Introduction. We report the functional outcome and survivorship of the Hintegra Total Ankle Replacement (TAR), in consecutive cases by multiple surgeons in a single UK institution. Between 2010–2014 the Hintegra TAR held 7.1% UK market share and surgeons should be aware of failure mechanisms. Methods. We conducted a retrospective review of prospectively collected data for 70 consecutive Hintegra TAR cases in a single institution between 2010–2014. Data collected included patient demographics, complications, reoperations, patient reported outcome measures (PROMS: AOS, MOX-FQ, pain VAS) and patient satisfaction. Results. The 70 patients (54 male/ 16 female) had an average age of 69 (range 48–84 years). Mean follow up was 76 months (range 60–04), 10 patients died during the follow up. Implant survivorship was 81.4% at most recent follow up. The commonest radiographic finding was periprosthetic cysts (n=28, 40%), size range (7–40mm), location of cysts: isolated talus (n=14), isolated tibia (n=6), mixed (n=8). 10 failed TARs were revised to Inbone TAR at a mean of 48 months (range 9–69). 3 Failed TARs were revised to arthrodesis (2 tibiotalar fusions, 1 hindfoot nail). 11 patients required reoperation with implant retention: 8 periprosthetic cyst debridement and grafting at a mean of 61 months (range 27–91), 1 lateral gutter debridement and 1 periprosthetic fracture ORIF. PROMS data was available for all patients. Overall patients showed marked improvement in functional outcome scores between pre-operative and final follow up questionnaires. Mean pre-op AOS: 62, MOX-FQ: 68 and pain VAS: 67.5 with mean final follow up scores of: AOS: 35, MOX-FQ: 36 and pain VAS: 30. Conclusion. Our experience demonstrates improved PROMS following ankle arthroplasty for patients with a mean follow up of 6.4 years. Implant survivorship is similar to other TAR studies. We have identified a high incidence of periprosthetic cysts and would recommend ongoing surveillance of these patients

Aims: The aim of this study was to clinically and radiologically assess the outcome of the HINTEGRA total ankle prosthesis. The HINTEGRA implant is an uncemented (hydroxyapatite-coated) prosthesis of anatomical, multiaxial, congruent and unconstrained design. Methods: All of the consecutive 19 patients who got a HINTEGRA total ankle replacement between June 2000 and June 2001 were assessed. Pre- and postoperative functional and clinical assessment was carried out using a questionnaire, range of motion and Kofoed score which assigns 50 points for pain, 30 for function and 20 for range of motion, giving a maximum of 100. Results: 19 patients (6 female, 13 male), mean age 55,3 years (21–82 years), mean followup 14,3 months (10–21 months). The general satisfaction at subjective evaluation was 27,3/100 preoperatively and 80/100 postoperatively. The mean Kofoed score was 26,3 preoperatively and 78,4 postoperatively. The mean range of motion from maximum extension to maximum ßexion was 16,4¡ preoperatively and 29,1¡ postoperatively. None of the replacements showed any progressive radiolucency, although in 3 patients there was a small area (< 2mm) of radiolucency between the tibial component and bone. Conclusions: Our results with the uncemented HINTEGRA, anatomical shaped threecomponent total ankle replacement, are satisfactory and encouraging. Total ankle replacement is a useful alternative to ankle arthrodesis with pain relief and preservation of joint motion and stability

The purpose of this study was to obtain anatomical measurements of the distal tibia and talus of Korean ankles and to evaluate, based on those measurements, the compatibility of the HINTEGRA prostheses in the context of total ankle replacement (TAR). We measured the length, width, height, and angles of the distal tibia and talus of 51 cadavers and compared these measurements with the corresponding dimensions of the HINTEGRA prostheses. The male ankles were larger than the female ones as was expected, but their overall shapes did not differ, which fact validates use of the prostheses irrespective of patients' sex. The dimensions of the talus itself did not differ significantly from those previously reported for American whites and blacks and South African whites. This might suggest a possibility that the HINTEGRA prostheses, being used in these countries, would be compatible to Korean ankles, too. In fact, the length range of the talar components was generally compatible with those derived from cadaveric measurements of the trochlea. However, the widths of the tibial and talar components were not completely compatible to Korean ankles. Above all, the length of the large-sized tibial components was much longer than the largest ankles, which would confine the choice of prosthesis mainly to small-sized ones for arthroplasty in Korea. Even though these prostheses are currently used, some modifications are needed to extend their usability in Korea, such as shortening and width/length ratio adjustment of the tibial component, and of the talar component accordingly

After catastrophic failure of first generation, joint replacement as treatment option for ankle osteoarthritis is undergoing a revival with improved second generation designs. Short to mid-term results reportedly equal those of ankle arthrodesis in terms of complications and revision, but preserving joint motion and protecting neighbouring midfoot joints from overuse and consecutive osteoarthritis. However, most reports derive from developers centres excluding the learning curve. We present clinical results and subjective outcome of an initial patient series undergoing ankle replacement in an independent centre. From January 2004 to January 2008 a Hintegra. ®. prosthesis was implanted in 39 consecutive patients (41 ankles), average age 60.7 years (range 36.6–85.0), 13 males and 25 females. Repeated clinical follow up was done for an average of 2.2 years (range 0.5–4.3). All patients whose operation had been more than 0.7 years before were sent the FAOS (Foot and Ankle Outcome Score) in order to record the subjective outcome. Pre-operative diagnoses were posttraumatic osteoarthritis in 26 cases (63.4%), primary osteoarthritis in 9 cases (22%) and rheumatoid arthritis in 6 cases (14.6%). Clinical examination did not show significant improvement of mean range of motion, dorsiflexion and plantarflexion compared with the preoperative status. The change in motion highly correlated with the preoperative mobility (r=0,8; p< 0.001): patients with the largest preoperative range of motion were the ones to lose most mobility, whereas patients with low preoperative motion gained mobility. About 60% of the patients achieved 25° to 30° total range of motion regardless of their preoperative mobility. Early postoperative complications occurred in 14 patients (34.1%). In all five subclasses of the FAOS a significant improvement was achieved within the observation period. Reduction of pain had the greatest impact on the improvement of quality of life, whereas change in mobility did not have any influence. Joint replacement is a valuable treatment option for ankle osteoarthritis. There are however a series of early complications and restrictions of subjective outcome a surgeon has to be aware of when selecting an individual patient for ankle replacement. Further studies are needed to detect in which cases arthrodesis or prosthesis is preferable

Background: The purpose of the present study was to report the perioperative complications that occurred among the initial 50 consecutive cases of HINTEGRA total ankle replacement. Methods: This was a retrospective study of 50 cases composed of 30 men and 18 women of average age 57 years. Perioperative complications were used to compare the first 25 cases (Group A) with the subsequent 25 (Group B). Results: Perioperative complications occurred in 15 cases (60%) in Group A but in only five (20%) in Group B. No major wound complications requiring a soft-tissue coverage procedure were encountered. Minor wound complications occurred in three cases in each group, and resolved with skin grafting or topical dressing changes. One deep infection occurred in Group A, which required implant removal and antibiotic impregnated spacer prior to revision TAR. Four patients sustained intraoperative malleolus fractures in Group A, but only one in Group B. Coronal malposition of the tibial component occurred in three cases in Group A and in two in Group B. Sagittally increased slope of the tibial component occurred in two cases in only Group B and sagittal malposition of the talar component occurred in two cases in only Group A. There were 7 instances of anterior translation of the talar component with respect to the tibial component; four in Group A and three in Group B. Conclusions: The results of the present study suggest that TAR has a steep learning curve. Moreover, knowledge of the perioperative complications of TAR may reduce the incidence of potential complications

Background. Total ankle arthroplasty (TAA) with the use of third generation implants has demonstrated favorable clinical results and improved survival. However, few studies have compared the different types of implants. The purpose of this study was to perform a retrospective evaluation of patient outcomes and complications by comparing TAA procedures performed with HINTEGRA versus MOBILITY systems. Methods. Fifty-two consecutively enrolled patients (28 men and 24 women; mean age 64.8 years) underwent TAA using HINTEGRA (21 ankles) or MOBILITY (33 ankles) between September 2004 and July 2012. Visual analog scale (VAS) pain scores and the American Orthopedic Foot and Ankle Society (AOFAS) ankle-hindfoot scores were determined at each follow-up visit. The radiographs were reviewed to assess component positioning, radiolucency, heterotopic ossification and other factors. Results. The mean follow-up period was 28.3 months in the HINTEGRA group and 32.5 months in the MOBILITY group. VAS decreased from 8.3 to 2.0 for the HINTEGRA group and from 7.9 to 2.7 for the MOBILITY group. The AOFAS score increased from 43.8 to 87.3 for the HINTEGRA group and from 46.6 to 83.7 for the MOBILITY group. Intra- and postoperative malleolar fractures were not noted in the HINTEGRA group, whereas 5 ankles (15.2%) in the MOBILITY group sustained this injury (P=.144). Ankle impingement syndrome was noted in 8 ankles (38.1%) in the HINTEGRA group and 3 (9.1%) in the MOBILITY group (P=.015). However, no significant differences in postoperative osteolysis and neuralgia were noted between the groups. Conclusions. HINTEGRA and MOBILITY implants both exhibited favorable clinical outcome without significant differences. However, in terms of complications, ankle impingement syndrome was significantly more common in the HINTEGRA group, while intraoperative malleolar fracture was observed in only the MOBILITY group

History and Background: The HINTEGRA. ®. Total Ankle Prosthesis was designed in 2000 by Dr. B. Hintermann (Basel, Switzerland); Dr. G. Dereymaeker (Pellenberg, Belgium); Dr. R. Viladot (Barcelona/Spain); and Dr. P. Diebold (Maxeville, France), and is manufactured by Newdeal SA in Lyon, France. Design Features: The HINTEGRA. ®. Total Ankle Prosthesis is a non-constrained, three-component system that provides inversion/eversion stability. Axial rotation and normal flexion/extension mobility are provided by a mobile bearing element. Limits of motion are dependent on natural soft-tissue constraints: no mechanical prosthetic motion constraints are imposed for any ankle movement with this device. The HINTEGRA. ®. ankle uses all available bone surface for support. The anatomically shaped, flat tibial and talar components essentially resurface the tibia and talar dome, respectively, and wings hemiprosthetically replace degenerate medial and lateral facets (a potential source of pain and impingement). No more than 2 to 3 mm of bone removal on each side of the joint is necessary to insert the tibial and talar components. On the tibial side, most importantly, the bony architecture remains intact, and in particular, the anterior cortex is preserved. Perfect apposition with the hard subchondral bone is achieved by the flat resection of the bone and the flat surface of the component. Primary stability for coronal plane motion is provided by two screws inserted into the anterior shield, in the upper part of oval holes so that the settling process of the component is not hindered by axial loading. On the talar side, additional anterior support is provided by a shield, and pressfit is provided by the slightly curved wings. Two pegs facilitate the insertion of the talar component and provide additional stability, particularly against anterior-posterior translation. Another advantage of this concept is the instrumentation that allows reliable implantation of components. Technique: The prosthesis is implanted through an anterior approach. In the case of malalignment, ligamentous instability, and concomitant osteoarthrosis of the distal joints, additional surgeries are considered before prosthetic implantation. Complications: In the beginning, a major concern was the positioning of the talar component, which tended to slide too posteriorly while impacting and press fitting. With the addition of two talar pegs, the current design may resist such translational forces during press fitting. There is evidence that positioning of the talar component too posteriorly may cause pain and limit dorsiflexion of the foot (probably because the posterior aspects of the deltoid ligament are over-tensioned), thereby the intrinsic forces are also increased which may cause unacceptable high shear forces at the bone-implant interface and/or component instability. In all but one of the seven revised talar components (out of the author’s first 400 cases), the component was positioned too posteriorly. There is a potential risk for dislocation of the meniscal component either laterally or medially as long as no appropriate alignment and/or ligament balancing have been achieved during surgery. The author encountered this problem only in two of the first twenty cases; thereafter, no such complications occurred probably because of better understanding alignment and balancing the ankle. A potential concern in uncemented resurfacing prostheses is the use of screws that may create stress shielding. The HINTEGRA. ®. ankle, however, uses oval holes on the tibial side so that some settling of the component during osteointegration is possible. As screw fixation is located eccentric to the load transfer area, the potential for stress shielding is in addition minimized. Salvage of Complications: Special revision implants are available for salvage of failed components. On tibial side, components with a thicker plateau may serve to replace loosed bone stock and to get firm bony support more proximally, thereby preserving the original joint line (that means, the ankle ligaments are supposed to be properly used for stabilizing and guidance of the joint). On talar side, components with a flat undersurface allow flat resection of the talus, thus providing a wide area of bone support to the revision component. Results: Between 05/2000 and 12/2006, 340 primary TAA were performed in 322 patients (females, 165; males, 157, age 57.3 ± 13.4 years). Underlying diagnosis was posttraumatic osteoarthritis in 272 ankles, primary osteoarthritis in 26 ankles and inflammatory arthritis in 42 ankles. All patients were clinically and radiologically assessed after 6.2 (1.1–7.5) years, and survivorship analysis was calculated. Revision of a metallic implant or conversion into ankle arthrodesis was taken as the endpoint. The AOFAS Hindfoot Score improved from 42.1 (14–61) points preoperatively to 78.6 (44–100) points at follow-up. 205 ankles (60.5%) were completely pain free. The average range of motion was clinically 32.2° (range, 15° to 55°), and under fluoroscopy (that is, true ankle motion) 30.4° (range, 7° to 62°). Four ankles were revised to TAA (component loosening, 3; pain, 1), and 2 ankles (component loosening and recurrent misalignment, 1; pain, 1) were revised to ankle arthrodesis. Overall survivorship at 6 years was 98.2%, being 97.9% for the talar component and 98.8% for the tibial component. Four ankles (1.2%) were successfully revised, and the obtained result at latest follow-up did not differ from those ankles without complications. Whereas, 2 ankles (0.6%) were revised to ankle arthrodesis. In another series of 37 patients (37 ankles: STAR, 26 ankles; HINTEGRA, 3 ankles; AGILITY, 3 ankles, Büchel-Pappas, 2 ankles; MOBILITY, 2 ankles; SALTO, 1 ankle) with failed total ankle arthroplasty, revision arthroplasty was performed with the HINTEGRA. ®. ankle. All but one surgery were successful. At a mean follow-up of 3.6 (1.2–6.4) years, 29 patients (78.4%) were satisfied with the obtained result. The AOFAS Hindfoot Score improved from 39.2 (23–58) points pre-operatively to 72.8 (54–95) points. All but on implants were radiographically stable; in one case, the tibial component showed, at one year, still a radioluscency which may be considered as loosening. As the patient is completely pain free, no revision surgery was done. In another series of 29 patients (30 ankles), a painful ankle fusion was taken down and ankle arthroplasty was performed with the HINTEGRA. ®. ankle. All surgeries were successful. At a mean follow-up of 3.4 (2–7.6) years, 24 patients (80%) were satisfied with the obtained result. The AOFAS Hindfoot Score improved from 34.1 (18–47) points preoperatively to 69.4 (48–90) points. The obtained motion for dorsi-/plantar flexion was clinically 23.5° (10°–40°) [52.6% of contra lateral ankle), and radiographically (“true ankle motion”) 24.5°(8°–24°) [54.4% of contra lateral ankle]. The author’s overall experience: more than 750 replacements with the HINTEGRA. ®. ankle in the last 8 years. The learning curve was rather long as some adjustments had to be performed, and there was need of some time to understand “ligament balancing” in ankle replacement in more detail. However, since then, an extremely high satisfaction rate was obtained, and most patients are doing very well. The revision rate has also turned down to < 2% despite, with increased experience, more complex cases may have been considered for ankle replacement. Conclusion: Obviously, TAA using a current anatomic design of 3-component prosthesis (HINTEGRA) have evolved to a safe procedure with reliable results at mid- to long-term. These encouraging results support our belief that TAA has become a viable alternative to ankle arthrodesis even for younger patients and more difficult conditions, as often the case in posttraumatic osteoarthritis

The purpose of this study was to review the total ankle arthroplasties performed in consecutive series of 78 ankles and to determine the short-term results in cases with over 12 months follow-up. Preoperative diagnoses were post-traumatic osteoarthritis in 40 ankles (51.3%), primary osteoarthritis in 32 ankles (41.0%), and systemic arthritis in six ankles (7.7%). HINTEGRA. ®. (Newdeal SA, Lyon, France) total ankle system was used in all cases. Fifty-five total ankle arthroplasties including four revision cases, followed up for over 12 months (range, 13~49 months) were included in this study. Ankles were divided into three groups according to the coronal plane deformity in preoperative standing ankle AP radiograph; Varus (≥10°; 20 ankles (39.2%)), neutral (< 10° varus or valgus; 25 ankles (49%)), and valgus (≥10° valgus; 6 ankles (11.8%)). Various additional surgeries were performed simultaneously with the arthroplasty to correct the deformities; deltoid ligament release (25 cases), posterior tibialis tendon lengthening (2 cases), peroneus longus tendon transfer to brevis (5 cases), lateral ankle reconstruction with modified Broström procedure (4 cases), lateral closed-wedge calcaneal osteotomy (3 cases), percutaneous heel cord lengthening (19 cases), and gastrocnemius recession (1 case). In one patient with severe valgus deformity, staged total ankle arthroplasty was conducted after primary triple arthrodesis. Preoperative and postoperative visual analogue scale (VAS), American Orthopaedic Foot and Ankle Society (AOFAS) score, range of motion (ROM), as well as patient’s satisfaction and willingness to receive the operation again were evaluated The results were compared among the three groups. Serial radiographs were reviewed for any radiological changes. AOFAS score has improved from 54.3 ± 11.4 pre-operatively to 79.2 ± 11.4 at last follow-up. VAS has decreased from 6.8 ± 1.6 to 3.2 ± 1.6. Mean improvement in ROM was 15.6 ± 16.2 degrees. Forty-eight cases (873%) were satisfied with excellent or good results and 49 cases (89.1 %) were willing to receive the operation again. No significant differences in the postoperative VAS (p=0.14), AOFAS score (p=0.79), and ROM (p=0.06) were found among the three groups. Hetero-topic ossifications were observed in 12 cases (23.5%) and periosteal reactions proximal to medial malleolus occurred in four cases (7.8%). Perioperative complications include one intraoperative medial malleolus fracture which was successfully managed with two cannulated-screws, and one medial malleolar stress fracture at six weeks after surgery which has healed spontaneously. One case with osteolysis around tibial screws was managed with bone graft. One case with deep fungal infection was converted to arthrodesis after infection control. Four ankles had to be revised including three cases of polyethylene bearing change due to dislocation, and one case of tibial component and bearing change due to loosening. The patient with revised tibial component was converted to arthrodesis due to recurred loosening. The Kaplan-Meier cumulative survival rate was 90.9% at 12 months and 87.8% at 49 months postoperatively. The short term clinical results of HINTEGRA ankles showed favorable results. No significant differences were observed among different groups of coronal plane deformities when adequate additional surgeries were performed simultaneously. Long term follow-up study is required

Aims

Revision rates for ankle arthroplasties are higher than hip or knee arthroplasties. When a total ankle arthroplasty (TAA) fails, it can either undergo revision to another ankle replacement, revision of the TAA to ankle arthrodesis (fusion), or amputation. Currently there is a paucity of literature on the outcomes of these revisions. The aim of this meta-analysis is to assess the outcomes of revision TAA with respect to surgery type, functional outcomes, and reoperations.

As an alternative to ankle replacement, ankle arthrodesis remains a mainstay in the treatment of end-stage arthritis. Arthroscopic techniques for ankle arthrodesis have more recently been developed, although there has been limited research exploring the cost of arthroscopic (AAA) versus open ankle arthrodesis (OAA), and comparing ankle fusions to replacement (TAA). We hypothesise that resource use after AAA will be lower than that after OAA, and both will be lower than TAA. We performed a retrospective review of a prospectively collected database. The COFAS database was used to identify patients with >2 years of follow up who have undergone AAA, OAA or Hintegra TAA at St Paul's Hospital between 2003–2010. Ninety patients with TAA, 52 with AAA and 56 with OAA met our inclusion criteria. The following data were documented: patient demographics (age, gender, presence of diabetes, inflammatory arthritis or any smoking history), factors related to the index surgery (type of surgery, OR time, length of stay) and factors relating to the post-operative course (number of post-operative clinic visits, OR time for re-operations, length of stay for additional hospital admissions). In terms of the index surgery, AAA required less initial OR time compared to either OAA or TAA. Initial length of hospital stay was significantly longer for both TAA and OAA, compared to AAA. Patients attended more follow-up visits after TAA or OAA compared to after AAA. In terms of additional OR time required, no significant differences were found among the groups. The most common reason for re-operation was infection or wound breakdown (38% of re-operations), followed by removal of hardware (15%). TAA also required significantly more additional days in hospital compared to either OAA or AAA. For all significant comparisons, p < 0.05. For each primary TAA, on average an additional one hour of surgery, three days in hospital and seven clinic visits were required on top of the cost factored for the primary arthroplasty. For each primary AAA, an additional four clinic visits, 23 minutes of revision surgery and one day in hospital were required. For each primary OAA, an average additional five clinic visits, three minutes of OR time, and 0.2 days of additional hospital stay occurred during follow up. Using several measures of resource use, we find that arthroscopic ankle fusions compare favourably to both ankle replacements and open ankle fusions. We also show that resource utilisation measurements can be a useful surrogate for complications, and that resource utilisation can demonstrate the practical implications of complications for patients, surgeons and health care resources

End-stage ankle arthritis (ESAA) is a debilitating disease that does not affect all individuals equally. Gender differences have been identified in patients with end-stage hip and knee arthritis and have stimulated research to explain these findings. The present study was undertaken to examine if gender has a significant effect on pre-operative disability and post-operative outcomes in patients with ESAA. Patients undergoing ankle arthrodesis (AA) or total ankle replacement (TAR) with minimum 2-year follow-up were identified in the Canadian Orthopaedic Foot and Ankle Society prospective ankle reconstruction database. Demographic data, revision data, patient satisfaction questionnaires, and outcome data using the Ankle Osteoarthritis Scale (AOS) and Short-form 36 (SF-36) health survey were collected. TAR: 384 patients were included, with 198 females and 186 males. Patient BMI, comorbidities, and duration of follow-up were similar between groups. Males were slightly older at the time of surgery (65.1 vs 62.4 years, p=0.01)). The most common etiology was post-traumatic arthritis for both genders, however females had a higher rate of rheumatoid arthritis (17% vs 5%, p=0.001). Implant types included STAR, Hintegra, and Mobility, and were similar between groups. Preoperatively females had higher rates of pain and disability, demonstrated by lower SF-36 physical component scores (PCS) (31.0 vs 34.5, p<0.001), and higher AOS pain (54.7 vs 51.1, p=0.05) and AOS disability scores (66.5 vs 59.6, p<0.001). Postoperatively, both groups had significant improvement in PCS, AOS pain, and AOS disability scores. Females, however, continued to demonstrate lower PCS scores (38.3 vs 41.9, p<0.001) and higher AOS disability (31.0 vs 25.8, p=0.02) than males. Regression analysis found that preoperative PCS, gender, age, and arthritis etiology all had a significant impact on postoperative PCS scores, with preoperative PCS scores having the largest impact. Preoperative AOS pain and disability scores had the largest impact on postoperative AOS pain and disability scores, respectively. Gender had no significant impact on AOS pain and disability scores postoperatively. Patient satisfaction was similar between males and females postoperatively. Secondary surgery was performed in 13.6% of females and 16.1% of males. Five males and five females underwent revision to arthrodesis. In patients with ESAA, females tend to have higher pre-operative levels of pain and disability compared to males, which persists post-operatively. This is consistent with the hip and knee arthroplasty literature. This finding may be due to females undergoing surgery at more advanced disease states, arthritis etiology, referral bias, or treatment bias. Both males and females have significant and similar degrees of improvement in pain and disability scores after TAR, and reoperation rates and patient satisfaction rates are similar despite the apparent disparity in outcomes

Recently with the introduction of operations using various instrument of total ankle arthroplasty, we are showing quite satisfactory short term results on the treatment of resolved pain of ankle joint. However, there have been reports of high probability of complication from total ankle arthroplasty to other arthroplasty applied to other joints. Therefore in order to make the results of ankle arthroplasty superior, it is necessary to reduce these complications. We try to analyze complications that occur often and come up with the best results. There were 45 cases of 42 patients of HINTEGRA. ®. (Newdeal SA, Lyon, France) model from November 2004 to August 2006. Follow up averaged 33.5 months, the average age of patients was 61.1 years, with 14 males and 28 females. We evaluated the complications and analyzed the causes of failures. There was a total 15 cases of complications; 5 cases of medical impingement syndrome, 3 cases of varus malposition, 2 cases of delayed healing of wound, 1 case of peroneal nerve problem, medial malleolar fracture, postoperative deep infection and gouty arthritis pain and Achilles tendinitis. Our conclusion is that total ankle arthroplasty had more complication rate than other joint arthroplasty, so we need a more meticulous preoperative and perioperative care

Purpose: To review short-term results in 25 patients that underwent total ankle replacement with implantation of a second generation prosthesis. Materials and methods: We reviewed 25 patients with ankle arthritis treated by total ankle replacement (TAR). Mean age of the patients was 58.2 years and mean follow-up 29.5 months. The cause of arthritis was posttraumatic in 17 cases. In all cases a HINTEGRA prosthesis was implanted. In 6 cases Achilles tendon lengthening was also performed. Review was carried out by anamnesis, clinical examination and radiological control. The ankle and hindfoot AOFAS scale was used to quantify clinical and functional results. Results: Mean AOFAS score improved from 24.0 to 80.1 points. No significant differences were found between cases of traumatic and non-traumatic origin. Pain was the parameter with the best evolution. Mean ankle mobility went from 19° to 26°. Five cases required revision surgery: 2 ankle arthrodeses due to prosthetic loosening, 2 Achilles tendon lengthenings and one release of tibio-talar impingement. Prosthetic survival rate at 29.5 months’ follow-up was 92%. All patients, except for the 2 cases that required arthrodesis, were satisfied or very satisfied. Conclusions: Total ankle replacement is an effective method for the treatment of ankle arthritis. Short term results are similar or better than those seen with arthrodesis

Data is scant on the critical question of whether patients with endstage ankle arthritis are better served by a fusion or a replacement. The STAR trial, a prospective case control study, comparing safety and efficacy of STAR ankle replacement at 24 months for 158 replacements and 66 fusions:. This FDA trial showed the STAR ankle replacement had better function, equivalent pain relief and a higher rate of complications and secondary procedures as ankles treated with fusion. A separate prospective cohort comparison of 200 ankle replacements vs. 94 ankle fusions performed by the collaborative consortium of Canadian Orthopaedic Foot and Ankle Surgeons (COFAS) suggests similar patient oriented outcomes at 24 months. Patients' self-assessment questionnaires do not show significant differences between the two groups. The main medium/long-term concerns with ankle replacement remain component subsidence (especially talar subsidence) and polyethylene wear. Forces across the ankle are considerable, and the orientation of those forces to the underlying trabecular structure are a concern. Whether 2 or 3 part ankles will provide better bearing wear results remains unknown. With older designs, at 10 years the Swedish registry found approximately 60% survivorship. This registry has also shown better survivorship in patients with rheumatoid disease and with increased surgeon experience. More recent results related to the Hintegra and AES components show better midterm (5 year) revision rates in selected surgeons hands, than seen with older designs. A large meta-analysis of ankle fusion and replacement published data by Haddad et al reported a mean nonunion rate of 10%. The main long-term concerns with ankle fusion are limitations of motion, and the development of premature arthritis in adjacent foot joints. In a study of an average of 9 year outcome of the Agility ankle replacement suggested that the incidence secondary arthritis is halved by replacement as compared to fusion

Background: The number of total ankle replacements has been raising in the last years. Most publications present short- and medium-term results. Comparison of outcomes is difficult because of inconsistent terminology and different parameters used. Moreover, poorly performing implants cannot be identified quickly because of low numbers, delayed reporting or publication bias. Methods: Therefore, we have developed a module for total ankle prostheses in the framework of the International Documentation and Evaluation System (IDES) for standardized and centralized documentation of TAA outcomes. Content validation was conducted with a single surgeon series of 74 HINTEGRA_ ankle replacements. Results: Between March 2004 and February 2008 74 patients were treated. The preoperative diagnosis was 18.9% osteoarthritis, 32.4% rheumatoid arthritis, 43.3% posttraumatic, 1.4% osteonecrosis and 4% others. There were intraoperative complications in 4%, local postoperative complications in 17.6% and revision surgeries in 16.2% of patients. The AOFAS hind-foot score improved from 23.8 points preoperative to 75.3 points after a mean followup time of 8.4 months. No significant differences in outcome were revealed between the various diagnostic groups. Conclusion: The IDES-forms facilitate a structured and standardized data collection that is feasible in a research orientated but also purely clinical setting; this because of the different extents to which data can be recorded. The consistent use of the system assures a stringent internal quality assurance, and more interesting, an external quality assurance by means of comparisons and benchmarking with other users feeding the data pool with the exact same variables and outcomes. The Hintegra ankle appeared as a safe device with low complication rates in the hands of a foot and ankle specialist. A surgical learning curve was seen in the first two years

Background:. There is little knowledge about wear performance of total ankle arthroplasties (TAR). However, revisions rates are high for TAR [1] and wear associated revisions are frequent [2]. Therefore, the aim of this study is . (1). To test the wear behavior of a TAR using a biomechanically valid testing scenario. (2). To test the influence of an alternative ceramic tibial component. (3). To test the long term wear performance of TAR. Material and Methods:. In the first part of this study the HINTEGRA (Smith & Nephew) TAR has been used for wear testing. Wear testing was performed on a modified AMTI knee simulator. Level walking according to a previous described testing standard [see abstract: Development of a force controlled testing scenario for total ankle replacements] has been used. Level walking was simulated in three clinical relevant situations, first simulating the reduced loading after implantation, secondly simulating an increasing range of motion and at last a loading pattern orientating at the loadings in the native/healthy joint. Every simulation was run for 3 million cycles, resulting in 9 million total cycles. In the second part of this study the metal tibial plateau was replaced by a ceramic tibial component (Biolox® Delta, CeramTec). Simulation was run, as described above, for additional 9 million cycles. Termed as a long term test, in total 18 million cycles of testing are performed. Results:. When simulating level walking with loadings assumed after implantation a wear rate of 19.5 ± 1,49 mg/Mc has been determined. Increasing the range of motion lead to a wear rate of 18.0 ± 2,56 mg/Mc and simulating loading as assumed in a healthy joint, a wear rate of 23.8 ± 1,47 mg/Mc was determined. When replacing the metal tibial component by a ceramic tray the wear rate decreased between 20–30% dependent on the tested scenario. No delamination occurred during 18 millon cycles of testing. Conclusion:. In this study, high wear rates for TAR were determined. Compared to standardized wear testing of total knee replacements in our laboratory the wear rate of TAR was approximately 2.5 times increased. Ceramics seem to be an option to decrease the wear rate. The high wear rate of the polyethylene may be a factor contributing to the high revision rates seen in TARs

Ankle replacements appear to offer a good alternative to fusion in most arthritic conditions. Use of mobile bearings have significantly improved results of ankle replacement. These have a significant minor complication rate including nerve injury, fractures. One of the significant complications noted in our series was medial impingement. 34 Buechel-Pappas total ankle replacements performed by the senior author from October 1999 to May 2004 were reviewed retrospectively. Mean follow up of 2.8 years. 8 patients reported medial impingment symptoms at follow up. 3 patients underwent repeat surgery for this problem. One patient underwent arthroscopic debridement of scar tissue and impinging bone by another surgeon which gave good symptomatic relief. Two other patients had tibialis posterior tendonitis and underwent surgical decompression of the tendon. Both were found to be having degenerative tendons with partial tears. We discuss the findings, literature review and other complications of ankle replacements as well. Whether medial impingement is due to implant design or inherent pathology of ankle has to be studied further. Other implant designs like Agility may treat arthritis in medial and lateral gutters but can still cause soft tissue impingement. Whether these are due to implant design, residual arthritis in medial recess or soft tissue pathology is uncertain. This may be caused by the cylindrical shape of talar component (the physiologic talus has a cone shape with smaller radius on medial side). This has not been proven yet, but has been addressed in newer designs like Salto and Hintegra prostheses

Purpose. To investigate the effect of obesity on functional outcome following total ankle arthroplasty. Method. We identified 43 obese patients (46 ankles) (BMI > 30kg/m2), using a prospectively collected database of total ankle arthroplasties. Inclusion criteria included: (a) Post-traumatic or inflammatory arthritis; (b) Minimum two-year follow-up, (c) Coronal plane deformity less than 10 degrees. Exclusion criteria: (a) Co-morbidity affecting physical function; (b) Recent total joint arthroplasty. American Orthopaedic Foot and Ankle Society (AOFAS), Ankle Osteoarthritis Scale (AOS) and SF-36 questionnaires were used preoperatively and at latest follow-up. Revision was defined as any intervention requiring replacement of part or whole of the prosthesis. A control group of non-obese individuals (BMI 18.5–29.9kg/m2) was devised matching for age within 10 years, gender, diagnosis, implant and length of follow-up (within 1 year). From the original group of 46 ankles, we matched 28 ankles, thereby constructing two groups for comparison (matched obesity and control). Results. From the original obesity group (n=46, mean BMI 34.7, age 65.1 years and follow-up 3.5 years), four patients were lost to follow-up. There were 10 revisions (21.7%) including five for liner exchange, four full component and one revision to fusion. Statistically significant (p<0.001) improvements were detected with all outcome measures (AOFAS, AOS and SF-36). In the matched obesity and control groups we used 11 STAR, 11 Mobility and six Hintegra implants. Delayed wound healing affected one patient in each group. In the matched obesity group (mean BMI 35), there were six revisions (three liner exchange, three full component) (21.4%), at a mean of 3.2 years. One patient was lost to follow-up (known to be revised). Statistically significant improvements were noted with all outcome measures. In the control group (mean BMI 26.1), there were three revisions (two liner exchange and one full component) (10.7%), at a mean of 2.3 years. All patients were followed-up. Statistically significant improvements were associated with all outcome measures except the mental component summary of the SF-36 (52.2 to 54, p=0.37). The same score pre-operatively was lower in the matched obesity group (45 vs. 52.2, p=0.193). Overall, no difference was found in mean outcome score improvement between groups. In the matched obesity group, the mean pre-operative AOS pain score was higher (58.8 vs. 46.5) (p=0.016), as was the preoperative AOS disability score (68.4 vs. 58.5) (p=0.082). The mean post-operative AOS pain and disability scores were also higher, although not reaching significance (p=0.096 and p=0.241 respectively). Conclusion. Obesity is associated with greater functional and psychological preoperative burden, although the overall improvement in functional outcome is comparable to non-obese matched controls. Obese patients can expect a significantly higher revision rate (21.4% vs 10.7%) within five years of surgery

Ankle replacements have improved significantly since the first reported attempt at resurfacing of the talar dome in 1962. We are now at a stage where ankle replacement offers a viable option in the treatment of end-stage ankle arthritis. As the procedure becomes more successful, it is important to reflect and review the current surgical outcomes. This allows us to guide our patients in the treatment of end-stage ankle arthritis. What is the better surgical treatment – arthrodesis or replacement?