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THE INFECTED TOTAL KNEE ARTHROPLASTY (TKA): RESULTS FROM 48 TWO-STAGE REVISION ARTHROPLASTIES (RESULTS AT 5.5 YEARS ON AVERAGE)



Abstract

Introduction: The current gold standard for the treatment of the infected total knee arthroplasty is a two-stage revision. The purpose of this study is to present our results with two-stage revision arthroplasty in a series of 48 infected TKAs.

Materials and Methods: Over a 10-year period (1996–2005) we have performed 2140 TKAs. Of them 48 (48 patients) were infected and required a two-stage revision arthroplasty (2.2% infection rate). In 43 patients of these patients we used LCCK prostheses (Zimmer, USA) and in 5 (with severe instability) a rotating hinge prosthesis (Waldemar Link, Germany). In 26 occasions antibiotics-loaded cement (Palacos with gentamicine) was used and in 22 we used articulated spacers. The average age of patients was 67 years (range, 59–82) and the average follow-up was 5.5 years (range: 1–10). The results were assessed according to the Knee Society scores.

Results: Four knees were re-infected. Results were excellent in 28 knees, good in 13, fair in 3 and poor in 4 (the four re-infected prostheses). The four infected prostheses had been treated by static spacers. The survival rate taking as end-point removal of components for infection is 91.6% (results at average of 5.5 years).

Conclusion: Our results confirm that two-stage revision TKA is a reproducible procedure in the infected primary TKA. Also that articulated antibiotic-loaded spacers seem to be better than static spacers.

Correspondence should be addressed to: EFORT Central Office, Technoparkstrasse 1, CH – 8005 Zürich, Switzerland. Email: office@efort.org