Vancomycin is a commonly used antibiotic for prophylaxis in total joint replacement surgery. Several studies have reported superior local tissue concentration of vancomycin using intraosseous (IO) infusion compared with standard intravenous (IV) administration in total knee arthroplasty (TKA). We reviewed patients undergoing primary TKA who received IO vancomycin to a group receiving IV vancomycin. A retrospective review of 1038 patient who underwent primary TKA at our institution was performed from May 1, 2016 to May 1, 2019. This was a consecutive series of patients before and after we adopted this technique. IO vancomycin administration technique has been previously reported from our institution (500mg vancomycin in 200mL solution). Comparisons included preoperative and postoperative creatinine values, adverse reaction to vancomycin, tourniquet time, re-operation rates, periprosthetic joint infection rate at 1 year.Introduction
Methods
Patient-specific design (PSD) total knee arthroplasty (TKA) implants are marketed to restore neutral mechanical axis alignment (MAA) and provide better anatomic fit compared to standard off-the-shelf (OTS) TKA designs. The purpose of this study was to compare the Knee-Society scores, radiographic outcomes, and complications of PSD and OTS implants. IRB approved prospective study comparing PSD and OTS by a single surgeon. Implant design change in PSD occurred during the study leading to PSD-1 and PSD-2 subgroups. Demographic, radiographic data including MAA, coronal-tibial angle (CTA), femoro-tibial angle (FTA), tibial-slope (TS) and patella-tilt (PT), and complications were analyzed. Minimum follow-up was 2 year or until revision, and patients completed Knee-Society scores preoperatively, and postoperatively at 3-, 6-, 12-, 24 weeks and final follow up.Background/Purpose
Methods
