Introduction. Blunt trauma of the lower limb can lead to vascular injury causing devastating outcomes, including loss of limb and even loss of life. The primary aim of this study was to determine the limb salvage rate of patients sustaining such injuries when treated at Leeds General Infirmary (LGI) since becoming a Major Trauma Centre (MTC). Secondary aims included establishing the patient complications and outcomes. Materials and Methods. Retrospective analysis found that from 2013–18, 30 patients, comprising of 32 injured limbs, were treated for blunt trauma to the lower limb associated with vascular injury. Long-term functional outcomes were determined using postal and telephone questionnaires. Results. Twenty-four patients were male and 6 were female, their mean ages were 32 and 49 respectively. Of the 32 limbs, 27 (84%) were salvaged. Three limbs were deemed unsalvageable and underwent primary amputation; of the remaining 29 potentially salvageable limbs, 27 (93%) were saved. Eleven limbs had prophylactic fasciotomies, 3 limbs developed compartment syndrome – all successfully treated, and three contracted deep infections – one of which necessitated amputation. All but 1 patient survived their injuries and were discharged from hospital. Of the 15 questionnaire responses, self-reported limb function was understandably worse post-injury with patients experiencing mild pain on average. In addition, there was a long-standing psychological impact and the injuries altered many patients’ normal lives significantly, 10 experiencing financial difficulties and 6 having changed or lost jobs post-injury. Conclusions. Fortunately, 27 (84%) limbs were salvaged and nearly all patients survived these injuries when treated at an MTC. Whilst the number of complications was low, the future challenges these patients face are wide-ranging and significant

Introduction: Fractured scapula is rare because the scapula is mobile and well protected. We report the first prospective study in the literature of scapular fractures caused by blunt trauma. Patients: 67 consecutive patients (64 males and 3 females, with a mean age of 33 (8–60) years) were included between January 2003 and September 2004. Data regarding the mechanism of injury, associated injuries, the Injury Severity Score (ISS), the location of the scapular fracture, whether it was isolated or involved more than one part of the scapula, and the accuracy of radiographic modality used were analyzed. Results: 50 (75%) fractures were caused by road traffic accidents, 11 by afall from height, 4 from a fall from the same level and 2 by heavy object. 56 patients (84%) sustained associated injuries of which chest injury occurred in 48 (72 %) and was the most frequent. Many patients had more than one substantial chest injury. 30 (45%) patients had lung contusion, 27 rib fracture, 23 haemothorax and 22 pneumothorax. The abbreviated injury score for chest injury for the isolated fractures (n=41) was 2.1 (0–5) and for the combined fracture group (n=26) was 2.4 (NS). Other associated injuries were upper limb fractures in 29 patients, head and facial injuries in 25, 17 had pelvic fractures, lower limb fractures occurred in 16 patients, 15 had spinal fractures and 10 abdominal injuries. No brachial plexus or subclavian artery injury occurred. The mean ISS was 20 for both fracture groups. 41 (61%) of fractures were isolated. Of these, 31 (75%) involved the body of the scapula, 4 acromion, 2 glenoid, 2 coracoid, 1 neck and 1 spine. For the 26 combined fractures, the body was involved in 24 (92%), 13 the neck, 12 spine, 4 glenoid, 4 acromion and 3 coracoid. Plain chest X-ray was done in 63 patients and the scapular fracture was shown in 40 (63%). 42 patients had scapular X-rays and the fracture was seen in 35 (83%). The fracture was shown in all 42 patients that had computer tomography (CT) of the chest. The same was true for the 19 patients who had CT of the scapula. In total, CT was done in 61 (91%) of the 67 patients. Discussion; Scapular fracture has a high rate of associated injuries, mainly to the chest. Lung contusion, haemo- and pneumothorax were very frequent in our series compared with other reports. The liberal use of trauma CT protocols and the prospective nature of the study may explain this finding

Background /Methods: Abbreviated Injury Scale based systems; the ISS, NISS, and AISmax, are used to assess trauma patients. The merits of each in predicting outcome are controversial. A large prospective database was used to assess their predictive capacity using receiver operator characteristic curves. Results: 13,301 adult patients met the inclusion criteria. All systems were significant outcome predictors for sepsis, multiple organ failure (MOF), length of hospital stay, length of ICU admission and mortality (p 0.0001). NISS was a significantly better predictor than the ISS for mortality (p 0.0001). NISS was equivalent to the AISmax for mortality prediction and superior in patients with orthopaedic injuries. NISS was significantly better for sepsis, MOF, ICU stay and total hospital stay (p 0.0001). Analysis of the ROC curves revealed that the traditional ISS cut-offs for severity of 16, 25 and 50 should be increased to 20, 30 and 55 to provide patients with equivalent outcome. Conclusions: NISS is superior or equivalent to the ISS and AISmax for prediction of all investigated outcomes in a population of blunt trauma patients. As NISS is easier to calculate, its use is recommended to stratify patients for clinical and research purposes

Background: We aimed to study the relationship between the number of fractured scapular regions, and the severity and distribution of associated injuries in blunt trauma patients. Methods: 107 consecutive patients with fractured scapulae (100 males) with a mean age of 35 (8–65) years were prospectively studied between January 2003 and December 2005. Mechanism of injury, associated injuries, injury severity scale (ISS) and the number of anatomical scapular regions involved in each fracture were studied. Patients were divided into single-region, two-region fracture, and more than two-region fracture groups. Computer tomography was used for fracture classification in 99 patients and plain X-rays in the remaining 8. Results: Road traffic collisions were the most common cause of scapular fracture. 95 patients (89%) sustained associated injuries. The most frequent was chest injury (68 (64%)). The median ISS was 9 (4–57) for the single-region fracture group (n 55), 20 (4–59) for the two-region fracture group (n 30), and 22.5 (4–54) for more than two-region fracture group (n 22) (p=0.02, Kruskal Wallis test). The median values of abbreviated injury scale (AIS) for chest injuries for the three groups were 1 (0–4), 3 (0–5) and 3 (0–5), respectively (p=0.001, Kruskal Wallis test). The single-region fracture group had significantly less posterior structure injury (9/55) compared with the multiple-region fracture group (46/52) (p=0, Fisher’s exact test). Conclusion: Associated injuries are common in patients having scapular fractures. ISS and AIS for chest injuries are higher and posterior structure injuries more frequent in patients with fractures involving multiple scapular regions

Cervical extrication collars are frequently used in pre hospital stabilization and in the definitive treatment for lesions of the cervical spine. The control of extensionflexion, lateral bending, and rotation given to individual segments is variable with different designs.

Objective: To highlight the patient satisfaction and reported pain perception with immobilization of cervical injury with the extrication collar.

Method: We present prospective cohort of fourteen patients with median age of 28 years with suspected C-spine injury waiting for CT scan. Unreliable patients were defined as those with admission Glasgow Coma Scale score < 15. They were treated with extrication collar immobilization. The initial diagnosis was made by supine cross-table lateral radiograph and then by computed tomographic scan as early as possible. All had no apparent neurologic deficit attributed to the C-spine at admission.

Results: All reported increased level of pain despite administering adequate analgesia. Most patients reported increased pain at the pressure point of the collar.

Conclusion: These cases demonstrate the limitations of current management techniques of suspected cervical fractures in unreliable trauma patients and highlight the lack of appropriate orthosis for cervical immobilization in our institution.

There is evidence that fracture healing is delayed in severely injured patients. We recently demonstrated that a blunt chest trauma, which induced posttraumatic systemic inflammation, considerably impaired fracture healing in rats. Because the complement anaphylatoxin C5a is an important trigger of systemic inflammation, we tested the hypothesis, whether the impairment of fracture healing observed after a severe trauma resulted from systemically activated complement. 16 male Wistar rats received a thoracic trauma and a femur osteotomy stabilized by an external fixator. Immediately and 12 h after the trauma, half of the animals received a C5aR-antagonist to prevent the C5a-dependent systemic inflammation. Control rats received a nonsense peptide, which does not provoke any biological effect. The animals were killed after 35 days and the calli were analyzed by three point bending testing, μCT and histomorphometry. Statistics: Mann-Whitney U test, level of significance to p<0.05. The treatment with the C5aR-antagonist increased flexural rigidity significantly by 55%, improved bony bridging of the fracture gap and led to a slightly larger and qualitatively improved callus as evaluated by μCT and histological measurements. This study shows, that the immunomodulation by a C5aR-antagonist significantly reduced the deleterious effects of a thoracic trauma on fracture healing. C5a could possibly represent a target to prevent delayed bone healing in patients with severe trauma

Background. Thoracolumbar fractures are the most common spinal injuries resulting from blunt trauma. Missed spinal injuries can have serious consequences. Objective. Our objectives were to determine the utility of trauma series chest and abdomen computed tomographs for detecting clinically unrecognised vertebral fractures and to analyse those missed on clinical examination. The aim was to identify an ‘at-risk’ patient group with negative clinical examination warranting evaluation with CT screening. Material and Methods. We evaluated all computed tomography of the chest and/or abdominal that was undertaken for blunt trauma at our trauma centre from April 2009 to April 2010. Data was gathered from both CT scans and medical notes to capture demographics, mechanism of injury, fracture site and configuration. Key points were the clinical suspicion of vertebral fractures prior to CT request and identifying ‘at-risk’ patient group with factors contributing to difficulty in clinical interpretation. Results. There were a total of 303 patients in the year who underwent CT scan for blunt trauma. 51(16.8%) had a thoracolumbar vertebral fracture. There were 8 women and 43 men a mean age of 45.2 years. There were 29 (56.8%) stable and 22 (43.2%) unstable fractures. Out of the 51 total fracture patients, only 17(33.3%) had been clinically anticipated with a positive clinical examination. In the 22 unstable fractures, only 11 (50%) were expected and had clinically recorded correlating positive examination findings. Conclusion. A combination of both clinical examination and CT screening based on mechanism will likely be required to ensure adequate sensitivity with an acceptable specificity for the diagnosis of clinically significant injuries of the TL spine

Aim. The knee radiograph is a commonly requested investigation as the knee joint is commonly injured. Each radiograph exposes 0.01mSv of radiation to the patient that is equivalent to 1.5 days of natural background radiation. Also, each knee radiograph costs approximately £37.16 to produce. The aim of the clinical audit was to use the Pittsburgh knee rules to attempt to reduce the number of knee radiographs taken in patients with acute knee injuries and hence reduce the dose of ionising radiation the patient receives. Method. A retrospective audit was undertaken. 149 knee requests and radiographs taken during October 2016 were evaluated. Each knee radiograph request including patient history and clinical examination was graded against the Pittsburgh knee rules to give a qualifying score. The Pittsburgh knee rules assigns 1 point for each of the following; blunt trauma or a fall, age less than 12 years or over 50 years, and unable to take 4 limping weight bearing steps in the emergency department. A Pittsburgh knee rule qualifying score warranting a knee radiograph is 2 or more points, where the patient must have had blunt trauma or a fall. A Pittsburgh knee rule score less than 2 points predicts a non-fractured knee and hence no radiograph warranted. Each radiograph was reviewed if a fracture was present or not. Results. The clinical audit identified 85 true negative patients where their Pittsburgh knee rule score was less than 2 points and they did not have a fracture of the knee joint. The Pittsburgh knee rule score of less than 2 points did not warrant obtaining knee radiographs. Therefore, a total of 85 knee radiographs were unnecessary which is equivalent to 127.5 days of background radiation. The financial burden of these unnecessary radiographs is £2648.60. The negative predictive value of the Pittsburgh knee rules in this audit was 93.4%. Discussion. The clinical audit shows that the use of the Pittsburgh knee rules scoring system can reduce the number of knee radiographs obtained by 57.4% and hence the doses of ionising radiation patients are exposed to. The audit also showed this clinical scoring system has a high negative predictive value that when utilised can discern patients with a normal knee joint who do not require a knee radiograph. In conclusion employing the Pittsburgh knee rule scoring system can improve patient safety by reducing ionising radiation exposure and can reduce financial costs of patient encounters

Cryotherapy is often applied after injuries of synovial joints. Although positive clinical effects on periarticular swelling and pain are well known, the effects on molecular processes of cartilage and synovial cells remained largely unknown so far. Therefore, the hypothesis was tested that hypothermia alleviates the synovial reaction and prevents chondrocyte death as well as cartilage destructive processes after blunt trauma. Human articular cartilage and synovial tissue was obtained with informed consent from patients undergoing knee joint replacement. Cartilage explants from macroscopically intact cartilage were impacted by a drop-tower apparatus with defined energy (0.59J) and cultivated for 24h or 7d at following temperature conditions: 2h, 16h or throughout at 27°C and afterwards or throughout at 37°C. Furthermore, human fibroblast-like synoviocytes (FLS) were stimulated with conditioned medium from traumatized cartilage (t-CM) and cultivated as indicated above up to 4d. Effects of hypothermia were evaluated by live/dead assay, gene expression (RQ-PCR), and type II collagen synthesis/cleavage as well as release of MMP-2, MMP-13 and IL-6 on protein level (ELISA, gelatin zymography). Statistical analysis was performed by 2-way ANOVA. The experimental study was performed in the research laboratory of the Orthopedic Department, University Hospital Ulm, Germany. Hypothermic treatment significantly improved chondrocyte viability 7d after blunt cartilage trauma (2h: p=0.016; 16h: p=0.036; throughout: p=0.039). 2h posttraumatic hypothermia attenuated expression of MMP-13 (m-RNA: p=0.012; protein: p=0.024). While type II collagen synthesis was significantly increased after 16h hypothermia, MMP-13 expression (mRNA: p=0.003; protein: p<0.001) and subsequent cleavage of type II collagen (p=0.049) were inhibited. Continuous hypothermia for 7d further significantly suppressed MMP release (proMMP-2, active MMP-2 and MMP-13) and type II collagen breakdown. On day 4 t-CM stimulated FLS revealed significantly suppressed gene expression of matrix-destructive enzymes (16h: ADAMTS-4; throughout: ADAMTS-4, MMP-3, MMP-13) and by trend reduced IL-6 expression in case of 16h or continuous hypothermia. Overall, hypothermia for only 2h and/or 16h after blunt cartilage trauma exhibited significant cell- and matrix-protective effects and promoted anabolic activity of surviving chondrocytes. Expression of matrix-destructive enzymes by FLS stimulated with Danger Associated Molecular Patterns (DAMPs) released from traumatized cartilage was attenuated by more prolonged hypothermia. These findings suggest that an optimized cryotherapy management after cartilage trauma might have the potential to ameliorate early molecular processes usually associated with the pathogenesis of posttraumatic osteoarthritis

Introduction: Road side accidents resulting in polytrauma with an associated fracture of femur is a common pattern of injury in asian countries. We hypothesised that the use of unreamed nailing in the management of such fractures has better outcome than reamed nailing. Material and Methods: We retrospectively reviewed 116 cases of polytrauma with associated fracture of shaft of femur admitted in our tertiary teaching hospital in North India bewteen Jan 1996 to Dec 2001. The patients were initially resuscitated according to the advanced trauma life support protocol. They were randomally managed by interlocking nail using reamed (n=48) and unreamed (n=68) technique after being haemodynamically stabilized. Five intraoperative parameters were recorded – the surgical time, fluoroscopy time, the intraoperative blood loss, intraoperative oxygen saturation, and any intraoperative complications. The patients were assessed postoperatively for ninety six hours for features of adult respiratory distress syndrome. All patients were clinically and radiologically assessed at 6 weekly intervals till union. The follow-up reassessments were performed by a single surgeon (AG). Results: There were 80 males, 30 females (6 were bilateral), with an average age of 26 years (range 19 to 64 years). The fractures were closed in 74 and open in 42 (Gustillo Grade 1;n=28, Grade 2;n=9, Grade 3;n=5). 48 were managed by reamed interlock nailing (Group 1) and 68 by unreamed interlock nailing (Group 2). 58 patients had an associated blunt trauma chest, 36 had blunt trauma abdomen, 18 had an associated head injury and 12 had spine injuries. The average surgical time for Group 1 was 118 minutes and for Group 2 was 94 minutes (p=0.014). The average fluorscopy time for Group 1 was 4.30 minutes and for Group 2 was 4.06 minutes. The average intra-operative blood loss for Group 1 was 254 millilitres and for Group 2 was 202 millilitres. The average intraoperative oxygen saturation fall as measured at the time of reaming and nail insertion was 2% in Group 1 and 6% in Group 2. The intraoperative complications were 11 (22.91%) in Group 1 and 18 (26.47%) in Group 2. The features of ARDS were observed in 6 patients in Group 1 (12.5%) and 4 patients in Group 2 (5.88%). The average union time was 25 weeks in Group 1 as compared to 19.4 weeks in Group 2 (p=0.012). The reoperation rate was 6.25% in Group 1 and 11.76% in Group 2. Discussion: The unreamed interlock nailing is the definitive management of fractures of femur in patients with polytrauma or blunt trauma chest as it requires lesser operative time (and thus exposing the patient to shorter period of anaesthesia), lesser blood loss and lesser fluoroscopy exposure. The incidence of ARDS is significantly lower with unreamed nailing in polytrauma patients. However the union time was significantly longer in unreamed nailing as compared to reamed nailing

Rib fractures (RF) represent the most common bone fracture after blunt trauma, occurring in 10–20% of all trauma patients and leading to concomitant injuries of the inner organs in severe cases. However, a standardized classification system for serial rib fractures (SRF) does still not exist. Basic knowledge about the facture pattern of SRF would help to predict organ damage, support forensic medical examinations, and provide data for in vitro and in silico studies regarding the thoracic stability. The purpose of our study was therefore to identify specific SRF patterns after blunt chest trauma. All SRF cases (≥3 subsequent RF) between mid-2008 and end of 2015 were extracted from the CT database of our University Hospital (n=383). Fractures were assigned to anterior, antero-lateral, lateral, postero-lateral, and posterior location within the transverse plane (36° each) using an angular measuring technique (reliability ±2°). Rib level, fracture type (transverse, oblique, multifragment, infracted), as well as degree of dislocation (none, </≥ rib width) were recorded and each related to the cause of accident. In total, 3747 RF were identified (9.7 per patient, ranging from 3 (n=25) to 33 (n=1)). On average, most RF occurred in crush/burying injuries (15.9, n=13) and pedestrian accidents (12.2, n=14), least in car/truck accidents (8.8, n=76). Altogether, RF gradually increased from rib 1 (n=140) towards rib 5 (n=517) and then decreased towards rib 12 (n=49), showing a bell-shaped distribution. More RF were detected on the left thorax (n=2027) than on the right (n=1720). Overall, most RF were found in the lateral (33%) and postero-lateral (29%) segment. Posterior RF mostly occurred in the lower thorax (63%), whereas anterior (100%), antero-lateral (87%), and lateral (63%) RF mostly appeared in the upper thorax. RF were distributed symmetrically to the sagittal plane, showing a hotspot (up to 98 RF) at rib levels 4 to 7 in the lateral segment and rib level 5 in the antero-lateral segment. In the car/truck accident group, 47% of all RF were in the lateral segment, in case of frontal collision (n=24) even 60%. Fall injuries (n=141) entailed mostly postero-lateral RF (35%). In case of falls >3 m (n=45), 48% more RF were detected on the left thorax compared to the right. CPR related SRF (n=33) showed a distinct fracture pattern, since 70% of all RF were located antero-laterally. Infractions were the most observed fracture type (44%), followed by oblique (25%) and transverse (18%) fractures, while 46% of all RF were dislocated (15% ≥ rib width). SRF show distinct fracture patterns depending on the cause of accident. Additional data should be collected to confirm our results and to establish a SRF classification system

Introduction:. South Africa has a very sports orientated population and a high blunt trauma prevalence. In August 2008, we re-established the soft tissue knee service at our academic hospital. Our clinic is staffed by a sessional Consultant, a Registrar, and is overseen by a senior honorary Consultant. Here we present a review of our first 2 years experience. Methods:. The clinic operates on a referral basis. All patients have all their clinical and demographic data and referral data entered into a Soft Tissue Database. The Data for 2009 and 2010 data were collated and analysed. Results:. A total of 346 patients were assessed and treated, of which 162 received surgery during this period. Patient referrals originated from both the state and independent sectors, and were made by hospital specialists, physiotherapists, and general practitioners. The mean delay from referral to first consultation was 9 days, and the mean wait from first consultation to surgery was 6 weeks. Our 162 procedures comprised of ACL reconstructions (52), PCL reconstructions (5), multiple ligament reconstructions (10), and osteotomies (4), as well as other procedures (91). There were 6 recorded major complications. Discussion:. A referral based specialist clinic can be successfully operated in a government hospital, and deliver both high quality clinical care, and valuable training opportunities to our trainees. Although currently staffed by part-time staff we believe that we have the capacity for many more patients and believe that we are only treating a small percentage of those in need. We want to increase awareness and referrals

Guidelines for cervical trauma x-rays highlight the necessity for visualization of the C7-T1 junction. However, despite 15% of thoracolumbar fractures involving the T12 vertebra, less emphasis has been placed on ensuring the thoracolumbar junction or T12 vertebra is included on lumbar trauma radiographs. This may be due to an assumption that the lower thoracic spine will routinely be seen on lumbar x-rays. We aimed to determine the proportion of lumbar trauma x-rays that allowed adequate visualisation for fracture diagnosis. We retrospectively reviewed all lumbar spine radiographs for patients presenting with blunt trauma to the Victoria Infirmary, Glasgow from January 2007 to January 2009. Our criteria for an appropriate lumbar trauma x-ray were that the whole lumbar spine should be visualized as well as the whole T12 vertebra. From 583 lumbar radiographs reviewed, 61 (10%) did not fulfill the criteria for an acceptable lumbar trauma x-ray. 3% did not include the lumbrosacral junction and 7% did not include the T12 vertebra. One patient had a delayed diagnosis of a T12 fracture due to incomplete visualisation of the T12 vertebra on initial lumbar radiographs. A significant proportion of lumbar spine x-rays performed for trauma patients (up to 10%) may not allow adequate visualisation for fracture diagnosis. These x-rays may give false reassurance that no fracture is present and, in turn, may lead to potentially disabling consequences. Spinal imaging for trauma patients should be interpreted closely with clinical findings. In cases where there is difficulty visualising the lumbar spine appropriately with radiographs, a CT scan should be considered

The early diagnosis of the suprascapular nerve (SSN) entrapment in overhead athletes with simultaneous shoulder injuries and its arthroscopic release plays an important role for their appropriate treatment and recovery. SSN release at suprascapular and spinoglenoid notches, seems very helpful for increasing their performance. 21 Elite overhead athletes were treated from Jan 2005–May 2009. From 16 to 34 years old, mean 26 years, 4 Javelin throwers (Olympic and National level thrower), 4 Weightlifters (International level), 8 Volleyball Players, 3 Kick Boxer, 2 Water Polo Players. Extreme ROM of arm creates large torques about the shoulder cycle of repetitive microtrauma to the SSN, Direct trauma: fracture, dislocation, blunt trauma traction injury, Sling effect with hyper-abduction injury at the SS Notch, Correlation ROM with SSN entrapment in volley ball players, Eccentric contraction of the ISP (spinoglenoid notch), Internal impingement, Rotator cuff tears, Biceps lesions, Instability, SLAP lesion, Bankart lesion, Mainly infraspinatus muscle atrophy. X-rays, Nerve conduction studies, EMG studies, MRI. All of them had complete pain relief, especially at the posterior shoulder, regained full ROM of the operated shoulder, 19 fully recovered at the pre-injury level, 2 at the postoperative phase, Muscle atrophy improved. Advanced SSN entrapment provoke significant muscle wasting, often irreversible. This underscores the importance of a quick and accurate diagnosis to appropriate intervention. The overhead athletes with increased ROM of their shoulder predispose in SSN entrapment and shoulder injuries and vice-versa. An arthroscopic shoulder procedure for repairing the glenohumeral pathology with a simultaneous arthroscopic SSN release seems to be the appropriate treatment regarding to our resu

The conflict in Iraq has evolved from a conventional war in April 2003 to a guerrilla-based insurgency. We investigated whether this change altered the pattern of wounding and types of injuries seen in casualties presenting to a military field hospital. From January 2006 – October 2006, data was collected on all casualties who presented to the sole British field hospital in the region following injury from hostile action (HA). 86 casualties presented with injuries from hostile action (HA). 3 subsequently died of wounds (DOW – 3.5%). 46 (53.5%) casualties had their initial surgery performed by British military surgeons. 20 casualties (23.2%) sustained gunshot wounds, 63 (73.3%) suffered injuries from fragmentation weapons and 3 (3.5%) casualties sustained injury from blunt trauma. These casualties sustained a total 232 wounds (mean 2.38) affecting an average 2.4 anatomical locations per patient. The current insurgency illustrates the likely evolution of modern urban conflict. Discrete attacks from improvised explosive devices (IED’s) have become the predominant cause of injury. These tactics have been employed against both military and civilian targets. With the current threat from terrorism, both military and civilian surgeons should be aware of the spectrum and management of the injuries caused. Correspondence should be addressed to Major M Butler RAMC, Princess Elizabeth Orthopaedic Centre, Royal Devon and Exeter Hospital, Exeter, Devon

Traumatic disruption of the pelvic ring has a high risk of mortality. These injuries are predominantly due to high-energy, blunt trauma and severe associated injuries are prevalent, increasing management complexity. This population-based study investigated predictors of mortality following severe pelvic ring fractures managed in an organised trauma system. Cases aged greater than 15 years from 1st July 2001 to 30th June 2008 were extracted from the population-based state-wide Victorian State Trauma Registry for analysis. Patient demographic, pre-hospital and admission characteristics were considered as potential predictors of mortality. Multivariate logistic regression was used to identify predictors of mortality with adjusted odds ratios (AOR) and 95% confidence intervals (CI) calculated. There were 348 cases over the 8-year period. The mortality rate was 19%. Patients aged greater than 65 years were at higher odds of mortality (AOR 7.6, 95% CI: 2.8, 20.4) than patients aged 15–34 years. Patients hypotensive at the scene (AOR 5.5, 95% CI: 2.3, 13.2), and on arrival at the definitive hospital of care (AOR 3.7, 955 CI: 1.7, 8.0), were more likely to die than patients without hypotension. The presence of a severe chest injury was associated with an increased odds of mortality (AOR 2.8, 95% CI: 1.3, 6.1), while patients injured in intentional events were also more likely to die than patients involved in unintentional events (AOR 4.9, 95% CI: 1.6, 15.6). There was no association between the hospital of definitive management and mortality after adjustment for other variables, despite differences in the protocols for managing these patients at the major trauma services (Level 1 trauma centres). The findings highlight the importance of the need for effective control of haemodynamic instability for reducing the risk of mortality. As most patients survive these injuries, further research should focus on long term morbidity and the impact of different treatment approaches

Our aim was to investigate the incidence and outcome of chest injuries after blunt trauma in patients admitted in a level I trauma centre over a 6-year period. This is a review of prospectively collected data (1996–2002); part of the (TARN-UK) data. Patients divided in 6 subgroups based on the chest AIS. Univariate analysis identified factors predicting mortality and a backward stepwise logistic regression multivariate analysis determined relationships with outcome. There were 1,164 patients with chest injuries. The mean overall severity of chest injuries was 3.15+/−1.01. The commonest mechanism of injury was RTAs (57.01%). Rib fractures were the most common injuries (395 patients, 34%) associated with lung contusions in 12.9%. Admission GCS was highest in chest-AIS subgroup 2 and was significantly higher in groups 1 and 3. Complications, invasive operations, and investigations were more common with increasing chest-AIS. The ICU-admissions and the mean length-of-stay were similar for chest-AIS1 and 2, but significantly higher for the rest. Half of the AIS1 patients had associated head injuries; the lowest percentage was in subgroup 2 (18.8%). There was a variable correlation of abdominal injury severity with severity of chest injury. There was a significant difference in mortality rates between group 2 and group 1 and -3. The average time to death in those with chest-AIS1 was significantly lower than the average time in those with AIS4 and 5. Patients in the higher AIS groups had both a higher overall ISS and mortality rate. Minimal chest injury severity (AIS1) showed higher ISS and significantly higher mortality compared with chest-AIS2,3. This has been attributed to the fact that the chest is spare as most of the impact during the course of the accident is been absorbed by the head (head injury). This theory also explains the shorter time period of death seen in patients belonging to the chest AIS1 group

Study objective: To validate the Ottawa Ankle Rules (OAR) to predict significant fractures in a Danish clinical setting. Methods: We designed an interventional clinical study in the emergency department, Kolding Hospital. The intervention and control groups consisted of all patients presenting with a blunt trauma of the ankle within 12 months. Patients in the first 6 months were included in the control group. The intervention consisted of a 45 minutes introduction to the OAR to the new group of junior doctors starting in the emergency department. Flyers and poster were distributed. There were 854 and 1006 patients respectively in the control and intervention group. Results: The main outcome of the study was a reduction in the number of preformed radiographs and an increase in diagnostic sensitivity. In the control group 62% of the patients were referred to radiographs, while only 57% in the intervention group. OAR had a sensitivity of 0.988, while the usual examinations techniques in the control group resulted in a sensitivity of 0.969. The use of OAR resulted in an increase in diagnostic specificity from 0.442 in the control group to 0.513 in the intervention group. The negative predictive value of OAR was 0.995. The rules failed in identifying 2 ankle fractures: a shaft fracture of the fifth metatarsal and 6 mm avulsion of the distal fibula. Both were diagnosed within the first week and treated conservatively, when returning to the hospital, as the OAR recommended in cases of no clinical improvement. When using the OAR, the radiology department would approximately perform 176 ankles and midfoot x-rays less a year, which is equivalent to 16%. Conclusion: Use of the OAR in a Danish clinical setting resulted in an increased diagnostic safety in detecting significant ankel fractures and in a reduction of unnecessary radiographs of the ankle and midfoot. We believe that the implementation of OAR could be beneficial to many emergency departments in Denmark and possibly in other similar settings

Background: Neutrophil (PMN) infiltration of the lung is characteristic of ARDS. Interleukin-8 (IL-8) plays a central role in the recruitment of PMN to the lung and their subsequent activation. This study examines PMN migratory activity in response to IL-8, over the first 24 hours of admissions following major trauma. Methodology: Study Population: Adult blunt trauma victims with ISS> /=18. PMN Migraoty Activity: PMN were isolated from citrated blood at admission, 8 and 24 hours later. The number of PMN migrating across porous tissue culture inserts in response to defined concentrations of IL-8 (zero, 10, 30 & 100ng/ml) were quantitated by peroxidase assay. Results: Significantly greater numbers of trauma patients PMN migrated to concentrations of IL-8 (30& 100ng/ml) at each time point, when compared to normal volunteers (Mann-Whitney-U Test p< 0.05). At admissions, and 8 hours later, PMN from those who later developed ARDS exhibit an enhanced migratory response to high concentrations of IL-8, in contrast to the noraml physiological attenuation of migration seen in both the remaining trauma patients (NAD) and normal volunteers (NLV). Discussion: These data indicate that major trauma fundamentally alters the migratory capacity of circulating PMN. Within 2 hours of admission, PMN show a unique pattern of activation in those who later develop ARDS, possibly due to alteration in IL-8 receptor expression, affinity or downstream signalling. These findings suggest that limiting PMN sequestration in the lung may represent a novel therapeutic target

Introduction Open calcaneal fractures are high-energy compression injuries that commonly result in dismal outcomes, despite appropriate care. Fracture pattern associated with these compound injuries have never been documented in detail. Plain radiographic studies and CT are imaging modalities commonly utilized to assess the fracture patterns. Methods The roentgenographic studies of thirty-nine consectutive compound fractures treated at our University Hospital were retrospectively reviewed to evaluate fracture subtypes and incidence. Hindfoot roentgenograms were performed in all individuals; more than three-fourths of the fractures were also assessed with CT. Results A vast array of fracture patterns was noted with variable incidence. Over 90% were intra-articular fractures. Eighty-seven percent resulted from blunt trauma - the remaining followed penetrating trauma. Six distinct fracture patterns were delineated. The fracture subtypes were stratified into low, intermediate and high levels of energy. Low energy (Type I) included minimally-displaced fractures. These comprised only eight percent of our series. Intermediate energy fractures (Type II) included tongue-type, thalamic fractures and reconstructible posterior facet fractures. These three subtypes comprised 69% of the series. Finally, the Type III, or high-energy fractures was made up of “pulverized fractures” and fracture-dislocations. These comprised 23% of our series. Conclusions Stratification of injury severity based on fracture subtypes and wound characteristics should assist orthopedists treating these compound hindfoot injuries. An injury classification is proposed combining a three part “energy of injury” scheme with a two-part “soft tissue” classification. A fuller understanding of the injury subtypes should help establish future management standards