Background

Lateral Unicompartmental Knee Arthroplasty (UKA) is a recognised treatment option in the management of lateral Osteoarthritis (OA) of the knee. Whilst there is extensive evidence on the indications and contraindcations in Medial UKA there is limited evidence on this topic in Lateral UKA. The aim of this study was to assess our experience of mobile lateral UKR and to look specifically at the effect of Contraindications on the outcome.

Introduction

The commonest causes of revision of Unicompartmental Knee Replacement (UKR) in National Registers are loosening and pain. Cementless UKR was introduced to address loosening and was found, in small randomised studies, to have better radiographic fixation than Cemented UKR. Although non-significant these studies also suggested the clinical outcome was better with cementless. The aim of this larger study was to compare the pain and function of cementless and cemented UKR at five years.

Introduction

Unicompartmental knee replacement (UKR) offers advantages over total knee replacement but has higher revision rates particularly for aseptic loosening. Cementless UKR was introduced in an attempt to address this. We used National Joint Registry (NJR) data to compare the 10-year results of cemented and cementless mobile bearing UKR whilst matching for important patient, implant and surgical factors. We also explored the influence of caseload on outcome.

Introduction

The revision rate of unicompartmental knee replacement (UKR) in national joint registries is much higher than that of total knee replacements and that of UKR in cohort studies from multiple high-volume centres. The reasons for this are unclear but may be due to incorrect patient selection, inadequate surgical technique, and inappropriate indications for revision. Meniscal bearing UKR has well defined evidence based indications based on preoperative radiographs, the surgical technique can be assessed from post-operative radiographs and the reason for revision from pre-revision radiographs. However, for an accurate assessment aligned radiographs are required. The aim of the study was to determine why the revision rate of UKR in registries is so high by undertaking a radiographic review of revised UKR identified by the United Kingdom's (UK) National Joint Registry (NJR).

Objectives

The primary stability of the cementless Oxford Unicompartmental Knee Replacement (OUKR) relies on interference fit (or press fit). Insufficient interference may cause implant loosening, whilst excessive interference could cause bone damage and fracture.

The aim of this study was to identify the optimal interference fit by measuring the force required to seat the tibial component of the cementless OUKR (push-in force) and the force required to remove the component (pull-out force).

Aims

An evidence-based radiographic Decision Aid for meniscal-bearing unicompartmental knee arthroplasty (UKA) has been developed and this study investigates its performance at an independent centre.

There is a large amount of evidence available about the relative merits of unicompartmental and total knee arthroplasty (UKA and TKA). Based on the same evidence, different people draw different conclusions and as a result, there is great variability in the usage of UKA.

The revision rate of UKA is much higher than TKA and so some surgeons conclude that UKA should not be performed. Other surgeons believe that the main reason for the high revision rate is that UKA is easy to revise and, therefore, the threshold for revision is low. They also believe that UKA has many advantages over TKA such as a faster recovery, lower morbidity and mortality and better function. They therefore conclude that UKA should be undertaken whenever appropriate.

The solution to this argument is to minimise the revision rate of UKA, thereby addressing the main disadvantage of UKA. The evidence suggests that this will be achieved if surgeons use UKA for at least 20% of their knee arthroplasties and use implants that are appropriate for these broad indications.

Cite this article: Bone Joint J 2015;97-B(10 Suppl A):3–8.

The cementless Oxford unicompartmental knee replacement has been demonstrated to have superior fixation on radiographs and a similar early complication rate compared with the cemented version. However, a small number of cases have come to our attention where, after an apparently successful procedure, the tibial component subsides into a valgus position with an increased posterior slope, before becoming well-fixed. We present the clinical and radiological findings of these six patients and describe their natural history and the likely causes. Two underwent revision in the early post-operative period, and in four the implant stabilised and became well-fixed radiologically with a good functional outcome.

This situation appears to be avoidable by minor modifications to the operative technique, and it appears that it can be treated conservatively in most patients.

Cite this article: Bone Joint J 2014;96-B:345–9.

STUDY PURPOSES

To evaluate the role of “top up” intra-articular local anaesthetic injection in patients who have had UKR.

INTRODUCTION

Mobile bearing unicompartmental knee replacement (UKR) is an accepted treatment for patients with isolated medial unicompartmental knee osteoarthritis (OA) with a full thickness cartilage loss. The aim of this study was to determine if this recommendation was correct and if the procedure could be used for partial-thickness cartilage loss.

Introduction: Patellofemoral joint subluxation is associated with pain and dysfunction. The causes of patel-lofemoral subluxation are poorly understood and multi-factorial, arising from abnormalities of both bone and soft tissues. This study aims to identify which anatomical variables assessed on Magnetic Resonance (MR) images are most relevant to patellofemoral subluxation.

Method: A retrospective analysis of MR studies of 60 patients with suspected patellofemoral subluxation was performed. All patients were graded for the severity/ magnitude of radiological subluxation using a dynamic MR scan (Grade 0 [nil] to Grade 3 [subluxed]. The patient scans were assessed using a range of anatomical variables, these included:

Patella alta,

Results: The distance of the VMO from the patella (p < 0.001), TTD (p < 0.001) and Patella Engagement (p < 0.001) showed highly significant relationships with patellofemoral subluxation.

Conclusions: The following three anatomical variables are associated with patellofemoral subluxation: the distance of the VMO muscle from the patella, TTD and Patella Engagement.

This is the first study to establish that patella engagement is related to PFJ subluxation showing that the lower the percentage engagement of the patella in the trochlea, the greater the severity/magnitude of patellofemoral subluxation. The finding provides greater insight into the aetiology and understanding of the mechanism of symptomatic PFJ subluxation.

Purpose: To evaluate the effects of underhanging/overhanging tibial components on clinical outcome following the Oxford unicompartmental knee arthroplasty (UKA), and to identify an acceptable sizing limit.

Method: One hundred and sixty-three knees which had undergone the Phase 3 medial Oxford UKA (Biomet, Swindon) were measured. Based on five-year post-operative radiographs, they were divided into groups with tibial component underhang (n=38), none or minimal overhang of less than three millimetres (n=121), and a group with overhang equal to or in excess of three millimetres (n=13). Clinical outcome was assessed by changes in the twelve-question Oxford Knee Score (ΔOKS) and pain score (ΔPS) component (questions 1,4,5,8,9) from pre-operative assessment to five years following surgery.

Results: At five years after surgery, ΔOKS was significantly worse in the overhang group compared to both the neutral and underhang groups (p=0.015, and p=0.028 respectively). ΔPS was also shown to be significantly worse between the overhang and the neutral group (p=0.026 respectively).

Conclusion: Appropriate sizing of the tibial component is essential to optimise load bearing in total knee arthroplasty. In UKA such sizing is critical due to halving of the bony support for the tibial component and the lack of room for a large stem. Excessive undersizing of the prosthesis may lead to subsidence and loosening, whilst excessive overhanging may cause local soft tissue irritation and pain.

This study demonstrates that medial overhang of less than three millimetres for the tibial component is acceptable in the Oxford UKA. Excessive overhang equal to this or more results in significantly worse ΔOKS and ΔPS. However, no difference in the five year ΔOKS and ΔPS was demonstrated between underhang and the other two groups in this study.

Purpose: Varus deformity after total knee replacement (TKR) is associated with poor outcome. This aim of this study was to determine whether the same is true for medial unicompartmental arthroplasty (UKA).

Methods: 158 patients implanted with the Oxford UKA, using a minimally invasive approach, were studied prospectively for five years. Leg alignment was measured with a long-arm goniometer referenced from Anterior Superior Iliac Spine, centre of patella and centre of ankle. Patients were grouped according to the American Knee Society Score (AKSS). Group A: > 0° varus (n=13, 8.2%); Group B: 0 to 4° valgus (n=39, 24.7%); Group C: 5–10° valgus (normal alignment, n=106, 67.12%). Comparisons were made between the three groups in terms of the absolute and the change in Oxford Knee Score (OKS) and AKSS over the five year period, and the presence of radiolucency.

Results: There was no significant difference in any outcome measure except for Objective-AKSS (p< 0.001). The means and standard deviations of the ΔOKS for the groups were:

24 ± 5,

The frequency of five year radiolucency for the groups A, B, and C were 42%, 35%, and 45% respectively.

Conclusion: The aim of the Oxford UKA is to restore knee kinematics and thus knee alignment to the pre-disease state. Therefore, as demonstrated by this study, about 30% of patients have varus alignment. This study also demonstrates that post-operative varus alignment does not compromise the outcome. The only score which did show worse outcome was the Objective-AKSS. This is because 10 or 20 points are deducted for varus alignment, which is not appropriate following UKA. Therefore, AKSS in its present form is not a reliable tool for assessment of UKA.

Purpose: To identify associative factors for radiolucency (RL) under the tibial component following the Oxford unicompartmental arthroplasty (UKA), and to evaluate its effect on clinical outcome scores.

Method: One hundred and sixty-one knees which had undergone primary Phase 3 medial Oxford UKA were included. Fluoroscopic radiography films were assessed at five years post-operatively for areas of tibial RL. The two groups of patients, with and without RL, were compared to

patients’ pre-operative demographics for age, weight, height, BMI,

Results: 101 (62%) knees were found to have tibial RL. All RL were categorised as physiological or they were < 1mm thick, with sclerotic margins and non-progressive. No statistical difference was found between knees with RL and those without, in terms of pre-operative demographics, intra- or post-operative factors, and clinical outcome scores (p> 0.1 in all variables).

Discussion: Radiolucency (RL) under the tibial component is a common finding following the Oxford UKA. Many theories have been proposed to explain the cause of RL, such as poor cementing, osteonecrosis, micromotion, and thermal necrosis. However, the true aetiology and clinical significance remain unclear. We attempted to address this.

We found no significant relationship between physiological RL, pre-operative demographics, intra-operative variables and clinical outcome scores in this study. Tibial RL remains a common finding following the Oxford UKA yet we do not know why it occurs but in the medium term, clinical outcome is not influenced by RL. In particular, it is not a sign of loosening. Physiological RL can therefore be ignored even if associated with adverse symptoms following the Oxford UKA.

Introduction: This study assesses the outcome of medial unicompartmental knee arthroplasty (UKA) using the Oxford prosthesis for end-stage focal spontaneous osteonecrosis of the knee (SONK, Ahlback grades III & IV).

Methods: A total of 29 knees (27 patients) with SONK were assessed using the Oxford Knee Score. Twenty-six had osteonecrosis of the medial femoral condyle; 3 had osteonecrosis of the medial tibial plateau. This group was compared to a similar group who had undergone Oxford Medial UKA for primary osteoarthritis. Patients were matched for age, sex and time since operation.

Results: Mean length of follow-up was 5.2 years (range 1–13 years). There were no implant failures in either group, but there was one death 9 months post-arthroplasty from unrelated causes in the group with osteonecrosis. The mean Oxford Knee Score in the group with osteonecrosis was 37.8 (± 7.6) and 40.0 (± 6.6) in the group with osteoarthritis. There was no significant difference between the two groups using Student’s t-test (p=0.31).

Interpretation: Use of the Oxford Medial UKA for focal spontaneous osteonecrosis of the knee is reliable in the short to medium term, and gives similar results to when used for patients with primary osteoarthritis.

Introduction This study assesses the outcome of medial unicompartmental knee arthroplasty (UKA) using the Oxford prosthesis for end-stage focal spontaneous osteonecrosis of the knee (SONK, Ahlback grades III & IV).

Methods A total of 29 knees (27 patients) with SONK were assessed using the Oxford Knee Score. Twenty-six had osteonecrosis of the medial femoral condyle; 3 had osteonecrosis of the medial tibial plateau. This group was compared to a similar group who had undergone Oxford Medial UKA for primary osteoarthritis. Patients were matched for age, sex and time since operation.

Results Mean length of follow-up was 5.2 years (range 1–13 years). There were no implant failures in either group, but there was one death 9 months post-arthroplasty from unrelated causes in the group with osteonecrosis. The mean Oxford Knee Score (SD) in the group with osteonecrosis was 37.8 (7.6) and 40.0 (6.6) in the group with osteoarthritis. There was no significant difference between the two groups using Student’s t-test (p=0.29).

Interpretation Use of the Oxford Medial UKA for focal spontaneous osteonecrosis of the knee is reliable in the short to medium term, and gives similar results to when used for patients with primary osteoarthritis.

Introduction: A new procedure has been recently adopted to implant the Oxford medial unicompartmental arthroplasty (UCA). All cases are now implanted through a short incision without dislocation of the patella. The aims of this study were to assess the one-year results using this new technique and to determine if the outcome is dependent on surgical experience.

Method: The first 104 Oxford UCA’s (Phase 3) implanted by six surgeons under the care of two consultants were reviewed at one year. All operations were performed using the new technique. The average age at surgery was 68 years. All knees were scored pre-operatively and at review with the American Knee Society score. The cohort was divided into two groups; the first ten cases for each surgeon were included in a ‘learning’ group, whilst the remaining cases were included in an ‘experienced’ group.

Results: Overall the average ‘knee score’ improved from 37 points to 94 and the average ‘functional score’ from 50 points to 92. Average maximum flexion improved from 117° to 131°. The ‘knee score’ for the ‘learning’ group was 91 points. This was significantly less (p = 0.008) than the score of the ‘experienced’ group (96 points).

Conclusions: These results are significantly better than the best historical results of the Oxford (UCA), performed through an open approach with dislocation of the patella.

Despite impressive overall results at one year, lower knee scores were associated with a surgeons ‘learning curve’. After this ‘learning curve’, increased surgical experience led to further improvement with 90% achieving an excellent result, 8% a good, 2% a fair and 0% a poor result.

Introduction: In conjunction with a bilateral randomised control trial comparing the clinical outcome of two total knee arthroplasties (TKA), we carried out an in-vivo fluoroscopic analysis of both knees in the trial. Knee A, is a new mobile bearing posterior cruciate retaining TKA and Knee B, an established fixed bearing posterior cruciate retaining TKA.

Method: In an ethically approved study, video fluoroscopy was taken of both knees of seven patients performing three exercises; extension against gravity, flexion against gravity and a step up exercise. Ten images at ten-degree intervals over the flexion range were frame grabbed and digitised. The relationship of patella tendon angle (PTA) to knee flexion angle (KFA) was assessed using a newly developed computer system. Five normal knees in fit volunteers were also fluoroscoped and assessed.

Results: A similar pattern of results was obtai ed for all three exercises. Knee A behaved in a linear, more consistent fashion than Knee B, which behaved non-linearly. Analysis of variance showed this difference was significant for all three exercises (p < 0.039).

Conclusions: This bilateral study provides a powerful way of assessing the kinematics of two different knee implants. Knee A behaves in a linear predictable fashion that is nearer normal than Knee B. These results will be used in conjunction with a clinical outcome study and an RSA study to provide a complete assessment of a new TKA.

Introduction: The Oxford medial unicompartmental arthroplasty (UCA) is now routinely performed through a short incision without Dislocation of the patella. The aim of this study was to assess the one-year results of this new technique to determine whether it enhances the quality of outcome, as well as the speed of its achievement.

Method: The first 88 consecutive Oxford UCA’s (Phase 3) implanted into 75 patients by two consultant surgeons were scored pre-operatively and at review with the American Knee Society Score. The average age of the patients was 68.1 years; the male to female ratio was 0.9 to 1.

Results: At review, one patient (one knee) had died and one knee had been revised for infection. The other patients (86 knees) were examined at a mean of 1.3 years from surgery. The average ‘knee score’ improved from 37 points to 95 and the average ‘functional score’ from 51 points to 93. Average maximum flexion improved from 117° to 132°. The ‘knee score’ outcome categories at review were 87% excellent, 8% good, 2.5% fair and 2.5% poor.

Conclusions: Historical comparison of these results with the best results of the Oxford UCA, performed through an open approach with dislocation of the patella, suggest that the minimally invasive approach, in addition to faster recovery, improves the quality of outcome at one year.

A randomised controlled trial was performed to compare the clinical outcome for the two commonest types of anterior cruciate ligament (ACL) reconstruction. Methods: Patients undergoing elective anterior cruciate reconstruction were randomised into one of two groups. Group PT underwent reconstruction using a patella tendon autograft (n=14), whereas Group SG had a semitendinosus/gracilis autograft (n=18). The same surgeon performed all operations. IKDC self reported function and activity scores were recorded pre-operatively and at one and five years post operation. KT1000 values and muscle strength were recorded pre-operatively and one year post operation.

Results: No significant difference between groups was found for any measurement at one year despite adequate study power. At five year follow up patients in the PT group had superior scores in every category of the IKDC self reported function score (mean IKDC score for PT group = 83, mean IKDC score for SG = 75). The activities of squatting and kneeling revealed the greatest difference between groups. It was found that 71% of patients in the PT group achieved IKDC scores of 80 or over whereas only 61% of patients in the SG group achieved 1 KDC scores of 80 or over.

Conclusion: The study indicates that both techniques produce acceptable outcome for anterior cruciate ligament reconstruction but use of the patella tendon autograft may provide slightly more favourable results, especially for activities involving squatting and kneeling.