Abstract
Summary Statement
This study assesses the service provision of viscosupplementation within an NHS (British National Health System) hospital. The results of this study show long term efficacy of the treatment, when provided by a dedicated, orthopaedic unit.
Introduction
The service provision of viscosupplementation for osteoarthritis within the National Health System (NHS) remains controversial. The treatment was recommended in the 2007 NICE guidelines but support was withdrawn the following year. Furthermore, whether it should be provided by orthopaedic surgeons or in primary care is also a matter of debate. St Helens and Knowsley Trust, runs an orthopaedic outpatient clinic dedicated to the administration of viscosupplementation to patients with symptomatic knee osteoarthritis. This study aims to assess the efficacy of viscosupplementation for knee osteoarthritis when that is provided by a highly specialised, orthopaedic, dedicated service
Patients and Methods
Between January 2011 and June 2011, 103 patients underwent Ostenil® intra articular knee injections in our clinic. The viscosupplement used is Ostenil®, a 20mg/2ml sodium hyaluronate as an isotonic solution contained in a single syringe.
Patients are given a regimen of 3 × 20mg/2ml Ostenil® injections. The time interval between injections is two weeks. They were all given a “pain diary” and were asked to document their pain score on a Visual Analogue Scale (from 0 to 10), prior to the treatment, the day of procedure and up to 3 months after the procedure. 72 patients (M:F 34:38, Mean age: 60.3 years) participated in the study (Right knee 31, Left 22 and Bilateral 19). Mean pre treatment and post treatment score amongst all patients were calculated up to three months post treatment.
Results
Results show a continuous decreasing trend in pain scores up to three months after the procedure. Indicatively, mean pre treatment pain score was 6.88, mean pain score on day 3 (2 days post first injection) is 4.89, mean pain score on Day 31 (2 days after 3rd injection) is 4.37. Pain levels are maintained low at Week 6 after treatment (4.43) and Month 3 (4.37). A small peak in pain score was identified up to 48hrs after the injections but that has been already identified in current literature as a result of short term inflammation due to the injection process.
Conclusion
Viscosupplementation for knee osteoarthritis is an efficient treatment when provided by an orthopaedic, dedicated service. The duration of the reduction in pain with a three injection course is at least 3 months. This study also demonstrates that an overall 3 injection course with a time interval of 2 weeks between injections is sufficient to produce long lasting results.
