The Gorham-Stout syndrome (Gorham’s massive osteolysis): A REPORT OF SIX CASES WITH HISTOPATHOLOGICAL FINDINGS

G. Möller; M. Priemel; M. Amling; M. Werner; A. S. Kuhlmey; G. Delling

doi:10.1302/0301-620X.81B3.0810501

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The Gorham-Stout syndrome (Gorham’s massive osteolysis)

A REPORT OF SIX CASES WITH HISTOPATHOLOGICAL FINDINGS

G. Möller
M. Priemel
M. Amling
M. Werner
A. S. Kuhlmey
G. Delling

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The Gorham-Stout syndrome (Gorham’s massive osteolysis)

Möller G, Priemel M, Amling M, Werner M, Kuhlmey AS, Delling G. The Gorham-Stout syndrome (Gorham’s massive osteolysis). J Bone Joint Surg Br. 1999;81-B(3):501-506. doi:10.1302/0301-620X.81B3.0810501

Möller, G., et al. “The Gorham-Stout syndrome (Gorham’s massive osteolysis).” The Journal of Bone & Joint Surgery British Volume, vol. 81-B, no. 3, 1999, pp. 501-506., https://doi.org/10.1302/0301-620X.81B3.0810501

Möller, G., Priemel, M., Amling, M., Werner, M., Kuhlmey, A. S., & Delling, G. (1999). The Gorham-Stout syndrome (Gorham’s massive osteolysis). The Journal of Bone & Joint Surgery British Volume, 81-B(3), 501-506. https://doi.org/10.1302/0301-620X.81B3.0810501

Möller, G., Priemel, M., Amling, M., Werner, M., Kuhlmey, A. S. and Delling, G. (1999) “The Gorham-Stout syndrome (Gorham’s massive osteolysis).” The Journal of Bone & Joint Surgery British Volume, 81-B(3), pp. 501-506. Available at: https://doi.org/10.1302/0301-620X.81B3.0810501

Möller, G., M. Priemel, M. Amling, M. Werner, A. S. Kuhlmey, and G. Delling. “The Gorham-Stout syndrome (Gorham’s massive osteolysis).” The Journal of Bone & Joint Surgery British Volume 81-B, no. 3 (1999): 501-506. https://doi.org/10.1302/0301-620X.81B3.0810501

Möller G, Priemel M, Amling M, Werner M, Kuhlmey AS, Delling G. The Gorham-Stout syndrome (Gorham’s massive osteolysis). J Bone Joint Surg Br. 1999 May 1;81-B(3):501-506. https://doi.org/10.1302/0301-620X.81B3.0810501

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Abstract

The Gorham-Stout Syndrome (Gorham’s massive osteolysis) is a rare condition in which spontaneous, progressive resorption of bone occurs. The aetiology is poorly understood. We report six cases of the condition and present evidence that osteolysis is due to an increased number of stimulated osteoclasts. This suggests that early potent antiresorptive therapy such as with calcitonin or bisphosphonates may prevent local progressive osteolysis.

Correspondence should be sent to Professor G. Delling.

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