Advertisement for orthosearch.org.uk
Results 1 - 1 of 1
Results per page:
Applied filters
Open access content
Include Proceedings
Access
Journals
Abstracts
Dates
Year From
Year To
Specialties
Bone & Joint Research
Vol. 2, Issue 10 | Pages 220 - 226
1 Oct 2013
Gentamicin in bone cement
Chang Y Tai C Hsieh P Ueng SWN
Full Access
View article Download PDF

Objectives

The objective of this study is to determine an optimal antibiotic-loaded bone cement (ALBC) for infection prophylaxis in total joint arthroplasty (TJA).

Methods

We evaluated the antibacterial effects of polymethylmethacrylate (PMMA) bone cements loaded with vancomycin, teicoplanin, ceftazidime, imipenem, piperacillin, gentamicin, and tobramycin against methicillin-sensitive Staphylococcus aureus (MSSA), methicillin-resistant Staph. aureus (MRSA), coagulase-negative staphylococci (CoNS), Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae. Standardised cement specimens made from 40 g PMMA loaded with 1 g antibiotics were tested for elution characteristics, antibacterial activities, and compressive strength in vitro.

Image linking to Orthomedia