Purpose of the study: This was a retrospective analysis of patients with bone loss subsequent to an open leg fracture. Negative pressure therapy was applied in 42 cases over a period of 47 months.

Material and method: Our strategy was designed around the goal of secondary rather than emergency cover, after preparation of the wound bed with NPWT. The time from the first surgical care to NPWT was 23.38 days on average. Mean duration of NPWT was 21.19 days.

Results: After NPWT, gain in wound surface was 18.09% on average. The gain was nil for 52.38% of the patients, positive for 47.62% and exceptional for 4.76%. 100% of the wounds analysed developed a regular border which prepared a bed for a graft or flap without decreasing the depth of the wound. NPWT enabled all patients to reach the set objective: directed healing in 19%, skin graft in 48%, flap in 33%. The objective were achieved for 66% of patients, exceeded, partially achieved for 14% and not reached for 10%.

Discussion: We conclude that NPWT is an excellent way to wait for slow healing after cleaning. It stimulates formation of a granulation tissue, favours the development of regular borders, and cleans the wound before definitive surgical treatment. Thus whether achieved with a flap, a graft or directed healing, the final cover is thus minimised. NPWT can also reduce the risk of infection during the initial phase since the wound is drained and outside contamination is limited by the air-tight dressing. Cost remains a limitation even though certain studies have found equivalent cost with conventional dressings, often related to use of lower cost “homemade” dressings.

Purpose: We report the clinical and radiological outcome observed with Charnley total hip arthroplasties in a series of patients aged less than 60 years followed for at least 25 years.

Material and methods: This retrospective analysis included 141 consecutive total hip arthroplasties performed between 1972 and 1975 with a Charnley implant. The same surgeon used the same technique for all implants. All of these patients had been followed regularly for at least 25 years. We recorded radiographic measures of polyethylene cup wear and its impact on prosthesis life. We tested the influence of different factors on the development of femoral or acetabular loosening. Survival curves were calculated for acetabular and femoral components.

Results: At last follow-up 28 prostheses were still in place, 44 had undergone revision, 42 were lost to follow-up and 27 patients had died. At last follow-up, including the revised hips, joint function was considered, good, very good or excellent in 86% of the cases (merle d’Aubigné score 15 – 18 points). Polyethylene wear was 0.12 mm/year. Merkel osteolysis was observed in 50% of the cases.

Discussion and conclusion: This work demonstrates the good functional outcome provided by Charnley total hip arthroplasty. The wear and loosening rates were higher than observed in older patients. Prognosis depends on polyethylene wear and its biological consequences.

Purpose: The purpose of this experimental study was to compare fixation with hooks and screws inserted posteriorly. A digitalized analysis using finite element analysis was applied.

Material and methods: We used seven human thoracic spines for this experimental study. We identified 49 pairs of two vertebrae. Traction was applied to rupture, the maximal force at rupture measured with an Instron. Fixations were made with four pedicle screws and two pediculolaminar clamps. For the digitalized study, the modellised vertebra was composed of 63000 nodes and 14000 elements. Calculations were made in the elastic domain using the finite elements abacus method.

Results: Traction on the peidculolaminar clamp produced a fracture at the base of the pedicles in all cases. When screw fixation was used, there was a medial fissuration of the base of the pedicle. For hooks, pull-out force was 1108±510 Newtons. It was 820±418 Newtons for the 4-mm diameter screws and 1395±425 Newtons for the 5-mm screws. T5–T6 and T7–T8 assemblies ruptured more easily. The screw model demonstrated a concentration of the stress forces at the medial level of the pedicle, inside the spinal canal. Use of a long screw did not reduce stress significantly. The hook model demonstrated maximal stress force at the lower level of the pedicles.

Discussion and conclusion: From a mechanical point of view, screw fixation is best, but this type of fixation did not fulfil all expectations. The results showed that the force for 4-mm screws is 23% weaker than for hooks and that 5-mm screws only provide a 12% better force than hooks. There are two mechanisms for pull-out, stripping of the bone threads, or rupture of the pedicles. The bone thread strips when the screw threads do not penetrate the cortical bone sufficiently because the screw is too small. On the contrary, larger screws risk injuring the pedicle. Pedicle rupture is observed for much higher stress force and constitutes the upper limit of resistance. This leads us to hypothesise that in most cases, screw pull-out occurs by bone thread stripping. Screws are less effective if they cannot be correctly anchored in the cortical, probably the cause of their relative weakness. The screw diameter should be chosen to adapt to the diameter of each pedicle. Stress forces would be transmitted better from the screw to the pedicle. The vertebrae are exposed to greater stress forces with hooks. The digitalised study confirmed that use of long screws crossing the entire vertebra did not provide a sufficient diminution of stress on the pedicles to justify their use.