MENISCAL ALLOGRAFT TRANSPLANTATION: LONG-TERM CLINICAL RESULTS WITH MEAN FOLLOW UP OF 10 YEARS

Abstract

BACKGROUND: The purpose of this study was to evaluate the long term results of meniscal transplantation in a consecutive series of younger patients treated for pain in the tibiofemoral compartment following a previous meniscectomy.

METHODS: One hundred and thirty eight (138) menisci were implanted into one hundred and thirty-five (135) patients over a sixteen year period.

Seventy five (75) knees also had an associated osteotomy, and eleven (11) had a ligament reconstruction. The clinical outcome using pain and functional knee scores and failure rate of all transplants was evaluated at a mean 10.2 years (2–16 years) postoperatively.

RESULTS: One hundred and twenty (120) patients with one hundred and twenty three (123) meniscal grafts were available for final follow up. Fifteen (15) patients were lost to follow up. Seventy five percent (75%) of patients had an improvement in pain knee score and seventy one percent (71 %) of patients had an improvement in functional knee score.

Twenty patients (16.6%) underwent a total knee replacement at a mean interval of 9.3 years after the meniscal transplant.

Patients with isolated meniscal transplantation had the most improved clinical outcome.

Patients with concomitant knee osteotomy and knee ligament reconstruction procedures also had improved knee function without an increase the rate of complications.

CONCLUSIONS: The long-term results of meniscal transplantation are encouraging in terms of reducing knee pain and increasing function at a mean follow up of 10.2 years. Patients with isolated meniscal transplantation have improved outcomes.