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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_7 | Pages 68 - 68
4 Apr 2023
Kelly E Gibson-Watt T Elcock K Boyd M Paxton J
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The COVID-19 pandemic necessitated a pivot to online learning for many traditional, hands-on subjects such as anatomy. This, coupled with the increase in online education programmes, and the reduction of time students spend in anatomy dissection rooms, has highlighted a real need for innovative and accessible learning tools. This study describes the development of a novel 3-dimensional (3D), interactive anatomy teaching tool using structured light scanning (SLS) technology. This technique allows the 3D shape and texture of an object to be captured and displayed online, where it can be viewed and manipulated in real-time.

Human bones of the upper limb, vertebrae and whole skulls were digitised using SLS using Einscan Pro2X/H scanners. The resulting meshes were then post-processed to add the captured textures and to remove any extraneous information. The final models were uploaded into Sketchfab where they were orientated, lit and annotated. To gather opinion on these models as effective teaching tools, surveys were completed by anatomy students (n=35) and anatomy educators (n=8). Data was collected using a Likert scale response, as well as free text answers to gather qualitative information.

3D scans of the scapula, humerus, radius, ulna, vertebrae and skull were successfully produced by SLS. Interactive models were produced via scan data in Sketchfab and successfully annotated to provide labelled 3D models for examination. 94% of survey respondents agreed that the interactive models were easy to use (n=35, 31% agree and 63% strongly agree) and 97% agreed that the 3D interactive models were more useful than 2D images for learning bony anatomy (n=35; 26% agree and 71% strongly agree).

This initial study has demonstrated a suitable proof-of-concept for SLS technology as a useful technique for producing 3D interactive online tools for learning and teaching bony anatomy. Current studies are focussed on determining the SLS accuracy and the ability of SLS to capture soft tissue/joints. We believe that this tool will be a useful technique for generating online 3D interactive models to study orthopaedic anatomy.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_13 | Pages 52 - 52
1 Dec 2022
Moskven E Lasry O Singh S Flexman A Fisher C Street J Boyd M Ailon T Dvorak M Kwon B Paquette S Dea N Charest-Morin R
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En bloc resection for primary bone tumours and isolated metastasis are complex surgeries associated with a high rate of adverse events (AEs). The primary objective of this study was to explore the relationship between frailty/sarcopenia and major perioperative AEs following en bloc resection for primary bone tumours or isolated metastases of the spine. Secondary objectives were to report the prevalence and distribution of frailty and sarcopenia, and determine the relationship between these factors and length of stay (LOS), unplanned reoperation, and 1-year postoperative mortality in this population.

This is a retrospective study of prospectively collected data from a single quaternary care referral center consisting of patients undergoing an elective en bloc resection for a primary bone tumour or an isolated spinal metastasis between January 1st, 2009 and February 28th, 2020. Frailty was calculated with the modified frailty index (mFI) and spine tumour frailty index (STFI). Sarcopenia, determined by the total psoas area (TPA) vertebral body (VB) ratio (TPA/VB), was measured at L3 and L4. Regression analysis produced ORs, IRRs, and HRs that quantified the association between frailty/sarcopenia and major perioperative AEs, LOS, unplanned reoperation and 1-year postoperative mortality.

One hundred twelve patients met the inclusion criteria. Using the mFI, five patients (5%) were frail (mFI ³ 0.21), while the STFI identified 21 patients (19%) as frail (STFI ³ 2). The mean CT ratios were 1.45 (SD 0.05) and 1.81 (SD 0.06) at L3 and L4 respectively. Unadjusted analysis demonstrated that sarcopenia and frailty were not significant predictors of major perioperative AEs, LOS or unplanned reoperation. Sarcopenia defined by the CT L3 TPA/VB and CT L4 TPA/VB ratios significantly predicted 1-year mortality (HR of 0.32 per one unit increase, 95% CI 0.11-0.93, p=0.04 vs. HR of 0.28 per one unit increase, 95% CI 0.11-0.69, p=0.01) following unadjusted analysis. Frailty defined by an STFI score ≥ 2 predicted 1-year postoperative mortality (OR of 2.10, 95% CI 1.02-4.30, p=0.04).

The mFI was not predictive of any clinical outcome in patients undergoing en bloc resection for primary bone tumours or isolated metastases of the spine. Sarcopenia defined by the CT L3 TPA/VB and L4 TPA/VB and frailty assessed with the STFI predicted 1-year postoperative mortality on univariate analysis but not major perioperative AEs, LOS or reoperation. Further investigation with a larger cohort is needed to identify the optimal measure for assessing frailty and sarcopenia in this spine population.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_32 | Pages 12 - 12
1 Sep 2013
Matthews AH Bott AR Boyd M Metcalfe JE
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We present a complete audit cycle of Emergency Department management of paediatric clavicle fractures at Derriford Hospital.

Local guidelines divide the clavicle into three zones. Fractures with minimal displacement in the middle 3/5th heal in the majority of cases without complication and can be discharged without need for follow up, provided parents are adequately educated.

An initial audit cycle of 63 cases identified short comings in adherence to the guidelines. These included: Unnecessary fracture clinic follow up of ‘Zone 2’ fractures in 85% and omission of written advice in 86%.

The results were circulated, ‘aide memoir’ icons were added to the department's computer coding system, staff teaching sessions were organised and a patient advice sheet was produced.

Following the implementation of changes, a 23 case re-audit showed fewer unnecessary referrals to fracture clinic (17% vs. 85%) and improvements in the number of parents being given written advice (43% vs. 14%).

Staff training, provision of information leaflets and changes to the ED coding system dramatically improved the adherence to hospital guidance.

This resulted in standardisation of care, fewer unnecessary appointments and cost savings to the trust. Following this audit, a telephone survey was completed to assess parent's satisfaction with their treatment.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_18 | Pages 1 - 1
1 Apr 2013
Boyd M Adams S Williams M
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Plymouth Hospitals NHS Trust developed a pelvic and acetabular service in 2008, with the aim to provide a tertiary service for Devon and East Cornwall.

We describe the demographics of the patients, referral and fracture patterns, the operative management undertaken and complications seen in a newly developed tertiary pelvic and acetabular service in the South West.

Over 150 patients have been referred and treated, with follow up in a specialised tertiary clinic. Clinical scoring and radiological follow up were performed, and complications recorded.

Several difficulties and problems were encountered in the development of the service including training issues, equipment availability, surgeon availability, referral pathways and theatre time.

The presentation will describe the clinical results of the service, along with the logistical obstacles encountered in setting up a new service.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLII | Pages 11 - 11
1 Sep 2012
Boyd M Middleton S Guyver P Brinsden M
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Military patients have high functional requirements of the upper limb and may have lower pre-operative PROM scores than civilian patients i.e. their function is high when benchmarked, but still insufficient to perform their military role thereby mandating surgery.

Our aim was to compare the pre-operative Oxford Shoulder Instability Scores in military and civilian patients undergoing shoulder stabilisation surgery.

We undertook a prospective, blinded cohort-controlled study (OCEBM Level 3b). The null hypothesis was that there was no difference in the Oxford Shoulder Instability Scores between military and civilian groups. A power calculation showed that 40 patients were required in each group to give 95% power with 5% significance. A clinical database (iParrot, ByResults Ltd., Oxford, UK) was interrogated for consecutive patients undergoing shoulder stabilisation surgery at a single centre. The senior author - blinded to the outcome score - matched patients according to age, gender and diagnosis. Statistical analysis showed the data to be normally distributed so a paired samples t-test was used to compare the two groups.

110 patients were required to provide a matched cohort of 80 patients. There were 70 males and 10 females. Age at the time of surgery was 16–19 yrs (n=6); 20–24yrs (n=28); 25–29 (n=16); 30–34 (n=12); 35–39 (n=12); 40–44 (n=6). 72 patients (90%) had polar group one and 8 patients (10%) had polar group two instability. The mean Oxford Shoulder Instability Score in the civilian group was 17 and the in military group was 18. There was no statistical difference between the two groups (p=0.395).

This study supports the use the Oxford Shoulder Instability Score to assess military patients with shoulder instability.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLII | Pages 12 - 12
1 Sep 2012
Boyd M Middleton S Brinsden M
Full Access

Skills simulation is increasingly used as a training tool in postgraduate surgical training. Trainee's perception of the value of this experience has not previously been investigated.

Our aim was to investigate the value of surgical simulation training delivered by an arthroscopy skills course.

We constructed a subject-specific, self-assessment questionnaire based around the ISCP Peer Assessment Tool. The questionnaire was administered to candidates before and after attending the Plymouth Arthroscopy Skills Course. Participant demographic data was recorded. Questionnaire data was interrogated to give an overview of the course, as well as the benefit of site-specific skills stations. Statistical analysis showed the data to be normally distributed. The paired T-test was used to compare mean values.

Twelve surgical trainees attended the course – CT2 trainees (n=4); ST3 trainees (n=7); ST4 trainee (n=1). 11 candidates completed both administered questionnaires giving a 92% response rate. The global mean score at the beginning of the course was 2.39. The global mean score at the end of the course was 3.90. The mean improvement was 1.51 (p<0.01; 95% CI = 0.96–2.07). Skill station specific scores all showed improvement with the greatest effect in wrist arthroscopy.

CT trainees had a lower mean score compared to ST trainees. Both groups completed the course with similar mean scores.

This study shows that arthroscopy simulation improves trainee-reported ratings of surgical skill. It also shows that less experienced candidates derived the greatest benefit from the training. Further research is required to compare self-assessed performance against objective benchmarks using validated assessment tools.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXII | Pages 4 - 4
1 Jul 2012
Boyd M Anderson T Middleton S Brinsden M
Full Access

Skills simulation is increasingly used as a training tool in postgraduate surgical training. Trainee's perception of the value of this experience has not previously been investigated. The aim of this investigation was to investigate the value of surgical simulation training delivered by an arthroscopy skills course.

We constructed a subject-specific, self-assessment questionnaire based around the ISCP Peer Assessment Tool. The questionnaire was administered to candidates before and after attending the Plymouth Arthroscopy Skills Course. Participant demographic data was recorded. Questionnaire data was interrogated to give an overview of the course, as well as the benefit of site-specific skills stations. Statistical analysis showed the data to be normally distributed. The paired T-test was used to compare mean values.

Twelve surgical trainees attended the course – CT2 trainees (n=4); ST3 trainees (n=7); ST4 trainee (n=1). 11 candidates completed both administered questionnaires giving a 92% response rate. The global mean score at the beginning of the course was 2.39. The global mean score at the end of the course was 3.90. The mean improvement was 1.51 (p<0.01; 95% CI= 0.96-2.07). Skill station specific scores all showed improvement with the greatest effect in wrist arthroscopy. CT trainees had a lower mean score compared to ST trainees. Both groups completed the course with similar mean scores.

This study shows that arthroscopy simulation improves trainee-reported ratings of surgical skill. It also shows that less experienced candidates derived the greatest benefit from the training. Further research is required to compare self-assessed performance against objective benchmarks using validated assessment tools.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXII | Pages 20 - 20
1 Jul 2012
Middleton S Guyver P Boyd M Anderson T Brinsden M
Full Access

Military patients have high functional requirements of the upper limb and may have lower pre-operative PROM scores than civilian patients i.e. their function is high when benchmarked, but still insufficient to perform their military role thereby mandating surgery. Our aim was to compare the pre-operative Oxford Shoulder Instability Scores in military and civilian patients undergoing shoulder stabilisation surgery.

We undertook a prospective, blinded cohort-controlled study (OCEBM Level 3b). The null hypothesis was that there was no difference in the Oxford Shoulder Instability Scores between military and civilian groups. A power calculation showed that 40 patients were required in each group to give 95% power with 5% significance. A clinical database (iParrot, ByResults Ltd., Oxford, UK) was interrogated for consecutive patients undergoing shoulder stabilisation surgery at a single centre. The senior author - blinded to the outcome score - matched patients according to age, gender and diagnosis. Statistical analysis showed the data to be normally distributed so a paired samples t-test was used to compare the two groups. 110 patients were required to provide a matched cohort of 80 patients.

There were 70 males and 10 females. Age at the time of surgery was 16-19yrs (n=6); 20-24yrs (n=28); 25-29 (n=16); 30-34(n=12); 35-49(n=12); 40-44(n=6). 72 patients (90%) had polar group one and 8 patients (10%) had polar group two instability. The mean Oxford Shoulder Instability Score in the civilian group was 17 and the in military group was 18. There was no statistical difference between the two groups (p=0.395).

This study supports the use the Oxford Shoulder Instability Score to assess military patients with shoulder instability.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 585 - 585
1 Nov 2011
Street J DiPaola C Saravanja D Boriani L Boyd M Kwon B Paquette S Dvorak M Fisher C
Full Access

Purpose: There is very little evidence to guide treatment of patients with spinal surgical site infection (SSI) who require irrigation and debridement (I& D) with respect to need for single or multiple I& D’s. The purpose of this study is to build a predictive model which stratifies patients with spinal SSI to determine which patients will go on to need single versus multiple I& D.

Method: A consecutive series of 128 patients from a tertiary spine center (collected from 1999–2005) who required I& D for spinal SSI, were studied based on data from a prospectively collected outcomes database. Over 30 variables were identified by extensive literature review as possible risk factors for SSI, and tested as possible predictors of risk for multiple I& D. Logistic regression was conducted to assess each variable’s predictability by a “bootstrap” statistical method. Logistic regression was applied using outcome of I& D – single or multiple as the “response”.

Results: 24/128 patients required multiple I& D. Primary spine diagnosis was approximately represented by ¼ trauma, ¼ deformity, ¼ degenerative and ¼ oncology/inflammatory/other. Six predictors: spine location, medical comorbidities, microbiology of the SSI, presence of distant site infection (ie. UTI or bacteremia), presence of instrumentation and bone graft type, proved to be the most reliable predictors of need for multiple I& D. Internal validation of the predictive model yielded area under the curve (AUC) of .84

Conclusion: Infection factors played an important role in need for multiple I& D. Patients with +MRSA culture or those with distant site infection such as bacteremia with or without UTI or pneumonia, were strong predictors of need for multiple I& D. Presence of instrumentation, location of surgery in the posterior lumbar spine and use of non-autograft bone predicted multiple I& D. Diabetes also proved to be the most significant medical comorbidity for multiple I& D.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 282 - 282
1 Jul 2011
Street J Lenehan B Boyd M Dvorak M Kwon BK Paquette S Fisher CG
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Purpose: To evaluate the demographics, presentation, treatment and outcomes of spinal infection in a population of Intravenous Drug Users.

Method: Data on all patients with pyogenic spinal infection presenting to a quaternary referral center was obtained from a prospectively maintain database.

Results: Over the five-year study period, there were 102 patients treated for Primary Pyogenic Infection of the Spine of which 51 were Intravenous Drug Users (IVDU). Of this IVDU group there were 34 males. Mean age was 43 years (range 25 – 57). Twenty-three had HIV, 43 Hepatitis C and 13 Hepatitis B. All were using cocaine, 26 were also using Heroin and 44 more than three recreational drugs. Thirty patients presented with axial pain with a mean duration of 51 days (range 3–120). Thirty-one were ASIA D or worse with eight ASIA A. Mean Motor Score of patients with deficit was 58.6. Most common ASIA Motor Levels were C4 and C5. Mean duration of neurological symptoms was seven days (range 1–60). Blood parameters on admission were in keeping with sepsis in immunocompromised patients. None had previous surgery for spinal infection. Twenty-sex were receiving IV antibiotics for known spinal infection. 44 patients were treated surgically. 32 had infection of the cervical spine, 9 Thoracic and 3 Lumbar. 22 had a posterior approach alone, 13 had anterior only while 9 required combined. Mean operative time was 263 mins (range 62 – 742). 13 required tracheostomy. 7 required early revision for hardware failure and 2 for surgical wound infection. Mean duration of antibiotic treatment was 49 days (range 28–116). 26 patients had single agent therapy. 17 had MSSA and 17 MRSA. At discharge 28 patients had neurological improvement (mean 20 ASIA points, range 1–55), 11 had deterioration (mean 13, range 1–50) and 5 were unchanged. There were no in-hospital deaths. At 2 years after index admission 13 patients were dead and none were attending the unit for follow-up.

Conclusion: Primary pyogenic spinal infection in IVDU’s typically presents with sepsis and acute cervical quadriplegia. Surgical management must be prompt and aggressive with significant neurological improvement expected in the majority of patients.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 283 - 283
1 Jul 2011
Lenehan B Street J Zhang H Noonan V Boyd M Fisher C Kwon BK Paquette S Wing PC Dvorak M
Full Access

Purpose: Prospective Observational Population Study to describe the incidence, demographics and pattern of spinal cord injury in British Columbia, Canada, for 10 years to 2004.

Method: Systematic analysis of prospectively collected spine registry data (Vertebase) at Vancouver General Hospital, B.C., Canada from 1995–2004.

Results: During the 10-year study period the 938 patients were admitted with a traumatic spinal cord injury. The Annual Population-Standardized Incidences ranged from 19.94 to 27.27 per million, with a median incidence of 23.34/million and with no significant change over the study period. The mean age was 39.7 years (34.73 in 1995 and 42.1 in 2004, p< 0.05) with a range of 16–92 years. 79.74 % were males. 48.2% of patients were AISA A on admission, of which 48% were quadraparetic. The most common levels of spinal cord injury were C5 (17.3%), C6 (10%), T1 (9.4%), T12 (5.8%). The Mean ASIA score was 50.22 with a range from 0–100. 19.8% of patients had a GCS£13. The mean ISS was 26.02, range of 0 – 75. Motor vehicle collisions and falls were responsible for 59% and 30% of admissions respectively. Mean length of in-hospital stay was 34 days, ranging from 1 – 275 days. In hospital mortality rate was 2.9%. ASIA Grade, Total Motor Score and anatomical level of injury all correlated directly with Length of stay (p< 0.0001).

Conclusion: Acute Traumatic Spinal Cord Injury remains a major cause of significant morbidity among young males. The incidence appears to be increasing in the elderly. Modern multidisciplinary care has greatly reduced the associated acute mortality. Despite multiple prevention strategies the Annual Population-Standardized Incidence remained unchanged over the study period.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 273 - 273
1 Jul 2011
Saravanja DD Fisher CG Dvorak M Boyd M Clarkson P
Full Access

Purpose: Oncologic management of primary bone tumors of the spine is inconsistent, controversial and open to individual interpretation. Tumor margin violation intraoperatively increases local recurrence and mortality. The purpose of this study is to determine whether applying Enneking’s principles to the surgical management of primary bone tumors of the spine significantly decreases local recurrence and/or mortality.

Method: A prospective and retrospective multicenter Cohort Study: Inclusion of patients undergoing en bloc or intralesional resection of primary tumors of the spine at four separate quaternary care centers, between January 1994 and January 2008. Patients were staged, using the Enneking system, prior to surgery and baseline demographic and surgical variables were recorded. Outcomes measured were disease local recurrence, or death. The results were statistically analyzed for significance.

Results: One hundred-fifty patients with primary tumors of the spine were recruited. Average age was 47.0 (range 8 to 83). Sixty-two patients were identified to have local recurrence. A statistically significant decrease in local recurrence (p=0.0001) was observed in favor of en bloc resection. In patients with local recurrence there was a significant increased risk of mortality, (p< 0.0001). There was a trend to decreased mortality in the en bloc resection group, not statistically significant (p=0.64).

Conclusion: Wide resection of primary tumors of spine with reconstruction is the standard of care. Application of Enneking’s principles to the spine when managing primary bone tumors significantly reduces local recurrence of the disease process, without an adverse outcome on mortality, and with acceptable HRQOL. Further cohort studies based on stringent data collection prospectively will provide a basis for more detailed study of individual tumor types.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 129 - 129
1 Mar 2008
Bishop P Wing P Boyd M Fisher C Dvorak M
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Purpose: The clinical sequelae associated with acute sciatica have been traditionally attributed to mechanical compression of the spinal nerve root by a herniated disc (HD). More recent studies have demonstrated that the HD induces the release of inflammatory mediators and that a tumor necrosis factor alpha-inhibiting agent can resolve the symptoms.|Selective nerve root block (SNRB) involves the transforaminal application of steroid under fluoroscopic guidance adjacent to the selected nerve root. Well-defined criteria for patients that will most likely benefit from SNRB remain unclear. The goal of this study was to determine whether or not the morphology (i.e. posterolateral, sequestrated, foraminal, far lateral) of HD influences the therapeutic value of SNRB treatment.

Methods: An observational cohort study of 37 patients with acute sciatica of less than 12 weeks duration, McCulloch scores of 4 or 5 and evidence of HD on MRI scan at the appropriate level was completed. Disc morphology was determined by blinded interpretation of the MRI scans by a Musculoskeletal Radiologist. Outcome measures included the Modified Roland-Morris Disability Questionnaire (RDQ), administered on the day of, and 6 weeks following, the SNRB procedure and the Visual Analogue Scale (VAS) filled out by the patient immediately before, 30 minutes after and 6 weeks after SNRB.

Results: Of the 37 patients enrolled in this study, the HD morphology was classified as: posterolateral 20, sequestrated 9, foraminal 6, far lateral 2. 35 of 37 patients (95%) reported a 30 minute VAS score of less than 3/10. 14 of 20 patients (70%) with posterolateral HD reported > 3 point improvement in RDQ and > 5 point improvement in VAS at 6 weeks post procedure. 1 of 9 patients (11%) with sequestrated HD showed the same level of improvement in RDQ and VAS scores. None of the patients with foraminal or far lateral HD reported > 1 point improvement in RDQ or > 2 point improvement in VAS scores.

Conclusions: Patients with posterolateral HD were found to have significantly more favorable outcomes from SNRB than those with sequestrated, foraminal or far lateral HD morphology.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 341 - 341
1 May 2006
Keynan O Fisher C Dvorak M Boyd M
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Introduction: There is clear evidence that violating the margins of a sarcoma or other malignancy during surgical resection will risk local recurrence and diminish overall survival. Previous publications have retrospectively demonstrated this oncologically sound approach to spine tumor management to be internally valid. The external validity or limited generalizability has not been assessed.

Methods: A prospective cohort study design. Included were all patients who underwent enbloc surgical resection of a primary tumor of the spine between January 1994 and November 2003, at the authors’ institution. Tumors were classified using the Ennking and WBB staging systems. All specimens were submitted to a single experienced musculoskeletal pathologist. Surgery was performed by the authors. Surgical approach, specimen margins, complications, adjuvant therapy, neurological status, local recurrence and survival were prospectively collected.

Results: Twenty-six patients (12 males and 14 females) were eligible for the study. Average age was 42 (range 16 to 70). There were 19 malignant tumors and 7 benign. Review by the pathologist revealed that 13 resections were wide, 5 marginal (at dura) and 7 intralesional (2 planned wide, 1 planned marginal). Except in benign lesions intral-esional or marginal margins occurred at dura.

There are 20 surviving patients with an average follow up of 41.5 months (range 6 to 111 months), 15 of who had malignant tumors. None of these patients have evidence of local recurrence and one has evidence of systemic disease.

The health related quality of life, using the SF-36, shows acceptable morbidity of these procedures (PCS=37.73 ± 11.52, MCS=51.69 ± 9.54).

Conclusions: Principles of wide surgical resection, commonly applied in appendicular oncology, can and should be used for the treatment of primary bone tumors of the spine with anticipated acceptable morbidity and satisfactory survival.