Controversy persists over whether cemented or uncemented fixation is more effective in reducing revision and mortality risks following primary total hip arthroplasty (THA). Despite a shift towards uncemented THA in Europe, Australia, and the US, no consensus exists on superior outcomes. This ambiguity in evidence from randomized controlled trials (RCTs) and observational studies necessitates advanced research methodologies to derive more definitive conclusions. This study investigates the causal impact of THA fixation type on 2-year and 5-year revision rates, along with 90-day mortality, utilizing a regression discontinuity (RD) design in scenarios where fixation choice is guided by patient age. Employing data from the Dutch Arthroplasty Register, we conducted a cohort study on primary THAs for osteoarthritis from 2007 to 2019. A “fuzzy” RD design was executed to compute the Local Average Treatment Effect for subjects around the age-based selection threshold for fixation type. The main outcome of interest was the revision rate at 2 years post-operation. Analysis for the 2-year revision endpoint, covering any cause, included 2,344 females and 1,671 males across 5 hospitals each, with no significant variation in revision rates observed. For the 5-year mark, 1,058 females in 3 hospitals and 214 males in 1 hospital were examined, similarly showing no significant differences. Mortality within 90 days post-operation was also investigated in 5 female and 7 male cohorts, with 2,180 and 2,145 surgeries respectively, yielding no substantial disparities. In conclusion, the RD analysis revealed no notable differences in revision rates at 2 and 5 years or in early mortality based on the fixation method used in THA. These outcomes suggest that the age-based preference for THA fixation may not influence the revision or mortality risk, underscoring the value of RD design in deriving causal insights from observational data

Abstract. Introduction. Isolated patellofemoral osteoarthritis accounts for 10% of knee osteoarthritis. Many of these will not require arthroplasty solutions, but for those who are sufficiently symptomatic, patellofemoral joint (PFJ) replacement has been shown to be an effective procedure. The National Joint Registry (NJR) has shown a higher revision rate for this operation, particularly in younger patients (males <55 years 13.3% failure at 5 years, females 9.6%). The aim of this study is to report on the medium-term outcome of the Avon patellofemoral joint arthroplasty in patients under 55 from a non-design centre. There is no other published case series on this young patient cohort. Methodology. 50 Avon PFJ replacements (Stryker, Kalamazoo USA) were undertaken in 46 patients under 55 years old (range 35 – 54, mean 48.8) between 2010 and 2022 for end-stage isolated PFJ arthritis shown on Xray and MRI scan. The outcome measure was all-cause revision rate. This was assessed by review of clinical notes, imaging and NJR data. Results. The mean follow up was 5.8 years (range 6 months to 12.9 years). Only one patient had a revision procedure (for progressive osteoarthritis) which was 3 years after the primary procedure. This patient has had no further surgery. The implant survival rate was 97.2% at 5 years and 97.2% at 10 years. Conclusion. This study shows that patellofemoral joint replacement with the Avon prosthesis can give a satisfactory revision rate in the medium term in patients under 55 if carefully selected

Abstract. Introduction. The role of patellar resurfacing in total knee arthroplasty remains controversial. We questioned the effect of patellar resurfacing on the early and late revision rates after total knee arthroplasty. Materials and Methods. We analysed the data of cumulative revisions of primary knee replacement from the NJR 19th Annual Report. NJR included secondary patellar resurfacing as a revision. We compared differences in the 3-year and 15-year revision rates between the patellar resurfacing and non-resurfacing for the different combinations of total knee replacements using a paired t-test. We performed subgroup analysis for the five combinations with the highest volumes. Results. Twenty-seven implant combinations had the 15-year revision rates reported. Patellar resurfacing group had lower mean 3-year revision rate of 1.68 (SD 0.7) compared to 2.02 (SD 0.9) in non-resurfacing group (p=0.05). However, 15-year revision rate was similar between the two groups (mean 5.7, SD 2.1 vs. mean 5.7, SD 2.2; p = 0.46). High volume implants showed that two combinations (NexGen CR and PS) had similar revision rates at 3 and 15 years between resurfacing and non-resurfacing groups. Three combinations (PFC Sigma CR and PS and Genesis 2 CR) had higher revision rate in non-resurfacing group at 3 years (p=0.01) and the difference persisted at 15 years (p=0.05). Conclusions. Although revision rate in total knee arthroplasty was higher without patellar resurfacing at 3 years, at 15 years the difference was not significant. However, the higher revision without patellar resurfacing can be prosthetic combination specific which surgeons need to be aware of

Instability and aseptic loosening are the two main complications after revision total hip arthroplasty (rTHA). Dual-mobility (DM) cups were shown to counteract implant instability during rTHA. To our knowledge, no study evaluated the 10-year outcomes of rTHA using DM cups, cemented into a metal reinforcement ring, in cases of severe acetabular bone loss. We hypothesized that using a DM cup cemented into a metal ring is a reliable technique for rTHA at 10 years, with few revisions for acetabular loosening and/or instability. This is a retrospective study of 77 rTHA cases with severe acetabular bone loss (Paprosky ≥ 2C) treated exclusively with a DM cup (NOVAE STICK; SERF, DÉCINES-CHARPIEU, FRANCE) cemented into a cage (Kerboull cross, Burch-Schneider, or ARM rings). Clinical scores and radiological assessments were performed preoperatively and at the last follow-up. The main endpoints were revision surgery for aseptic loosening or recurring dislocation. With a mean follow-up of 10.7 years [2.1-16.2], 3 patients were reoperated because of aseptic acetabular loosening (3.9%) at 9.6 years [7-12]. Seven patients (9.45%) dislocated their hip implant, only 1 suffered from chronic instability (1.3%). Cup survivorship was 96.1% at 10 years. No sign of progressive radiolucent lines were found and bone graft integration was satisfactory for 91% of the patients. The use of a DM cup cemented into a metal ring during rTHA with complex acetabular bone loss was associated with low revision rates for either acetabular loosening or chronic instability at 10 years. That's why we also recommend DM cup for all high risk of dislocation situations

Aims. The aim of this study was to conduct evidence synthesis on the available published literature of the impact of the training status of the operating surgeon (trainee vs. consultant) on the survival and revision rate of primary hip and knee replacements. Patients and Methods. We conducted a systematic review according to Cochrane guidelines. Separate searches were performed for hip and knee replacements, with meta-analysis and presentation of results in parallel. We searched MEDLINE and Embase databases from inception to 17 September 2019 and included controlled trials and cohort studies reporting implant survival estimates, or revision rates of hip and knee replacements according to the grade of the operating surgeon. This study was registered with PROSPERO (CRD42019150494). Results. 8 studies (5 hip papers and 3 knee papers) met the inclusion criteria. There was no significant difference in the survival estimates for total hip replacements (THRs) performed by trainees compared to consultants at 5-years follow-up (97.9% vs 98.1%, p = 0.74). Furthermore, there was no significant difference in the revision rate of THRs performed by trainees and consultants at both 5 and 10-year intervals of follow-up (relative risk [RR]: 5yrs = 0.88 (95% CI: 0.46, 1.70; P = 0.71); 10yrs = 0.68 (95% CI: 0.37, 1.26; P = 0.22)). There was no significant difference in the survival estimates at 10-years for total knee replacements (TKRs) performed by trainees compared to consultants (96.2% vs 95.1%, p=0.49). Conclusion. There is no evidence in the existing literature that trainee surgeons have worse outcomes than their consultant colleagues, in terms of the survival, or rate of revision of hip and knee replacements at 5–10 years follow-up. This may mean that there is genuinely no difference or that, in the context of contemporary training programmes, appropriate case-mix selection and supervision of trainees is currently employed

Modular femoral stems offer surgeons great flexibility in biomechanical configuration during total hip replacement (THR) however introduce a taper-trunnion articulation known to be a source of additional wear debris through crevice, fretting and galvanic corrosion with mixed material combinations. This study aimed to investigate the influence of the trunnion bearing surface combination on the revision rate following primary total hip replacement (THR). All patients who underwent THR using an Exeter V40 cemented stainless steel stem and monobloc cemented polyethylene acetabular component (uncemented cups excluded to standardise the acetabular bearing surface and fixation) between January 2003 and December 2019 were extracted from the National Joint Registry for England, Wales, Northern Ireland, and the Isle of Man. The primary exposure was the head substrate used corresponding to the trunnion bearing. Time-to-event was determined by duration of implantation from primary surgery to revision with cases censored at death or end of available follow-up. Multivariable Cox proportional hazard models were used to identify predictors of all cause revision, adjusted for age, sex, American Association of Anaesthesiologists (ASA) grade, body mass index, surgical indication (osteoarthritis or other), and femoral head size. 229,870 THR were identified (66% female, mean age 73.4 years (SD 9.1) with the majority (91%) performed for osteoarthritis of which 4,598 were revised. Mean time from primary to revision or censoring was 6.8 years (SD 4.0). Multivariable modelling showed CoCr/SS trunnions were associated with a significantly higher risk of revision (hazard ratio (HR) 1.31 (95%CI 1.15 to 1.48, p<0.0001) as compared to SS/SS (reference). Both Alumina/SS (HR 0.74 (0.65 to 0.84), p<0.0001) and Zirconia/SS (HR 0.61 (0.49 to 0.74), p<0.0001) were associated with a significantly lower risk of revision. Ceramic heads on an Exeter stem were associated with significantly improved survivorship compared to metal heads in primary THR. CoCr/SS trunnion articulations had the poorest survivorship which may be contributed to by trunnionosis

Introduction. While advances in joint-replacement technology have made total ankle arthroplasty a viable treatment for end-stage arthritis, revision rates for ankle replacements are higher than in hip or knee replacements [1]. The questions asked in this study were (1) what retrieved ankle devices demonstrate about ankle arthroplasty failures, and (2) how do these failures compare to those seen in the hip and the knee?. Materials and Methods. An IRB-approved retrieval laboratory received retrieved polyethylene inserts and surgeon-supplied reason for revision from 70 total-ankles (7 designs, including five currently-marketed designs) from 2002 to the present. All retrievals were rated for clinical damage. Polyethylene inserts received six months or less after retrieval (n=45) were analyzed for oxidation using Fourier Transform Infrared (FTIR) spectroscopy, reported as maximum ketone oxidation index [2]. Insert sterilization method was verified using trans-vinylene index [3]. Oxidation measured in the 45 ankle inserts versus their time in vivo was compared to oxidation rates previously published for gamma-sterilized hip and knee polyethylene retrievals [6]. Statistical analysis was performed using IBM SPSS v.22. Results. The ankle devices were retrieved most commonly for loosening (n=22) followed by polyethylene fracture (n=9). These failure modes occurred after statistically different in vivo time (loosening: mean=4.4±3.6 years; polyethylene insert fracture: mean=9.5±4.1 years; p=0.002). Presence of clinical fatigue (cracking and/or delamination) was identified in 24 of the 70 retrieved inserts, and its presence correlated with in vivo time (Spearman's rho =0.449, p<0.001). Thirteen of these fatigued inserts were analyzed by FTIR. TVI analysis confirmed the sterilization method of the fatigued inserts: 12 gamma, 1 non-gamma sterilized. All 13 fatigued inserts had maximum ketone oxidation index (KOI) of 1.2 or higher. Presence of fatigue correlated with measured oxidation (Spearman's rho =0.685, p<0.001). Six of the 9 inserts that fractured in vivo were analyzed by FTIR. All were gamma-sterilized, and all had oxidation of 1.2 or higher. Oxidation rate determined for most of the 45 ankle inserts was at or above oxidation rates previously published for gamma-sterilized hip and knee polyethylene retrievals [6]. Discussion. This retrieval study concurs with the ankle arthroplasty literature that loosening is the most common reason for ankle revision [4]. Ankle inserts retrieved as a result of implant loosening had lower oxidation and no fatigue damage resulting from their shorter in vivo time. Fatigued and/or fractured inserts were in vivo for longer times, allowing more oxidation to occur. The effect of oxidation on polyethylene tensile strength and ductility has been reported for tibial inserts [5]. Oxidation above the critical value [5] has a dramatic effect on the ability of the polyethylene to resist fatigue damage and fracture, since the toughness of the polyethylene drops to near zero. All fatigued and fractured ankle inserts had oxidation that exceeded this critical oxidation. Most ankle inserts, whether gamma or non-gamma sterilized, oxidized at or above the oxidation rates previously published for gamma-sterilized hip and knee polyethylene retrievals [6]

There is increasing focus on publishing comparable data for individual hospitals and surgeons. The Dr Foster website is one portal for accessing such information, and uses hospital episode statistics sent to the Department of Health. For 2008–2011 our Trust was labelled as a statistical outlier with high one year revision rates for total knee replacement; relative risk was 2.53. We examined the accuracy of this information. According to Dr Foster's data, out of 1517 primary total knee replacements performed between April 2008 and March 2011, fifty-five were revised within one year (29 female: 26 male). This gave a revision rate of 3.6% compared to a 1.4% national average. We reviewed patient records for those labelled as revisions. Of these cases, only one was a revision total knee replacement within one year. Forty-four had a manipulation under anaesthesia for stiffness and the remaining cases had alternative operations such as arthroscopic washout. For our Trust, therefore, the data is inaccurate, and a patient relying on such data would be misled. Either Trusts should work with Dr Foster to improve accurate coding of data, or they should keep ownership of their data, and publish accurate figures of their own

Aims

Despite multiple trials and case series on hip hemiarthroplasty designs, guidance is still lacking on which implant to use. One particularly deficient area is long-term outcomes. We present over 1,000 consecutive cemented Thompson’s hemiarthroplasties over a ten-year period, recording all accessible patient and implant outcomes.

Prosthetic joint infections (PJI) are a devastating consequence in total hip arthroplasties (THA) with both significant morbidity and sometimes mortality, posing a significant health economic burden. Studies, both clinical and in-vitro have suggested possible reduction in PJI with the use of ceramic bearings. We have investigated the relationship of ceramic-on-ceramic (CoC), ceramic-on-polyethylene (CoP) or metal-on-polyethylene (MoP) bearing surface in affecting outcome of revision surgery after primary THA using data collected from National Joint Registry for England and Wales, Northern Ireland and the Isle of Man between 2002 and 2016. We used a competing risk regression model to investigate predictors of each revision outcome, such as infection, dislocation, aseptic revision and all cause revisions. The results were adjusted for age, gender, ASA grade, BMI, indication for surgery, intraoperative complications and implant data. We identified 456,457 THA (228,786 MoP, 128,403 CoC and 99,268 CoP). In a multivariable model, the adjusted risk of revision for PJI was lower with CoC (OR-0.748, p<0.001) and CoP (OR-0.775, p<0.001) when compared to MoP bearing. Additionally there was also a significant reduction in the risk of all cause revision for CoC (OR-0.918, p=0.002) and CoP (0.806, p<0.001), bearings as compared with MoP. The protective effect of ceramic bearing was predominantly seen after two years of implantation with a significant (p<0.0001) reduction of revision for PJI in both CoC (by 42.8%) and CoP (by 41.3%) group. Similarly significant effect was seen for aseptic revision beyond two years and overall all cause revision rate beyond two years reduced by 21.6% for CoC and 27.1% for CoP (p<0.001). Within the limits of registry analysis, this study has demonstrated an association between the use of ceramic bearing and lower rates of revision for all cause revisions especially infection and aseptic loosening. This finding supports the use of ceramic bearings in THA

Patients ≤ 55 years have a high primary TKA revision rate compared to patients >55 years. Guided motion knee devices are commonly used in younger patients yet outcomes remain unknown. In this sub-group analysis of a large multicenter study, 254 TKAs with a second-generation guided motion knee implant were performed between 2011–2017 in 202 patients ≤ 55 years at seven US and three European sites. Revision rates were compared with Australian Joint Registry (AOANJRR) 2017 data. Average age 49.7 (range 18–54); 56.4% females; average BMI 34 kg/m2; 67.1% obese; patellae resurfaced in 98.4%. Average follow-up 4.2 years; longest follow-up six years; 27.5% followed-up for ≥ five years. Of eight revisions: total revision (one), tibial plate replacements (three), tibial insert exchanges (four). One tibial plate revision re-revised to total revision. Revision indications were mechanical loosening (n=2), infection (n=3), peri-prosthetic fracture (n=1), and instability (n=2). The Kaplan-Meier revision estimate was 3.4% (95% C.I. 1.7% to 6.7%) at five years compared to AOANJRR rate of 6.9%. There was no differential risk by sex. The revision rate of the second-generation guided motion knee system is lower in younger patients compared to registry controls

A long surgical procedure length has been well associated with worse clinical outcomes, also in an economic climate where in the theatre, time is money, surgical procedures are done very rapidly. Few studies have documented the clinical outcomes of procedure speed. Using the New Zealand Registry we reviewed the operation time of 41,560 primary knee joint replacements. These were split into groups of time slots for the surgery from less than 40 minutes, 40–59, 60–89, 90–119, 120–179 and greater than 180mins. This was referenced to the oxford knee scores obtained and the revision rate. For operations done in less than 40 or greater than 180 minutes, the oxford knee score was lower by 5 years. The revision rate was also increased in these same groups. Operations done in greater than 180 minutes are generally the more complex non-osteoarthrtic and tumour cases and have a higher revision rate reflecting their complexity. Procedures done less than 40 minutes are more straight forward, but there is a relationship shown between this speed and revision rate and poorer outcome. The cause is likely multifactorial, but begs the question, does speed kill?

Objective. To evaluate the volume of cases, causes of failure, complications in patients with a failed Thompson hemiarthroplasty. Methods. A retrospective review was undertaken between 2005–11, of all Thompson implant revised in the trust. Patients were identified by clinical coding. All case notes were reviewed. Data collection included patients demographic, time to revision, reason for revision, type of revision implant, surgical time and technique, transfusion, complications, HDU stay, mobility pre and post revision,. Results. 23 patients were identified, age 81 years (range 76–90). male to female ratio was 2:21, 11 right and 12 left hip. Mean time to failure was 50 months (1–104 m) range, mean follow up post revision surgery 26 months (3–77). Reason for revision was dislocation in 3 patients (13%), femoral loosening 5 (21%), peri-prosthetic fracture 3 (13%), Infection 6 (26%) and acetabular erosion 6 (26%). There were six infected cases in the study which was all aspirated preoperatively off which only 4 were positive. All infected cases grew an organism from intra-operative specimens. (80% cases) were coagulase negative Staphylococcus aureus. 35% only positive on enrichment cultures. 4 infected Thompsons were revised successfully with 2 stage revisions. One patient died after 1. st. stage and another was able to mobilise after the first stage with a cement spacer and refused further surgery. Mean surgical time was 3.5 hours (range 2.5–5.5). HDU stay 1.3 days (range 0–6). 6 deaths in total, 3 unrelated, 3 post operative. Complications included 1 fracture requiring revision, 1 dislocation, 1 foot drop and 4 chest infection of which two patients died from this. Conclusion. We identified a revision rate of 1.2%, complication occurred in 43% of cases with a one year mortality of 26%. Failed Thompson revision surgery is rare, challenging and patient selection is important to reduce postoperative morbidity and mortality

Introduction. High BMI has been classically regarded as a contraindication for unicompartmental knee arthroplasty (UKA) as it can potentially lead to poor clinical outcomes and a higher risk of failure. In recent years, UKA has increased in popularity and, as a result, patient selection criteria are beginning to broaden. However, UKA performed manually continues to be technically challenging and surgical technique errors may result in suboptimal implant positioning. UKA performed with robotic assistance has been shown to improve component positioning, overall limb alignment, and ligament balancing, resulting in overall improved clinical outcomes. The purpose of this study is to examine the effect of high BMI in patients receiving UKA with robotic assistance. Methods. 1007 patients (1135 knees) were identified in an initial and consecutive multi-surgeon multi-center series receiving robotically assisted medial UKA, with a fixed bearing metal backed onlay tibial component. As part of an IRB approved study, every patient in the series was contacted at a minimum two year (±2 months) follow up and asked a series of questions to determine implant survivorship and satisfaction. 160 patients were lost to follow up, 35 patients declined to participate, and 15 patients were deceased. 797 patients (909 knees) at a minimum two year follow up enrolled in the study for an enrollment rate of 80%. 45% of the patients were female. The average age at time of surgery was 69.0 ± 9.5 (range: 39–93). BMI data was available for 887 knees; the average BMI at time of surgery was 29.4 ± 4.9. Patients were stratified in to five categories based on their BMI: normal (< 25; 16%), overweight (25–30; 46%), obese class I (30–35; 25%), obese class II (35–40; 11%) and obese class III (>40; 2%). Results. Across all BMI groups, nine knees were reported as revised at two years post-operative yielding a two year revision rate of 0.99%, 4 in the overweight group, 2 in the obese class I group and 3 in the obese class II group. There was no significant difference in the rate of revision between the BMI groups (c. 2. (4, N = 887) = 6.04, p = 0.20). Of the 3 revisions for tibial component loosening, one occurred in the overweight group, one in the obese group and one in the morbidly obese group. The overall patient satisfaction rate for the entire population was 92% with the following distribution: normal: 92%, overweight: 93%, obese class I: 92%, obese class II: 87% and obese class III: 83%. While the most severely obese patients tended to be less satisfied, this was not statistically significant between the groups (c. 2. (4, N = 887) = 5.12, p = 0.27). Conclusion. These results suggest that BMI does not effect the survivorship or the satisfaction of patients undergoing robotically assisted UKA. Advancement in UKA implant designs and improvements in surgical technique may help to broaden indications and patient selection for UKA. This study will continue to track patients mid to long term to determine the longer term effect of robotically assisted UKA on high BMI patients

Introduction. Patients ≤ 55 years have a high primary TKA revision rate compared to patients >55 years. Guided motion knee devices are commonly used in younger patients yet outcomes remain unknown. Materials and Methods. In this sub-group analysis of a large multicenter study, 254 TKAs with a second-generation guided motion knee implant (Journey II Bi-Cruciate Stabilized Knee System, Smith & Nephew, Inc., Memphis) were performed between 2011–2017 in 202 patients ≤ 55 years at seven US and three European sites. Revision rates were compared with Australian Joint Registry (AOANJRR) 2017 data. Results. Average age 49.7 (range 18–54); 56.4% females; average BMI 34 kg/m. 2. ; 67.1% obese; patellae resurfaced in 98.4%. Average follow-up 4.2 years; longest follow-up six years; 27.5% followed-up for ≥ five years. Of eight revisions: total revision (one), tibial plate replacements (three), tibial insert exchanges (four). One tibial plate revision re-revised to total revision. Revision indications were mechanical loosening (n=2), infection (n=3), peri-prosthetic fracture (n=1), and instability (n=2). The Kaplan-Meier revision estimate was 3.4% (95% C.I. 1.7% to 6.7%) at five years compared to AOANJRR rate of 6.9%. There was no differential risk by sex. Discussion. Reasons for high TKA revision rates in younger patients remain unknown. Conclusion. The revision rate of the second-generation guided motion knee system is lower in younger patients compared to registry controls

Aims. The aims of the study were to report for a cohort aged younger than 40 years: 1) indications for HRA; 2) patient-reported outcomes in terms of the modified Harris Hip Score (HHS); 3) dislocation rate; and 4) revision rate. Methods. This retrospective analysis identified 267 hips from 224 patients who underwent an hip resurfacing arthroplasty (HRA) from a single fellowship-trained surgeon using the direct lateral approach between 2007 and 2019. Inclusion criteria was minimum two-year follow-up, and age younger than 40 years. Patients were followed using a prospectively maintained institutional database. Results. A total of 217 hips (81%) were included for follow-up analysis at a mean of 3.8 years. Of the 23 females who underwent HRA, none were revised, and the median head size was 46 mm (compared to 50 mm for males). The most common indication for HRA was femoroacetabular impingement syndrome (n = 133), and avascular necrosis ( (n = 53). Mean postoperative HHS was 100 at two and five years. No dislocations occurred. A total of four hips (1.8%) required reoperation for resection of heterotopic ossification, removal of components for infection, and subsidence with loosening. The overall revision rate was 0.9%. Conclusion. For younger patients with higher functional expectations and increased lifetime risk for revision, HRA is an excellent bone preserving intervention carrying low complication rates, revision rates, and excellent patient outcomes without lifetime restrictions allowing these patients to return to activity and sport. Thus, in younger male patients with end-stage hip disease and higher demands, referral to a high-volume HRA surgeon should be considered. Cite this article: Bone Jt Open 2023;4(6):408–415

Aims. Despite higher rates of revision after total hip arthroplasty (THA) being reported for uncemented stems in patients aged > 75 years, they are frequently used in this age group. Increased mortality after cemented fixation is often used as a justification, but recent data do not confirm this association. The aim of this study was to investigate the influence of the design of the stem and the type of fixation on the rate of revision and immediate postoperative mortality, focusing on the age and sex of the patients. Methods. A total of 333,144 patients with primary osteoarthritis (OA) of the hip who underwent elective THA between November 2012 and September 2022, using uncemented acetabular components without reconstruction shells, from the German arthroplasty registry were included in the study. The revision rates three years postoperatively for four types of stem (uncemented, uncemented with collar, uncemented short, and cemented) were compared within four age groups: < 60 years (Young), between 61 and 70 years (Mid-I), between 71 and 80 years (Mid-II), and aged > 80 years (Old). A noninferiority analysis was performed on the most frequently used designs of stem. Results. The design of the stem was found to have no significant influence on the rate of revision for either sex in the Young group. Uncemented collared stems had a significantly lower rate of revision compared with the other types of stem for females in the Mid-I group. There was a significantly higher rate of revision for uncemented stems in females in the Mid-II group compared with all other types of stem, while in males the rate for uncemented stems was only significantly higher than the rate for cemented stems. Cemented stems had a significantly lower revision rate compared with uncemented and short stems for both sexes in the Old cohort, as did females with collared stems. The rate of immediate postoperative mortality was similar for all types of stem in the Old age group, as were the American Society of Anesthesiologists grades. Conclusion. In patients aged > 80 years, uncemented and short stems had significantly higher revision rates compared with cemented and collared stems, especially in females. The design of the stem and type of fixation have to be analyzed in more detail than only considering cemented and uncemented fixation, in order to further improve the success of THA. Cite this article: Bone Joint J 2024;106-B(3 Supple A):130–136

Introduction. Since the early days of total hip arthroplasty (THA) the choice of the proper diameter of the femoral head has been debated with respect to its effect on wear. The most widely accepted theory explaining aseptic loosening of THA is that of polyethylene particles induced osteolysis. In a previous study concerning 1,660 ScanHip THA’s that were followed for up to 12 years the cumulative revision rate was not found to be dependent on if a 22 mm or a 32 mm head size had been used1. We have reexamined these patients to see whether a longer follow-up time (9–21 years) would disclose an effect of head size on the revision rate. Patients and Methods. We analyzed the CRR for 1,720 Scan Hip. ®. Classic I THA implanted in 1,550 patients, with 22 and 32mm heads, performed at Lund University Hospital during 1983 to 1995. Patients with the 3 most common diagnoses were included in the analysis, i.e. osteoarthritis, rheumatoid arthritis and femoral neck fracture. The end-point was defined as revision of any component for aseptic loosening before the end of 2004. Results. Using the life table method analyzed cumulative revision rate for osteoarthritis, femoral neck fracture and rheumatoid arthritis patients and found that the 32 mm head had higher cumulative revision rate (p=0.04 (Wilcoxon)). Further analysis with Cox regression adjusting for age and sex showed that the 32 mm head had 2.8 times greater risk of revision (CI 1.7–4.6), p< 0.001. For each year increase in age the risk of revision was reduced 0.96 times (CI 0.95 – 0.97), p< 0.001, males had 1.5 times (CI 1.1 – 2.1), p=0.01 greater risk of revision than females. Discussion. The reason that we did not find any significant difference in cumulative revision rates when followed up to 12 years, depending on head size in previous study (. Kesteris et al. 1998. ) may be the time it takes for wear particles to induce the chain of events, eventually ending up in loosening. However extended follow-up up to 21 years after THA revealed significant differences in cumulative revision rates depending on head size

Introduction. We previously reported a 28% short-term corrosion-related revision rate of recalled Rejuvenate modular stem. The purpose of this study was to assess the mid-term clinical results and survivorship of this implant. Methods. Between June 2009 and July 2012, 73 total hip arthroplasty (THA) in 63 patients with the Rejuvenate modular neck implant were performed by a single surgeon and prospectively followed. Average age was 63.2 ± 12.6 years (28 to 86). Elevated metal ion (= 2 µg/L), pain, or positive MRI findings were indication for revision surgery. Correlation between patient factors with serum metal ion levels and revisions were analyzed. Results. At an average follow-up of 4.2 ± 0.6 years (3.0 to 5.5), 57 hips (48 patients, 78%) were revised at mean of 3.2 ± 1 years (1 to 5.5); and 6 other have been scheduled for surgery. The Kaplan-Meier survivorship was 22 % at 5.5 years. Visible corrosion was seen at the trunion-stem junction in each revision case. 51 of 57 hips undergoing revision (89%), had elevated preoperative serum Co levels, 24 (42%) had elevated preoperative Cr. The average serum Co and Cr ion levels prior to revision surgery were 10 ± 8 µg/L (0.3 to 40) and 2.3 ± 1.5 µg/L (1 to 7.4), respectively. There was a significant correlation between revision surgery and younger age (p=0.0137). 52 hips underwent MRI evaluation, 22 hips (42%) had positive findings correlated to pain (p=0.025): 11 hips demonstrated adverse local soft tissue reactions such as fluid collection, capsular thickening, osteolysis, or synovitis, and 11 hips showed evidence of pseudotumor. Conclusions. At mid-term follow-up, 86% of the Rejuvenated modular neck stems have been revised or awaiting revision. Given these findings, all patients with a Rejuvenate modular neck stem implant should be followed closely and advised of impending failure

Total Hip Arthroplasty (THA) is a successful operation for the management of end stage hip osteoarthritis (OA) but long term success is limited by wear of the polyethylene bearing surface. The aim of this study was to compare the rate of revision at 15 years in patients <55 who had a THA for OA, and received either cross-linked (XLPE) or conventional non cross-linked polyethylene (non-XLPE). The study population was all patients with primary THAs undertaken for OA from 1999 to 31 December 2016. Outcomes were determined for all procedures, comparing THA performed with non-XLPE and XLPE and including the effect of age, sex, and reason for revision. The principal outcome measure was time to first revision using Kaplan-Meier estimates of survivorship. There were 17,869 procedures recorded for younger patients <55 years of age undergoing THA for OA and using either non XLPE or XLPE. There was a fivefold increase in the rate of revision for procedures using non-XLPE after seven years. The 15 year cumulative percent revision of primary THA performed for OA in patients <55 with non XLPE was 17.4% (95% CI 15.5,19.5) and for XLPE was 6.6% (95%CI 5.5,7.8) HR >7 years =5.3, p<0.001. Non-XLPE and XLPE were combined with three different femoral head bearing surfaces: ceramic, metal and ceramicised metal. Within each bearing surface, XLPE had a lower rate of revision than non-XLPE. For the most common head size of 28mm XLPE had a lower rate of revision. The use of XLPE has resulted in a significant reduction in the rate of revision for younger patients undergoing THA for OA at 15 years. This evidence suggests that longevity of THA is likely to be improved and may enable younger patients to undergo surgery, confident of a reduced need for revision in the long term