 (IQR, £605-£8687). Median LOS was 21 days (IQR 13–34) and 28.7% patients required critical care admission. Ninety-six patients were treated operatively with either fixation (n=53) or revision (n=43). Median operating time was lower for fixation versus revision (132 [IQR, 115–185] vs 201 [IQR, 159–229] minutes, p=0.001). Median cost (£17,455 [IQR, £13,095-£22,824] vs £17,399 [£13,394-£23,404]) and median loss (£5,774 [IQR, £2,092-£10,472] vs £3,860 [IQR, £96-£7,601]) were similar for fixation and revision (p=0.99 and p=0.18, respectively). Median revenue was greater for revision versus fixation (£13,925 [IQR, £11,294-£17,037] vs £12,160 [IQR, £8,486-£14,390], p=0.02). There was no difference in LOS (21 [13–34] vs 21 [14–30] days, p=0.94), critical care requirements (20 [37.7%] vs 11 [25.6%], p=0.30), reoperations (3 [5.7%] vs 6 [14.0%], p=0.29], local complications (8 [15.1%) vs 12 [27.9%], p=0.20) or systemic complications (11 [20.8%] vs 11 [25.6%], p=0.75) between fixation and revision. PFF treatment costs are high with inadequate reimbursement through tariff. Work is needed to address this disparity and reduce costs associated with LOS, theatre utilisation and implants. Treatment cost should not be used when deciding between fixation and revision surgery.
Cemented total hip replacement (THR) provides excellent outcomes and is cost-effective. Polished taper-slip (PTS) stems demonstrate successful results and have overtaken traditional composite-beam (CB) stems. Recent reports indicate they are associated with a higher risk of postoperative periprosthetic femoral fracture (PFF) compared to CB stems. This study evaluates risk factors influencing fracture characteristics around PTS and CB cemented stems. Data were collected for 584 PFF patients admitted to eight UK centres from 25/05/2006-01/03/2020. Radiographs were assessed for Unified Classification System (UCS) grade and Arbeitsgemeinschaft für Osteosynthesefragen/Orthopaedic Trauma Association (AO/OTA) type. Statistical comparisons investigated relationships by age, gender, and stem fixation philosophy (PTS versus CB). The effect of multiple variables was estimated using multinomial logistic regression to estimate odds ratios (OR) with 95% confidence intervals (CI). Median (IQR) age was 79.1 (72.0–86.0) years, 312 (53.6%) patients were female, and 495 (85.1%) stems were PTS. The commonest UCS grade was type B1 (278, 47.6%). The commonest AO/OTA type was spiral (352, 60.3%). Metaphyseal-split fractures occurred only with PTS stems with an incidence of 10.1%. Male gender was associated with a five-fold reduction in odds of a type C fracture (OR 0.22, 95% CI 0.12 to 0.41, p<0.001) compared to a type B fracture. CB stems were associated with significantly increased odds of transverse fracture (OR 9.51, 95% CI 3.72 to 24.34, p <0.001) and wedge fracture (OR 3.72, 95% CI 1.16 to 11.95, p <0.05) compared to PTS stems. This is the largest study investigating PFF characteristics around cemented stems. The commonest fracture types are B1 and spiral fractures. PTS stems are exclusively associated with metaphyseal-split fractures, but their incidence is low. Males have lower odds of UCS grade C fractures compared to females. CB stems had higher odds of bending type fractures (transverse and wedge) compared to PTS stems. Biomechanical testing is needed for validation and investigation of modifiable factors which may reduce the risk of unstable fracture patterns requiring complex revision surgery over internal fixation.
This study evaluates risk factors influencing fracture characteristics for postoperative periprosthetic femoral fractures (PFFs) around cemented stems in total hip arthroplasty. Data were collected for PFF patients admitted to eight UK centres between 25 May 2006 and 1 March 2020. Radiographs were assessed for Unified Classification System (UCS) grade and AO/OTA type. Statistical comparisons investigated relationships by age, gender, and stem fixation philosophy (polished taper-slip (PTS) vs composite beam (CB)). The effect of multiple variables was estimated using multinomial logistic regression to estimate odds ratios (ORs) with 95% confidence intervals (CIs). Surgical treatment (revision vs fixation) was compared by UCS grade and AO/OTA type.Aims
Methods
Reverse hybrid total hip replacement (THR) offers significant theoretical benefits but is uncommonly used. Our primary objective was to evaluate implant survival with all cause revision and revision for aseptic loosening of either component as endpoints. Data was collected prospectively on 1, 088 (988 patients) consecutive reverse hybrid THRs. Mean patient age was 69.3 years (range, 21–94) and mean follow-up was 8.2 years (range, 5–11.3). No patients were lost to follow-up. Overall, 194 (17.8%) procedures were performed in patients under 60 years, 666 (61.1%) were performed in female patients and 349 (32.1%) were performed by a trainee. Acetabular components were ultra-high molecular weight polyethylene in 415 (38.1%) hips, highly cross-linked polyethylene in 669 (61.5%) hips and vitamin E stabilised polyethylene in 4 (0.4%) hips. Femoral stems were collared in 757 (69.7%) hips and collarless in 331 (30.3%) hips. Femoral head sizes were 28 mm in 957 (87.9%) hips and 32 mm in 131 (12.1%) hips. Survival analysis was performed using Kaplan Meier methodology. Log rank tests were used to asses differences in survival by age, gender, head size and surgeon grade.Introduction
Patients/Materials & Methods
The MHRA guidelines for metal on metal (MOM) suggest cobalt and chromium levels of more than 7ppb as potential for soft tissue reaction. However, in some patients soft tissue reaction is seen even in the presence of normal serum metal ions levels. A prospective review of all patients who had metal-on-metal hip arthroplasty was done. Patients who had both serum metal ion levels and MARS MRI scan were included in this study.Introduction
Methods
Revision surgery for a failed metal on metal (MoM) hip arthroplasty is often unpredictable and challenging due to associated massive soft tissue and bony lesions. We present the analysis and early outcomes of revision surgery in failed MoM hip arthroplasties at our institution. We have retrospectively analysed the findings and outcomes of revision surgery in 61 failed MoM hip arthroplasties performed between 2009 and 2014. These patients were identified in the special MoM hip surveillance pathway. All these patients underwent clinical assessment and relevant investigations. Intra-operative and histopathological findings were analysed.Background
Methods
A prospective study was done to assess the outcome of MPFL reconstruction for patellar instability using quadriceps graft. MPFL reconstruction was done using superficial strip of quadriceps by an anteromedial incision and attached close to medial epicondyle of femur. There were 15 knees in thirteen patients with a mean age of 23.4 years. All patients had MPFL reconstruction and 5 had tibial tuberosity transfers. With a mean follow-up of 39.4 (12–57) months, the mean pre-op Kujala scores improved from 47.8 to 87.2. The mean Lysholm scores improved from 54.2 to 86.8. None of the patients had patella re-dislocations. MPFL reconstruction with quadriceps graft appears to be effective producing good results in patients with patellar instability.
To analyse the intra-operative variation in mechanical axes of the lower limb at various stages during navigated total knee replacement. A prospective study was performed to analyse the intra-operative variation in the mechanical axes of the lower limb during navigated total knee replacement. All consecutive patients who underwent navigated total knee replacement were included and patients with inadequate data were excluded from the study. The intra-operative initial, trial and the final mechanical hip-knee-ankle axes were recorded from the navigation system. The differences between these axes were calculated and analysed. There were forty patients, of which 24 were females and 16 males with the age ranging from 37-89 (average 68.4) years. The right knee was replaced in 27 and the left knee in 13 patients. The average initial mechanical axes alignment was 0.03° valgus (3° varus to 3° valgus), trial alignment 0.64° varus (3° varus to 1.5° valgus) and final alignment 0.25° varus (4° varus to 4° valgus). Average deviation from initial to trial axes was 0.97°, trial to final axes was 0.74° and initial to final axes was 1.08°. The correlation co-efficient between the initial and the trial axes was 0.25, trial and final axes was 0.43 & initial and final axes was 0.09. This study highlights a significant variation in mechanical axes between the different stages of navigated total knee replacement. The potential sources of intra-operative errors causing these changes could be soft tissue imbalance, variations in implant placement and possible tracker micro motion. Execution of bony cuts in near normal neutral alignment does not guarantee achievement of near normal final alignment. We advocate surgeons to be vigilant to avoid potential malalignment during navigated total knee replacement.
A retrospective review of all patients transferred by helicopter ambulance to the Great Western Hospital over a 20-month period between January 2003 and September 2004 was undertaken to establish the case-mix of patients (trauma and non-trauma) transferred and the outcome of their admission and length of hospital stay. Details of all Helicopter Emergency Ambulance Service (HEAS) transfers to this unit in the study time period were obtained from the three HEAS providers in the area and case notes for all patients (where available) were reviewed.Background
Methods
Our early results with shoulder resurfacing in management of rotator cuff arthropathy are encouraging. This bone conserving surgery may serve as an alternative to major procedures like reverse shoulder arthroplasty in selected group of patients.
In all 35 patients (29 male) underwent surgery for significant fracture displacement with shortening, manual workers and keen sportsmen at the time of injury. The infraclavicular approach was used in 21 patients and 14 patients had direct incision approach. Radiological union was achieved in all patients after an average of 13.26(8–24) weeks. Six patients required plate removal at 6 months following surgery, infraclavicular (2 patients) &
direct approach (4 patients). All patients returned to their original occupation at average 2.55 months. The Oxford Shoulder Score at 3 months after surgery was average 15 (range12–20) and all patients, except one, scored excellent on subjective scoring.
In all cases, chevron bone cuts have been used. The fixation has progressed from K-wires, through single and double lag screws, tension-band wire, to an AO mini T-plate which is the present technique. With the K-wire, or simple screw methods, the failure rates were up to 50%, leading to many revision operations. Bone graft is used; in first 15 cases this was ‘Allomatrix’ but we now use local bone from the distal radius, taken with an AO tap guide used as a trephine. Functional outcomes were assessed using Quick DASH score, and Gartland and Werley score. There was also a radiographic review. The grip and pinch strength were compared with the contralateral side. We also looked at the progression of disease at scaphotrapezial joint after the fusion of TM joint.
In all cases, chevron bone cuts have been used. The fixation has progressed from K-wires, through single and double lag screws, tension-band wire, to an AO mini T-plate which is the present technique. With the K-wire, or simple screw methods, the failure rates were up to 50%, leading to many revision operations. Bone graft is used; in first 15 cases this was ‘Allomatrix’ but we now use local bone from the distal radius, taken with an AO tap guide used as a trephine. Functional outcomes were assessed using Quick DASH score, and Gartland and Werley score. There was also a radiographic review. The grip and pinch strength were compared with the contralateral side. We also looked at the progression of disease at scaphotrapezial joint after the fusion of TM joint.
Outcomes were assessed by overall subjective satisfaction, Visual Analogue Scale (VAS) for pain, functional scores, range of motion and radiographic evaluation.
6 patients (9%) complained of persisting mild to moderate pain and swelling in the joint. 2 patients (3%) were not happy with the level of deformity correction. All the above 8 patients declined to have joint arthrodesed. 2 patients (3%) had deep infection requiring implant removal. 1 patient had osteolysis on the x-rays but remain asymptomatic. Although radiographic deterioration of the implant was demonstrated in a lot of implants, this deterioration did not correlate with patient satisfaction. We conclude that silastic first metatarsophalangeal joint replacement is a proven procedure that not only provides long- term pain relief but also satisfactory range of movement. Therefore it should still be considered as an option in patients with end-stage hallux rigidus.
To analyse the intra-operative variation in mechanical axes of the lower limb at various stages during navigated total knee replacement. A prospective study was performed to analyse the intra-operative variation in the mechanical axes of the lower limb during navigated total knee replacement. All consecutive patients who underwent navigated total knee replacement were included and patients with inadequate data were excluded from the study. The intra-operative initial, trial and the final mechanical hip-knee-ankle axes were recorded from the navigation system. The differences between these axes were calculated and analysed. There were forty patients, of which 24 were females and 16 males with the age ranging from 37–89 (average 68.4) years. The right knee was replaced in 27 and the left knee in 13 patients. The average initial mechanical axes alignment was 0.03° valgus (3° varus to 3° valgus), trial alignment 0.64° varus (3° varus to 1.5° valgus) and final alignment 0.25° varus (4° varus to 4° valgus). Average deviation from initial to trial axes was 0.97°, trial to final axes was 0.74° and initial to final axes was 1.08°. The cor-relation co-efficient between the initial and the trial axes was 0.25, trial and final axes was 0.43 &
initial and final axes was 0.09. This study highlights a significant variation in mechanical axes between the different stages of navigated total knee replacement. The potential sources of intra-operative errors causing these changes could be soft tissue imbalance, variations in implant placement and possible tracker micro motion. Execution of bony cuts in near normal neutral alignment does not guarantee achievement of near normal final alignment. We advocate surgeons to be vigilant to avoid potential malalignment during navigated total knee replacement.
Significant concerns remain in computer navigated surgery regarding potential errors due to inadequate tracker or array fixation, cutting guide block movements, saw blade deviation, variable component seating and standardisation and validity of radiographic measurements of alignment for outcome assessment. There are no studies in the literature comparing computer generated axes at different steps of operation as well as radiographic axes using scanograms to our knowledge. Long leg films involve significant radiation, which can be minimised by the use of scanograms. A prospective study was performed to compare the per-operative and post-operative alignment of the lower limbs after navigated total knee replacements. All consecutive patients who underwent navigated total knee replacement between May 2006 and November 2006 were included in the study. Patients with inadequate data, patients who refused to participate in the study or lost contact, obvious measurement errors and patients having had recent operations were excluded. The intra-operative initial, trial and the final axes were recorded from the navigation system. Post-operatively a CT (Computer Tomogram) scanogram of the lower limbs was performed as per the scanogram protocol. Measurement of the mechanical hip-knee-ankle axis of the lower limb was performed on the computer. Results were analysed using appropriate statistical methods and comparison made between initial, trial, final and scanogram axes with assessment of their correlation coefficients. Twenty-five patients were initially recruited in the study, of which, 15 were available with completed data. There were four males and 11 females with the age ranging from 57–80 (average 70) years. The right knee was replaced in 12 and the left knee in three patients. The average initial alignment was 0.09° valgus (0.5° varus to 1° valgus), trial alignment 0.59° varus (2° varus to 1° valgus), final alignment 0.56° varus (4° varus to 1.5° valgus) and average radiographic alignment was 0.52° varus (3.1° varus to 1.8° valgus) in maximum possible extension. Average deviation from initial to trial alignment was 0.69° varus, trial to final was 0.03° varus and final to radiographic alignment was 0.12° valgus. Correlation co-efficient of 0.62 between the initial and final axes with average difference of 0.72° varus (p= 0.11, unequal variance 2 tailed) demonstrates reasonable reproducibility of the alignment with computer-guided surgery, also confirming the fact that there is some variation between the initial cut angles and final mechanical axes. Correlation co-efficient of 0.92 between final axes and radiographic axes suggests that scanogram is an imaging modality with reasonable accuracy for measuring mechanical limb alignment despite significantly low radiation and relatively low resolution. Potential errors in radiographic measurements due to rotational malposition combined with flexion deformity is highlighted.
This study aimed to A) establish a protocol for measuring periprosthetic bone mineral density (BMD) of the proximal humerus following implant arthroplasty, and B) compare the differences in the periprosthetic BMD values 4–9 years after surface replacement and stemmed arthroplasties of the proximal humerus. The study design was of retrospective independent samples cohorts, of patients who had received a proximal humeral arthroplasty between January 1992 and December 1996 in a tertiary referral shoulder unit of a UK hospital. The exclusion criteria were A) patient unavailable for study, B) patient refusal, C) inadequate information of dependent and independent variables, or D) obvious measurement errors. All available patients underwent DEXA scanning of the proximal humerus using a Lunar DPXL scanner fitted with Orthopaedic Hip software version 1.3. Replicable patient positioning with a special jig was used. On a predetermined format of Gruen equivalent zones and sub-zones, BMD values in gm/cm2 were plotted. Cortical thickness on plain radiographs was recorded for each zone. Femoral neck DEXA scan was performed to obtain a proportionate value of BMD of the proximal humerus, in order to eliminate the effect of confounding variables. Confounding variables accounted for were age, gender, height, weight, activity level, indication for surgery, duration of implantation, dominance, type of arthroplasty (hemi or total) and use of cemented or uncemented stemmed implants. Statistical analysis was performed using Microsoft excel as well as SPSS software. Initially, 58 shoulders in 52 patients were recruited. 6 patients declined to participate for ill health, 6 had moved out of the area and 8 did not attend or reply. Of the remaining 31 shoulders in 25 patients, 2 patients had an obviously erroneous DEXA reading. 29 shoulders in 23 patients were finally analysed, which included 10 male and 19 female shoulders. Average age was 67.5 years and average time since surgery was 6 years 2 months. Indications for surgery were RA in 14, OA in 8 and other reasons in 7. Of 29 shoulders, 20 received a total replacement, 9 a hemiarthroplasty. The inevitable obliquity of the image caused some difficulties in maintaining accuracy and difficulties were observed due to limitation of the software to measure thin cortices and to distinguish between the cement and bone. There was no significant correlation between gross cortical thickness and BMD values, and the average periprosthetic BMD was 0.54 g/cm2. Surface replacement implants were associated with relative preservation of proximal medial cortex and higher BMD values in this region. BMD values were consistently higher at the level of stem tip for the stemmed implants. No such phenomenon was observed for the surface replacement prostheses. Hemiarthroplasty was associated with relatively higher BMD values in the proximal medial cortical region than total arthroplasty.