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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 67 - 67
1 Jul 2012
Highcock AJ Craghill EJ Simmons DJ
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INTRODUCTION

We examined whether the introduction of an oral factor Xa inhibitor, increased total blood loss in patients undergoing primary total knee arthroplasty surgery.

METHODS

Two groups were studied. The intervention group were prescribed a factor Xa inhibitor 6-10 hours post-surgery, and the control group were prescribed low molecular weight heparin (LMWH) 6-10 hours post-surgery. All other factors were kept constant.

Pre- and post-operative haemoglobin levels (post-operative on day 2) were recorded. Any requirement for transfusion was also documented. Actual drop in haemoglobin levels was compared between the two groups.