Abstract
Introduction: Tutobone is a solvent-preserved cancellous bovine bone substitute. There is little published about its use in humans. We have been using it as a wedge graft to correct deformity in hindfoot fusion surgery.
Aim: To review the outcome following the use of Tutobone in hindfoot fusion and compare it with a control group without Tutobone.
Method: We performed a retrospective review of all hindfoot fusion performed by the senior author (AG) from 1 Sep 2004 to 31 Jan 2008. We excluded all revision procedures for non-union or malunion. A CT or MRI scan was performed to assess union and graft incorporation in the Tutobone patients at more than six months postoperatively. In the control group fusion was assessed with plain radiographs. The difference in proportion of fusion with complete fusion by six months post-operatively was assessed with a Fisher’s exact test
Results: There were eleven patients in the Tutobone group (1 ankle, 7 subtalar and 3 triple fusions) and 35 in the control group (15 ankle, 11 subtalar, 3 pantalar and 6 triple fusions). All Tutobone patients had partial union on CT/MRI scans. The Tutobone graft had not incorporated at a mean time interval of 14 months post surgery. 30 out of 35 control patients had fused by six months and 33 out of 35 controls were fused by 12 months. The rate of complete fusion between the two groups at six months was statistically significant (p< 0.0001). Two Tutobone patients developed an inflammatory reaction at more than six months post fusion. This reaction is not infective and appears to be a reaction to the Tutobone.
Conclusion: Tutobone should not be used in hindfoot fusion surgery.
Correspondence should be addressed to A.H.N. Robinson, BOX 37, Department of Orthopaedics, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Trust, Hills Road, Cambridge. CB2 0QQ, England.
