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Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_7 | Pages 28 - 28
1 Jul 2022
Yapp L Scott C Macdonald D Howie C Simpson H Clement N
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Abstract

INTRODUCTION

This study investigates whether primary knee arthroplasty (KA) restores health-related quality of life (HRQoL) to levels expected in the general population.

METHODOLOGY

This retrospective case-control study utilises two sources: patients undergoing primary KA from a University Teaching hospital; and individual-level data from the Health Survey for England which was used to represent the General Population.

Propensity score matching was used to balance covariates (sex, age and body mass index (BMI)) and facilitate group comparisons. Two matched cohorts with 3029 patients each were obtained for the adjusted analyses (median age 70.3 interquartile range (IQR) 64–77; Female sex 3233 (53.4%); median BMI 29.7 IQR 26.5-33.7). HRQoL was measured using the three-level version of the EuroQol 5-Dimensions’ (EQ-5D-3L) Index and EQ-VAS scores.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_2 | Pages 34 - 34
1 Jan 2019
Sehgal A Burnett R Howie C Simpson H Hamilton D
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Instability accounts for approximately 20% of revision total knee arthroplasty (TKA) operations, however, diagnostic tests remain relatively subjective. The aim of this examination was to evaluate the feasibility of using pressure mat analyses during functional tasks to identify abnormal biomechanics associated with TKA instability.

Five patients (M = 4; age = 69.80±7.05 years; weight = 79.73±20.12 kg) with suspected TKA instability were examined compared to 10 healthy controls (M = 4; age = 44.6±7.52 years; weight = 70.80±14.65). Peak pressure and time parameters were measured during normal gait and two-minute bilateral stance. Side-to-side pressure distribution was calculated over 10-second intervals during the second minute. Mann-Whitney tests compared loading parameters between groups and side-to-side differences in TKA patients (significance level = p<0.05).

Pressure distribution was expressed relative to bodyweight. Notable differences were seen during bilateral stance. Uneven side loading was greater – favouring the non-operated limb – in TKA patients during bilateral stance compared to controls. This was significantly different at 30s (p=0.0336) and 60s (p=0.0336). Gait analyses showed subtle pressure distribution differences in unstable TKA patients. Stance time was indifferent. TKA patients tended to exhibit longer heel contact time (0.76s vs. 0.64s and reduced weight acceptance (50.75% vs. 56.75%) on the operated limb compared to the non-operated limb. Side-to-side differences in peak toe-off forces were significantly more pronounced in TKA patients versus controls (9.25% +/− 1.5% vs. 1.67% +/−5.79%; p=0.0039).

Conclusion: This feasibility work demonstrates subtle differences in limb loading mechanics during simple clinical tests in unstable TKA patients that might be invisible to the naked eye. In the long-term, pressure analyses may be a useful diagnostic tool in identifying patients that would benefit from revision surgery for TKA instability.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_14 | Pages 65 - 65
1 Nov 2018
Sehgal A Burnett R Howie C Simpson H Hamilton D
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Instability accounts for approximately 20% of all revision total knee arthroplasty (TKA), however diagnostic tests remain crude and subjective. The aim of this examination was to evaluate the feasibility of pressure mat (SB Mat, TekScan) analyses of functional tasks to differentiate instability in a clinical setting. Five patients (M = 4; age = 69.80±7.05 years; weight = 79.73±20.12 kg) with suspected TKA instability were examined compared to five healthy controls (M = 1; age = 46.80±7.85 years; weight = 71.54±16.17 kg). Peak pressure and time parameters were measured during normal gait and two-minute bilateral stance. Side-to-side pressure distribution was calculated over 10-second intervals during the second minute. Pressure distributions were expressed relative to bodyweight (%BW). T-tests compared loading parameters between groups (significance level = p<0.05). Analyses showed subtle differences in pressure distribution in unstable TKA patients versus healthy controls. Stance time during gait was indifferent. TKA patients tended to exhibit longer heel contact time (0.76 vs. 0.64 sec) and reduced weight acceptance (50.75% vs. 56.75%) on the operated versus non-operated limb. Side-to-side differences in toe-off forces were significantly more pronounced in TKA patients versus controls (9.25% vs. 3.75%; p=0.0088). Uneven loading was significantly greater – favouring the non-operated limb – in TKA patients during bilateral stance compared to controls (p<0.05). This feasibility work demonstrates subtle differences in limb loading and biomechanics during simple clinical tests in unstable TKA patients that might be undetectable to the naked eye. Pressure analyses may therefore be a useful diagnostic tool. These findings warrant further investigation.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_16 | Pages 130 - 130
1 Nov 2018
Howie C
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Patient reported outcomes have become validated objective measures of success in research studies. They take time and effort to develop and administer. However, to remain relevant and universal PROMS should be gathered routinely and used to manage evidence-based change in healthcare systems. To ensure that they are adopted individual clinician involvement is key however a framework for comparison and relevance promotes engagement. Several examples will be presented of system change using PROMS and PREMS as well as using routine data to defend patient selection. How and what we present depends on whom we are expecting to influence.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_3 | Pages 13 - 13
1 Apr 2018
Giesinger J Loth F McDonald D Giesinger K Patton J Simpson H Howie C Hamilton D
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Aim

To investigate the validity of threshold values for the Oxford Hip and Knee Score (OHS and OKS) for treatment success 12 months after total knee or hip replacement.

Methods

Questionnaires were administered to patients undergoing total hip (THA) or knee (TKA) replacement before and 12 months after surgery alongside questions assessing key accepted aspects of treatment success (satisfaction, pain relief, functional improvement) to form a composite criterion of success and assessed using receiver operator characteristic (ROC) analysis. Thresholds providing maximum sensitivity and specificity for predicting treatment success were determined for the total sample and subgroups defined by pre-surgery scores.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_3 | Pages 2 - 2
1 Apr 2018
Hamilton D Loth F MacDonald D Giesinger K Patton J Simpson H Howie C Giesinger J
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Aim

To evaluate the association of BMI and improvement in patient-reported outcomes after TKA.

Methods

Knee replacement outcome data for procedures carried out over an eight month period was extracted from a regional arthroplasty register in the UK. Data was available before surgery and 12 months after. We analysed the impact of overweight on post-operative change in the Forgotten Joint Score − 12 (FJS-12) measuring joint awareness and the Oxford Knee Score (OKS) measuring pain and function using five BMI categories (A: <25, B: 25–29.9, C: 30–34.9, D: 35–39.9 and E: >40).


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_16 | Pages 43 - 43
1 Oct 2016
Hamilton D Giesinger K Giesinger J Loth F Simpson A Howie C
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Obese patients undergoing total knee arthroplasty (TKA) face increased risks of complications such as joint infection and early revision. However, the influence of obesity on measures of patient function following TKA is poorly defined.

Knee arthroplasty outcome data for procedures carried out over an eight month period was extracted from a regional database in the UK. We analysed the impact of weight categories (BMI<30, BMI=30–34.9, and BMI≥35) on the Forgotten Joint Score – 12 (FJS-12) and Oxford Knee Score (OKS). Data was available preoperatively and 12 months postoperatively. Physical and mental health was assessed with the SF-12 one year after surgery.

Data from 256 patients were available. 49.6% had a BMI<30, 27.4% had a BMI 30–34.9 and 23.1% had a BMI≥35. Mean FJS-12 results at 1-year were 48.7 points for patients with a BMI<30, 40.7 points for patients with a BMI=30–34.9 and 34.0 points for patients with a BMI≥35. Effect sizes for change from baseline to 12-month post-op were 3.0 (Cohen's d) in patients with BMI<30 and d=2.2 in patients with BMI≥35. Mean OKS results at 1 year were 36.9 (BMI<30), 33.7 (BMI=30–34.9) and 32.0 (BMI≥35) respectively. Effect sizes for change from baseline to 12-month was d=2.1 (BMI<30) and d=1.9 (BMI≥35). Differences between BMI groups with regard to post-operative change were statistically significant for the FJS-12 (p=0.038) but not for the OKS (p=0.229).

This study highlights that outcome scores may differ in their ability to capture the impact of obesity on patient function following TKA. The FJS-12 showed significant differences in outcome based on patient obesity category, whereas the OKS did not detect between group differences.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_16 | Pages 40 - 40
1 Oct 2016
Hamilton D Simpson P Patton J Howie C Burnett R
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Patient function is poorly characterised following revision TKA. Modern semi-constrained implants are suggested to offer high levels of function, however, data is lacking to justify this claim.

52 consecutive aseptic revision TKA procedures performed at a single centre were prospectively evaluated; all were revision of a primary implant to a Triathlon total stabiliser prosthesis. Patients were assessed pre-operatively and at 6, 26, 52 and 104 weeks post-op. Outcome assessments were the Oxford Knee Score (OKS), range of motion, pain rating scale and timed functional assessment battery. Analysis was by repeated measures ANOVA with post-hoc Tukey HSD 95% simultaneous confidence intervals as pairwise comparison. Secondary analysis compared the results of this revision cohort to previously reported primary TKA data, performed by the same surgeons, with identical outcome assessments at equivalent time points.

Mean age was 73.23 (SD 10.41) years, 57% were male. Mean time since index surgery was 9.03 (SD 5.6) years. 3 patients were lost to follow-up. All outcome parameters improved significantly over time (p <0.001). Post-hoc analysis demonstrated that all outcomes changed between pre-op, 6 week and 26 weeks post-op assessments.

No difference was seen between primary and revision cohorts in OKS (p = 0.2) or pain scores (p=0.19). Range of motion and functional performance was different between groups over the 2 year period (p=0.03), however this was due to differing pre-operative scores, post-hoc analysis showed no difference between groups at any post-operative time point.

Patients undergoing aseptic revision TKA with semi-constrained implants made substantial improvements in OKS, pain scores, knee flexion, and timed functional performance, with the outcomes achieved comparable to those of primary TKA. High levels of function can be achieved following revision knee arthroplasty, which may be important considering the changing need for, and demographics of, revision surgery.


Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_17 | Pages 7 - 7
1 Dec 2015
Clement N MacDonald D Burnett R Simpson A Howie C
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This study assessed whether patient satisfaction with their hospital stay influences the early outcome of total knee replacement (TKR).

During a five year period patients undergoing primary TKR at the study centre had prospectively outcome data recorded (n=2264). Patients with depression (p=0.04) and worse mental wellbeing (p<0.001), according to the short form (SF)-12, were more likely to be dissatisfied with their hospital stay. Decreasing level of satisfaction with their hospital stay was associated with a significantly worse post-operative OKS (p<0.001) and SF-12 score (p<0.001). Multivariable regression analysis confirmed that the patients perceived level of satisfaction with their hospital stay was an independent predictor of change in the OKS (p<0.001) and SF-12 score (p<0.001) after adjusting for confounding variables. Patient satisfaction with their TKR was significantly influenced by their hospital experience, decreasing from 96% in those with an excellent experience to 42% in those with a poor experience. Food, staff/care, and the hospital environment were the most frequent reasons of why patients rated their hospital experience as fair or poor.

A patient's perception of their inpatient hospital experience after surgery is an important modifiable predictor of early functional outcome and satisfaction with TKR.


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_11 | Pages 29 - 29
1 Jul 2014
Hamilton D Lane J Gaston P Patton J MacDonald D Simpson H Howie C
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Summary Statement

Service industry metrics (the net promoter score) are being introduced as a measure of UK healthcare satisfaction. Lower limb arthroplasty, as a ‘service’, scores comparably with the most successful commercial organisations.

Background

Satisfaction with care is important to both the patient and the payer. The Net Promoter Score, widely used in the service industry, has been recently introduced to the UK National Health Service as an overarching metric of patient satisfaction and to monitor performance. This questionnaire asks ‘customers’ if they would recommend a service or products to others. Scores range from −100 (everyone is a detractor) to +100 (everyone is a promoter). In industry, a positive score is well regarded, with those over 50 regarded as excellent. Our aims were to assess net promoter scores for joint arthroplasty, to compare these scores with direct measures of patient satisfaction, and to evaluate which factors contributed to net promoter response.


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_11 | Pages 30 - 30
1 Jul 2014
Hamilton D Clement N Patton J Burnett R Gaston P Howie C Simpson H
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Summary Statement

Using current analysis/methodology, new implant technology is unlikely to demonstrate a large enough change in patient function to impact on the cost-effectiveness of the procedure.

Purpose

Cost effectiveness is an increasingly important metric in today's healthcare environment, and decisions surrounding which arthroplasty prosthesis to implant are not exempt from such health economic concerns. Quality adjusted life years (QALYs) are the typical assessment tool for this type of evaluation. Using this methodology, joint arthroplasty has been shown to be cost effective, however studies directly comparing the QALY achieved by differing prostheses are lacking.


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_3 | Pages 2 - 2
1 Feb 2014
Jenkins P Ramaesh R Lane J Knight S MacDonald D Howie C
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Many psychological factors have been associated with function after joint replacement. Personality is a stable pattern of responses to external conditions and stimuli. The aim of this study was to investigate the relationship between personality, joint function, and general physical in patients undergoing total hip (THR) and knee replacement (TKR).

We undertook a prospective cohort study of 184 patients undergoing THA and 205 undergoing TKA. Personality was assesed using the Eysneck Personality Questionaire, brief version (EPQ-BV). Physical health was measured using the EuroQol (EQ-5D). Joint function was measured using the relevant Oxford Score. Outcomes were assessed at six months. Multivariable models were constructed.

The stable introvert personality was most common. Unstable introverts had poorer pre-operative function with hip arthrosis, but not knee arthrosis. Personality was not directly associated with post-operative function – the only independent predictors were pre-operative function (p=0.002) and comorbidity (p<0.001). While satisfaction after TKR was associated with personality (p=0.026), there was no association after THR (p=0.453). The poorest satisfaction was in those with the unstable introvert personality type.

Personality was a predictor of preoperative status. It did not have a direct association with postoperative status, but may have as preoperative function was the main predictor of postoperative function, personality may have had an indirect effect. Personality was also a predictor of satisfaction after TKR. This suggests that predicting satisfaction after knee replacement is more complex. Therefore certain patient may benefit from a tailored preoperative education to explore and manage expectations.


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_3 | Pages 13 - 13
1 Feb 2014
Turnbull G MacDonald D Clement N Howie C
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Expectations of patients requiring knee arthroplasty surgery have become higher than in the past, with more strain being put on modern prostheses by fitter and younger patients. The objective of this study was to analyse the survivorship of primary knee arthroplasties at a minimum of ten years, with end points of revision and death. Patients who had a total (TKA) or unicompartmental (UKA) knee arthroplasty performed at a university teaching hospital were identified from the local arthroplasty database. Electronic and operative records were analysed to determine parameters including operative indication, subsequent revision surgery, and patient mortality. Results were collated and analysed using PASW software.

A total of 1023 patients were recruited, with 566 (55%) female and 457 (45%) male. Minimum follow up was 10.1 years, with an average of 12.1 years (S.D 0.87). 64.9% of patients were alive at follow up, with an average age of 79.7 years (S.D 8.7). 92.8% were operated on for osteoarthritis (OA), 6.6% for rheumatoid arthritis (RA) and 0.6% for other indications. Kaplan–Meier analysis estimated survival of 94% (S.D 0.008) at eleven years, with no statistical difference found in survivorship of knees operated on for OA or RA. Similarly no statistical difference was found between survivorship of UKA or TKA implants. Of those that died by follow up, 95.2% did so with their original implant.

We conclude that both TKA and UKA offer a lasting solution for patients, with excellent outcomes achieved in both rheumatoid and osteoarthritic patients.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_33 | Pages 9 - 9
1 Sep 2013
Whitgift J Howie C Mandziak D Cheng C MacDonald D
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Nerve damage is a complication of THA and TKA procedures. The incidence of subclinical nerve injury following arthroplasty is unknown. The aim was to determine the prevalence of asymptomatic nerve deficits in an arthroplasty population group, and the incidence of post-operative changes in nerve function. A Secondary aim was to identify the nature of any deficits. And the association between nerve deficits and history of backache.

A non-randomised prospective series of patients undergoing lower limb arthroplasty for osteoarthritis were studied at a single hospital. The peroneal nerve was investigated using nerve conduction in forty patients. Twenty patients had upper limb testing to differentiate between a polyneuropathy or isolated lower limb neuropathy.

Nerve function deficits were detected in the peroneal nerve in fifteen patients pre-operatively and fifteen post-operatively, of those twelve had A waves detected suggestive of a generalised neuropathy. Ten patients who had upper limb testing had a conduction defect (five had asymptomatic Carpal tunnel). There was a positive correlation between presence of post-operative deficit and age(r=0.389, p=0.013). A negative correlation was found for presence of post-operative A waves and BMI(r=−0.370, p=0.019).

The prevalence of pre-operative subclinical peroneal neuropathy is much higher than expected in this group (37.5%) of arthroplasty patients. There is a strong correlation between presence of post-operative conduction abnormalities and age. There is no relationship between peripheral neuropathy and history of backache or residual post-operative deficit.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_5 | Pages 8 - 8
1 Feb 2013
Jenkins PJ Clement N Hamilton D Patton J Simpson H Howie C
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The aim was to perform a cost-utility analysis of total joint replacement in the current environment.

Arthritis is a disabling condition that leads to long-term deterioration in quality of life. Total joint replacement, despite being one of the greatest advances in medicine in the modern era, has come under recent scrutiny. The National Health Service (NHS) has competing demands and resource allocation is challenging in times of economic restraint.

Patients undergoing total hip (n=348) and knee arthroplasty (n=323), from January to July 2010, were entered into a prospective arthroplasty database. A health utility score was derived from the Euroqol (EQ-5D) score preoperatively, and at one year, and was combined with individual life expectancy to derive the Quality-Adujusted-Life-Years (QALYs) gained. Predicted need for revision surgery was Incorporated in the model. The 2011–12 Scottish Tariff was used. Two-way analysis of variance was used to compare QALYs gained between procedures, while controlling for baseline differences.

The number of QALYs gained was higher in THR versus TKR (6.53 vs 4.04 years, p<0.001). The cost per QALY for THR was £1371 (95% CI £1194 to £1614) compared with £2101 (£1762 to £2620) for TKR. Predictors of an increase in QALYs gained were poorer health prior to surgery (p<0.001) and younger age (p<0.001). General health (EQ-5D VAS) showed greater improvement in THR versus TKR (p<0.001).

This study provides up to date cost-effectiveness data for total joint replacement. THR and TKR are both extremely clinically and cost-effective interventions, with costs that compare favourably with other medical interventions (e.g. laparoscopic hernia repair vs open: £55,548 per QALY; CHD primary prevention with statins: £21,000).


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 72 - 72
1 Jan 2013
Hamilton D Gaston P Patton S Burnett R Howie C Simpson H
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Introduction

Many prosthetic design changes have been introduced in attempt to improve outcomes following TKA; however there is no consensus as to whether these changes confer benefits to patients. This study aimed to assess whether patients treated with a modern implant design had an enhanced patient outcome compared to a traditional model in a double blind randomised controlled trial.

Methods

212 consecutive patients were prospectively randomised to receive either a modern (Triathlon) or a traditional (Kinemax) TKA (both Stryker Orthopaedics). 6 surgeons at a single unit performed all procedures in a standardised manner. A single researcher, blinded to implant allocation, performed all assessments. Patients were assessed pre-operatively, and at 6, 26, 52 weeks post-surgery with the Oxford Knee Score (OKS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, goniometry, timed functional assessment, lower limb power (Leg Extensor Power Rig) and pain numerical rating scales (NRS). Change in scores and between group differences were assessed with Two-Way Repeated Measures ANOVAs.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 203 - 203
1 Jan 2013
Bugler K Scott C Clement N Macdonald D Howie C Biant L
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Patient expectations and their fulfilment are an important factor in determining patient-reported outcome and satisfaction of hip (THR) and knee replacement (TKR). The aim of this prospective cohort study was to examine the expectations of patients undergoing THR and TKR, and to identify differences in expectations, predictors of high expectations and the relationship between the fulfilment of expectations and patient-reported outcome measures. During the study period, patients who underwent 346 THRs and 323 TKRs completed an expectation questionnaire, Oxford score and Short-Form 12 (SF-12) score pre-operatively. At one year post-operatively, the Oxford score, SF-12, patient satisfaction and expectation fulfilment were assessed. Univariable and multivariable analysis were performed. Improvements in mobility and daytime pain were the most important expectations in both groups. Expectation level did not differ between THR and TKR. Poor Oxford score, younger age and male gender significantly predicted high pre-operative expectations (p < 0.001). The level of pre-operative expectation was not significantly associated with the fulfilment of expectations or outcome. THR better met the expectations identified as important by patients. TKR failed to meet expectations of kneeling, squatting and stair climbing. High fulfilment of expectation in both THR and TKR was significantly predicted by young age, greater improvements in Oxford score and high pre-operative mental health scores. The fulfilment of expectations was highly correlated with satisfaction.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 168 - 168
1 Jan 2013
Jenkins P Ramaesh R Howie C Goffin J Patton J Pankaj P Simpson H
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Introduction

Osteoarthritis continues to be a major cause of pain and disability. The pathological processes leading to the end-stage of joint degeneration remain poorly understood. Advances in radiological imaging have the potential to improve understanding of the structural and functional changes observed in OA. The aim of this study was to describe the microarchitecture of the femoral head in osteoarthritis.

Methods

Twenty osteoarthritic femoral heads underwent micro-computed tomography scanning at 30µm. Four parameters of micro-architecture and structure were determined: bone volume ratio (BV:TV), trabecular thickness, structural model index and degree of anisotropy. The femoral head was divided into 27 cubic volumes of interest. Analysis of variance (ANOVA) was used to assess differences between regions. Cystic and sclerotic changes were assessed qualitatively.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_V | Pages 1 - 1
1 Mar 2012
Clement N MacDonald D Howie C Biant L
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There is limited literature regarding the outcome of hip and knee arthroplasty (THR and TKR) in the Super-Elderly (≥80yrs). The aim is to compare the outcome of THR and TKR in the Super-Elderly with a standard-age cohort of patients. From January 2006 to August 2008; 1290 TKR and 1344 THR were performed at the study institute. Comorbidity, length of stay, patient satisfaction, Oxford knee or hip scores, and SF12 scores were recorded prospectively. The Oxford Score and SF12 were recorded at one year. The mode age range was 65-74yrs for TKR (n=492) and THR (n=495), deemed the standard cohort. 185 TKR and 171 THR were performed in the Super-Elderly. Outcome in this cohort was compared to the standard.

The standard cohort had a greater absolute improvement in Oxford knee scores (15.8 and 14.7.p=0.2). Improvement of absolute Oxford hip scores revealed no difference (20.0 and 20.2.p=0.8), but the Super-Elderly had a greater improvement in pain components (11.0 vs.12.0.p=0.05) with a lesser improvement of the functional components (9.0.vs.8.2.p=0.05). There was a greater improvement in the physical component of the SF-12 score in the standard cohort for both TKR and THR (10.6.vs.7.9.p=0.05 and 14.4.vs.10.4.p=<0.01, respectively).

No significant difference was seen in comorbidities, but the Super-Elderly patients had a longer hospital stay for TKR (6.2.vs.8.3.p=0.01) and THR (5.9.vs.9.0.p=0.01).

The Super-Elderly were more satisfied with their surgery (p=0.05).

Super-Elderly patients have comparable outcomes to their younger counterparts and are more satisfied with their surgery, but they may require a longer length of stay.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 12 - 12
1 Feb 2012
Clayton R Watts A Gaston P Howie C
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Aim

To investigate the incidence, types and trends in diagnosis of venous thromboembolic events (VTE) in patients undergoing total knee arthroplasty (TKA) over a ten-year period.

Methods

Data from 5100 consecutive TKAs performed in our unit between April 1996 and March 2006 were prospectively collected by the Scottish Arthroplasty Project (SAP). This database contains data on 100% of arthroplasty cases in Scotland. We retrospectively reviewed casenotes of these patients to identify thromboprophylaxis given, the diagnosis of VTE, treatment and adverse outcomes.