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Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 460 - 460
1 Apr 2004
McCombe P
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Introduction: Surgical management of discogenic low back pain has in the past been limited to spinal fusion. Recently disc arthroplasty has become available. The rationale for disc arthroplasty is that it may avoid the long term consequences of adjacent segment degeneration. Avoidance of long term consequences is of no value unless the short term outcome is at least equivalent between fusion and arthroplasty. Methods: A series of patients with chronic low back pain with concordant lumbar discography and a negative control discogram were surgically treated. Prospective data was collected preoperatively and at regular intervals during the post-operative period for a historical series of combined anterior and posterior lumbar fusion (n =24), a series of SB Charité (DePuy Spine) disc replacements (n =23), and recently, a series of Maverick (Medtronic Sofamor Danek) artificial disc replacements (n =9). Self assessed outcome measures of visual analog pain score (VAS), Low Back Outcome Score (LBOS) and SF12 general health data was obtained at intervals after the surgery. This paper presents the results of the consecutive series that have a minimum of 3 months follow-up. Results: The data for the two groups of arthroplasty was combined and compared to the fusion group. The mean age for the fusion group was 37.6 years and the mean age for the arthroplasty group was 38.6 years. There were 5 compensation cases (20.8 %) in the fusion group and 5 cases (15.6 %) in the arthroplasty group. Both groups had 69% male patients. The mean VAS dropped from 7.5 to 3.7 (p< 0.001) in the arthroplasty group and from 7.3 to 3.5 (p< 0.001) in the fusion group. The mean LBOS improved from 22.0 to 36.5 (p< 0.001) in the arthroplasty group and from 19.6 to 37.1 (p< 0.001) in the fusion group. There was no apparent difference between the clinical improvement in VAS and LBOS (p=0.91 and p=0.45 respectively) for each group. Analysis of the power of the comparison showed an 86% power for comparison of VAS improvement using a clinically important difference (delta) of 1 VAS point and there was 98% power for the LBOS improvement comparison using a clinically important difference (delta) of 10 LBOS points. Complications appeared higher in the arthroplasty group with foraminal encroachment requiring revision in 3 cases and one case of polyethylene failure in the Charité group at 3 years. This case occurred with an 8mm polyethylene insert (since removed from inventory by the manufacturer). Discussion: Disc arthroplasty in the lumbar spine appears to offer similar short term results to that of fusion for chronic low back pain. The surgical complication rate may be higher in the early learning curve of the procedure


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_III | Pages 222 - 222
1 Mar 2003
Gaitanis I Tzermiadianos M Katonis P Thalassinos I Muffoletto A Hadjipavlou A
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Aim: Presentation of the application of the transcervical system of posterior spinal fusion Varigrip in spinal infections showing its rapid and safe application and also its stability to the spinal level where it is applied to.

Patients and Methods: 22 patients (13 men / 9 women) with mean age 50, 6 years (18–79) and mean follow up time is 34,6 months (9–62) were included in our study. In 10 patients the level was in lumbar spine and in 12 in thoracic spine. In their admission 16 patients had neurological deficit and 22 mean pain score according to VAS 8, 4 (6–10). ESR was increased in 14 patients, CRP in 20 and 7 patients had also increased WBC. All 22 patients had increased signal of Tc” and 69Ga in the level of the lesion and also pathological signal in MRI (Tl, T2 and Tl with Gadolinium). All the patients underwent posterior spinal fusion using Varigrip system and 17 of these underwent in the same time somatectomy and anterior fusion.

Results: Pathologic organism was isolated to all the patients. In 20 patients the tissue culture of the lesion isolated the pathologic organism and the other 2 patients came to us with positive blood cultures from other hospitals. 6 months postoperatively 21 patients referred pain score according to VAS 2,4 (1–4) and 1 patient had no improvement (5–7). 1 patient died of PE, another of chest infection and one of head injury. 1 patient had recurrence of the infection in another level, 1 had herpeszoster and 1 had infection of the surgical wound. All the patients had neurological improvement postoperatively.

Conclusions: The method is characterized as safe because of avoidance of the neurological structures. It can be applied also safely to patients with osteoporosis. Its application is rapid so the surgical time is minimum and also it doesn’t need image intensifier during the surgical procedure. It can be applied easily either in thoracic or lumbar spine and it provides stability of the spine.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 484 - 484
1 Sep 2009
Garrido E Noordeen H Tucker S
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Study Design: Retrospective study with clinical and radiological evaluation of 15 patients with congenital kyphosis or kyphoscoliosis who underwent anterior instrumented spinal fusion for posterolateral or posterior hemivertebae (HV).

Objective: To evaluate the safety and efficacy of early surgical anterior instrumented fusion with partial preservation of the HV in the treatment of progressive congenital kyphosis in children below the age of 3. We discuss the management of patients presenting with neurological compromise.

Summary of background data: A variety of treatments have been described in the literature for the treatment of congenital kyphosis due to HV. We report the results of our technique.

Materials and Methods: Between 1997 and 2005 we have treated 15 consecutive patients with progressive congenital kyphosis with anterior instrumented fusion and strut grafting. 13 patients had a single posterolateral HV and 2 patients a single posterior HV. Of the 15 patients in the study, 5 were girls and 10 boys. Mean age at surgery was 22 months (range 8–33). Mean follow-up period was 6.8 years. 13 HV were located in the thoracolumbar junction (T10-L2) and 2 in the thoracic spine.

Results: The average operating time was procedure was 150 minutes (range, 130 to 210 minutes). The average blood loss 180 mL (range, 100 to 330 mL), equivalent to a mean external blood volume loss of 15% (range, 11 to 24%).

Preoperative segmental Cobb angle averaging 34 º at last follow up. Compensatory coronal cranial and caudal curves corrected by 50%. The angle of segmental kyphosis averaged 39º (range, 20º to 80º) before surgery and 21 º (range, 11º to 40º) at last follow up. This represents a 43% of improvement of the segmental kyphosis, and a 64% of improvement of the segmental scoliosis at last followup.

One case with initial kyphosis of 80 º continued to progress and required revision anterior and posterior surgery. There were no neurologic complications.

Key points:

In progressive congenital kyphoisis, early diagnosis and aggressive surgical treatment are mandatory for a successful result.

Early treatment minimizes the risks of surgery.

Anatomical and physiological pitfalls in the treatment of congenital kyphosis are discussed.

Anterior instrumented fusion of congenital kyphosis provides sagital and coronal correction in very young children with low risk of complications.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_I | Pages - 13
1 Mar 2002
Bastian L Lange U Knop C Zdichavsky M Oeser M Blauth M
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The biomechanical effects on facet joints after posterior fusion remain unclear and seem to be responsible for accelerated degeneration. The following biomechanical study was performed to investigate the effects on the pressure and mobility of neighbouring unfused segments after double level T12-L2 posterior stabilization. The experimental study was performed on eighteen fresh, human, cadaveric thoracolumbal spine specimens. The specimens were cleaned and dissected from muscles and fat with care to preserve bone-ligament units intact. In a specially constructed testing machine the data of the segmental pressure and mobility of adjacent segments above and below the fusion were measured before and after double level T12-L2 posterior stabilization with an internal fixator (Universal Spine System) in flexion, extension, lateral bending, and rotation. For measuring the mobility a motion tracker (3Space Fastrak) and for direct evaluation of the pressure a quartz miniature force transducer was used. Also the bone mineral density of the specimens were measured and showed normal values. In flexion and extension Range of Motion (ROM) of the segment above the double level T12-L2 posterior fusion was significantly increased (p< 0,05). In the adjacent segment below the fusion there was no significant increased mobility after fusion for each moment was applied. The pressure did not show any significant difference, but after posterior fusion in flexion and extension the pressure below the posterior fusion (L2/L3) was decreased and above the fusion (T11/T12) increased. There is evidence that the adjacent segment above a double-level T12-L2 posterior fusion becomes more mobile and leads possibly to an accelerated degeneration in the facet joints due to increased stress at this point. Also the posterior fusion seems to change the load distribution in the facets of adjacent segments. These results could be responsible for symptoms like low back pain after spinal surgery


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 218 - 218
1 Mar 2010
Melloh M Aghayev E Zweig T Barz T Theis J
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Posterior lumbar fusion is one of the most frequent procedures in spinal surgery. This study examined which factors predict physician-based outcomes in posterior lumbar fusion within the international spine registry Spine Tango. This study used prospective consecutive hospital based documentation. Between May 2005 and October 2007 720 patients had been treated with posterior lumbar fusion for degenerative disease or spondylolisthesis. McNab criteria as commonly used physician-based outcomes were chosen as dependent outcome variable. We dichotomised the original McNab criteria combining “excellent” with “good” to “good”, and “fair” with “poor” to “poor”. Multivariate logistic regression was performed on following potential predictor-variables: age, gender, main pathology, number of previous spinal surgeries, number of spinal segments of posterior fusion, operation time, surgeon credentials, follow-up interval. Median age was 63 years (range 13–90 yrs) with a female to male ratio of 6.3:3.7. Number of previous spinal surgeries (p< 0.001) and follow-up interval (p< 0.001) were found to be predictors of the dichotomised McNab criteria. Patients without previous spinal surgery showed the highest ratio of “good” to “poor” outcome (80.5%:19.5%). This ratio was almost consistently decreasing with the number of previous spinal surgeries to 40%:60% in patients with more than five previous surgeries. At six and twelve-weeks follow-up outcomes were significantly better than after one year, without significant differences between other follow-up intervals. Other examined co-variables showed no influence on the outcomes. Predictors of physician-based outcomes in posterior lumbar fusion are “number of previous spinal surgeries” and “follow-up interval”. In patients with more than five previous spinal surgeries a higher likelihood of “poor” outcomes should be taken into consideration. A too positive outcome may occur at six or twelve-week’s follow-up


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 378 - 378
1 Jul 2011
Melloh M Zweig T Aghayev E Röder C Theis J
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Posterior lumbar fusion is a frequently performed procedure in spinal surgery. High percentages of good and excellent results are indicated by physicians. On the other hand patient-based outcomes are reported. Little is known about the correlations of these two assessment types. We aimed at their comparison. The analysis included 1013 patients with degenerative spinal disease or spondylolisthesis from an international spine registry, treated with posterior lumbar fusion. All patients were pre/postop assessed by physician-based McNab criteria (‘excellent’, ‘good’, ‘fair’, ‘poor’). Of these patients, 210 (mean age 61 years; 57% females) were in addition assessed by patient-based Oswestry Disability Index (ODI). The remaining 803 patients (mean age 59 years; 56% females) were assessed by patient-based Core Outcome Measure Index (COMI), including. Visual Analogue Scale (VAS) for back and leg pain as well as verbal self-rating (‘helped a lot’, ‘helped’, ‘helped only little’, ‘didn’t help’, ‘made things worse’). McNab criteria were compared to the Minimal Clinically Important Difference (MCID) in ODI (12.8), in VAS back (1.2) and leg pain (1.6). We investigated the correlations between McNab criteria and these patient-based outcomes. In the ‘excellent’ group as rated by physicians, the proposed MCID was reached in 83% of patients for ODI, in 69% for VAS back and in 83% for VAS leg pain. All patients said the treatment had ‘helped’ or ‘helped a lot’. In the ‘good’ group 56% (ODI), 66% (back pain) and 86% (leg pain) reached the MCID. 96% of patients perceived the treatment as positive. In the ‘fair’ group 37% (ODI), 55% (back pain) and 63% (leg pain) reached the MCID. 49% had positive treatment considerations. The ‘poor’ group revealed 30% (ODI), 35% (back pain) and 44% (leg pain) of patients with reached MCID. Only 15% rated the treatment as positive. The Spearman correlation coefficients between McNab criteria on the one hand and ODI, back and leg pain as well as patients’ verbal self-rating on the other hand were 0.57, 0.37, 0.36 and 0.46 respectively. The comparison of physician and patient-based outcomes showed the highest correlations between McNab criteria and ODI, somewhat weaker correlations with patients’ self-rating and the weakest correlations with back and leg pain. Based on these findings, physicians’ evaluation of patient outcomes can be considered a valuable part of patient assessment, corresponding very well with patients’ perceptions of success or failure of spinal surgery


Summary: Radiographic and clinical outcomes of anterior thoraco-lumbar and posterior instrumented spinal fusion in patients with double major (AIS) curves are evaluated in this retrospective study. The average thoracic curve was 68 degrees before surgery and 29.2 degrees at follow-up (mean correction 58.3%). The average preoperative lumbar curve was 73 degrees, decreasing to 18 degrees postoperatively (mean correction 77.5%). Instrumented anterior lumbar fusion followed by posterior instrumented fusion is a successful technique with low morbidity in AIS with double curve pattern. Introduction: Options exist for the surgical treatment of double major AIS curves. With the introduction of multi-level pedicle screw fixation in the thoracic and lumbar spines the role of anterior surgery is being questioned. This series demonstrates the results obtained by anterior thoraco-lumbar and posterior instrumented spinal fusion. Methods: 28 patients with double major curves who underwent anterior spinal release and instrumented fusion, with staged posterior instrumented spinal fusion between 1999 and 2005 were included for analysis. The minimum follow-up was 2 years after surgery (mean, 5 years; range, 2–8 years). The mean age of patients was 17,3 years (range, 13–21 years). Multiple radiographic parameters were assessed. Results: Successful selective thoraco-lumbar instrumented fusion and posterior instrumented fusion was performed in 28 consecutive patients with adolescent idiopathic scoliosis. The average thoracic curve was 68 degrees before surgery and 29,2 degrees at final follow-up (mean correction 58,3%). The average pre-operative lumbar curve was 73 degrees, decreasing to 18 degrees postoperatively (mean correction 77,5%), with good coronal and sagittal balance achieved. Tilt of the lower instrumented vertebra (LIV) improved from 28.2 degrees to 4.6 degrees on last follow-up. Disc angulation below the LIV averaged 6.1 degrees preoperatively and 3.6 degrees on last follow-up. Translation of the LIV from the center sacral vertical line averaged 34.5 mm preoperatively and 13.6 mm on last follow-up. Discussion: Instrumented anterior lumbar fusion followed by posterior instrumented fusion is a successful technique in adolescent idiopathic scoliosis with double curve pattern. These results show that this technique is able to restore normal coronal alignment of the distal unfused lumbar segment and saves fusion levels compared to posterior instrumentation only. Despite the extensive surgery, there is a very low morbidity in this population, with no evidence of pseudarthrosis. Significance: This represents a large unique series of patients treated for double major curve pattern in adolescent idiopathic scoliosis with low morbidity and excellent balanced corrections in both coronal and sagital planes


Study Design: Compartative cohort study. Objective: To compare the safety and efficacy of conventional posterior instrumented fusion versus thoracoscopic instrumented fusion for the surgical treatment of King Type III adolescent idiopathic scoliosis. Methods: The results of 34 consecutive patients with King type 3 scoliosis treated with one of the above techniques were analyzed independantly. Twenty-two patients underwent posterior spinal fusion (PSF) and instrumentation (Moss-Miami). Twelve patients had thoracoscopic fusion (TF) and instrumentation (Eclipse). Results: Baseline demographics (age at menarche and surgery, pre-operative Cobb angles in coronal and sagittal planes), estimated blood loss at surgery and duration of parenteral analgesia did not differ between the two groups. PSF patients had significantly higher transfusion requirements (p=0.032). Operative time (p = 0.0001), ICU stay (p = 0.005), and hospital stay (p = 0.037) were longer in TF cases. There were no complications in PSF patients. Complications in TF patients included lobar collapse (1 patient) and scapula winging (1 patient). Improvement in scoliosis among PSF patients averaged 75% (1 week), 70% (6 months), and 65% (1 year). In TF patients, mean improvement in scoliosis was 66% (1 week), 62% (6 months), and 62% (1 year). The differences between the two groups in terms of scoliosis improvement were not significant. Curves with apex at T8 or higher had better correction of scoliosis (p = 0.05). The sagittal alignment (thoracic kyphosis and lumbar lordosis) after surgery was similar between the two groups at 1 week, 6 months, and 1 year post-operatively. Conclusion: The efficacy of thoracoscopic anterior fusion and instrumentation is similar to standard posterior instrumented fusion. The advantages of the thoracoscopic technique are the avoidance of a long posterior midline scar, and lower transfusion requirement. A longer operative time, ICU and hospital stay was attributed to the steep learning curve of this endoscopic technique


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_6 | Pages 7 - 7
1 Apr 2014
Stedman T Smith L Cole A Breakwell L Michael A Naylor B
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Aim:. To Determine The Effect Of Posterior Instrumented Fusion On Lung Function In Patients With Idiopathic Scoliosis Aged 8–11. Method:. Lung Function (Fvc And Fev1) Was Measured Before Surgery In 13 Patients (Aged 8 To 11) With Idiopathic Scoliosis. All Patients Had Curves Greater Than 50 And Had Undergone Posterior Instrumented Scoliosis Correction And Fusion With (3 Patients) Or Without (10 Patients) Same Day Anterior Convex Growth Arrest. Lung Function Tests Were Repeated 1–8 Years (Mean 5.3 Years) After Surgery. The Data Was Normalised To Take Into Account Standing Height And Loss Of Stature Due To Lateral Curvature, Allowing A Direct Comparison Of Percent Predicted Fev1 And Fvc Before And After Surgery. Results:. Mean Fvc Was 75% Before Surgery And 79% At Longest Follow-Up (1.9l To 2.7l). Mean Fev1 Was 73% Before Surgery And 76% At Longest Follow-Up (1.7 To 2.4). The Change In Lung Function After Surgery Did Not Correlate With Length Of Time To Longest Follow-Up. The Ratio Of Fev1 To Fvc Was 0.86 Before And After Surgery. Discussion:. In Idiopathic Scoliosis Below The Age Of 8 Years, Most Would Accept That Instrumentation Should Allow Spinal Growth To Try And Maintain Lung Function. Above The Age Of 11, Lung Function Is Probably Sufficient To Allow Instrumented Fusion With Its Reduced Complication Rate And Reduced Need For Further Surgery. Between The Ages Of 8 And 11 Controversy Exists. This Pilot Study Suggests That A Larger (Possibly Rct) Study Should Be Performed To Evaluate This Group Of Patients As Fusion May Be Appropriate As Percent Lung Function Corrected For Loss Of Height Due To Curvature Appears To Be Maintained. Conflict Of Interest Statement: No conflict of interest


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 613 - 613
1 Oct 2010
Zweig T Aebi M Aghayev E Melloh M Röder C Sobottke R Staub L
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Introduction: Posterior lumbar fusion, in many variations, is one of the frequently performed procedures in spinal surgery. High percentages of good and excellent results are indicated by physicians. On the other hand isolated patient-based outcomes are reported. However, little is known about correlation of these two assessment types. We aimed at their comparison. Methods: The analysis included 567 patients from the international registry ‘Spine Tango’. 453 patients with degenerative disease and posterior lumbar fusion had preop and postop VAS separately indicating back- and leg-pain, surgery and follow up data. Mean age was 57y; female/male ratio was 52% to 48%. Remaining 114 patients with the same diagnoses and treatment had additional preop and postop Oswestry disability indices (ODI). Mean age was 61y; female/male ratio was 55% to 45%. Physician administered McNab criteria “excellent, good, fair and poor” were compared to ODI, VAS back- and leg pain and to the patients answer describing the outcome of the operation with the following options: helped a lot, helped, helped only little, didn’t help and made things worse. Then the concept of minimum clinically important difference (MCID) was applied. Results: In the “excellent” group ODI-improvement was detected for all patients, the proposed MCID was reached in 90% for ODI. According to this model 85.2% of patients reached MCID for VAS leg pain and 54.1% for VAS back pain. All patient said that the treatment helped or helped a lot. In the “good” group 86% (MCID: 51.7%) of patients improved regarding ODI, 81% (MCID: 65,7%) regarding back and 93% (MCID: 89.4%) regarding leg pain. 99% of patients said that the treatment helped a lot, helped or helped only little. 65% (MCID: 40%) of patients in the “fair” group had improved ODIs. Even in this group 88% of patients perceived the treatment as helping a lot, helping or helping only little. Moreover in the “poor” group had 60% (MCID: 40%) of patients improved ODIs, 55% (MCID: 40%) alleviated back and 36% (MCID: 30%) reduced leg pain. But only 30% of patient stated that the treatment helped or helped only little. Spearman correlation coefficients for ODI, VAS back, VAS leg and patient’s verbal statement on overall outcome were 0.42, 0.18, 0.27 and 0.53. Discussion: ‘Spine Tango’ registry, to date containing more than 13.000 documented surgeries and three times more outcome datasets, provides excellent opportunities for comparison of outcomes. The analysis of patient and physician-based outcomes showed good correlation with the highest correlation coefficient for patient’s verbal statement. With this study we can state that there is strong evidence that physicians evaluation of outcome is very good corresponding with the patients’ perception of success or failure of the analyzed procedure


Introduction and Objective

Posterior and transforaminal lumbar interbody fusion (PLIF, TLIF) represent the most popular techniques in performing an interbody fusion amongst spine surgeons. Pseudarthrosis, cage migration, subsidence or infection can occur, with subsequent failed surgery, persistent pain and patient’ bad quality of life. The goal of revision fusion surgery is to correct any previous technical errors avoiding surgical complications. The most safe and effective way is to choose a naive approach to the disc. Therefore, the anterior approach represents a suitable technique as a salvage operation. The aim of this study is to underline the technical advantages of the anterior retroperitoneal approach as a salvage procedure in failed PLIF/TLIF analyzing a series of 32 consecutive patients.

Materials and Methods

We performed a retrospective analysis of patients’ data in patients who underwent ALIF as a salvage procedure after failed PLIF/TLIF between April 2014 to December 2019. We recorded all peri-operative data. In all patients the index level was exposed with a minimally invasive anterior retroperitoneal approach.


Objectives: The aim of this study was to determine the outcome of posterior lumbar interbody fusion using an intrasegmental pedicle screw device in a series of patients with symptomatic spondylolisthesis. Design: Prospective Case Series. Subjects: 34 consecutive patients underwent posterior lumbar fusion for symptomatic spondylolisthesis using an intrasegmental pedicle screw device between December 1998 and January 2002. The mean age was 48.6 (range 27–84) and 16 were male and 18 female. 22 patients had a spondylolisthesis at the L5/S1 level, 10 at the L4/5 level, 1 at the L3/4 level, 1 at the L2/3 level. 17 patients had a grade 1 slip, 16 grade 2, and 1 grade 3. 22 patients had a single intervertebral level fused, 10 two levels and 2 three levels. Outcome Measures: Fusion status was assessed using radiographs (lateral, AP and in the plain if the intervertebral disc). To be judged as fused, there had to be an absence of metalwork failure, pedicle screw loosening and fusion at all levels if a multi-level fusion. Patient outcome was assessed by means of a visual analogue scale (VAS) for pain, SF36 health assessment questionnaire, a patient subjective outcome assessment, employment status and analgesic usage. Results: Fusion was successfully achieved in 33 (97%) patients. The mean VAS reduced by 3.2 points from 8.3 to 5.1 (p=0.0001). There was a significant improvement in all the physical component scores of the SF36. The subjective outcome was either excellent or good in 24 (71%) patients. Of the 26 patients working prior to surgery, 20 (77%) returned to work. Analgesia usage reduced in 21 (61%) patients. One patient died in the post operative period. Conclusions: Our study supports the view that good clinical outcomes can be achieved by posterior interbody fusion of symptomatic spondylolisthesis. This particular intrasegmental device enables a safe, simple technique for reduction and fusion of symptomatic spondylolisthesis


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 271 - 271
1 Jul 2011
Marion TE Zeng Y Wai E
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Purpose: Perispinal core muscle strength has been theorized to be an important component in the pathogenesis of back pain. Recent research has demonstrated a strong association between preoperative perispinal musculature, adjusted for fatty infiltration and prospective outcomes and improvements in back pain in patients undergoing lumbar laminectomy without fusion. The purpose of this study is to determine if a similar relationship exists in patients undergoing elective posterior lumbar fusion and decompression (PLFD) surgery. Method: A retrospective observational study of prospectively collected outcomes data was conducted in which pre-operative function and patient variables of those undergoing PLFD were derived from a functional status questionnaire and medical records. ImageJ Digital Imaging Software was utilized to measure the total (CSA) and percentage of fatty infiltration of the psoas, multifidus, and erector spinae muscles in pre-operative L4 axial CT images. Pre-operative and post-operative lateral images were evaluated for degree of post-operative adjacent level degeneration. Follow-up consisted of a functional status questionnaire. Outcomes measured were improvements in back pain, leg pain, and Oswestry disability scores. Results: Twenty-three patients were analyzed with a mean follow-up of 2 years (range 1 – 5 years). Outcomes improved following surgery. There were strong to moderate correlations between percentage of fat in the pre-operative posterior spinal muscles and improvements in leg pain (r = 0.63, p = < 0.001) and improvements in back pain (r = 0.41, p = 0.05). There was a moderate trend towards greater adjacent level degeneration (r = 0.37, p = 0.1) in patients with higher percentage of fat in the pre-operative posterior spinal muscles. There was a strong relationship between greater adjacent level degeneration and pre-operative disability as measured by the Oswestry (r = 0.62, p = 0.03). Conclusion: The results demonstrate that a potential relationship exists between pre-operative fatty infiltration of posterior perispinal muscles and post-operative outcomes, and adjacent level degeneration following lumbar fusion surgery. This suggests that perispinal muscle atrophy and conditioning may play a role in these outcomes. Results may be used for prognostication, surgical candidate selection, and interventional strategies


Posterior instrumented fusion is an established surgical treatment for majority of AIS cases. In the past decade, thoracoscopic instrumentation and fusion has emerged as a viable alternative to conventional posterior techniques in situations that require selective thoracic fusion. Most reports comparing the two techniques have focused on physician-based outcomes such as curve correction and maintenance of the surgical correction with both methods being comparable. Recently, the SRS-24 has been used to evaluate patient-based outcomes after scoliosis surgery. The instrument assesses seven equally-weighted domains that look at pain, self-image, general function, activity level, change in self-image and function post-surgery, and satisfaction with the procedure. It has been used to evaluate differences between AIS and normal patients, and in different degrees of AIS deformity. The instrument has not been used in comparing different methods of surgical treatment for similar curve types. We applied the SRS-24 prospectively to our patients who had undergone either thoracoscopic (TG) or posterior (PG) instrumented fusion, and had been followed-up for at least 12-months postoperatively. There were 42 patients in TG and 42 patients in PG. The mean age at time of surgery, pre-operative Cobb angles, and number of spinal segments fused were similar in both groups. The mean follow-up period at the time the SRS instrument was administered was 26 (± 13.5) months for TG and 30.7 (± 12.1) months for PG. The postoperative Cobb angle on the latest follow-up was significantly better for TG compared to PG (17 versus 25.1 degrees, respectively; p < .001). Upon comparing the SRS domain scores between both groups, a significant difference was noted only in the patient satisfaction domain with TG scoring better than PG (p < .02). The first four SRS-24 domain scores for TG and PG were also compared to the corresponding domain scores of 97 patients who had scoliosis but were not candidates for surgery (SG), as well as to the scores of 72 patients who did not have scoliosis (NG). SG, TG, and PG were comparable with regards to pain and all three were significantly lower compared to NG (F=14.828, p < .0001). General function and activity level scores of TG were significantly lower compared to the other three groups (F=4.870, p < .003 and F=4.793, p < .003, respectively). Despite this, the self-image domain scores of both TG and PG were not significantly different from NG, with SG scoring significantly poorer compared to the other three groups (F=3.183, p < .02). In summary, thoracoscopic instrumented fusion resulted in better curve correction compared to posterior instrumented fusion and was achieved with less spinal segments being fused. This was despite the finding that patients who underwent thoracoscopic surgery had lower physical function and activity level scores. Additionally, both surgical techniques resulted in patients whose perception of themselves was comparable to those patients who did not have scoliosis. The SRS-24 was not able to detect any differences between the two surgical methods in all domains except for overall patient satisfaction which was significantly better in the thoracoscopic group


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 294 - 294
1 Sep 2005
Crawford R Crawford J Hilton J
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Introduction and Aims: Surgery for degenerative lumbar spondylolisthesis may entail both decompression and fusion. The knee-chest position facilitates decompression, but fixation in this position risks fusion in kyphosis. This can be avoided by intra-operative re-positioning to the fully prone position. We aim to quantify restoration of lordosis achieved by this manoeuvre.

Method: Thirty-six patients with degenerative lumbar spondylolisthesis and stenosis were treated by posterior decompression and interbody fusion with pedicle screw fixation (without interbody cages). There were 16 men and 20 women with a mean age of 58.2 years (32–80). The decompression, interbody grafting and screw insertion were performed with the patient in the knee-chest position. The patient was repositioned to the fully prone position for subsequent fusion. The sagittal plane angle was measured on the pre-operative, intra-operative and post-operative x-rays. Short-Form 36 (SF-36) scores and Visual Analogue Scales (VAS) for pain (0 to 10) were determined pre- and post-operatively.

Results: Twenty-eight patients underwent single-level fusion, two patients had two levels, two patients had three levels and four patients had four levels fused. The mean pre-operative sagittal angle between the operated vertebrae was 15.7 degrees lordosis, and the intra-operative angle before re-positioning was 14.9 degrees. The mean immediate post-operative angle was 23.7, and at six-month follow-up the angle was 23.1. Overall there was a mean increase in lordosis angle after repositioning of 8.0 degrees per operative level (p< 0.01). The mean scores of the SF-36 improved in all eight domains and this was significant (p< 0.05) for social functioning (44.4 to 68.9), energy and vitality (36.0 to 49.5), pain (23.8 to 58.3) and general health perception (51.4 to 65.6). Mean VAS pain scores for back pain improved from 7.47 pre-operatively to 3.84 post-operatively (p< 0.001); and for leg pain improved from 7.56 to 3.78 (p< 0.001). No complications attributable to the manoeuvre occurred.

Conclusion: Lumbar spondylolisthesis was found to be associated with reduction of normal lumbar lordosis. The knee-chest position for surgery exacerbates this loss of lordosis. Intra-operative repositioning restores lordosis to greater than the pre-operative angle, which may improve clinical outcome.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 325 - 325
1 May 2006
Martínez-Arribas E Sánchez-Ramos V Maroñas-Abuelo C Diaz-Fernandez R Bas T Bas P
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Purpose: To review the sagittal lumbar and clinical profile of the two surgical procedures: TLIF (transforaminal lumbar interbody fusion and ALIF (anterior lumbar interbody fusion).

Materials and methods: We carried out a retrospective study of 46 patients who underwent circumferential fusion in 2000–2001. TLIF was used in the first group (21) and ALIF in the second (25). The posterior approach with pedicle instrumentation was used in all patients. Lateral radiographs of the lumbar spine in neutral position and bipedestation were used for evaluation before and after surgery and during follow-up. The results were compared statistically using the Wilcoxon matched pairs test.

Results: Lumbar lordosis was achieved with both techniques: TLIF+PF(posterior fusion) −33° (preoperative), −46° (postoperative) and ALIF+ PF −49° (preoperative), −54° (postoperative). However the height of the disc improved significantly with the anterior approach: TLIF+ PF 0.62 (preoperative), 1.35 (postoperative) and ALIF+PF 1 (preoperative), 4.65 (postoperative).

The duration of surgery, blood loss and hospital stay were greater with ALIF+PF than with TLIF+PF.

Conclusions: TLIF+PF has clinical and economic advantages over ALIF+PF. Lumbar lordosis and the area of instrumented lordosis was achieved with both circumferential fusion procedures and the only radiographic difference was the restoration of the disc height with ALIF.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_14 | Pages 41 - 41
1 Dec 2022
Konstantinos M Leggi L Ciani G Scarale A Boriani L Vommaro F Brodano GB Gasbarrini A
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Recently, there is ongoing evidence regarding rapid recovery after orthopaedic surgery, with advantages for the patient relative to post operative pain, complications and functional recovery. The aim of this study is to present our experience in rapid recovery for adolescent idiopathic scoliosis in the last 2 years. Retrospective study of 36 patients with adolescent idiopathic scoliosis, (age range 11 to 18 years) treated with spinal thoraco-lumbar posterior fusion with rapid post-operative recovery, compared with a similar group, treated with traditional protocol. We found a statistically significant difference in terms of length-of-stay, patient-controlled-analgesia and use of oppioid and post operative blood transfusions. There was no difference in post operative infection rate. Our experience shows better functional recovery, satisfactory controlled analgesia and reduction in costs of hospitalization with the use of ERAS protocols


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_13 | Pages 18 - 18
1 Dec 2022
Singh S Miyanji F
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The routine use of intraoperative vancomycin powder to prevent postoperative wound infections has not been borne out in the literature in the pediatric spine population. The goal of this study is to determine the impact of vancomycin powder on postoperative wound infection rates and determine its potential impact on microbiology. A retrospective analysis of the Harms Study Group database of 1269 adolescent idiopathic scoliosis patients was performed. Patients that underwent a posterior fusion from 2004-2018 were analyzed. A comparative analysis of postoperative infection rates was done between patients that received vancomycin powder to those who did not. Statistical significance was determined using Chi-squared test. Additionally, the microbiology of infected patients was examined. In total, 765 patients in the vancomycin group (VG) were compared to 504 patients in the non-vancomycin group (NVG). NVG had a significantly higher rate of deep wound infection (p<0.0001) and associated reoperation rate compared to VG (p<0.0001). Both groups were compared for age, gender, race, weight, surgical time, blood loss, number of levels instrumented, and preop curve magnitude. There were significant differences between the groups for race (p<0.0001); surgical time (p=0.0033), and blood loss (p=0.0021). In terms of microbiology, VG grew p.acnes (n=2), and serratia (n=1), whereas NVG grew p.acnes (n=1) and gram positive bacilli (n=1). The remaining cultures were negative. The use of intraoperative vancomycin powder in adolescent idiopathic scoliosis appears to contribute significantly to deep wound infection prevention and reduction of associated reoperations. Based on this study's limited culture data, Vancomycin does not seem to alter the microbiology of deep wound infections


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_7 | Pages 15 - 15
8 May 2024
Coetzee C Myerson M Anderson J McGaver RS
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Introduction. AlloStem/Cellular Bone Allograft and autologous bone graft are accepted methods for managing hindfoot degenerative arthritis. The purpose was to evaluate outcomes of AlloStem and autograft in subtalar arthrodesis and compare overall fusion rates. Methods. This study was conducted in IRB compliance. Patients between 18–80 years who qualified for a subtalar fusion were randomized 1:1 to AlloStem or autologous graft. The AOFAS hindfoot ankle scale, FFI-R and SF-12 were collected pre-operatively, 6 weeks, 3 & 6 months, 1 and 2 year. Weight-bearing 3-view ankle X-rays were done at the same intervals. A CT scan was obtained at 6 months. Results. 140 patients were enrolled; 124 patients had surgery(60-AlloStem and 64-Control). Withdrawals included 14 voluntarily before surgery and 2 intra-operative failures. 19 were lost to follow-up. Mean age for AlloStem was 56.69(20.3–79.6) and Autograft was 54.60(20.74–80.07). 59 AlloStem patients completed their 6 month visit and 45 completed 2 years. AOFAS score improved: 40.02 at pre-op to 72.16(6 mo) to 79.51 at 1 year and 80.38 at 2 year. SF-12 improved 58.29 at pre-op to 65.67 at 6 month and 71.59 at 2 year. FFI-R improved 236.88 at pre-op to 203.53 at 6 month 149.93 at 2 year.60 Autograft patients completed their 6 month visit and 51 patients completed their 2 year. AOFAS score improved 42.89 at pre-op to 75.67 (6 mo) to 79.75 at 1 year and 78.62 at 2 year. Autograft SF-12 improved 60.55 at pre-op to 70.40 at 6 month and 75.26 at 2 year. Autograft FFI-R improved 217.16 at pre-op to 166.77 at 6 month and 145.43 at 2 year. AlloStem patients had a mean posterior fusion rate of 28.9% at 6 months whereas the Autograft had 46.3%(p=.049). Non-union rates were AlloStem(9/57)(15.7%) whereas Autograft was 3/60(5%). Conclusion. AlloStem trended to be inferior to Autologous graft


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_11 | Pages 11 - 11
1 Sep 2021
Abdullahi H Fenner C Ajayi B Fragkakis EM Lupu C Bishop T Bernard J Lui DF
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Introduction. Scoliosis surgery is a life-changing procedure, but not devoid of perioperative complications. Often patients' scoring systems do not cover their real-life needs, including return to pre-surgery activity. Return to school, physical education (PE) is an important indirect marker of recovery. Although anterior spinal fusion (ASF) may have advantages, compared to posterior spinal fusion (PSF), because of motion-saved segments, there is a paucity of literature about post-operative return to school/PE in the compared groups. Aim. To determine the recovery time for patients with scoliosis who underwent anterior spinal fusion (ASF) and posterior spinal fusion (PSF). Design. Prospective cohort. Methods. Patients undergoing Adolescent Idiopathic Scoliosis (AIS) surgery from 2018–2019, were examined. We excluded no-AIS and over 18y patients. The Scoliosis Sports Survey validated questionnaire was administered post-operatively regarding return to school, PE and other physical activities. ASF and PSF groups were subcategorised into: Selective Anterior Thoracic Fusion (SATF), Thoracolumbar Fusion (TLF), Short Posterior Spinal Fusion (SPSF) and Long Posterior Spinal Fusion (LPSF) procedures. Hospital length of stay (HLOS) and ICU LOS were recorded. Results. A total of 81 patients were contacted and 43 responded to the survey. The different procedures, return to school / PE, HLOS / ICU LOS, costoplasty are all analysed as shown below in Table 1. Conclusions. Anterior and posterior fusions had similar return to school rates at 1–3 months. The TLF and 2-stages groups returned to school the quickest, whilst the SATF had the longest return time. PSF patients returned to PE faster than ASF. Costoplasty, did not affect return time to school and PE. Further research assessing shorter fusions benefits should be conducted. For any figures or tables, please contact the authors directly