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Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_1 | Pages 22 - 22
1 Feb 2021
Kamath A Acuna A Jella T Cwalina T Samuel L
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Introduction. Innovations in orthopaedic technology and infrastructure growth often require significant funding. Although an increasing trend has been observed for third-party investments into medical startups and physician practices, no study has examined the role of this funding in orthopaedics, including the influence of venture capital (VC). Therefore, this study analyzed trends in VC investments related to the field of orthopaedic surgery, as well as the characteristics of companies receiving said investments. Methods. Venture capital investments into orthopaedic-related businesses were reviewed from 2000–2019 using Capital IQ, a proprietary market intelligence platform documenting financial transactions. The dataset was initially filtered to include healthcare-related venture capital transactions pertaining to the field of orthopaedic surgery. The final list of VC investments and their corresponding businesses were categorized by transaction year, amount (in USD), and orthopaedic subspecialty. The number and sum of VC investments was calculated both annually and cumulatively across the entire study period. Linear regression was used for trend analysis within two distinct, decade-long timeframes (2000–2009 and 2010–2019) and one-way analysis of variance was used to assess differences across orthopaedic subspecialties. Results. Over the course of two decades, 672 VC investments were made into orthopaedic-related businesses, representing a total of $3.5 billion. Both the number and dollar value of transactions were greater in the second decade (2010–19) (233, $1.9 billion), compared to the first decade (439, $1.6 billion). Linear regression revealed significant trends in both the quantity and dollar amount of VC transactions within the decade from 2000–09 (p = 0.0002 and p = 0.0143, respectively) but no such trend in the latter decade (Figure 1A-B, Figure 2A-B). Throughout both decades studied, the largest and most frequent VC investments took place within Spine and Adult Reconstruction (Figure 3). One-way analysis of variance revealed significant differences in the annual frequency and amount of investment across orthopaedic subspecialties (p < 0.001 and p < 0.001, respectively). Discussion and Conclusion. The present data suggest that an initially rising trend in VC investment in orthopaedic-related businesses may have plateaued over the past decade. These findings may have important implications for continued investment into orthopaedic innovations and collaboration between the surgical community and private sector, as well as the perceived profitability of orthopaedic industries by third-party interests. For any figures or tables, please contact the authors directly


The Bone & Joint Journal
Vol. 104-B, Issue 4 | Pages 519 - 528
1 Apr 2022
Perry DC Arch B Appelbe D Francis P Craven J Monsell FP Williamson P Knight M

Aims. The aim of this study was to inform the epidemiology and treatment of slipped capital femoral epiphysis (SCFE). Methods. This was an anonymized comprehensive cohort study, with a nested consented cohort, following the the Idea, Development, Exploration, Assessment, Long-term study (IDEAL) framework. A total of 143 of 144 hospitals treating SCFE in Great Britain participated over an 18-month period. Patients were cross-checked against national administrative data and potential missing patients were identified. Clinician-reported outcomes were collected until two years. Patient-reported outcome measures (PROMs) were collected for a subset of participants. Results. A total of 486 children (513 hips) were newly affected, with a median of two patients (interquartile range 0 to 4) per hospital. The annual incidence was 3.34 (95% confidence interval (CI) 3.01 to 3.67) per 100,000 six- to 18-year-olds. Time to diagnosis in stable disease was increased in severe deformity. There was considerable variation in surgical strategy among those unable to walk at diagnosis (66 urgent surgery vs 43 surgery after interval delay), those with severe radiological deformity (34 fixation with deformity correction vs 36 without correction) and those with unaffected opposite hips (120 prophylactic fixation vs 286 no fixation). Independent risk factors for avascular necrosis (AVN) were the inability of the child to walk at presentation to hospital (adjusted odds ratio (aOR) 4.4 (95% CI 1.7 to 11.4)) and surgical technique of open reduction and internal fixation (aOR 7.5 (95% CI 2.4 to 23.2)). Overall, 33 unaffected untreated opposite hips (11.5%) were treated for SCFE by two-year follow-up. Age was the only independent risk factor for contralateral SCFE, with age under 12.5 years the optimal cut-off to define ‘at risk’. Of hips treated with prophylactic fixation, none had SCFE, though complications included femoral fracture, AVN, and revision surgery. PROMs demonstrated the marked impact on quality of life on the child because of SCFE. Conclusion. The experience of individual hospitals is limited and mechanisms to consolidate learning may enhance care. Diagnostic delays were common and radiological severity worsened with increasing time to diagnosis. There was unexplained variation in treatment, some of which exposes children to significant risks that should be evaluated through randomized controlled trials. Cite this article: Bone Joint J 2022;104-B(4):519–528


Bone & Joint Open
Vol. 1, Issue 4 | Pages 80 - 87
24 Apr 2020
Passaplan C Gautier L Gautier E

Aims. Our retrospective analysis reports the outcome of patients operated for slipped capital femoral epiphysis using the modified Dunn procedure. Results, complications, and the need for revision surgery are compared with the recent literature. Methods. We retrospectively evaluated 17 patients (18 hips) who underwent the modified Dunn procedure for the treatment of slipped capital femoral epiphysis. Outcome measurement included standardized scores. Clinical assessment included ambulation, leg length discrepancy, and hip mobility. Radiographically, the quality of epiphyseal reduction was evaluated using the Southwick and Alpha-angles. Avascular necrosis, heterotopic ossifications, and osteoarthritis were documented at follow-up. Results. At a mean follow-up of more than nine years, the mean modified Harris Hip score was 88.7 points, the Hip Disability and Osteoarthritis Outcome Score (HOOS) 87.4 , the Merle d’Aubigné Score 16.5 points, and the UCLA Activity Score 8.4. One patient developed a partial avascular necrosis of the femoral head, and one patient already had an avascular necrosis at the time of delayed diagnosis. Two hips developed osteoarthritic signs at 14 and 16 years after the index operation. Six patients needed a total of nine revision surgeries. One operation was needed for postoperative hip subluxation, one for secondary displacement and implant failure, two for late femoroacetabular impingement, one for femoroacetabular impingement of the opposite hip, and four for implant removal. Conclusion. Our series shows good results and is comparable to previous published studies. The modified Dunn procedure allows the anatomic repositioning of the slipped epiphysis. Long-term results with subjective and objective hip function are superior, avascular necrosis and development of osteoarthritis inferior to other reported treatment modalities. Nevertheless, the procedure is technically demanding and revision surgery for secondary femoroacetabular impingement and implant removal are frequent. Cite this article: 2020;1-4:80–87


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_11 | Pages 9 - 9
1 Jun 2017
Balakumar B Patel K Madan S
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Purpose. We share our experience in management of failed in-situ pinning in severe unstable Slipped Capital Femoral Epiphysis (SCFE) by surgical dislocation approach. Method. A retrospective review of hip database from 2006 to 2013 showed 41 children underwent surgical dislocation for SCFE. We identified seven who had severe slip with failed in-situ pinning. Results. The mean age at presentation was 11.9 years (10–14 years). The average interval between in-situ pinning and surgical dislocation was 10 months (2 to 18 months). The mean follow-up was 50.14 months (25 – 66 months). The mean preoperative slip angle in the oblique plane was 76° (61.1° – 121.5°), the mean preoperative alpha angle was 127.3° (93.1° – 145°), and preoperative head neck offset was −12.7mm (0 – −21.2mm). The mean corrections at latest follow-up were oblique plane slip angle 20.6° (4.2° – 41.8°), alpha angle 51.3° (45.3° – 58°), and head-neck offset 9.5mm (1 – 16.2mm). The mean Modified Harris Hip Score (MHHS) preoperatively was 19.57 (0 – 56) and the mean non-arthritic hip score (NAHS) was 21.07 (5 – 51.5). The mean MHHS at the last visit was 88.97 (71 – 96) and NAHS was 84.28 (69.5 – 91). All patients had gross external rotation deformity at presentation; mean internal rotation of 25° ranging from (0 – 40°) was achieved at follow-up. Four patients had avascular necrosis identified on subtraction MRI scan preoperatively. These four underwent second stage hinged distraction of the hip. Mean duration of hinged distraction was 7.6 months. At follow-up 4 had Tonnis 0, one Tonnis 1 and two Tonnis 2 grade of osteoarthritis. Conclusion. The short-term result of our protocol for management of failed in-situ pinning by staged surgical dislocation and hinged distraction has been encouraging. This could potentially prolong the life of native hip to the third decade of life before definitive salvage procedures could be contemplated


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_3 | Pages 72 - 72
23 Feb 2023
Ellis S Heaton H Watson A Lynch J Smith P
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Prosthetic joint infections (PJI) are one of the most devastating complications of joint replacement surgery. They are associated with significant patient morbidity and carry a significant economic cost to treat. The management of PJI varies from antibiotic suppression, debridement, antibiotics, and implant retention (DAIR) procedures through to single/multiple stage revision procedures. Concerns have been raised recently in relation to the rising number of revision arthroplasty procedures that are being undertaken in relation to infection. This database aims to collect data on all PJIs that have been managed in the Australian Capital Territory (ACT) region. This will allow us to investigate the microbial trends, outcomes of surgical intervention and patient outcomes within our local population. This database will incorporate diagnostic, demographic, microbiological and treatment information in relation to local PJI cases. The data will be collated from the local infectious diseases database, hospital medical records, and where available the Australian Orthopaedic Association National Joint Replacement Registry Data. The first 100 cases of PJI were assessed. 76% were defined as being acute. 56% of the patients received antibiotics prior to their diagnosis however only 3% were culture negative. 89% were monomicrobial and 11% polymicrobial. The intended management strategy was a DAIR in 38% of patients and a 2-stage revision in 12% of cases. The intended management strategy was successful in 46% of the patients. The ACT is uniquely placed to analyze and create a local PJI database. This will allow us to guide further treatment and local guidelines in terms of management of these complex patients


Bone & Joint Research
Vol. 6, Issue 8 | Pages 472 - 480
1 Aug 2017
Oduwole KO de SA D Kay J Findakli F Duong A Simunovic N Yen Y Ayeni OR

Objectives. The purpose of this study was to evaluate the existing literature from 2005 to 2016 reporting on the efficacy of surgical management of patients with femoroacetabular impingement (FAI) secondary to slipped capital femoral epiphysis (SCFE). Methods. The electronic databases MEDLINE, EMBASE, and PubMed were searched and screened in duplicate. Data such as patient demographics, surgical technique, surgical outcomes and complications were retrieved from eligible studies. Results. Fifteen eligible level IV studies were included in this review comprising 261 patients (266 hips). Treatment groups included arthroscopic osteochondroplasty, surgical hip dislocation, and traditional open osteotomy. The mean alpha angle corrections were 32.14° (standard deviation (. sd). 7.02°), 41.45° (. sd. 10.5°) and 6.0° (. sd. 5.21°), for arthroscopy, surgical hip dislocation, and open osteotomy groups, respectively (p < 0.05). Each group demonstrated satisfactory clinical outcomes across their respective scoring systems. Major complication rates were 1.6%, 10.7%, and 6.7%, for arthroscopy, surgical dislocation and osteotomy treatments, respectively. Conclusion. In the context of SCFE-related FAI, surgical hip dislocation demonstrated improved correction of the alpha angle, albeit at higher complication and revision rates than both arthroscopic and open osteotomy treatments. Further investigation, including high-quality trials with standardised radiological and clinical outcome measures for young patients, is warranted to clarify treatment approaches and safety. Cite this article: K. O. Oduwole, D. de Sa, J. Kay, F. Findakli, A. Duong, N. Simunovic, Y. Yi-Meng, O. R. Ayeni. Surgical treatment of femoroacetabular impingement following slipped capital femoral epiphysis: A systematic review. Bone Joint Res 2017;6:472–480. DOI: 10.1302/2046-3758.68.BJR-2017-0018.R1


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_3 | Pages 26 - 26
23 Feb 2023
George JS Norquay M Birke O Gibbons P Little D
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The risk of AVN is high in Unstable Slipped Capital Femoral Epiphysis (SCFE) and the optimal surgical treatment remains controversial. Our AVN rates in severe, unstable SCFE remained unchanged following the introduction of the Modified Dunn Procedure (MDP) and as a result, our practice evolved towards performing an Anterior Open Reduction and Decompression (AOR) in an attempt to potentially reduce the “second hit” phenomenon that may contribute. The aim of this study was to determine the early surgical outcomes in Unstable SCFE following AOR compared to the MDP. All moderate to severe, Loder unstable SCFEs between 2008 and 2022 undergoing either an AOR or MDP were included. AVN was defined as a non-viable post-operative SPECT-CT scan. Eighteen patients who underwent AOR and 100 who underwent MPD were included. There was no significant difference in severity (mean PSA 64 vs 66 degrees, p = 0.641), or delay to surgery (p = 0.973) between each group. There was no significant difference in the AVN rate at 27.8% compared to 24% in the AOR and MDP groups respectively (p = 0.732). The mean operative time in the AOR group was 24 minutes less, however this was not statistically significant (p = 0.084). The post-reduction PSA was 26 degrees (range, 13–39) in the AOR group and 9 degrees (range, -7 to 29) in the MDP group (p<0.001). Intra-operative femoral head monitoring had a lower positive predictive value in the AOR group (71% compared to 90%). Preliminary results suggest the AVN rate is not significantly different following AOR. There is less of an associated learning curve with the AOR, but as anticipated, a less anatomical reduction was achieved in this group. We still feel that there is a role for the MDP in unstable slips with a larger remodelling component


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 270 - 270
1 May 2006
Azzopardi T Sharma S Sherlock D
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Stickler’s syndrome, also called Hereditary Progressive Arthro-Ophthalmopathy, is an autosomal dominant connective tissue disorder with strong expressivity, characterised by ocular, orofacial, skeletal, cardiac, and auditory features. We describe a case of valgus slipped capital femoral epiphysis in a 13 year-old boy with Stickler’s syndrome. He presented at routine rheumatology clinic follow-up with a 1-month history of progressively worsening right hip pain, which radiated to the knee. He underwent insitu cannulated screw fixation of the right slipped capital femoral epiphysis. Joint pains are a common manifestation in Stickler’s syndrome and this might delay the diagnosis of slipped capital femoral epiphysis. Valgus slipped capital femoral epiphysis is a rare entity. Obesity and the increased femoral anteversion are predisposing factors. Insitu fixation with a single cannulated screw is the treatment of choice


Aims. Slipped capital femoral epiphysis (SCFE) is one of the most common hip diseases of adolescence that can cause marked disability, yet there is little robust evidence to guide treatment. Fundamental aspects of the disease, such as frequency, are unknown and consequently the desire of clinicians to undertake robust intervention studies is somewhat prohibited by a lack of fundamental knowledge. Methods. The study is an anonymized nationwide comprehensive cohort study with nested consented within the mechanism of the British Orthopaedic Surgery Surveillance (BOSS) Study. All relevant hospitals treating SCFE in England, Scotland, and Wales will contribute anonymized case details. Potential missing cases will be cross-checked against two independent external sources of data (the national administrative data and independent trainee data). Patients will be invited to enrich the data collected by supplementing anonymized case data with patient-reported outcome measures. In line with recommendations of the IDEAL Collaboration, the study will primarily seek to determine incidence, describe case mix and variations in surgical interventions, and explore the relationships between baseline factors (patients and types of interventions) and two-year outcomes. Discussion. This is the first disease to be investigated using the BOSS Study infrastructure. It provides a robust method to determine the disease frequency, and a large unbiased sample of cases from which treatment strategies can be investigated. It may form the basis for definitive robust intervention studies or, where these are demonstrated not to be feasible, this may be the most robust cohort study


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_6 | Pages 45 - 45
1 Apr 2018
Gharanizadeh K
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Introduction. In situ pinning for classic slipped capital femoral epiphysis(SLIP) is evolving to a more direct and anatomic realignment of proximal femoral epiphysis; but in no study the result of such a treatment in Valgus Slip, an uncommon type of slipped capital femoral epiphysis, has been reported. Material and methods. Three hips in three patients (one male, two female) with valgus SCFE were treated by sub-capital realignment (two hips) or femoral neck osteotomy (one hip) for anatomic realignment of proximal femoral epiphysis. Extended retinacular flap technique performed through surgical hip dislocation in all hips. They followed clinically by Merle d'Aubigne Scale and visual analog scale for pain and radiographically for AVN, recurrence of SLIP, chondrolysis and osteoarthritis. Result. The age of the patients was 10,11 and 18 years. In all hips the neck-shaft angle was increased.18 years old male had bilateral chronic valgus SLIP with severe retro tilt of the head over the neck and bilateral acetabular dysplasia.11 years old girl with an acute valgus SLIP also had bilateral acetabular dysplasia and in 10 years old girl only one hip presented with acute on chronic valgus SLIP. All had severe displacement. The mean preoperative epiphyseal shaft angle (ESA) of 107.5° (range 85–125°) was reduced to 60° (range 55–70°) postoperatively. mean Merle d'Aubigne Scale was 16 and radiographically complete union and good alignment achieved without any complication. Conclusion. Anatomical realignment of proximal femoral epiphysis in this small series of patient with valgus type SCFE had good to excellent results


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_6 | Pages 140 - 140
1 Jul 2020
Railton P Powell J Parkar A Abouassaly M Kiefer G Johnston K
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Despite recent advances in the management of slipped capital femoral epiphysis (SCFE), controversy remains about the treatment of choice for unstable slips. Surgical dislocation and open reduction has the advantage of identifying and preserving the blood supply of femoral head thereby potentially reducing the risk of avascular necrosis, (AVN). There is large variation in the literature from several small series about reported AVN rates ranging from two to 66% for unstable SCFE treated with surgical dislocation. The aim of our study was to analyze our experience with acute open reduction and internal fixation of unstable acute and unstable acute on chronic slips using the technique of surgical dislocation described by Professor Reinhold Ganz. A retrospective review of 11 patients (12 hips) treated by surgical dislocation, reduction and pinning as the primary procedure for unstable acute and unstable acute on chronic SCFE in a tertiary referral children's hospital was undertaken. This represents the entire series treated in this manner from September 2007 to January 2018. These procedures were performed by a team of Orthopaedic surgeons with significant experience performing surgical dislocation of the hip including patients with chronic SCFE, Perthes' disease, impingement and acetabular fractures. Demographic data, intraoperative records, postoperative notes and radiographs including details of subsequent surgery were reviewed. There were seven boys and four girls with mean age of 13.4 years, range 11 to 15 years at the time of surgical dislocation. Out of 12 hips, two had acute unstable slip while the remaining 10 had acute on chronic unstable slip. Six patients had good or excellent results. The remaining six patients developed AVN of which three patients had total hip replacement at six months, 17 months and 18 months following primary procedure. Seven patients required more than one operation. Three patients lost their correction and required re fixation despite surgical dislocation, reduction and fixation being their primary procedure. This series demonstrates a high percentage of AVN (50%) in severe unstable SCFE treated with surgical dislocation despite careful attention to retinacular flap development and intra operative doppler studies. This is in direct contrast to our experience with subcapital reorientation with surgical dislocation in stable slips where excellent results were achieved with a low rate of AVN. Pre-operative imaging with MRI and perfusion studies may identify where ischemia has occurred and might influence operative treatment. Based on our results, we do not recommend routine use of surgical dislocation in unstable SCFE. This technique requires further scrutiny to define the operative indications in unstable SCFE


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_13 | Pages 111 - 111
1 Nov 2021
Mulder F Senden R Staal H de Bot R van Douveren F Tolk J Meijer K Witlox A
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Introduction and Objective. Slipped Capital Femoral Epiphysis (SCFE) is one of the most common hip disorders in children and is characterized by a proximal femoral deformity, resulting in early osteoarthritis. Several studies have suggested that SCFE patients after in situ fixation show an altered gait pattern. Early identification of gait alterations might lead to earlier intervention programs to prevent osteoarthritis. The aim of this study is to analyse gait alterations in SCFE patients after in situ fixation compared to typically developed children, using the Computer Assisted Rehabilitation Environment (CAREN) system. Materials and Methods. This is a cross-sectional, multi-center case-control study in the Netherlands. Eight SCFE patients and eight age- and sex-matched typically developed were included from two hospitals. Primary outcomes were kinematic parameters (absolute joint angles), studied with gait analysis using statistical parametric mapping (SPM). Secondary outcomes were spatiotemporal parameters, the Notzli alpha angle, muscle activation patterns (EMG), and clinical questionnaires (VAS, Borg CR10, SF-36, and HOOS), analyzed using non-parametric statistical methods. Results. Patients (mean BMI=28±9 kg/m. 2. ) showed altered gait patterns, with significantly increased external hip rotation and decreased downward pelvic obliquity during the pre-swing phase of the gait cycle compared to typically developed (mean BMI=22±3 kg/m. 2. ). Walking speed, cadence, % stance time, and step length were reduced in SCFE patients. Coefficient of variances of cadence, stance time, and step length were increased. Patients had a mean alpha angle of 64, SD=7.9. Clinical questionnaires showed that general health (SF-36) was 80±25, energy/fatigue (SF-36) was 67±15, pain (VAS) was 0±1.5, and total HOOS score was 85±18. Conclusions. SCFE patients after in situ fixation appear to have developed a compensation mechanism, showing slight alterations in gait parameters, good general health, little functional limitations of the hip, and no self-reported pain. Cam deformities, altered joint loading, and this compensation mechanism might influence long-term early osteoarthritis. BMI reduction should be implemented in care plans, as obesity might also play a role in unfavorable long-term outcomes


The modified Dunn procedure has the potential to restore the anatomy in hips with slipped capital femoral epiphyses (SCFE) while protecting the blood supply to the femoral head. However, there is controversy about the risks associated with the procedure especially in the most severe capital slips. Therefore, we report on (1) clinical outcome, (2) the cumulative survivorship with endpoints AVN and/or OA progression and (3) radiographic anatomy of the proximal femur at followup in patients treated with a modified Dunn procedure for severe SCFE. We performed a retrospective analysis involving 46 hips of 46 patients treated with a modified Dunn procedure for severe SCFE (slip angle >60°) between 1999 and 2016. Followup averaged 8 years, (range 1–17) with 2 patients lost to followup after one year. The mean age was 13 years (range 9–19 years). Mean preoperative slip angle was 64° (range 60–90) and 14 out of 46 hips (30%) presented with unstable slips. Clinical scores and PROMs were evaluated and the hips were followed standard x-rays. Cumulative survivorship (Kaplan-Meier) with three defined endpoints: (1) AVN; (2) progression by at least one OA grade according to Tönnis; (3) non-preserved hip joint. (1)Mean Harris Hip score (HHS) was 93 points (66–100) and mean Hip Disability and Osteoarthritis Outcome Score (HOOS) was 90 points (67–100) at last followup. (2)Cumulative survivorship was 93% at 10-year followup. Three hips reached an endpoint. Two hips (4%) had AVN, one of them underwent hip arthrodesis. One hip had OA progression. (3)Postoperative slip angle was 7° (1–16). Alpha angle on axial radiograph was 39° (26–71) at followup. 41/44 hips (93%) had no OA (Tönnis 0). The modified Dunn procedure largely corrected slip deformities with low apparent risk of progression to avascular necrosis or osteoarthritis at mean 8-years followup. The AVN rate in severe and unstable (30%) capital slip was 4% (2 hips) with this procedure


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_I | Pages 71 - 71
1 Mar 2005
Rooney BP Bennet GC
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Introduction: To determine whether there is a correlation between severity of the slip and duration of symptoms in patients presenting with slipped capital femoral epiphysis. Methods: 50 patients with slipped capital femoral epiphysis were identified from the Royal Hospital for Sick Children database from 1998 to 2003. Of these, 47 patients had casenotes and radiographs available. 12 patients had bilateral slips resulting in a total of 59 slipped capital femoral epiphyses studied. On the basis of their history, 16 of these hips were unstable and were excluded leaving 43 stable slips in 35 patients. Case-notes were reviewed and the exact age, weight, symptom duration and treatment were recorded. X-rays were assessed and the slip angle was measured by the technique described by Southwick. Results: The mean age of the patients was 11years 9months (7yrs 5 mths – 16 yrs 5mths). There were 19 males and 16 females. Weights were plotted against age on a centile chart with 85% of patients weighing > 75th centile for age.The mean duration of symptoms was 12.1weeks (2days – 52weeks)The mean slip angle was 22° (5° – 65°)There were 34 mild slips (< 30°), 8 moderate slips (30° – 60°) and 1 severe slip (> 65°). There was no statistical difference in duration of symptoms between these groups. Statistical analysis by ordinal regression analysis showed there was no correlation between slip severity and duration of symptoms. In addition, there was no correlation between slip severity and age or weight. Conclusion: There appears to be no relationship between slip severity and duration of symptoms in patients presenting with stable slipped capital femoral epiphysis


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 597 - 597
1 Oct 2010
Mavcic B Antolic V Iglic A Kralj-Iglic V Krizancic M Zupanc O
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Slipped capital femoral epiphysis is an important orthopaedic problem of early adolescence. Many hypotheses about its etiology have been proposed; still the underlying mechanisms are not clearly understood. The aim of our paper is to examine radiographic characteristics of hips at risk for slipped capital epiphysis. Two groups of hips were compared: a group of 100 asymptomatic hips contralateral to the slipped ones and a group of 70 age- and gender-matched healthy hips. The hips contralateral to the slipped ones were assumed to have identical morphology to the preslip-page morphology of the slipped hips. In each hip the following radiographic parameters were measured: the inter-hip distance, the femoral neck length/width, the pelvic height, the pelvic width, the femoral head radius, the coordinates of the abductor muscles trochanteric attachment, the inclination of the femoral epiphyseal growth plate, the femoral neck-shaft angle and the Wiberg center-edge angle. Subjects with hips at risk for slipping had significantly higher body weight (590 vs. 500 N; p < 0.001), larger diameter of the femoral neck (38.6 vs 37.3 mm; p = 0.027), higher (138.9 vs. 134.6 mm; p = 0.022) and wider pelvis (53.8 vs. 48.7 mm; p < 0.001) and more laterally placed abductor muscles trochanteric attachment. There were no significant differences in the inter-hip distance, the femoral head radius, the femoral neck length and the femoral neck-shaft angle angle. Hips contralateral to the slipped ones had a more vertically inclined physeal angle (55.4 vs. 63.2 degrees; p < 0.001) in comparison to the healthy hips. The Wiberg centre-edge angle of the hips contralateral to the slipped ones was on average 7% larger from the healthy group (34.7 vs. 32.2 degrees; p = 0.003). Children with hips at risk for slipping had larger pelvices and femora with more vertically inclined femoral epiphyseal growth plate. In addition, one cannot overlook the significant difference in the body weight between the age- and gender-matched groups of our study, confirming previous findings on the role of body weight in SCFE. It is therefore possible that anatomical changes may be a downstream effect of bone remodelling caused by altered loading during growth and development. This may suggest that the predisposition of the hip to slipping occurs earlier in the patient’s lifetime and that targeted radiographic examinations in obese individuals could reveal changes in pelvic geometry even before adolescence. Considering the high rates of bilateral involvement, our results could be used to predict the need for preventive fixation of asymptomatic hips after the capital femoral epiphysis has slipped in the contralateral hip


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_III | Pages 291 - 291
1 Nov 2002
Eduardo DB Vidal DL Mariano DD Patricia DP Jorge DG
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Our objective is to show the results of the unstable slipped capital femoral epiphysis treatment with reduction and threaded screw fixation. A retrospective analysis of 21 patients (13 boys and 8 girls) with unstable slipped capital femoral epiphysis was performed between 1993 and 1998. The right hip was involved in 13 patients and the left hip in 8. The patients presented acute pain and functional difficulties. The diagnoses were based on the clinical presentation, neutral and Lowestein hip x-rays. The treatment consisted on gentle manipulative reduction of the unstable slip (flexion and internal rotation), threaded cannulated screw fixation on orthopaedic table and image intensifier control. Results showed 2 avascular necrosis, 2 bone shortening, 3 limited range of motion. The rest showed satisfactory clinical results in the short term


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_5 | Pages 10 - 10
1 Jul 2020
Saito M Kuroda Y Khanduja V
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Background. Slipped capital femoral epiphysis (SCFE) creates a complex deformity of the hip that can result in cam type of femoroacetabular impingement (FAI), which may in turn lead to the early development of osteoarthritis of the hip. The purpose of this study was to evaluate the existing literature reporting on the efficacy of hip arthroscopic treatment of patients with FAI secondary to SCFE. Methods. A systematic computer search was conducted based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines using Embase, PubMed (Medline), and Cochrane Library up to November 2019. Data such as patient demographics, surgical outcomes and complications that described arthroscopic surgery following FAI secondary to SCFE were retrieved from eligible studies. Two authors independently reviewed study inclusion and data extraction with independent verification. Results. Following filtration, seven studies were included in this review comprising 96 patients (100 hips). The mean age was 14.9 years (SD, 2.7), and 54.2% of the cases were male. Eighty seven percent patients had undergone previous procedures at the first diagnosis of SCFE. Slip severity at the time of performing hip arthroscopy was mild for 54%, moderate for 31% and severe deformity for 15%. The mean alpha angle corrections was 32.0° (SD, 6.0°), and the mean improvement of internal rotation angle at 90° flexion was 23.6° (sd, 9.5°). ModifiedHarris Hip Scores (mHHS) was most reported (n = 3 studies; 38 hips) of the clinical outcomes, and the mean improvement of mHHS was 22.0 (sd, 3.6). Complication rates were 10%, and revision rate was 6.0%. Conclusion. Patients with FAI secondary to SCFE undergoing arthroscopic treatment demonstrate improved improvement in clinical outcome, rotation of the hip and correction of the alpha angle. It remains to be seen whether this eventually leads to prevention of OA and avoiding arthroplasty in this group of patients


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 126 - 126
1 Mar 2006
Roehrig H Ihme N Niedhart C Staatz G Kochs A
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Purpose: To evaluate the vascularisation of the femoral head in children with slipped capital femoral epiphysis (SCFE) before and after surgery with use of contrast-enhanced MRI. Methods and Materials: 20 consecutive children, 13 boys and 7 girls, aged 9–15 years, with slipped capital femoral epiphysis, were included into the study. The classification of SCFE was performed traditionally due to the patient’s history, physical examination and findings of the radiographs. There were no pre-slips, 9 children had acute, 5 children had acute-on-chronic and 6 children had chronic SCFE. The MRI-examinations were performed in a 1.5 Tesla MR-scanner with use of the body coil and all postoperative MR-examinations were carried out within 4 weeks after surgery. The examination protocol included a coronal fat-suppressed STIR-sequence, a coronal contrast-enhanced T1-weighted spin-echo sequence and a sagittal 3D-gradient-echo (FFE) sequence. Morphology, signal intensities and contrast-enhancement of the femoral head were assessed retrospectively by two experienced radiologists in consensus. Results: Morphologic distortion of the physis, bone marrow edema in the metaphysis and epiphysis and joint effusion were the preoperative MRI-findings of slipped capital femoral epiphysis in each child. In 17 children, who underwent in situ-fixation with a single screw, and in one child, who underwent open reduction of the epiphysis, the vascularisation of the femoral head before and after surgery was normal. An avascular zone in the posterior-lateral aspect of the epiphysis was visible preoperatively in one child, which completely revascularized after open reduction and internal fixation of the epiphysis with two screws. One child with severe SCFE developed avascular necrosis of the femoral head after open reduction and corrective osteotomy through the physis. Conclusion: MRI allows for accurate evaluation of the femoral head vascularisation before and after surgery in children with slipped capital femoral epiphysis


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_8 | Pages 19 - 19
1 Aug 2020
Morash K Gauthier L Orlik B El-Hawary R Logan K
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Slipped capital femoral epiphysis (SCFE) is traditionally treated with in situ fixation using a threaded screw, leading to physeal arrest while stabilizing the femoral head. Recently, there has been interest in alternative methods of fixation for SCFE, aiming to allow growth and remodelling of the femoral neck postoperatively. One such option is the Free Gliding SCFE Screw (Pega Medical), which employs a telescopic design intended to avoid physeal compression. The objective of this study is to evaluate radiographic changes of the proximal femur following in situ fixation using the Free Gliding SCFE Screw. This study retrospectively evaluated 28 hips in 14 consecutive patients who underwent in situ hip fixation using the Free Gliding SCFE Screw between 2014 and 2018. Initial postoperative radiographs were compared to last available follow-up imaging. Radiographic assessment included screw length, articulotrochanteric distance (ATD), posterior sloping angle (PSA), alpha angle, head-neck offset (HNO) and head-shaft angle (HSA). Of the 28 hips reviewed, 17 were treated for SCFE and an additional 11 treated prophylactically. Average age at surgery was 11.7 years, with an average follow-up of 1.44 years. Screw length increased by 2.3 mm (p < 0.001). ATD decreased from 25.4 to 22.2 mm (p < 0.001). Alpha angle decreased from 68.7 to 59.8 degrees (p = 0.004). There was a trend towards an increase in HNO (p = 0.07). There was no significant change in PSA or HAS. There were three complications (two patients with retained broken guide wires, and one patient requiring screw removal for hip pain). With use of the Free Gliding SCFE Screw, there was evidence of screw expansion and femoral neck remodelling with short-term follow-up. More research is required to determine the long-term impact of these changes on hip function, and to aid in patient selection for this technology


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 42 - 42
1 Jan 2003
Tsuji M
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We treated patients with severe slipped capital femoral epiphysisor SCFE with a posterior tilt angle or PTA of greater than or equal to 60 degrees with a Sugioka transtrochanteric rotational osteotomy. We report on the clinical and radiologic results of tis method. The study was performed on 8 cases (including 9 hips) of slipped capital femoral epiphysis, for which transtrochanteric rotational osteotomy of femoral head (Sugioka method) was carried out in author’s department from 1987 to 1996. The age of onset ranged from 9 to 14 years old (average: 11.6 years). There were 4 boys (4 hips) and 4 girls (5 hips). The follow-up period ranged from 2 years to 10 years (average: 4.4 years). Three of the treated hips were classified as chronic and 6 as acute on chronic. Preoperative head-neck angle (HNA) was 64 – 83 degrees (average: 68 degrees). All patients were performed a transtrochanteric rotational osteotomy of the femoral head which is known as the Sugioka method. The rotational angle was from 70 degrees to 90 degrees. The presence of pain, postoperative range of motion, PTA on postoperative X-rays, avascular necrosis and osteoarthritic change were examined as part of the evaluation of the clinical results. Necrosis of femoral head was found in one case, while no pain was noted in the other cases, and the range of motion was generally satisfactory. In the radiologic results, PTA was improved to 10 – 25 degrees (average: 18.5 degrees). Necrosis of femoral head was observed in one hip, but the results were satisfactory in 7 cases (8 hips). These results suggest that this technique is useful for the treatment of severe cases of slipped capital femoral epiphysis