Thirty-six patients with anterior cruciate ligament (ACL) insufficiency and varus malalignment were treated with combined ACL reconstruction and medial opening wedge high tibial osteotomy (HTO). Average follow-up was twenty-five months. All patients had improved ligamentous stability and twenty-five patients returned to full activities. Osteotomy union rate was 100%, mechanical axis angle was corrected from six degrees varus to neutral and the mechanical axis deviation was corrected from 2cm medial to 1cm lateral. We experienced four complications, including one deep infection. Combining ACL reconstruction and HTO simultaneously accomplishes a ligamentously stable knee with corrected alignment, allowing patients to return to activity. To determine clinical outcome after combined ACL reconstruction and medial opening wedge high tibial osteotomy (HTO). ACL reconstruction with medial opening HTO can be a beneficial procedure in properly selected patients presenting with complaints of both pain and instability. Correction of varus mal-alignment may provide protection for articular cartilage and improve joint stability. Concomitant medial opening HTO performed at time of ACL reconstruction allows patients to return to activities after one procedure with a ligamentously stable knee, corrected alignment, and potential protection of articular cartilage. Thirty-six patients who underwent ACL reconstruction along with medial opening HTO were retrospectively evaluated postoperatively at an average of twenty-five months. Average age was thirty-seven years at time of surgery. All patients were recreationally active. Pre-operatively all patients had knee pain and instability, varus angulation, and twenty-two patients had previous knee surgery. Semitendinosus/gracilis grafts were used in all patients, and osteotomies were fixed with Puddu plates. Postoperatively patients had improved ligmentous stability with radiographic and clinical evidence of osteotomy healing, and all but nine patients have returned to full activities. We experienced four complications: one ACL failure, one case of anterior laxity with tibial tunnel widening, and two infections. On average, MAD was corrected from 22mm medial to 10mm lateral; mechanical axis angle was corrected from 6.4 degrees of varus to 0.2 degrees of valgus; tibial slope was increased from 9.1 degrees to 10.3 degrees, and patellar height ratio was decreased from 0.9 to 0.8.