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RESULTS OF ALLOGRAFTS AFTER CANCER SURGERY IN CHILDREN



Abstract

Introduction and Objectives: The success rate of bone allografts in the medium term when used in cancer surgery is 63% to 90% according to the different series. Our aim was to analyze the results and the complication rate seen in bone allografts as used in our center.

Materials and Methods: We collected follow-up data from 35 patients who received 37 allografts. The variables analyzed include diagnosis, age, bone and side affected, type of allograft, complications, additional surgery, time of follow-up, and allograft and patient survival.

Results: Mean age at surgery: 10.6 years. 48.64% were osteosarcomas, 48.64% were Ewing sarcomas, 2.7% were other diagnoses. 52.94% were strut grafts, 29.41% were osteoarticular, 2.94% were composite, 2.94% were arthrodesis and 11.76% were other types. Of these, 88.88% suffered some type of complication and 81. 48% required additional surgery. We achieved allograft survival in 85.29% of cases with a mean follow-up of 55.45 months. Most frequent complications were non-union (25%), postoperative metastasis (25%) length discrepancy (25%), followed by degenerative arthritis (24%) graft resorption and infection (16.6%)

Discussion and Conclusions: Allografts are a reconstructive option with good results in the medium term. In spite of the high complication rate, additional surgeries applying rescue procedures have made it possible to obtain allograft survival similar to that seen in published series.

The abstracts were prepared by E. Carlos Rodríguez-Merchán, Editor-in-Chief of the Spanish Journal of Orthopaedic Surgery and Traumatology (Revista Española de Cirugía Ortopédica y Traumatología). Correspondence should be addressed to him at: Sociedad Española de Cirugía Ortopédica y Traumatología, calle Fernández de los Ríos 108, 28015-Madrid, Spain