Aims

The timing of when to remove a circular frame is crucial; early removal results in refracture or deformity, while late removal increases the patient morbidity and delay in return to work. This study was designed to assess the effectiveness of a staged reloading protocol. We report the incidence of mechanical failure following both single-stage and two stage reloading protocols and analyze the associated risk factors.

Dynamization of fracture fixation is used clinically to improve the bone healing process. This study evaluated the effect of late dynamization on callus stiffness and size in a rat diaphyseal femoral osteotomy. The external unilateral fixator was dynamized by removal of the inner fixator bar, at three weeks (D3-group: n=8) or four weeks (D4-group: n=9) post-operation. Published data of a five week rigid (R-group: n=8) and flexible fixation group (F-group: n=8) were included for comparison. Preoperative and postoperative movements of the rats were measured using a motion detection system. After 5 weeks the rats were sacrificed and healing was evaluated by biomechanical and densitometric methods. By 34 days post-operation, rats from the four fixation groups had similar activity levels. There was no significant difference in flexural rigidity, callus volume or callus mineral density between the D3 and D4-groups. Both the D3-group and D4-group had significantly greater flexural rigidity (p< 0.01) and significantly lower callus total volume (p< 0.03) and callus bone volume (p< 0.03) compared to the F-group. There was no significant difference in flexural rigidity or callus mineral density between the dynamized groups compared to the R-group. However, the D3-group had less callus bone volume (p=0.06) compared to the R-group. The D4-group had significantly less callus bone volume (p=0.02) and less callus total volume (p=0.05) compared to the R-group. Late dynamization led to a stiffer callus with a smaller callus volume compared to continuously flexible fixation. The late dynamized groups had less callus volume than the continuously rigid group, but the stiffness and calcification and of the callus were similar. The late dynamized groups had undergone resorption processes, indicative of more advanced healing. Late dynamization enhanced fracture healing compared to the continuously rigid or flexible fixation

Introduction. Traditionally, radiological union of fractures treated with an Ilizarov frame is confirmed by a period of dynamization - destabilisation of the frame for a period prior to removal. Reduced clinic availability during the COVID-19 pandemic caused a shift to selective dynamisation in our department, whereby lower risk patients had their frames removed on the same day as destabilisation. This study investigates the effects of this change in practice on outcomes and complication rates. Materials & Methods. Adult patients treated with circular frames between April 2020 and February 2022 were identified from our Ilizarov database. Patients were divided into 2 groups: - “dynamised” if their frame was destabilised for a period to confirm union prior to removal; or “not dynamised” if the decision was taken to remove the frame without a period of dynamisation, other than a short period in the clinic. A retrospective review of clinical notes was conducted to determine outcome. Results. 175 patients were included in the final analysis, 70 in the dynamised and 103 in the not dynamised groups, median follow-up was 33 months. 3 patients in the dynamised group failed dynamisation and had their period of fixation extended, subsequently having their frames removed without complication. Two patients suffered a refracture or non-union after frame removal in the dynamised group and none in the not dynamised group, this difference was not statistically significant. Conclusions. In our practice, selective frame removal without a period of dynamisation appears safe. This has the potential to shorten frame time and reduce the number of clinic appointments and radiographic investigations for these patients. Some patients find the period of dynamisation uncomfortable and associated with pin site infection, which can be avoided. We plan to continue this practice and collect further data to confirm these findings in a larger dataset

Introduction. Metabolic bone disease encompasses disorders of bone mineralization, abnormal matrix formation or deposition and alteration in osteoblastic and osteoclastic activity. In the paediatric cohort, patients with metabolic bone disease present with pain, fractures and deformities. The aim was to evaluate the use of lateral entry rigid intramedullary nailing in lower limbs in children and adolescents. Materials and Methods. Retrospective review was performed for an 11-year period. Lower limb rigid intramedullary nailing was performed in 27 patients with a total of 63 segments (57 femora, 6 tibiae). Majority of patients had underlying diagnoses of osteogenesis imperfecta or fibrous dysplasia (including McCune Albright disease). Mean age at surgery was 14 years. Indications for surgery included acute fractures, prophylactic stabilisation, previous nonunion and malunion, deformity correction and lengthening via distraction osteogenesis. Results. All fractures healed. Correction of deformity was successfully achieved in all segments. Delayed union occurred in 4 segments in 1 patient and was successfully treated with nail dynamization. Other complications included prominence, cortical penetrance and loosening of locking screws. One patient who had lengthening performed had nonunion and was managed with exchange nailing and adjunctive measures. Conclusions. Rigid intramedullary nailing is very effective in stabilisation and deformity correction of long bones in adolescent patients with pathological bone disease. The technique has low complication rates. We recommend the use of this technique in paediatric units with experience in managing metabolic bone conditions

Introduction: Dynamization is used to improve the healing process. The optimal time for dynamization however remains unknown. In this study we proved the hypothesis that an early dynamization will improve the fracture healing. Material and Methods: Twenty-four rats underwent a diaphyseal femoral osteotomy, with a 1mm gap. The osteotomy was stabilized by either rigid (R-group; n=8) or flexible (F-group; n=8) external fixation. The dynamized group (D-group: n=8) had a rigid fixation for 1 week, and then a flexible fixation for the remaining 4 weeks. The flexible fixation design resulted in an axial stiffness of 10N/mm and the rigid fixation in 74N/mm. After 5 weeks, healing was evaluated by biomechanical, densitometric, and histological methods. Results: The flexural rigidity was 47% higher in the R-group than in the F-group (p< 0.01). Also, the flexural rigidity was 45% higher in the R-group than in the D-group (p< 0.01) (Table 1). Mineralized callus tissue volume was 37% lower in the R-group than the D-group (p=0.002). Conclusion: The hypothesis could not be supported, in that early dynamization did not improve healing compared to rigid or flexible fixation. The rigid fixation had a stiffer callus with smaller callus volume, and more calcified tissue in the whole callus. The rigid fixation had bridging in the gap more often, which explains the increased flexural rigidity measured. Dynamization utilized in previous studies allowed closure of the fracture gap and thereby enhanced the rate of healing, which was not the case in the present investigation

Introduction. Pilon fractures are complex, high-energy, intra-articular fractures of the distal tibia. Achieving good outcomes is challenging due to fracture complexity and extensive soft tissue damage. The purpose of this study was to determine the long-term functional and clinical outcomes of definitive management with fine wire Ilizarov fixation for closed pilon fractures. Materials and Methods. 185 patients treated over a 14-year period (2004–2018) were included. All patients had Ilizarov frames applied to restore mechanical axis and fine wires to control periarticular fragments. CT scans were performed post operatively to confirm satisfactory restoration of the articular surface. All frames were dynamized prior to removal. Patients' functional outcome was assessed using the validated Chertsey Outcome Score for Trauma (“COST”). Review of clinical notes and imaging was used to determine complications and time to union. Results. The mean functional outcome in the studied cohort was determined to be “average” on the “COST” score. Poorer functional outcomes were associated with younger age at time of injury and multi-fragment fracture patterns. Mean time in frame was 170 days. Complication rates were low. There were no deep infections, no amputations and only 8 patients went on to have ankle fusions. Conclusions. Good functional results and low complication rates can be achieved by managing pilon fractures with fine wire Ilizarov fixation. Nonetheless, at time of injury patients should be counselled as to the severity of the injury and impact on their functional status

Femoral nails are thought to be load sharing devices. However, the specific load sharing characteristics and associated stress concentrations have not yet been reported in the literature. The purpose of this study was to use a validated, three dimensional finite element model of a nailed femur subjected to gait loads in order to determine the resulting stresses in the femur and the nail. The results showed that load was shared between the nail and the bone throughout the gait cycle. In addition, high stress concentrations were noted in the bone around the screw holes, and dynamization was of minimal benefit. To determine the stresses in the bone and nail in a femur with a locked, retrograde, intramedullary nail. The retrograde femoral nail is a load sharing device. High stress concentrations occur in the bone around locking screw holes. When only one locking screw is used proximally and distally, stresses in the implant are excessive and may lead to failure. Dynamization was of minimal benefit. This is the first study to use a validated three dimensional finite element model to provide a detailed biomechanical analysis of stress patterns in a retrograde nailed femur under gait loads. The results can help resolve issues of stress shielding, implant removal, number of locking screws and dynamization. In the fully locked condition, loads in the femur were significantly higher than those in the nail for most of the gait cycle. Removal of locking screws to obtain dynamization only increased axial load in the femur by 17 %. However, stresses in the locking screws increased by as much as 250% when fewer than 4 screws were used. Maximum stresses in the bone were found around screw holes. A three dimensional finite element model of the femur and nail was developed. The model was validated by comparing results to a physical saw bone model instrumented with strain gages and subjected to a simple a compressive load. Once good correlation with simple loading patterns was demonstrated, gait loading patterns obtained from literature were incorporated and simulations were run for various conditions

Unstable intertrochanteric fractures may be treated by several types of implants, most frequently by dynamic sliding hip screw or some form of intramedullary implant. Intramedullary implants began to be used in cases with an expectation of further improvement of osteosynthesis stability. A need to determine the advantages of single implants for selected types of fractures in randomized trials was defined. In addition to biomechanical principles, bone quality is considered, together with increasing possibilities in recent years of further improving density measurements, especially qCT with respect to local specificity. A series of 86 patients (24 men, 62 women, average age 77,6 years) was operated on from September 6, 2005 to June 30, 2009 for unstable intertrochanteric fracture (31 A2.1, A2.2, A2.3), either by DHS of PFN osteosynthesis after randomization. A CT examination of both hip joints in a predefined manner was performed before surgery. Using special software the relative density of the central spherical part of the femoral head 2 and 3 centimetres in diameter was determined. After fracture healing, the dynamization of the neck screw of both implants and the reduction of vertical distance between the tip of the neck screw and subchondral bone of the femoral head were determined. In addition to evaluation of osteosynthesis stability and osteosyntheis failure, clinical parameters such as surgical time, blood loss and length of hospital stay were compared between the two groups of patients. Survival of patients was evaluated with respect to April 21, 2010. In the patient series, 4 failures of DHS osteosynthesis (cut out) and 2 failures of PFN osteosynthesis (cut out) were noted. Sliding of the DHS was on average 11,9 mm, and was significantly higher in comparison to dynamization of the PFN neck screw, which was 6,9 mm (p=0,005). When comparing the vertical distance between the tip of the neck screw and subchondral bone of the femoral head immediately after surgery and after fracture healing the average reduction of the vertical distance was 1,6 mm in DHS osteosynthesis and 0,8 mm in PFN osteosynthesis. The difference was statistically significant (p=0,025). PFN seems to provide a more stable fixation, based on the measurements. The number of failed DHS osteosyntheses is higher in comparison to the number of failed PFN osteosyntheses but the difference is not statistically significant. The influence of femoral head density on osteosynthesis failure could not be determined due to a low number of failed osteosyntheses in both patient groups. At the same time, after statistical analysis, influence of the relative femoral head density on vertical distance reduction between the screw tip and femoral head subchondral bone in healed fractures was not proven. Statistically, average length of surgical time, length of hospital stay, mean blood loss and survival did not differ significantly between the two patient groups

Septic complications of long bone fracture are still a significant clinical problem. Although inflammatory process after intramedullary nailing is a rare complication, its treatment is complex. The aim of this study is to analyze the effectiveness of the treatment of septic complications of the long bone union with use of Reamer–Irrigator–Aspirator (RIA) technique and intramedullary antibiotic-coated PMMA nailing. An analysis of the effectiveness of treatment of 49 patients with septic non-union of long bones (12 femur, 37 tibia), in which the RIA method was applied with antibiotic cement impregnated intramedullary nailing. Treatment consisted of reaming of long bone canal using the RIA technique and the intramedullary cement coated nail with the targeted antibiotic. Treatment required second stage with nail exchange and PMMA removal after 6 weeks to prevent the resitant strains selection. In a group of patients treated with use of above-mentioned method the remission of inflammatory process was achieved in all cases. 32 (67%) patients developed bone union, 24 patients with tibial and 8 patients with femoral septic bone union disorders. The average duration of bone union obtainment with intramedullary nailing was 37 weeks. The most common inconveniences that occurred during treatment was prolonged wound discharge and pain. Inflammatory complications of fractures in our material involved extensive injuries, usually high-energetic. Stabilization with intramedullary locked nail coated with antibiotic cement after debridement with RIA method is a convincing treatment. An essential element of biological bone union is to provide a good cover of the bone tissue with a soft tissue envelope and sequestrectomy. The success of the treatment of infected pseudoarthrosis may be obtained under condition of: radical removal of inflammation tissue, convincing biomechanical dynamized stabilization and antibiotic therapy

Aims

This study aimed to demonstrate the promoting effect of elastic fixation on fracture, and further explore its mechanism at the gene and protein expression levels.

Purpose: To evaluate the efficacy of intramedullary nailing for the treatment of the fractures of the proximal quarter of the tibia with special respect on the reduction accuracy. Patients: This is a retrospective study which was conducted in our institution between October 2004 and March 2007. 30 extrarticular proximal tibia fractures were treated with intramedullary nailing. The mean age of the patients was 27 years (19 to 47). Seven fractures (23%) were open – Gustillo grade I-, twelve fractures (12%) had segmental comminution and six (6%) were bifocal fractures. Static intramedullary nailing was chosen in all cases. Distal dynamization was performed routinely in all fractures at an average of 7 weeks (6 to 12 weeks) after the primary operation. Union of the fracture and the accuracy of the reduction were assessed clinically and radiologically. Results: The average follow up was 16 months (9 to 22). All fractures united without additional procedures. Acceptable alignment was obtained in 28 of 30 fractures (93%). Postoperative angulation was satisfactory (average frontal and sagittal plane deformity of less than 2 degrees) in 26 fractures (87%). Two patients had frontal plane deformities (one 4° varus and one valgus 7°) and two patients had a saaggital plane deformities (7° procuvartum). No significant complication was recorded. Conclusions: The proximity of the upper tibia fracture to the knee makes the treatment of these fractures more challenging. Closed intramedullary nailing combined with special reduction technique is a safe and effective method of managing of the proximal tibia fractures

Introduction: Ankle fusion presents a difficult problem in the presence of infection and poor bone stock. Ilizarov method provides stability with remote fixation and allows weight bearing. Patients and Methods: Fourteen consecutive patients were studied. The mean age at onset of disease was 50 years(range 4–70). 13 of the patients had either clinical or radiological evidence of infection prior to ankle fusion surgery. Mean duration of problem was 52 months(range 8–372). Aetiology included traumatic arthritis in 5, failed fusion in 6, septic arthritis in 1, infected ankle fracture nonunion in 1 and avascular necrosis of talus in 1. There were 10 males and 4 females. Local excision was followed by Ilizarov frame compression. Diagnosis of infection was based on microbiology and histology. Antibiotics treatment was continued until union. On radiological evidence of union the frame was dynamized and removed. Below knee cast was applied for 4 weeks. Results: 13 of 14 patients had complete ankle fusion at a mean period of 5 months. 1 patient who had partial fusion of the ankle had recurrence of infection requiring amputation. Complications included pin site infection, lateral impingement, deep infection, hind-foot pain and neuroma at amputation site. Conclusion: The Ilizarov ankle fusion is a reliable salvage procedure in difficult ankle problems

Introduction Ankle fusion presents a difficult problem in the presence of infection and poor bone stock. The Ilizarov method provides stability with remote fixation and allows weight bearing. Patients and method Fourteen consecutive patients were studied (10 males, 4 females). The mean age at onset of disease was 50 years (range 4–70). Thirteen of the patients had either clinical or radiological evidence of infection prior to ankle fusion surgery. Mean duration of problem was 52 months (range 8–372). Aetiology included traumatic arthritis in five, failed fusion in six, septic arthritis in one, infected ankle fracture non-union in one and avascular necrosis of talus in one. Local excision was followed by Ilizarov frame compression. Diagnosis of infection was based on microbiology and histology. Antibiotic treatment was continued until union. On radiological evidence of union the frame was dynamized and removed. A below-knee cast was applied for 4 weeks. Results At a mean period of 5 months, complete ankle fusion was found in 13/14 patients. One patient who had partial fusion of the ankle had recurrence of infection requiring amputation. Complications included pin site infection, lateral impingement, deep infection, hind-foot pain and neuroma at amputation site. Conclusion The Ilizarov ankle fusion is a reliable salvage procedure in difficult ankle problems

Our Purpose is to present the results of treatment of 35 (thirty five) comminuted fractures of the diaphyses of Tibia and Fibula with combination of Orthofix External Fixator and Sarmiento Brace. In Syros General Hospital, during the last 8 (eight) years, 35 (thirty five) comminuted fractures of the Diaphyses of Tibia and Fibula were treated. Twenty were closed and 15 (fifteen) compound. Five were type 1, 8 (eight) type 2 and 2 type 3 Gustilo. Our Method : After a good surgical cleaning all fractures were reduced and stabilized with Orthofix External Fixator. We used two pins above and two pins below the fracture. According to the union of the fracture, we allowed partial weight bearing with dynamization. In three months the External Fixator was removed and a Sarmiento Brace was put. With the Brace we allowed full weight bearing until the fracture was united. Results: All fractures united. It took five months for the close and six months for the compound. There was no displacement in any fracture. In four fractures we had pin infection that was cured with antibiotics and lack of weight bearing for 15 days. Conclusion : Comminuted fractures of Tibia are a challenge for every Orthopaedic Surgeon. We believe that the combination of those two methods that are simple and safe solve the treatment of those difficult fractures

Aims: The purpose of this study is to evaluate the results of intrerlocking nailing (ILMN) as a þnal treatment of non septic femoral shaft pseudarthrosis. Material- Methods: The study involved 35 patiens suffering a femoral pseudarthrosis who underwent þxation with ILMN as a þnal treatment between 1999–2001. 31 male and 4 female individuals with a mean age of 25 years were followed up postoperatively for 24 months. Primary treatment had been done with plating in 29 pts, external þxation in 2 pts, AO nail in 3 and R-Tnail in one patient. The period between primary and þnal treatment ranged from 9 to 46 months. After the removal of primary þxation components all patients treated with ILMN for þxation but only 8 of them underwent autogenous bone grafting. Dynamic ILMN has been done in 32 out of 35 patiens (91%)Results: Clinical healing and radiological callus formation was apparent in all patiens after a period of 18 to 26 weeks (average time 20w). Serious complications were not observed. Light stiffness of the knee joint was noted in one and residual pain in distal metaphysis in two cases. Conclusions: The sort- term results from the use of LIN in treatment of femoral shaft pseudarthrosis have been more than encouraging. We recommend the reaming technique and the dynamization of the nail for optimal outcome. Bone grafting is not necessary

Aims: The purpose of this study is to examine the rate of pseudarthrosis and possible factors involving the healing of the fracture after interlocking nailing (ILMN) as treatment of femoral shaft fractures. We examined the type of the fractures, surgical pitfalls, complications, if the patients smoked cigarettes or tooled other medications and drugs. Methods: Between 1996–2001 we treated 165 patients who had 180 fractures of the femur shaft. In 4 out of our patients primary have treated using interlocking intramedullary nailing we occurred pseud-arthrosis. We have use AO nail in 3 patients and R-T nail in one patient. After the removal of primary nailing þxation components all patients treated with ILMN wider nail and autogenous bone grafting. The preferred method of stabilization is reamed interlocking intra-medullary nailing using AO Nail. Results: Radiological callus formation was apparent in all patients after a period of 18 to 26 weeks (average time 20w). Serious complications were not observed Stiffness of the knee joint was noted in one and pain in distal metaphysis in two cases. Conclusions: The sort-term results have been more than encouraging. We recommend the reaming technique and the dynamization of the nail for optimal outcome. Bone grafting is necessary according to our opinion. Several factors involved the healing of the femoral shaft fracture, after interlocking intramedullary nailing as primary treatment

Aims: Outcome of the distal tibial fractures treated with interlocking nail. Method: We reviewed 108 patients with distal tibial fractures which were treated in our clinic between 1990 using interlocking intramedullary nailing. 94 patients (63 men and 31 women) were found in the recent follow up. AO fracture classiþcation system was used Seventy-eight patients had concomitant fractures of the lateral malleolar and 4 had medial malleolar fractures. Eight (8,5%) of the fractures were open grade I. All fractures were managed with closed reamed nailing. In fourteen cases the nail had to be shortened. The lateral malleolar fractures were þxed before tibial nailing to ensure overall alignment. Results: Union was achieved in 89 (94,6%) fractures with a mean time of union of 4,2 months (range:3–10 months). One deep infection (1,06%) lead to nonunion. Three aseptic cases had delay union which required nail dynamization. In one more nonunion case bone grafting and þbulectomy required. Postoperative transient peroneal palsy occurred in 2 (2,12%) patients which were fully recovered. One patient developed deep posterior compartment syndrome leading to FHL conctracture, needed tendon lengthening. Conclusions: Interlocking intramedullary nailing is a reliable, safe and effective method of managing distal tibial fractures with or without minimal ankle joint involvement

Aim of this study: The aim of this prospective study was the evaluation of the results of intramedullary nailing with mild reaming for the treatment of closed tibial fractures. Patients and Method: During the period 2001–2003 a total of 22 closed tibial fractures were managed. Fractures were classified according to the AO system. The method of treatment was determined by the degree of comminution at the fracture site as well as of the presence or not of intact fibula. Dynamic nailing was performed for the treatment of 9 fractures type A, static nailing following dynamization in 4–6 weeks with the presence of radiological callus formation was performed for the treatment of 5 fractures type B with > 50% comminution and dynamic nailing was performed for the treatment of 8 fractures type B with < 50% comminution. In 2 cases with intact fibula (A31, B21) osteotomy of the fibula performed at the same time. The mean size of the reaming was 11mm for the total of cases. Results: The mean union time was 16 weeks, no infection or mechanical failure was recorded. Two cases of non-union were recorded (patient under anti-depression therapy and fracture type B23 in a patient with bilateral tibial fracture). Revision nailing were performed for these two cases (union in 14 and 16 weeks respectively). Conclusion: Intramedullary nailing with limited reaming is a valuable method for the management of closed tibial fractures, especially in high energy fractures. Osteotomy of the tibia improves the mechanical environment at the fracture site

The external fixation device has successfully been applied in comminuted and unstable fractures of the distal end of the radius. We used the fixator in Smith type fractures, since they are unstable and the literature is quite poor. Within 2 years, mean follow up time 13 months, we operated 21 patients (8 male, 13 female) aged 17–74 years (average 43 years) with Smith type fracture using Penning type external fixation device. The device remained for 6– 10 weeks (mean time of immobilization 8 weeks). early mobilization – dynamization was not applied to any of the cases. The final estimation was based on the Gartland and Werley score system and the results were characterized as very good (83%), good (13%) and poor (4%). In those with very good result extension-flexion, supination –pronation of the wrist as well as the power grip were completelly rehabilitated (compared to the healthy limb) within 6 months. In those with good results the outcome was approximately the same to the previous group, involving though complications such as superficial infection, loosening of the pins, 1 case of mild algodystrophy, sensitivity disorders of the radial nerve. All complications were faded after the removal of the device. Finally there was a case with lose of the reduction and malunion post the removal of the device, poor results due to the early (on the 3 week) mobilazation –dynamization of the wrist. Despite the good clinical and radiological results, treatment of Smith type fracture with the use of external fixation does not provide earlier and complication free rehabilitation of the wrist, so that should be used in certain cases only

We evaluated the clinical outcome of IM nailing for the treatment of femoral shaft pseudarthrosis in patients who had multiple failed plate osteosyntheses. From January 2000 untill April 2001, 20 (19 male-1 female, mean age 28) patients were treated because of femoral shaft non-union in our institution. All patients had two or more failed plate osteosyntheses. There were no septic non-unions in this group. Eight patients had an established non-union on an average of nine months post-op and the remaining eleven had radiological and clinical evidence of implant failure. There was no segmental bone loss, hi all patients the implants were removed and nailing was performed. Extensive periosteal stripping, bone necrosis and soft-tissue scaring were constant findings in all patients. Twelve patients received interlocking nails. Eight femurs were grafted with iliac crest bone graft. All patients were followed by serial x-rays until union. There were no postoperative complications. All pseudarthroses were healed within an average of 9.7 months (8–12). Non-unions which received bone graft (eight out of twenty) in day one, were healed faster than those which didn’t. There were no re-operations among these patients. Among the remaining ten patients five were grafted five to six months postoperatively and three had had nail dynamization. IM nailing for femoral shaft non-unions after multiple failed plate osteosyntheses is a safe and effective method of treatment. Autologous bone graft reduces healing time and re-operation rate