Aims. To fully quantify the effect of posterior tibial slope (PTS) angles on joint kinematics and contact mechanics of intact and anterior cruciate ligament-deficient (ACLD) knees during the gait cycle. Methods. In this controlled laboratory study, we developed an original multiscale subject-specific finite element musculoskeletal framework model and integrated it with the tibiofemoral and patellofemoral joints with high-fidelity joint motion representations, to investigate the effects of 2.5° increases in PTS angles on joint dynamics and contact mechanics during the gait cycle. Results. The ACL tensile force in the intact knee was significantly affected with increasing PTS angle. Considerable differences were observed in kinematics and initial posterior femoral translation between the intact and ACLD joints as the PTS angles increased by more than 2.5° (beyond 11.4°). Additionally, a higher contact stress was detected in the peripheral posterior horn areas of the menisci with increasing PTS angle during the gait cycle. The maximum tensile force on the horn of the medial meniscus increased from 73.9 N to 172.4 N in the ACLD joint with increasing PTS angles. Conclusion. Knee joint instability and larger loading on the medial meniscus were found on the ACLD knee even at a 2.5° increase in PTS angle (larger than 11.4°). Our biomechanical findings support recent clinical evidence of a high risk of failure of ACL reconstruction with steeper PTS and the necessity of ACL reconstruction, which would prevent meniscus tear and thus the development or progression of osteoarthritis. Cite this article: Bone Joint Res 2022;11(10):739–750

Background. The posterior slope of the tibial component in total knee arthroplasty (TKA) has been reported to vary widely even with computer assisted surgery. In the present study, we analyzed the influence of posterior tibial slope on one-year postoperative clinical outcome after posterior-stabilized (PS) -TKA to find out the optimal posterior slope of tibial component. Materials and Method. Seventy-three patients with varus type osteoarthritic (OA) knees underwent PS-TKA (Persona PS. R. ) were involved in this study. The mean age was 76.6 years old and preoperative HKA angle was 14.3 degrees in varus. Tibial bone cut was performed using standard extra-medullary guide with 7 degrees of posterior slope. The tibial slopes were radiographically measured by post-operative lateral radiograph with posterior inclination in plus value. The angle between the perpendicular line of the proximal fibular shaft axis and the line drawn along the superior margin of the proximal tibia represented the tibial slope angle. We assessed one-year postoperative clinical outcomes including active range of motion (ROM), patient satisfaction and symptoms scores using 2011 Knee Society Score (2011 KSS). The influences of posterior tibial slope on one-year postoperative parameters were analyzed using simple linear regression analysis (p<0.05). Results. The average posterior tibial slope was 6.4 ± 2.0 °. The average active ROM were −2.4 ± 6.6 ° in extension and 113.5± 12.6 ° in flexion. The mean one-year postoperative patient satisfaction and symptom scores were 29.3 ± 6.4 and 19.6 ± 3.9 points respectively. The active knee extension, satisfaction and symptom scores were significantly negatively correlated to the posterior tibial slope (r = −0.25, −0.31, −0.23). Discussion. In the present study, we have found significant influence of the posterior tibial slope on the one-year postoperative clinical outcomes in PS-TKA. The higher posterior slope would induce flexion contracture and deteriorate patient satisfaction and symptom. We had reported that the higher tibial posterior slope increased flexion gap and the component gap change during knee flexion in PS-TKA. Furthermore, another study reported that increase of the posterior tibia slope reduced the tension in the collateral ligaments and resulted in the knee laxity at flexion. The excessive posterior slope of tibial component would result in flexion instability, and adversely affected the clinical results including patient satisfaction and symptom. Conclusion. In the PS-TKA for varus type OA knees, excessive tibial posterior slope was found to adversely affect one-year postoperative knee extension and clinical outcome including patient satisfaction and symptom. Surgeons should aware of the importance of tibial slope on one-year postoperative clinical results and pay more attentions to the posterior tibial slope angle not to be excessive

Abstract. Purpose. Recently several authors have suggested a correlation between posterior tibial slope (PTS) and sagittal stability of the knee. However, there is a lack of consensus in the literature relating to measurement, normal values and important values to guide treatment. We performed a systematic literature review looking at PTS and cruciate ligament surgery. Our aim was to define a gold standard measurement technique, determine normal ranges and important values for consideration during cruciate ligament surgery. Methods. Electronic searches of MEDLINE (PubMed), CINAHL, Cochrane, Embase, ScienceDirect, and NICE in June 2020 were completed. Inclusion criteria were original studies in peer-reviewed English language journals. A quality assessment of included studies was completed using the Methodological Index for Non-Randomized Studies (MINORS) Criteria. Results. Two-hundred and twenty-one papers were identified; following exclusions 34 papers were included for data collection. The mean MINORS score for non-comparative studies was 13.8 and for comparative studies 20.4, both indicating fair to good quality studies. A large variation in PTS measurement technique was identified, resulting in a wide range of values reported. In addition, there appears to be significant variation between different races, ages and genders. Conclusion. We demonstrated a lack of consensus in the literature relating to various facets of PTS. Cautiously, we suggest normal ranges of 6–12º using the proximal tibia axis at 5 and 15cms below the joint. Potentially 12º is an important cute-off for slope reducing osteotomy as an adjunct to revision ACL reconstruction

Anthropometric anatomical factors may influence mechanical and functional stability of joints. An increased posterior tibial slope places the anterior cruciate ligament at a theroretical biomechanical disadvantage. An increased posterior tibial slope can potentially alter forces during landing tasks by either increasing anterior tibial translation and/or ACL loading. The purpose of this study is to investigate the relationship between posterior tibial slope and anterior cruciate ligament injuries. It is hypothesised that subjects with an ACL injury have an increased posterior tibial slope compared to a normal population. Posterior tibial slope in 211 patients (154 male, 57 female), aged 15–49, who underwent anterior cruciate ligament reconstruction was measured using the posterior tibial cortex as reference. A matched control group was used for comparison. The average posterior tibial slope in the ACLR population was 6.1 degrees, whilst the control group had average values of 5.4 degrees. This finding nearly reached statistical significance (p=0.057). In the male population, average values were 5.5 degrees in the ACLR group and 5.9 in the control group. This was not significant (p=0.21). However, there was a significant difference (p=0.04) in the female group. ACLR females had higher values 6.5 degrees whereas the control group had average values of 5.2 degrees. Increased posterior tibial slope decreases the inclination of the ACL and potentially decreases vector force during dynamic tasks. We could not confirm the results of previous studies demonstrating an increased degree of posterior tibial slope in ACL injured patients. However, we demonstrated a significant difference in tibial slope in females. Based on our results, an increased posterior tibial slope is not a risk factor in males but possibly contributes to ACL injuries in females. Increased posterior tibial slope may be one of the reasons why females have a higher incidence of ACL injuries

Abstract. Introduction. High posterior tibial slope (PTS) has been recognised as a risk factor for anterior cruciate ligament rupture and graft failure. This prospective randomised study looked at intra-operative findings of concomitant intra-articular meniscal and chondral injuries during a planned ACL reconstruction. Material and Methods. Prospective data was collected as part of a randomised trial for ACL reconstruction techniques. Intra-operative data was collected and these findings were compared with the PTS measured on plain radiograph by a single person twice through a standardised technique and intra-observer analysis was performed. Results. 49 confirmed ACL rupture patients were in the trial. The average age was 34 (23–66) years and 12 patients were female. 17 patients (34%) had PTS of 12 degrees or more. The intra-observer analysis for PTS measurements in a 2-sided paired T test, showed a mean difference of 0.03 degrees with a P value = 0.83. 23 patients had medial meniscal pathology identified, 15 (65%) had a PTS <12 degrees. 16 patients had lateral meniscus pathology and 9 (56%) had a PTS <12 degrees. Chondral damage did not appear significantly different in the two groups (<12 degrees 15% vs >12 degrees 23%). Conclusion. In this sample, a PTS >12 degrees was not associated with a higher incidence of meniscal or chondral damage after a confirmed ACL rupture

Introduction: Anthropometric anatomical factors may influence mechanical and functional stability of joints. An increased posterior tibial slope places the anterior cruciate ligament at a theroretical biomechanical disadvantage. An increased posterior tibial slope can potentially alter forces during landing tasks by either increasing anterior tibial translation and/or ACL loading. The purpose of this study is to investigate the relationship between posterior tibial slope and anterior cruciate ligament injuries. It is hypothesized that subjects with an ACL injury have an increased posterior tibial slope compared to a normal population. Methods: Posterior tibial slope in 211 patients (154 male, 57 female) aged 15–49 who underwent anterior cruciate ligament reconstruction was measured using the posterior tibial cortex as reference. A matched control group was used for comparison. Results: The average posterior tibial slope in the ACLR population was 6.1 degrees while the control group had average values of 5.4 degrees. This finding nearly reached statistical significance (p=0.057). In the male population average values were 5.5 degrees in the ACLR group and 5.9 in the control group. This was not significant (p=0.21). However there was a significant difference (p=0.04) in the female group. ACLR females had higher values 6.5 degrees whereas the control group had average values of 5.2 degrees. Discussion: Increased posterior tibial slope decreases the inclination of the ACL and potentially decreases vector force during dynamic tasks. It may further result in suboptimal length-tension relationships of agonistic muscles, increases in electromechanical delays and result in lower force development further leading to increased vector forces on the ACL. Posterior tibial slope angles were slightly smaller than with other published studies. However by using the posterior tibial cortex as reference an average of 3 degrees must be added to the measured values. We could not confirm the results of previous studies demonstrating an increased degree of posterior tibial slope in ACL injured patients. However we demonstrated a significant difference in tibial slope in females. Based on our results an increased posterior tibial slope is not a risk factor in males but possibly contributes to ACL injuries in females. Increased posterior tibial slope may be one of the reasons why females have a higher incidence of ACL injuries

Introduction. The influences of posterior tibial slope on the knee kinematics have been reported in both TKA and UKA. We hypothesized the posterior tibial slope (PTS) would affect the sagittal knee alignment after UKA. The influences of PTS on postoperative knee extension angle were investigated with routine lateral radiographies of the knee after UKA. Materials & Methods. Twenty-four patients (26 knees; 19 females, 7 males) underwent medial UKA were involved in this study. Average age was 74.8 ± 7.2 years. The mean preoperative active range of motion were − 4.1° ± 6.3°in extension and 123.2° ± 15.5° in flexion. All UKAs were performed using fixed bearing type UKA (Zimmer Biomet, ZUK), with adjusting the posterior slope of the proximal tibial bone cut according to the original geometry of the tibia. Routine lateral radiographies of the knee were examined preoperatively, 6 months after the surgery. PTS and knee extension angles with maximal active knee extension (mEXT) and one-leg standing (sEXT) were radiographically measured. We used the fibular shaft axis (FSA) for the sagittal mechanical axis of the tibia. PTS was defined as the angle between the medial tibial plateau and the perpendicular axis of FSA. Extension angles (mEXT and sEXT) were defined as the angles between FSA and distal femoral shaft axis (positive value for hyperextension). The changes of PTS and the influences of PTS on sEXT at each time period were analyzed using simple linear regression analysis (p<0.05). Results. The mean PTSs were 10.0° ± 3.0° and 9.9° ± 2.7° preoperatively, 6m after surgery respectively. The mean mEXTs were −4.1° ± 6.3° and −2.0° ± 5.4°, and sEXTs were −9.4° ± 7.6° and −7.3° ± 6.7° at each time period. Preoperative and postoperative PTS had positive correlation (r = −0.65). PTS significantly negatively correlated to sEXT at 6 months after the surgery (r = −0.63). Discussions. We found patient tended to stand with slight knee flexion (sEXT) which was smaller than the flexion contracture measured by mEXT. Interestingly, postoperative PTS significantly correlated to the knee flexion angle during one-leg standing. Patients with the higher PTS after UKA were more likely to stand with the higher knee flexion. The higher PTS had been reported to increase tibial anterior translation and strain or tear of the anterior cruciate ligament with load bearing in the normal knee. Slight knee flexion during one-leg standing would be beneficial to keep the joint surface parallel to the ground depending on PTS and reduce the anterior shearing force on the tibia after UKA. Conclusion. Postoperative posterior tibial slope reduced knee extension angle during one-leg standing after UKA. For any figures or tables, please contact authors directly

INTRODUCTION. Total knee arthroplasty (TKA) is an effective technique to treat end-stage osteoarthritis of the knee. One important goal of the procedure is to restore physiological knee kinematics. However, fluoroscopy studies have consistently shown abnormal knee kinematics after TKA, which may lead to suboptimal clinical outcomes. Posterior slope of the tibial component may significantly impact the knee kinematics after TKA. There is currently no consensus about the most appropriate slope. The goal of the present study was to analyze the impact of different prosthetic slopes on the kinematics of a PCL-preserving TKA. The tested hypothesis was that the knee kinematics will be different for all tested tibial slopes. MATERIAL. PCL-retaining TKAs (Optetrak Logic CR, Exactech, Gainesville, FL) were performed by fellowship trained orthopedic surgeons on six fresh frozen cadaver with healthy knees and intact PCL. The TKA was implanted using a computer-assisted surgical navigation system (ExactechGPS®, Blue-Ortho, Grenoble, FR). The implanted tibial baseplate was specially designed (figure 1) to allow modifying the posterior slope without repeatedly removing/assembling the tibial insert with varying posterior slopes, avoiding potential damages to the soft-tissue envelope. METHODS. Knee kinematics was evaluated by performing a passive range of motion (ROM) from full extension to at least 100 degrees of flexion. Passive ROM was repeated three times at each of the 4 posterior slopes selected: 10°, 7°, 4°, and 1° using the adjustable tibial component (figure 1). Respective 3D positioning of femur and tibia implants was recorded by the navigation system. Hip-knee-ankle (HKA) angle, femoro-tibial antero-posterior (AP) translation and internal-external (I/E) rotation were plotted according to the knee flexion angle. RESULTS. HKA angle (figure 2B): all 4 different tibial slopes induced a physiologic motion curve, and the kinematic differences between 10°, 7°, 4°, and 1° of posterior slope with the native knee were small. All slopes induced a varus angle beyond 60° of flexion, most likely was due to the external rotation of the femoral component. Femoro-tibial AP translation (figure 2C): all 4 different tibial slopes induced a physiologic motion curve and all slopes induced a large posterior translation before 80° of flexion, which was proportional to the slope. I/E rotation (figure 2A): all slopes induced an excessive internal rotation before 60° of flexion. DISCUSSION. A change in the tibial slope may impact significantly the TKA kinematics. Slopes of 1° and 4° seemed to be the better compromise with the specific implant used. Navigation systems are able to assess the knee kinematics after TKA. The test protocol has been assessed for reproducibility in a separate study with satisfactory results. Changing the tibial slope significantly impacted the TKA kinematics. With the specific implant used, rotational and coronal kinematics was only marginally impacted by the change in tibial slope. AP kinematics was significantly impacted by the change in tibial slope. These changes may be related to a change in the PCL strain. Slopes of 1° and 4° induced the more physiologic compromise

Total knee arthroplasty (TKA) is an effective technique to treat end-stage knee osteoarthritis, targeting the restore a physiological knee kinematics. However, studies have shown abnormal knee kinematics after TKA which may lead to suboptimal clinical outcomes. Posterior slope of the tibial component may significantly impact the knee kinematics. There is currently no consensus about the most appropriate slope. The goal of the present study was to analyse the impact of different prosthetic slopes on the kinematics of a PCL-preserving TKA, with the hypothesis that posterior slopes can alter the knee kinematics. A PCL-retaining TKA (Optetrak CR, Exactech, Gainesville, FL) was performed by a board-certified orthopaedic surgeon on one fresh frozen cadaver that had a non arthritic knee with an intact PCL. Intact knee kinematic was assessed using a computer-assisted orthopaedic surgery (CAOS) system (ExactechGPS®, Blue-Ortho, Grenoble, FR) Then, TKA components were implanted using the guidance of the CAOS system. The implanted tibial baseplate was specially designed to allow modifying the posterior slope without repeatedly removing/assembling the tibial insert with varying posterior slopes, avoiding potential damages to the soft-tissue envelope. Knee kinematic was evaluated by performing a passive range of motion 3 separate times at each of the 4 posterior slopes: 10°, 7°, 4° and 1°, and recorded by the navigation system. Femorotibial rotation, antero-posterior (AP) translation and hip-knee-ankle (HKA) angle were plotted with regard to the knee flexion angle. Tibial slopes of 1° and 4° significantly altered the normal rotational kinematics. Tibial slopes of 7° and 10° led to a kinematics close to the original native knee. All tibial slopes significantly altered the changes in HKA before 90° of knee flexion, without significant difference between the different slopes tested. The magnitude of change was small. There was no significant change in the AP kinematics between native knee and all tested tibial slopes. Changing the tibial slope significantly impacted the TKA kinematics. However, in the implant studied, only the rotational kinematics were significantly impacted by the change in tibial slope. Tibial slopes of 7° and 10° led rotational kinematics that were closest to that of a normal knee. Alterations in knee kinematics related to changing tibial slope may be related to a change in the PCL strain. However, these results must be confirmed by other tests involving more specimens

This study was designed to emphasise the need for strict rotational alignment whilst performing a posterior sloping tibial resection during primary TKR. The normal posterior inclination of the bony tibia in the sagittal plane is around 10 degrees. The effect of the menisci reduces this to around 3 degrees. This reduces shear stress during flexion when compressive stress increases. In TKR it has been shown that tibial components inserted with zero posterior slope (ie. perpendicular in the sagittal plane to long axis of tibia) have an increased incidence of anterior subsidence. This has been shown to be due to the relative weakness of the anterior tibial bone. It is also known that this weakness increases with further resection. Therefore, most knee arthroplasty systems involve a posterior sloping tibial resection to minimize anterior bone loss. This resection, normally in the order of 7 degrees, needs to be made strictly in the AP plane. If a rotational error is introduced, the result will be to remove more bone from one plateau than the other and effectively produce a valgus or varus deformity. If the long axis alignment of the jig is also inaccurate, this will compound the error. The authors, using a series of sawbones calculated the resultant varus/valgus angulation produced by different degrees of rotational malalignment using posterior sloped cutting blocks of 3 and 7 degrees. We plan to confirm these findings by using a 3 D CT reconstruction of the human proximal tibia and computer software to simulate the cuts. We have shown that a rotational error of 30 degrees with a 7 degree cutting block will produce an angulation of up to 3 degrees measured in the coronal plane. Whilst not large in itself, this potential error should be highlighted, as a contributive factor in tibial component malalignment

In PCL-retaining TKA, tension in the PCL is sensitive to changes in the posterior slope of the tibia component. However, it is not understood how PCL tension, in combination with the absence of the ACL, affects knee kinematics. This study demonstrates the effects of varying posterior tibial slope on the tibiofemoral and patello-femoral kinematics after PCL-retaining TKA. Eight fresh-frozen lower limb specimens were mounted in a kinematic knee simulator. External forces were applied to create a deep knee bend from 0–110 degrees of flexion, while the three-dimensional motions of the femur, patella and tibia were tracked in real time using a motion analysis system. A PCL-retaining TKA was implanted into each cadaver with the tibial component matching the natural posterior slope of the tibia. After testing, the tibial slope was reduced by four degrees compared to the natural slope, then increased by four degrees compared to the natural slope. With each change in slope, the kinematics of the knee were recorded. A dramatic change in femoral rollback was observed with increasing slope of the tibial component. In full extension, matching the natural tibial slope displaced the femur 5.7 ± 1.5 mm posteriorly, while more anterior slope and more posterior slope displaced the femur 5.1 ± 2.6 mm and 8.7 ± 2.0 mm posteriorly, respectively. Paradoxically, increased posterior slope resulted in less rollback of the femur during flexion. At 100° a of flexion, total rollback was 11.8 ± 2.6 mm in the intact knee, 6.9 ± 2.4 mm with the natural slope, 9.0 ± 2.8 mm with the anterior slope, and 5.7 ± 2.3 mm with the posterior slope. Preserving the PCL allows the femur to rollback on the tibial plateau with knee flexion. However, increasing the natural slope of the tibia causes a significant posterior shift of the femur in extension thus reducing rollback in flexion

Introduction. Pre-clinical assessment of total knee replacements (TKR) can provide useful information about the constraint provided by an implant, and therefore help the surgeon decide the most appropriate configurations. For example, increasing the posterior tibial slope is believed to delay impingement in deep flexion and thus increase the maximal flexion angle of the knee, however it is unclear what effect this has on anterior-posterior (AP) constraint. The current ASTM standard (F1223) for determining constraint gives little guidance on important factors such as medial- lateral (M:L) loading distribution, flexion angle or coupled secondary motions. Therefore, the aim of the study was to assess the sensitivity of the ASTM standard to these variations, and investigate how increasing the posterior tibial slope affects TKR constraint. Methods. Using a six degree of freedom testing rig, a cruciate-retaining TKR (Legion; Smith & Nephew) was tested for AP translational constraint. In both anterior and posterior directions, the tibial component was displaced until a ‘dislocation limit’ was reached (fig. 1), the point at which the force-displacement graph started to plateau (fig. 2). Compressive joint loads from 710 to 2000 N, and a range of medial-lateral (M:L) load distributions, from 70:30% to 30:70% M:L, were applied at different flexion angles with secondary motions unconstrained. The posterior slope of the tibial component was varied at 0°, 3°, 6° and 9°. Results. AP translation was significantly larger at 60° and 90° flexion (22 ± 1 mm and 24 ± 1 mm respectively) than at 0° (14 ± 1 mm), whilst increasing the compressive joint load increased the force required to translate the tibia to limits of AP constraint at all flexion angles tested. When the M:L load distribution was shifted medially, a coupled internal rotation was observed with anterior translation and external rotation with posterior translation; this was reversed with a lateral shift in load distribution. It was also found that increasing the posterior slope of the tibial tray moved the neutral position of the tibia relative to the femur more anteriorly at all flexion angles tested. The constraint under anterior drawer was then reduced with increasing slope, which meant that the tray dislocated at lower drawer force and translations. Conclusions. When intraoperative tibial bone cuts are made, surgeons should be aware that by increasing posterior slope angles the TKR may offer less anterior constraint under body-weight loads, therefore relying more heavily on surrounding soft-tissue and muscle action to prevent dislocation. The ASTM test protocol could be refined to stipulate the variation of the M:L loading distribution. It has been shown to vary between patients and activities, and the AP constraint and associated secondary motions in this study were very sensitive to this distribution. The secondary motions observed should be measured and recorded to provide more information about the device's stability characteristics. The tests could also be extended to include a higher axial load such as 2000 N, approximately three times body weight, in order to investigate coupled rotations and M:L distribution effects whilst under normal walking gait loads

Purpose:. A higher posterior tibial slope can potentially result in kinetic and kinematic changes of the knee. These changes may influence knee functionality in ACL-deficient and ACL-reconstructed subjects. The purpose of this study was to investigate the relationship between knee functionality and posterior tibial slope in ACL-deficient and ACL-reconstructed subjects. Methods:. Subjects with isolated ACL injuries and subjects who underwent ACL-reconstruction with bone-patella-bone-tendon (BPTP) between 18 and 24 months post surgery were included in the study. Posterior tibial slope was measured on a lateral radiograph using the posterior tibial cortex as a reference. The Cincinnati scoring system was used to assess knee functionality. Results:. 44 ACL-deficient patients with a mean age of 26.6 years and 24 ACL-reconstructed patients with a mean age of 27.2 (25–49) years were included. The posterior tibial slope in the ACL-deficient group averaged 6.10±3.57 degrees (range 0–17 degrees) and 7.20±4.49 degrees (range 0–17) in the ACL-reconstructed group. An anterior tibial slope was not measured in any of the participants. The mean Cincinnati score in the ACL-deficient subject was 62.0±14.5 and 89.3±9.5 in the ACL-reconstructed subject. There was a moderate but non-significant correlation (r=0.47) between knee functionality and slope in the ACL-deficient subject. Dividing posterior tibial slope into intervals, a strong significant correlation (r=0.91, p=0.01) was observed between knee functionality and slope. There was a weak but non-significant correlation (r=0.24) between knee functionality and slope in the ACL-reconstructed patient. Dividing posterior tibial slope into intervals (0–4, 5–9, >10) a strong and significant correlation (r=0.96, p=0.0001) was observed between knee functionality and slope. Conclusion:. The results of this study suggest that subjects with a higher posterior tibial slope have higher knee functionality. This is in contrast to previous research

A higher posterior tibial slope can potentially result in kinetic and kinematic changes of the knee. These changes may influence knee functionality in ACL-deficient and ACL-reconstructed subjects. The purpose of this study is to investigate the relationship between knee functionality and posterior tibial slope in ACL-deficient and ACL-reconstructed subjects. Subjects with isolated ACL injuries and subjects who underwent ACL- reconstruction with BPTP between 18 and 24 months post surgery were included in the study. Posterior tibial slope was measured on a lateral radiograph using the posterior tibial cortex as a reference. The Cincinnati scoring system was used to assess knee functionality. Frty-four ACL-deficient patients with a mean age of 26.6 years, and 44 ACL-reconstructed patients with a mean age of 27.2 (25–49) years were included. The posterior tibial slope in the ACL-deficient group averaged 6.10±3.57 degrees (range 0–17 degrees) and 7.20±4.49 degrees (range 0–17) in the ACL-reconstructed group. The mean Cincinnati score in the ACL-deficient subject was 62.0±14.5 and 89.3±9.5 in the ACL-reconstructed subject. There was a moderate but non-significant correlation (r=0.47) between knee functionality and slope in the ACL-deficient subject. By dividing posterior tibial slope into intervals, a strong significant correlation (r=0.91, p=0.01) was observed between knee functionality and slope. There was a weak but non-significant correlation (r=0.24) between knee functionality and slope in the ACL-reconstructed patient. Dividing posterior tibial slope into intervals (0-4, 5-9, >10) a strong and significant correlation (r=0.96, p=0.0001) was observed between knee functionality and slope. The results of this study suggest that subjects with a higher posterior tibial slope have higher knee functionality. This is in contrast to previous research

Aims. This study aims to investigate the effects of posterior tibial slope (PTS) on knee kinematics involved in the post-cam mechanism in bi-cruciate stabilized (BCS) total knee arthroplasty (TKA) using computer simulation. Methods. In total, 11 different PTS (0° to 10°) values were simulated to evaluate the effect of PTS on anterior post-cam contact conditions and knee kinematics in BCS TKA during weight-bearing stair climbing (from 86° to 6° of knee flexion). Knee kinematics were expressed as the lowest points of the medial and lateral femoral condyles on the surface of the tibial insert, and the anteroposterior translation of the femoral component relative to the tibial insert. Results. Anterior post-cam contact in BCS TKA was observed with the knee near full extension if PTS was 6° or more. BCS TKA showed a bicondylar roll forward movement from 86° to mid-flexion, and two different patterns from mid-flexion to knee extension: screw home movement without anterior post-cam contact and bicondylar roll forward movement after anterior post-cam contact. Knee kinematics in the simulation showed similar trends to the clinical in vivo data and were almost within the range of inter-specimen variability. Conclusion. Postoperative knee kinematics in BCS TKA differed according to PTS and anterior post-cam contact; in particular, anterior post-cam contact changed knee kinematics, which may affect the patient’s perception of the knee during activities. Cite this article: Bone Joint Res 2020;9(11):761–767

Aim. To assess the influence of posterior slope on Knee flexion and function in Asian and Caucasian populations. Material & methods. We have conducted a prospective comparative study of 109 Asian and Caucasian posterior tibial slopes. All data has been collected prospectively and includes personal data (height, weight, tibial measurements), ASA grading, knees scores and range of movement. Analysis was performed for the whole group and comparisons were made between the two sets of patients. Minimum follow-up was two years. Results and conclusion. Patients were well-matched for Age, Sex and ASA grading at time of surgery. The system for TKR we used aims for a slope of 5 degrees. The average posterior slope in Caucasian patients was 3.9 degrees pre-TKR and 4.55 degrees post-TKR. However in Asian patients the average slope was 10 degrees pre-TKR and 4.45 degrees post-TKR. We have analysed the significance of this change in Asian patients and compared this with data for range of movement and Knee score at a minimum of two years. The Asians tend to have greater pre-operative posterior slopes as compared to Caucasians. The changes in knee flexion, knee scores and knee functions (Knee Society Clinical Rating Systems Scores) in the two groups were not statistically significant. Although previous studies have shown that decreasing the posterior slope would reduce the range of flexion after TKR, our study has shown that posterior slope has no role in changes in knee flexion, knee scores and knee functions. We therefore feel that increased posterior tibial slope in Asian patients should not deter one from changing their practice of using normal tibial cuts as final post-operative results have no bearing on it

PURPOSE:. Unicompartmental knee arthroplasty (UKA) is becoming more commonly performed and is more technically challenging than total knee replacement. Retention of the anterior and posterior cruciate ligaments requires more accurate re-creation of the patient's normal anatomic posterior slope with UKA. Purpose of this study was to accurately determine the posterior tibial slope in patients having medial or lateral UKA performed. METHODS:. Retrospective review was performed of 2,395 CT scans performed for a customized UKA implant. Standard CT technique was used and the posterior slope was measured on the involved side of the proximal tibia. RESULTS:. CT measurements from 2031 knees undergoing medial UKAs had an average pre-operative posterior slope of 6.8 deg (SD 3.3), in these patients the posterior slope was between: 0–4 deg in 430 knees (21.2%), 4–7 deg in 696 knees (34.3%), 7–10 deg in 545 knees (26.8%), >10 deg in 360 knees (17.7%), and 13 knees (0.6%) had a reversed (anterior) tibial slope. Measurements from the 364 knees undergoing lateral UKAs showed an average pre-operative posterior slope of 8.0 deg (SD 3.3), in these patients the posterior slope was between: 0–4 deg in 43 knees (11.8%), 4–7 deg in 100 knees (27.5%), 7–10 deg in 118 knees (32.4%), >10 deg in 103 knees (28.3%), and 1 knee (0.3%) had a reversed (anterior) tibial slope. CONCLUSION:. There is marked variability in the posterior slope of the proximal tibial with 44.5% of medial plateaus and 60.7% of lateral plateaus having more than 7 deg of posterior slope pre-operatively. This is the first large CT based review of posterior slope variation of the proximal tibia. If attempting to match the patient's proximal slope during UKA, a routine setting of 5 degrees posterior slope will produce a posterior slope less than the patient's native anatomy in more than 50% of patients

Conventional proximal tibial osteotomy is a widely successful joint-preserving treatment for osteoarthritis; however, conventional procedures do not adequately control the posterior tibial slope (PTS). Alterations to PTS can affect knee instability, ligament tensioning, knee kinematics, muscle and joint contact forces as well as range of motion. This study primarily aimed to provide a comprehensive investigation of the variables influencing PTS during high tibial osteotomy using a 3D surgical simulation approach. Secondly, it aimed to provide a simple means of implementing the findings in future 3D pre-operative planning and /or clinically. The influence of two key variables: the gap opening angle and the hinge axis orientation on PTS was investigated using three independent approaches: (1) 3D computational simulation using CAD software to perform virtual osteotomy surgery and simulate the post-operative outcome. (2) Derivation of a closed-form mathematical solution using a generalised vector rotation approach (3) Clinical assessment of synthetically generated x-rays of osteoarthritis patients (n=28; REC reference: 17/HRA/0033, RD&E NHS, UK) for comparison against the theoretical/computational approaches. The results from the computational and analytical assessments agreed precisely. For three different opening angles (6°, 9° and 12°) and 7 different hinge axis orientations (from −30° to 30°), the results obtained were identical. A simple analytical solution for the change in PTS, ΔP. s,. based on the hinge axis angle, α, and the osteotomy opening angle, θ, was derived:. ΔP. s. =sin. -1. (sin α sin θ). The clinical assessment demonstrated that the absolute values of PTS, and changes resulting from various osteotomies, matched the results from the two relative prediction methods. This study has demonstrated that PTS is impacted by the hinge axis angle and the extent of the osteotomy opening angle and provided computational evidence and analytical formula for general use

Coronal alignment is an important factor in long-term survival of TKA. Many implant systems are available and most aim to produce a posterior slope on the tibial component to reproduce the 7. 0. seen in the normal tibia. We hypothesized that resecting the tibial plateau with a posterior slope can introduce error in coronal plane alignment in TKA. We used a standard saw-bones model in conjunction with a computer navigation system that is available for use in TKA (Stryker Orthopaedics). The normal protocol for preliminary referencing was followed; care was taken to identify tibial landmarks (tibial plateau reference point, true sagittal plane and transmalleolar axis). We then used a standard extramedullary alignment jig (Scorpio TKR System, Stryker Orthopaedics) with cutting blocks designed to give 0, 3, 5 and 7 degrees of posterior slope and varied the position of the alignment jig. Variations included:. Medial rotation of the cutting block,. Medialisation of the plateau reference point,. Mediolateral translation of the distal jig, and. External rotation of the distal jig. In all experiments, there was a greater deviation from ideal coronal alignment as the slope on the tibial cut was increased. The greatest influence was with external rotation of the distal part of the jig, which produced 3. 0. of varus at only 15. 0. of external rotation with a 7. 0. slope. Medialisation of the proximal reference point worsened this to 4.5. 0. of varus. We have quantified the degree of coronal malalignment that can occur for different posterior slopes during tibial resection for TKA. We recommend either using a minimal slope or navigation to ensure correct implant positioning. Correspondence should be addressed to Major M Butler RAMC, Princess Elizabeth Orthopaedic Centre, Royal Devon and Exeter Hospital, Exeter, Devon

Introduction. Optimal alignment of the tibial component in TKA is an important consideration. General agreement exists on the appropriate coronal alignment. However there is no consensus on sagittal alignment (posterior slope). Some surgeons target a fixed posterior slope (usually between 0 and 10 degrees), while others attempt to match the patient's intrinsic anatomy. The purpose of this study was to evaluate the tibial posterior slope in patients undergoing TKA. Methods. 13,586 CT scans of patients undergoing patient specific were analyzed. Three-dimensional reconstructions were performed and the posterior tibial slope was measured. Mean slope and ranges were determined. Results. Mean tibial posterior slope was 7.2 +/− 3.7 degrees (range −5 to 25 deg.) 35% of patients had tibial slope measurements more than 3 degrees different from the mean slope of this population. Conclusion. This study demonstrated a remarkable variability of tibial slope in patients undergoing TKA. This information may be useful to surgeons in determining “optimum” sagittal alignment of the tibial component for an individual patient. A patient with preoperative tibial slope very different from “average” may be at risk for sagittal malalignment of the tibial component. Additionally, large preoperative to postoperative changes in tibial slope may adversely affect knee kinematics and clinical outcome