Abstract
Introduction: The incidence of femoral neck fracture is approximately 2% after resurfacing hip replacement. Avascular necrosis is thought to be a contributory factor. The aim of this study was to investigate oxygen concentration in the femoral head during metal-on-metal hip resurfacing (MMHR).
Materials and Methods: In ten patients, following division of the fascia lata, a calibrated gas-measuring electrode was inserted into the supero-lateral quadrant of the femoral head via the femoral neck. Xsrays confirmed placement of the electrode 2-3 cms below the femoral head surface. Baseline oxygen concentration levels were recorded immediately upon electrode insertion and used as a reference for all intra-operative measures. Oxygen levels were monitored continuously throughout the operation.
Results: Oxygen concentration was reduced during the surgical approach and average oxygen concentration following dislocation and circumferential capsulotomy dropped significantly (p< 0.005) to 38% of baseline (SD=26%). Insertion of implants resulted in a further significant drop in oxygen concentration (p< 0.04) to 21% of baseline (SD=28%). Oxygen concentration rose slightly, but not significantly after relocation of the resurfaced joint and reconstruction of posterior soft tissues, reaching 22% of initial baseline oxygen levels. Considerable variation between subjects was observed.
Discussion: Intra-operative measurement of oxygen concentration in blood perfusing the femoral head is possible. During MMHR there is a dramatic decrease in femoral head oxygenation during surgical approach and implant fixation. This may increase the risk of avascular necrosis and subsequent femoral neck fracture. Future experiments will determine if a different surgical approach can protect the blood supply to the femoral head and neck. Measurements of femoral head oxygenation during metal-on-metal hip resurfacing demonstrated a significant concentration decrease during surgical approach and implant fixation.
Editorial Secretaries: Lynne C. Jones, Ph.D.* and Michael A. Mont, M.D. Address for Correspondence: *Lynne C. Jones, Ph.D., Suite 201 GSH POB, 5601 Loch Raven Blvd., Baltimore, MD 21239, USA. Email: ljones3@jhmi.edu